cover
Contact Name
Juvita Herdianty
Contact Email
j.herdianty@gmail.com
Phone
085236539600
Journal Mail Official
sjpstrada@gmail.com
Editorial Address
Jl. Manila No.37, Tosaren, Kec. Pesantren, Kota Kediri, Jawa Timur 64123, Indonesia.
Location
Unknown,
Unknown
INDONESIA
Strada Journal of Pharmacy
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Articles 6 Documents
Search results for , issue "Vol. 2 No. 1 (2020): April" : 6 Documents clear
Formulation of capsule preparations with variations in aerosil concentration on the results of preparation evaluation Arif Wijayanto; Juvita Herdianty
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.132

Abstract

Capsules can be defined as a solid dosage form, where one or more types of drugs and/or other inert ingredients are contained in a shell or small container that can dissolve in water (Ansel 2005). Gelatin is a suitable material for making capsule shells because it is edible and soluble, forms a strong, thin-layered shell and changes from solution to gel form slightly above ambient temperature. Gelatin immediately dissolves in water at body temperature and does not dissolve if the temperature drops below 30°C (Agoes, 2008). Based on the test results, the disintegration time for F1 capsules is 2.12 minutes; F2 is 2.21 minutes; and F3, namely 2.27 minutes. These three formulas meet the requirements, namely not less or equal to 15 minutes. Based on the test results, F1 3.44 seconds, F2 3.76 seconds, F3 3.24 seconds, the flow speed of these three formulas meets the flow speed requirements, namely flow speed ≥ 10 g/second. The flow speed of the three formulas is in the good category, namely 2-10 g/sec which is said to be very good while it is said to be good. The flow speed is good because Aerosil has a very small and fine particle size. Apart from being an absorbent, aerosols are also able to improve flow properties by reducing friction between particles and by averaging test results from angles of repose F1 45°, F2 43° and F3 53°. In the weight uniformity test at F 1,2,3 it does not meet the requirements for factors that influence weight uniformity, namely lack of accuracy, different drug weights due to uneven distribution.
Rationality of Use of Analgetic-Antipyretic Medicines in Northern Region Primary Health Centre of Kediri City Hanie Kusuma Wardani; Krisogonus Ephrino Seran; Elisa Nur Farida
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.133

Abstract

One of the efforts carried out by the national rational drug use program is health services that ensure safety, effectiveness, and affordable costs for people who receive or receive treatment. It is said that the use of drugs is rational if the patient gets treatment according to clinical needs, the dose is as needed, the drug can be used for a sufficient period of time and at affordable costs. This study aims to determine the rationality of the use of analgesic-antipyretic drugs in the Northern Region Primary Health Centre of Kediri City which includes: right indication, right patient, right drug, right dose, and alert for drug side effects. This study is a descriptive study conducted by retrospective observation and data collection by looking at prescriptions and medical record data supported by interviews with pharmacists. Based on the results of the research in the Northern Region Primary Health Centre of Kediri City, it can be found that the use of analgesic-antipyretic drugs in 304 samples was obtained paracetamol 33.88%, paracetamol liquid 18.42%, Alpara 10.20%, ibuprofen 12.17%, acid mefenamic 8.88%, diclofenac sodium 7.24%, piroxicam 4.93%, and aspirin 4.28%. The percentage of rationality of using analgesic-antipyretic drugs in the Northern Region Primary Health Centre of Kediri City, got the results, namely: right indication, right patient, right drug, right dose, and alert for drug side effects by 100%.
Formulation of Wangi Pandan Leaves (Pandanus Amaryllifolius Roxb) to smooth, moisturize and repair the skin Juvita Herdianty; Alfara Derista Felany
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.134

Abstract

Bodyscrub is one of the products that is the result of rapid technological developments today, bodyscrub scrubs are used to maintain the cleanliness and freshness of body skin, bodyscrub products vary greatly starting from price, packaging color, softness of texture and aroma (Nina Hairiyah, Nuryati, and Fitri Nordiyah, 2022).The aim of using a body scrub is to remove dead skin cells, dirt and open pores so that the skin becomes brighter and whiter. Currently, there are many types of body scrubs circulating in society with various benefits ranging from smoothing the skin to whitening the skin (Hairiyah, N., & Nuryati, 2020) Medicinal plants have traditionally been used to treat many diseases and maintain health in Southeast Asia, many plants are described as having traditional medicinal properties. One of the plants that can be used in cosmetics is fragrant pandan leaves (pandanus amaryllifolius roxb) which is a tropical plant from the pandanaceae family. Pandan leaves can also be called pine leaves. because it resembles a pineapple with long, spiral green leaves. narrow and rope-shaped. Pandan leaves contain phytochemical compounds such as steroids, carbohydrates, phenols, flavones, alkaloids, glycosides, amino acids and many vitamins. The appearance and function of the skin is maintained by an important balance between water. This study aims to formulate and evaluate the physical quality results of pandan wangi leaves powder body scrub cream with emulgator concentrations of 15%, 14% and 13% stearic acid, and 1%, 2% and 3% triethanolamine. Experimental research method to determine variations in the concentration of stearic acid and triethanolamine emulsifiers. Observation of the results of evaluating the physical quality of the preparation includes organoleptic tests, homogeneity, pH, stickiness tests, spreadability tests and emulsion type. The result It can be concluded that the fragrant pandan leaf powder body scrub preparation can moisturize the skin, shows a homogeneous scrub with a semi-solid shape, is light green in color and has a typical pandan smell, has a neutral pH of 7.4 and 7.2 on day 7, the pH value is not appropriate The desired number is 6, this is because the preparation is influenced by the number of emulsifiers used. The more stearic acid, the lower the pH because of the large number of acid groups contained in stearic acid, while the more triethanolamine will cause the pH to be high due to the presence of basic groups contained in triethanolamine. with a spreadability of 5.1 cm and 4.83 cm on day 7. This is because the emulsifier concentration is high and the surfactant concentration is low, so the viscosity is very high so the spreadability is low. and the results of adhesion were 88.33 seconds and 49.33 seconds on day 7, adhesion was influenced by the viscosity of the base. Stickiness is closely related to viscosity.
TESTING THE ACTIVITY OF THE N-HEXANE FRACTION OF THE ETHANOL EXTRACT OF BETTER BETTER LEAVES (Momordica Charantia L.) WITH VASELINE CARRIER ON THE HEALING OF CUT WOUNDS IN WHITE RATS (Rattus Norvegicus) Lucky Andriani; Ivan Junius Mesak
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.135

