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INDONESIA
Indonesian Journal Health Science and Medicine
Published by Universitas Muhammadiyah Sidoarjo
ISSN : -     EISSN : 30638186     DOI : https://doi.org/10.21070/ijhsm
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health Veterinary
Focus: The Indonesian Journal on Health Science and Medicine (IJHSM) focus to advance the field of health science and medicine by publishing high-quality, peer-reviewed research articles, reviews, and case studies. Our journal serves as a platform for researchers, clinicians, and healthcare professionals to share innovative findings, critical insights, and emerging trends in the broad domain of health science and medicine. Scope: Clinical Research and Practice Studies on the diagnosis, treatment, and prevention of diseases. Clinical trials and evidence-based practices. Advances in medical technology and therapeutics. Public Health Epidemiology and health statistics. Health policy and management. Community health initiatives and health education. Biomedical Science Research on cellular and molecular biology. Genetics and genomics. Pharmacology and toxicology. Health Care Systems and Services Health care delivery and management. Quality improvement in health care services. Health economics and health informatics. Global Health Health issues affecting populations worldwide. International health regulations and practices. Global health governance and diplomacy. Health Promotion and Disease Prevention Lifestyle and behavioral interventions. Preventive medicine and early detection. Nutritional science and physical activity. Mental Health Research on mental health disorders and treatments. Psychological well-being and mental health promotion. Integration of mental health services in primary care. Innovations in Health Education and Training Medical and health science education methodologies. Training programs for health professionals. Continuing education and professional development.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 311 Documents
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Cardiovascular Disease Risk after COVID-19 in Diabetic and Non-Diabetic Adults: A Study in Iraq : Risiko Penyakit Kardiovaskular Pasca COVID-19 pada Orang Dewasa Penderita Diabetes dan Non-Diabetes: Sebuah Studi di Irak Hamza, Hussein Jaber
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.425

Abstract

General Background: COVID-19 has emerged as a global health crisis with significant implications for patients with underlying cardiovascular conditions. Specific Background: Increasing evidence indicates that cardiovascular disease is associated with severe outcomes and complications in infected individuals. Knowledge Gap: Despite numerous studies, there remains a need to synthesize findings on cardiovascular risks and outcomes in diverse populations. Aims: This study aims to analyze the relationship between COVID-19 and cardiovascular disease, focusing on risk factors, clinical manifestations, and outcomes. Results: The findings indicate that patients with pre-existing cardiovascular conditions are more likely to experience severe disease, higher mortality, and long-term complications. Novelty: The study consolidates evidence from multiple studies to provide a comprehensive overview of cardiovascular risks in COVID-19 patients. Implications: These findings support the need for targeted clinical management and preventive strategies for vulnerable populations, contributing to improved healthcare planning and patient care. Keywords: Covid-19, Cardiovascular Disease, Clinical Outcomes, Risk Factors, Mortality Key Findings Highlights Pre-existing conditions are associated with severe cases and complications Multiple studies report elevated mortality among affected patient groups Long-term health issues remain a significant concern after infection
The Protection Evaluation by The Grape-Seed-Loaded PVA/Chitosan Nanofiber Scaffolds on UV-Induced Skin Damage in Rabbits: Evaluasi Perlindungan oleh Kerangka Nanofiber PVA/Kitosan yang Diperkaya Biji Anggur terhadap Kerusakan Kulit Akibat Sinar UV pada Kelinci Sadiq, Dina H.; Majeed, Majdy Faisal; Mhalhal, Thaar R.; Abdullah, Prof. Dr. Ali Qassim
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.426

Abstract

General Background: Ultraviolet radiation is a major environmental factor causing oxidative stress, cellular damage, and structural deterioration in skin tissue. Specific Background: Recent advances in nanofiber technology have enabled the development of biomimetic scaffolds capable of delivering bioactive compounds for tissue repair and regeneration. Knowledge Gap: Limited experimental evidence exists on the combined use of PVA/chitosan nanofibers loaded with grape seed extract for restoring UV-damaged skin structure and antioxidant balance. Aims: This study aimed to evaluate the protective and therapeutic performance of grape-seed-loaded PVA/chitosan nanofiber scaffolds in a rabbit model exposed to chronic ultraviolet radiation. Results: The fabricated nanofibers demonstrated strong molecular interactions and uniform morphology, while biological evaluation showed that UV exposure induced severe oxidative, morphological, and histological damage. Treatment with the nanofiber scaffold for seven days led to restoration of skin architecture, reduction of inflammation and fibrosis, and significant improvement in antioxidant activity as confirmed by ABTS and DPPH assays. Novelty: This study demonstrates the successful integration of grape seed extract into nanofiber scaffolds with preserved structural integrity and functional bioactivity. Implications: The findings support the application of nanofiber-based systems as promising therapeutic platforms for skin regeneration and protection against ultraviolet-induced damage. KeywordsNanofiber Scaffold, Ultraviolet Radiation, Skin Damage, Grape Seed Extract, Antioxidant Activity Key Findings Highlights Uniform nanoscale fibers with stable molecular interactions achieved Severe tissue disruption observed after prolonged radiation exposure Short-term treatment restored structural organization and antioxidant balance
Preeclampsia Screening Using BMI MAP and ROT Indicators: Skrining Preeklampsia Menggunakan Indikator BMI MAP dan ROT Hasna Rosyidah; Rafhani Rosyidah
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.427

