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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
 1 
Search results for , issue "Vol. 6 No. 2 (2024): October" : 6 Documents clear
Anti-Typhoid Activity Test Of Cacao Leaf Fraction (Theobroma Cacao L.) Against Salmonella Typhi Bacteria In Vitro Dyah Ayu Rara Anggraini; Arif Wijayanto
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.145

Abstract

Introduction : Cocoa leaves (Theobroma cacao L.) are known to contain compounds with potential antibacterial properties. This study aims to investigate the antibacterial activity of various cocoa leaf fractions against Salmonella typhi. Methods: This experimental study involved the extraction of cocoa leaves followed by fractionation using polar, semi-polar, and non-polar solvents. The antibacterial activity was tested using the agar diffusion method to measure the inhibition zones produced by each fraction against Salmonella typhi. The positive control group used chloramphenicol at a concentration of 400 ppm, while the cocoa leaf fractions were tested at various concentrations. An ethanol-free test was also conducted to ensure no ethanol contamination in the fractions tested. Results: The results showed that the water, ethyl acetate, and n-hexane fractions of cocoa leaves exhibited significant antibacterial activity against Salmonella typhi. The water fraction at a concentration of 600 ppm showed the largest inhibition zone with a diameter of 27.30 mm, which is close to the effectiveness of the positive control chloramphenicol, which had an inhibition zone of 27.70 mm. The ethanol-free test confirmed that no ethanol was detected in the three fractions. Conclusion: Based on the data obtained, cocoa leaf fractions, especially the water fraction, have the potential to be effective natural antibacterial agents against Salmonella typhi. This finding provides a basis for further development in the use of cocoa leaf extracts as an alternative treatment for bacterial infections.
Analysis Of Compliance In Taking Anti-Tuberculosis Drug (Oat) On The Success Of Therapy In Drug-Sensitive Tuberculosis Patients At Muhammadiyah Ahmad Dahlan Hospital, Kediri City Gading Nurantika; Chintia Devientasari; Hanik Maria Dewi; Hanie Kusuma Wardani
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.146

Abstract

Tuberculosis, also known as "tubercle bacilli" (TB), is a directly transmissible disease caused by the Mycobacterium tuberculosis bacteria. Tuberculosis is a leading infectious disease that causes death worldwide. The WHO also identified the importance of achieving a high level of patient compliance in TB treatment to control the spread of this disease. This study aims to measure the extent to which tuberculosis patients at Muhammadiyah Ahmad Dahlan Hospital in Kediri City adhere to their treatment, thus achieving the success of OAT (Anti-Tuberculosis Drugs) therapy. The results of this study are expected to provide insights into the relationship between medication adherence and treatment success in drug-sensitive TB patients, as well as offer recommendations for improving patient compliance in TB treatment. The design of this study is quantitative, utilizing a retrospective cohort research design. The study population consists of all pulmonary tuberculosis (TB) patients who have undergone TB treatment for six months at Muhammadiyah Ahmad Dahlan Hospital in Kediri City, totaling 42 individuals. The sample was taken using a total population sampling method. Data analysis was conducted using cross-tabulation analysis with a chi-square test. The results of the study revealed that 18 patients (43%) had high adherence, 19 patients (45%) had moderate adherence, and 5 patients (12%) had low adherence. The majority of patients, 41 individuals (98%), were cured, while 1 patient (2%) was not cured. The chi-square test results showed a p-value of 0.023<0.005. The conclusion of this study is that there is a correlation between adherence to anti-tuberculosis (OAT) medication and the success of therapy. It is recommended that the hospital pays closer attention and provides motivation for patients to continue their treatment until full recovery.
Formulation And Evaluation Quality Physique Preparation Lip Tint Extract Sweet Potato ( Ipomoea batatas (L.) Lamb) with Extract Dragon Fruit ( Hylocereus polyrhizus ) As a Natural Lip Pigment Poppy Martha Lowra; Devita Riafinola Andaririt; Sri Rahayu Dwi P; Ivan Junius Mesak
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.147

Abstract

ABSTRACT Introduction: Lip Tint is one of the stock cosmetics that have role in give role decorative on lip pigment coloring . The rise of use dye synthesis in preparation dangerous liptint​ for lips so use material Sweet Potato Nature ( Ipomoea batatas) (L.) Lamb) which is combined Dragon Fruit ( Hylocereus polyrhizus ) can replace dye synthesis in the preparation. Purpose : to know difference concentration extract sweet potato jalar ( ipomoea Batatas (l.) lamb) combination extract fruit dragon ( hylocereus polyrhizus ) against evaluation quality physical . Method: research experimental formulation stock lip tint with using sweet potatoes concentrations of 10%, 20% and 30% combined fruit dragon 6%. Substance color natural contained in sweet potatoes are keratinoids and in fruit dragon that is anthocyanin . Results: In the study This show that stock lip tint sweet potato concentrations of 10, 20 and 30% combined fruit dragon 6%. Yield liptint that has texture , color , aroma, and Power stickiness , power spread , good viscosity . The pH of the preparation is at a value of 8 but No cause irritation to the skin . The results of the data analysis were obtained No there is significant difference in power test spread , power test adhesion and viscosity test and occurs significant differences in pH and FIII were most preferred by respondents . Conclusion: Research This own conclusion concentration sweet potato extract and extract fruit dragon influence results testing quality physique preparation . Quality test results physique show that stock lip tint with sweet potato concentration of 30% (F III) provides results best .
Antibacterial Activity Test of Combination of Chitosan and Ethanol Extract of Cocoa Leaves (Theobroma Cacao L.) Against Salmonella Typhi Bacteria Saifullah Al Fahmi; Luluk Aniqoh Meliana Putri; Ivan Junius Mesak; Juvita Herdianty
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.148

