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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
 1 
Search results for , issue "Vol. 4 No. 2 (2022): October" : 6 Documents clear
The Effect of Solvent Variation on Flavonoid Content of Purslane Herb (Portulaca grandiflora Hook.) Indriasari, Christina
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.64

Abstract

Purslane is from the Portulaceae family which contains active phenolic compounds and has different antioxidant activities. Portulaca grandiflora Hook. is one of the species of purslane where all parts of the plant are useful. Purslane herb (Portulaca grandiflora Hook.) contains active compounds of alkaloids, flavonoids, tannins, terpenoids, and saponins. Flavonoids act as antioxidants. This study aims to determine the differences in flavonoid levels of extracts resulting from soxhletation of purslane (Portulaca grandiflora) herb with different solvents. This research is an experimental study with soxhletation extraction process and assay using a UV-Vis spectrophotometer with various concentrations of 5, 10, 15, 20, 25, and 30 ppm at a wavelength of 424.5nm. The flavonoid content in each extract of n-hexane, ethyl acetate, and 96% ethanol was 17.91% w/w; 23.27% w/w; 11.67% w/w.
Lip Cream Formulation With Natural Dyes From Secang Wood Leather Luluk Aniqoh Meliana; Juvita Herdianty; Arif Wijayanto
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.65

Abstract

Colorants are an important part of decorative cosmetics, including in lip cream preparations. Secang bark (Caesalpinia Sappan) contains chemical compounds of flavonoids, polyphenols, tannins and essential oils. Researchers formulate lip cream preparations by utilizing natural pigments contained in the bark of secang wood. The preparations were made with various concentrations of sappan bark extract, namely 15%, 20%, and 25%. Evaluation of the preparations made is an evaluation of physical quality including organoleptic tests, homogeneity, pH, spreadability, adhesion, smearing power, photostability, and stability tests by centrifugation method. Evaluation of safety was carried out through irritation test with patch test method and preference test. The results of the evaluation of lip cream preparations showed that all formulas had good greasing power and homogeneity, were physically stable which was characterized by no separation, and had good dispersibility, spreadability, and stable pH value. All preparations during storage for 21 days did not show changes in texture and odor. Then in terms of color, both organoleptically and photostability testing did not show a decrease in color intensity. Based on respondents' responses, the most preferred formula is formula II with the addition of an extract of 20%.
Antibacterial Test of Liquid Soap Preparations Rambutan Peel Extract (Nephelium lappaceum Linn) the Growth of Staphylococcus Aureus Juvita Herdianty; Luluk Aniqoh Meliana Putri; Arif Wijayanto
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.66

Abstract

Long-term use of antibiotics leads to resistance. Rambutan fruit is a fruit which grows seasonally, but the utilization of the fruit skin is still lacking. Several studies have been carried out but limited to the flesh and leaves. The purpose of this study was to utilize rambutan peel waste into a liquid soap preparation and then carry out an antibacterial test against Staphylococcus aureus bacteria. The content of compounds from the skin of rambutan fruit (Nephelium lappaceium Linn) is thought to have antibacterial properties. The content test was carried out using a phytochemical screening method. The screening results of rambutan peel extract showed the presence of alkaloids, flavonoids, saponins, and tannins. The antibacterial test method used the well diffusion method with concentrations of 20% 40%, 60% positive control of Biore liquid soap and negative control of soap base. The test parameters for liquid soap preparations include: organoleptic test, homogeneity test, pH test, foam height. The results showed the best concentration of 60% had the ability as an antibacterial against Staphylococcus aureus.
Test The Wound Healing Activity Of Nephelium Lappaceium Fructus Cortex Extract Ointment On New Zealand Rabbits Arif Wijayanto; Luluk Aniqoh Meliana Putri; Juvita Herdianty
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.67

Abstract

Nephelium lappaceium Linn.(Rambutan) is a natural ingredient rich in active substances that are beneficial to human health. In this study, the use of Nephelium lappaceium fructus cortex was used for the healing of open wounds where Nephelium lappaceium fructus cortex contains tannins which are expected to help heal open wounds. The content test was carried out using the phytochemical screening method of Nephelium lappaceium fructus cortex extract which showed the presence of alkaloids, flavonoids, saponins, and tannins, then a wound healing test was carried out with Nephelium lappaceium fructus cortex extract which was divided into 5 groups randomly, namely normal, negative control (Vaseline album) , positive control (Betadine salp® each gram contains 10% Povidone Iodine), presented topically 7.5% and 15% Nephelium lappaceium fructus cortex extract ointment. The back skin of New Zealand rabbits is 3-5 months old, weighs 1500–2000grams, has normal and healthy activities and has agile activities, is normal and in healthy condition, then was injured with a punch biopsy with a diameter of 5 mm, a depth of ± 0.5 mm, then treatment according to the test group for 21 days. Parameters measured included wound diameter in rabbits. The results showed that the ointment extract of Nephelium lappaceium fructus cortex 15% had an open wound healing activity which was comparable to a positive control with an open wound healing activity of 0.2mm.
Rationality of Use of Antibiotic at North Region City Primary Health Care Centre in Kediri City Hanie Kusuma Wardani; Krisogonus Ephrino Seran; Yogi Bhakti Marhenta; Febriarmayenri
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.68

Abstract

The implementation of health services by ensuring safety, effectiveness, and affordable costs for people who receive treatment is one of the efforts carried out by the Rational Drug Use program. It is said that the use of drugs is rational if the patient gets treatment according to clinical needs, the dose is as needed, the drug can be used for a sufficient period of time and at an affordable cost. This study aims to determine the rationality of the use of antibiotic drugs at North Region City Primary Health Care Centre in Kediri City with the indicators of Right Indication, Right Patient, Right Drug, Right Dosage, and Beware of Drug Side Effects. This study is a descriptive study with retrospective data collection by looking at prescriptions and medical records of patients using antibiotics and supported by open interviews with pharmacists. Based on the results of the study showed that the use of antibiotics in 273 samples obtained Penicillin class antibiotics was 46.89%, Other Antibiotics of 26.01%, Antituberculosis of 8.42%, Quinolones at 11.72%, Aminoglycosides of 5.13%, Tetracyclines of 1.10%, and Macrolides of 0.73%. The percentage of rationality for the use of antibiotic drugs which includes indicators of Right Indication, Right Patient, Right Drug, Right Dosage, and Alert for Drug Side Effects is 96%.
Analysis of Free Fatty Acid Contents (As Acid Laurat) Pure Coconut Oil (Virgin Coconut Oil /VCO) which Circulates in Kediri City Sri Rahayu Dwi Purnaningtyas
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.167

Abstract

Pure Coconut Oil (Virgin Coconut Oil / VCO) is a vegetable oil that contains medium chain saturated fatty acids. The medium-chain saturated fatty acid that has the highest content in virgin coconut oil is lauric acid. Lauric acid can be directly absorbed by the liver and used as an energy source. This study aims to determine the levels of free fatty acids (as lauric acid) in virgin coconut oil (Virgin Coconut Oil/VCO) according to SNI Standard 7381: 2008. The samples used in this study were pure coconut oil from various brands on the market in Indonesia. Kediri city. This study used an alkalimetry method to identify the free fatty acid levels in the sample. From the results of the analysis on 5 (five) brands of virgin coconut oil, it was found that all samples met the requirements of SNI 7381: 2008 which is a maximum of 0.2%. The results of the analysis of the levels of free fatty acids as lauric acid, the largest 0.1988% and the smallest 0.1643% according to the requirements of SNI.

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