Abstract

General Background Preeclampsia remains a major contributor to maternal morbidity and mortality worldwide. Specific Background Early detection strategies using clinical indicators such as Body Mass Index (BMI), Mean Arterial Pressure (MAP), and Roll Over Test (ROT) have been widely discussed in maternal health research. Knowledge Gap However, integrated assessment of these indicators in identifying preeclampsia risk is still limited in specific clinical settings. Aims This study aims to examine the role of BMI, MAP, and ROT in early screening of preeclampsia among pregnant women. Results The findings show that variations in BMI, MAP, and ROT measurements are associated with differences in preeclampsia risk classification. Novelty This study provides a combined perspective of three clinical indicators in preeclampsia screening. Implications The results highlight the importance of utilizing simple clinical measurements as part of early detection strategies in maternal healthcare services. Keywords: Preeclampsia, Body Mass Index,Mean Arterial Pressure, Roll Over Test, Maternal Health Key Findings Highlights Combined indicators identify varying risk categories Clinical measurements support early screening decisions Observed patterns assist risk classification in pregnancy
Acupressure and Health Education in Reducing Dysmenorrhea Pain: Akupresur dan Edukasi Kesehatan dalam Mengurangi Nyeri Dismenore Nabilah Fatya Tsabita; Siti Cholifah; Yanik Purwanti; SM Faridah Hanum
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.428

Abstract

General Background: Dysmenorrhea is a common reproductive health issue among adolescents that can interfere with daily activities and learning processes. Specific Background: Various non-pharmacological interventions, including acupressure and health education, have been explored as alternative approaches to manage menstrual pain among young women. Knowledge Gap: However, limited studies integrate both educational media and acupressure techniques as a combined approach to improve knowledge and reduce pain simultaneously. Aims: This study aims to examine the application of health education and acupressure techniques in addressing dysmenorrhea among adolescents. Results: The findings indicate that the intervention contributes to improved understanding of dysmenorrhea management and supports the reduction of pain intensity through non-pharmacological methods. Novelty: The study highlights a combined approach using educational media and acupressure practice as an integrated intervention model. Implications: These findings provide practical insights for implementing accessible and low-risk interventions in adolescent reproductive health programs, particularly in educational settings. The study also supports the development of preventive strategies through health promotion and self-care practices. Keywords: Dysmenorrhea, Acupressure, Health Education, Adolescents, Non Pharmacological Therapy Key Findings Highlights Combined intervention improves understanding of menstrual pain management Non-drug technique supports reduction of discomfort intensity Educational media strengthens self-care awareness among adolescents
Acupressure Application for Reducing Emesis Gravidarum in Early Pregnancy: Penerapan Akupresur untuk Mengurangi Muntah pada Kehamilan Awal Ela Nafiatul K; Evi Rinata; Siti Cholifah; Yanik Purwanti
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.429

Abstract

General Background: Emesis gravidarum is a common condition experienced by pregnant women in the first trimester and may disrupt daily activities. Specific Background: Non-pharmacological interventions such as acupressure have been widely explored as alternative management to reduce nausea and vomiting during pregnancy. Knowledge Gap: However, limited studies clearly describe the application and measurable outcomes of acupressure in managing emesis gravidarum in specific populations. Aims: This study aims to analyze the role of acupressure in reducing nausea and vomiting among first trimester pregnant women. Results: The findings indicate that acupressure application is associated with a decrease in the intensity of nausea and vomiting experienced by pregnant women. Novelty: This study highlights the use of specific acupressure points as a practical and non-invasive approach in maternal care. Implications: The results suggest that acupressure can be considered as an alternative complementary therapy in managing emesis gravidarum in clinical and community settings. Keywords: Acupressure, Emesis Gravidarum, Pregnancy, Nausea Vomiting, Complementary Therapy Key Findings Highlights Reduction in symptom intensity observed after intervention Non-invasive approach applicable in maternal care settings Practical technique suitable for early pregnancy management
Delay Time and Preservation Method in Urine Epithelial Examination: Waktu Penundaan dan Metode Penyimpanan dalam Pemeriksaan Epitel Urin Suci Purwati; Puspitasari
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.430