Abstract

Introduction:Typhoid fever is a systemic infectious disease caused by the bacterium Salmonella typhi. The increasing antibiotic resistance of Salmonella typhi has spurred interest in natural antibacterial agents. This study examines the antibacterial activity of a combination of chitosan and ethanol extract of cocoa leaves (Theobroma cacao L.) against Salmonella typhi. Methods: The research involved extracting cocoa leaves using ethanol and combining the extract with chitosan. The antibacterial activity was evaluated using the well diffusion method on Salmonella typhi. The combination of chitosan and cocoa leaf extract was tested at various concentrations, and chloramphenicol was used as a positive control. Results: The combination of chitosan and cocoa leaf extract showed significant antibacterial activity, with the best results obtained at higher concentrations. The zone of inhibition for the combination at 600 ppm was comparable to that of the positive control of chloramphenicol. Conclusion: The study suggests that the combination of chitosan and cocoa leaf extract has the potential to be developed as an alternative treatment for typhoid fever, particularly against antibiotic-resistant strains of Salmonella typhi.
Fomulation And Physical Quality Testing Of A Scrub Gel With Ethanol (70%) Extract Of Pineapple Core (Ananas comosus (L.) Merr.) Rizka Nursilah Ode; Juvita Herdianty; Sri Rahayu Dwi P.; Arif Wijayanto
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.150

Abstract

Scrubs are widely used in cosmetic care, primarily for exfoliation to remove dead skin cells. This study used a 70% ethanol extract from pineapple cores (Ananas comosus (L.) Merr.), which contains active compounds such as bromelain, flavonoids, and saponins. These compounds were formulated into a scrub gel that potentially benefits skin health, especially in exfoliation. The aim of this study was to evaluate good physical quality characteristics, including organoleptic properties, homogeneity, pH, viscosity, adhesion, and spreadability, based on varying concentrations of ethanol extract from pineapple cores. This research employed a true experimental method with a post-test only design to determine the best physical quality of scrub gel formulations containing pineapple core extract (Ananas comosus (L.) Merr.) at three extract concentrations: 3%, 5%, and 10%. The physical quality evaluation of the scrub gel, including organoleptic properties, homogeneity, viscosity, adhesion, and spreadability, showed good results and met the standards. However, the pH testing results for the three formulations did not meet the standards, as they were relatively neutral to slightly acidic (6.48-7.58). The hedonic test results indicated that Formulation 2 (5%) received the highest ratings in terms of aroma and texture, while Formulation 1 (3%) and Formulation 3 (10%) also showed a tendency to be preferred in certain aspects, particularly in terms of color and texture. The Kruskal-Wallis test followed by the Mann-Whitney test showed significant differences in pH, viscosity, and adhesion (p-value: 0.46-0.05 ≤ 0.05). Meanwhile, the One-Way ANOVA test on spreadability showed a very significant difference in spreadability, with Formulation 3 and the negative control having the highest spreadability (p-value <0.005). The concentration of pineapple core extract affects the physical and sensory characteristics of the scrub gel, with the addition of active pineapple core extract at a concentration starting from 3% already showing good physical characteristics.
Evaluation Of Fulfillment Of Pharmacy Service Standards In Clinical Pharmacy Services For Analgesic Drugs At Wijaya Pharmacy Health Of Kediri District Titis Surya A; Fidi Setyawan; Adi Wibisono; Chinthia Devientasari
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.161

Abstract

Pharmaceutical services are services related to pharmaceutical preparations such as drugs recommended for the treatment of improving the quality of life of patients. The government has made efforts to improve health services, including the construction of various health facilities such as pharmacies. In accordance with PMK Number 73 of 2016 concerning Standards of Clinical Pharmacy Services in Pharmacies, this study was conducted with the aim of determining the fulfillment of pharmaceutical service standards in clinical pharmacy services for analgesic drugs at the Wijaya Sehat Pharmacy, Kediri Regency, including clinical pharmacy services such as PIS, Counseling, DTM, and MDSE, along with the Attitudes and Behavior of pharmacists during service through patient or respondent perceptions. The research method uses a quantitative method with a cross-sectional research design, the tool used to conduct this study is a questionnaire using a Likert scale 1-4 (strongly agree, agree, disagree, strongly disagree). Sampling using accidental sampling technique of 120 respondents who purchased analgesic drugs. Instrument testing was conducted for validity and reliability in different places before conducting the study. The results obtained were that pharmaceutical services at Wijaya Sehat Pharmacy still carried out 2 services, namely PIS and Counseling, while DTM and MDSE had not been implemented due to limited human resources, there were no complaints related to Side Effects of Drugs (SED), there were no diseases that required DTM, and patients had a comfortable perception during service because pharmacists were polite and

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