Abstract

Wound are a form of damage to anatomical structure and function. When a wound occurs, the integrity of the epithelial structure of the skin is lost and dysfungtion occours in the skin. Therefore, normalization of integrity is required as soon as possible. Bitter melon leaves have benefits for wound healingand repairing skin granulation tissue. to understand the most optimal concentration level of N-Hexane Fraction of Bitter melon leaf ethanol extract in healing white rat incision wound using vaselin carrier and to understand the healing activity of N-Hexane fraction of Bitter melon leaf extract on white rat incision wound healing. The research conducted was an experimental type with the test animal, namely 18 white male rats. The white rats were grouped into 6 groups, where the standard control was group I, the positive control was group II with (injuring and giving sagestam cream) treatment, the negative control was group III with (injuring and giving it vaseline base) treatment, the last group IV, V, and VI were treated (injuring and giving it n-hexane fraction of bitter melon leaves at concentration levels of 1,5%, 3%, 6% and the base was vaseline).Then induced an incisions wound 2.0 cm deep and 0.2 cm long, but before shaving the rat’s back first and then anesthetizing using lidocaine injection. The observation process is carried out for 2 weeks and data collection is every 2 days. Furthermore, conduct statistical test when the data has been collected. Based on the results of observations and testing of the N-hexane fraction of bitter melon leaf ethanolextract, it has activity in healing cuts in white rats and the most optimal concentration in healing cuts is a concentration of 6%. The N-Hexane fraction of ethanol extract of bitter gourd leaves has activity in healing cuts in white rats and the most optimal concentration in healing cuts is 6%.
FORMULATION AND EVALUATION OF METAMIZOLE Na TABLETS WITH DIFFERENT CONCENTRATIONS OF SWEET POTATO FLOUR (Ipomea Batatas L.) AS DISINTEGRATOR Rizka Dianti Wahyudi; arif wijayanto
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.136

Abstract

Sweet potatoes have a fairly high starch content, namely 84.89%. High levels of starch can be used as a disintegrating agent in the manufacture of pharmaceutical preparations, namely tablets. The aim of this research is to determine the effect of variations in the concentration of sweet potato flour as a disintegrating agent and to determine how sweet potato flour is a candidate disintegrating agent in making tablet preparations using experimental methods in several concentrations on the properties and physical properties of Metamizole Na® tablets. Based on the results of this research, 3 formulations were made, namely formulation I (2.5%), formulation II (5%), formulation III (7.5%). The results obtained from this research indicate that formulation I is the best formulation of the other 3 formulas because formulation I is the formulation whose results in each test are closest to the positive control.
Antibacterial Activity Test of Ethanol Extract of Spoon Leaves (Plantago major. L) Against Pseudomonas aeruginosa Ira Jayani
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.153

Abstract

Typhoid is a bacterial infection disease of Pseudomonas aeruginosa. The irrationality of antibiotics against Pseudomonas aeruginosa is reported to trigger bacterial resistance, thus requiring an alternative antibacterial agent against typhoid. The diversity of Indonesian medicinal plants is still promising as a potential source of antibacterial agent, including sendok leaf. This study was aimed to determine antibacterial activity of ethanol extract of kacapiring leaves and its fractions against Pseudomonas aeruginosa. Subsequent fractionation was carried out using liquid-liquid partition method to obtain n-hexane, ethyl acetate, and etanol-water fractions. Antibacterial test was carried out using disk diffusion method to determine the diameter of inhibitory zone at concentrations of 10%, 15%, 20%, and 25%. The best antibacterial activity was revealed by residue fraction of 25% with inhibition zone diameter of 9,5 mm, respectively. Sendok have moderate antibacterial activity against Pseudomonas aeruginosa.

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