Abstract

General Background: Urinalysis is an essential diagnostic tool for detecting metabolic and urinary tract disorders, including complications in diabetes mellitus patients. Specific Background: In diabetes mellitus, urinary tract infections frequently occur and are associated with epithelial cell changes in urine sediment. Knowledge Gap: However, limited evidence exists regarding the effect of delayed examination and preservation methods on urine epithelial integrity. Aims: This study aims to analyze the effect of delay time and preservation methods on urine epithelial examination in diabetes mellitus patients. Results: Using an analytical experimental approach with 30 urine samples, the findings show that delayed examination at 4 and 5 hours leads to a decrease in epithelial cell count and morphological changes. Storage at 4°C demonstrates better preservation compared to the addition of 10% formaldehyde, although both methods show significant differences based on the Friedman test. Novelty: This study highlights the comparative outcomes of cold storage and formaldehyde preservation under delayed conditions in diabetic patient samples. Implications: The findings emphasize the importance of proper sample handling and timely examination to maintain the accuracy of urinalysis results in clinical laboratory practice. Keywords: Urinalysis, Epithelial Cells, Delay Time, Preservation Method, Diabetes Mellitus Key Findings Highlights Reduced cell counts observed with prolonged examination delay Cold storage maintained structural characteristics more consistently Preservative addition associated with morphological alteration
Assessment of Risk Factors Associated with Increased Incidence of Thalassemia in Najaf Governorate Sarah Abbood Shanan; Haidar Sahib Sharad; Noor Hadi Hassan
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.431

Abstract

General Background: Thalassemia is a common inherited hemoglobin disorder characterized by defective globin chain synthesis and widespread global distribution. Specific Background: The prevalence of thalassemia varies across regions and is influenced by demographic and hereditary factors, particularly in Middle Eastern populations. Knowledge Gap: Limited localized evidence exists regarding the specific risk factors contributing to thalassemia incidence in Najaf Governorate. Aims: This study aimed to identify demographic and genetic risk factors associated with increased thalassemia cases in Najaf. Results: A cross-sectional study of 167 patients revealed higher prevalence among males, children aged 1–10 years, and urban residents. Blood group O was most common, while Rh-positive status reflected general population trends. Parental consanguinity and positive family history showed strong associations with disease occurrence, and thalassemia major was more prevalent than minor forms. Novelty: This study provides localized epidemiological evidence highlighting the combined role of demographic and hereditary determinants in thalassemia distribution. Implications: The findings emphasize the importance of premarital screening, early diagnosis, and community awareness programs to reduce disease burden and improve health outcomes. Keywords: Thalassemia, Risk factors, Consanguinity, Epidemiology, Najaf Key Findings Highlights Higher cases observed in early childhood and urban populations Strong association between parental relatedness and disease occurrence Familial clustering evident through multiple affected siblings
Renal Dysfunction and Mineral Metabolism Disturbances in Elderly Patients with COVID-19: A Controlled Clinical Study Alaa Abed Faisal Faisal
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.432

Abstract

General Background: Coronavirus disease 2019 (COVID-19) is increasingly recognized as a multisystem disorder with notable renal and metabolic complications. Specific Background: While acute kidney injury during infection is well documented, persistent alterations in renal function and calcium–phosphate–vitamin D homeostasis after recovery, particularly in elderly individuals without comorbidities, remain insufficiently explored. Knowledge Gap: Limited case-control evidence exists integrating renal biomarkers and mineral metabolism parameters in older adults following SARS-CoV-2 recovery. Aims: This study aimed to assess long-term renal function and mineral metabolism disturbances and evaluate the diagnostic performance of related biomarkers in elderly men eight months post-COVID-19. Results: Compared to controls, post-COVID participants showed higher serum creatinine and blood urea and lower eGFR, alongside reduced serum calcium, inorganic phosphate, and 25-hydroxyvitamin D levels (p < 0.001). Individual biomarkers demonstrated strong discriminatory ability, while the combined multivariate model showed excellent discrimination, good calibration, and meaningful clinical utility. Renal indicators, particularly eGFR and blood urea, were the strongest predictors. Novelty: This study integrates renal and mineral biomarkers within an age-matched case-control framework, highlighting combined biomarker modeling for post-COVID assessment. Implications: Findings support sustained renal and metabolic monitoring in elderly populations after COVID-19 recovery and indicate the value of combined biomarker approaches for early detection of post-infectious renal involvement. Highlights:• Persistent kidney filtration abnormalities observed eight months after recovery• Marked disruption in calcium, phosphate, and vitamin D balance detected• Combined biomarker model shows strong diagnostic discrimination and clinical utility Keywords: COVID-19, Renal Dysfunction, Mineral Metabolism, eGFR, Vitamin D
Determinants of Uromodulin Levels among Patients with Type 2 Diabetes Mellitus Muntadher Al Bahhash; Abrar I. Albadr; Abdulhussein Aljanabi
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.433

Abstract

General Background: Uromodulin, a kidney-specific glycoprotein, is associated with renal function and is frequently reduced in diabetes and chronic kidney disease. Specific Background: In type 2 diabetes mellitus, metabolic disturbances contribute to tubular injury, with declining uromodulin levels observed during disease progression. Knowledge Gap: However, the relationships between uromodulin levels and demographic and clinical determinants such as age, gender, body mass index, glycemic control, and duration of diabetes remain insufficiently clarified. Aims: This study aimed to evaluate the association between uromodulin levels and these variables in patients with type 2 diabetes mellitus. Results: A case-control study involving 176 participants demonstrated significant variations in uromodulin levels (p<0.001), with lower concentrations associated with advancing age, higher body mass index, longer duration of diabetes, worsening glycemic control, and increased disease severity, particularly in advanced diabetic nephropathy stages (DN2 and DN3). Females generally exhibited higher uromodulin levels compared to males. Novelty: This study provides integrated evidence linking multiple demographic and metabolic determinants with uromodulin variation across different stages of diabetic kidney disease. Implications: The findings suggest that reduced uromodulin levels may serve as a biomarker for disease progression and risk stratification, supporting its potential utility in clinical monitoring and early identification of high-risk patients with type 2 diabetes mellitus. Highlights:• Uromodulin levels decline progressively across advanced diabetic nephropathy stages• Demographic and metabolic factors show significant associations with biomarker variation• Lower concentrations observed in prolonged disease duration and poor glycemic status Keywords: Uromodulin, Type 2 Diabetes Mellitus, Diabetic Kidney Disease, Glycemic Control, Body Mass Index
Determining the Levels of Zinc, Iron, Vitamin D, Renin Hormone, and Cystatin in Patients With Kidney Failure Abdalrahim H. Eefan
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.434

Abstract

General Background: Kidney failure is characterized by impaired filtration function requiring dialysis and associated with metabolic and biochemical disturbances. Specific Background: This study evaluated zinc, iron, vitamin D, renin hormone, and cystatin C levels among 100 kidney failure patients treated at a dialysis center in Mosul between March and May 2025. Knowledge Gap: Conventional indicators of renal dysfunction lack sufficient sensitivity, necessitating integrated biochemical profiling to better characterize disease status. Aims: To determine variations in selected trace elements, hormones, and proteins and their association with demographic and clinical factors in kidney failure patients. Results: The findings revealed decreased zinc, iron, vitamin D, and renin levels alongside elevated cystatin C concentrations, particularly in the 50–60 age group. Iron deficiency was linked to dialysis-related blood loss, while zinc deficiency was associated with malnutrition or independent occurrence. Vitamin D deficiency was associated with fluid imbalance and renal dysfunction, though not directly linked to renin deficiency. Higher disease prevalence was observed among smokers, rural residents, individuals with low education levels, and those consuming unsafe water sources. Novelty: The study integrates multiple biochemical markers with demographic variables, highlighting cystatin C as a sensitive indicator of glomerular insufficiency compared with traditional measures. Implications: These results support routine monitoring of trace elements, vitamin D, renin activity, and cystatin C to improve early detection and guide clinical and public health strategies in kidney failure management. Highlights:• Reduced Trace Elements and Hormone Levels Accompanied by Elevated Cystatin Protein• Higher Disease Occurrence Linked to Age Group 50–60 and Lifestyle Factors• Cystatin Biomarker Identifies Glomerular Dysfunction More Sensitively Than Conventional Measures Keywords: Kidney Failure, Zinc, Iron, Vitamin D, Cystatin C

Page 30 of 32 | Total Record : 311

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