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INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Health Professions
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,276 Documents
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Peran Suplementasi Vitamin D dalam Pencegahan Eksaserbasi Asma - Laporan Kasus Berbasis Bukti: Analisis Devina Sagitania
Cermin Dunia Kedokteran Vol 52 No 1 (2025): Obstetri & Ginekologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i1.1344

Abstract

Background: Asthma is a chronic inflammatory condition affecting the airways, marked by tissue changes and heightened bronchial sensitivity. Vitamin D, as an immunomodulator, may affect the inflammatory responses of the airways. Recent studies suggest that vitamin D supplementation has resulted in fewer exacerbations of asthma and improved lung function in both individuals with asthma and smokers. Other studies revealed a reduction of asthma exacerbations in corticosteroid-treated patients. This study sought to investigate whether vitamin D supplementation can decrease the frequency of asthma exacerbations. Methods: Literature research was done on three databases: PubMed, Cochrane Library, and ScienceDirect, related to the clinical question. Articles were chosen according to specific inclusion and exclusion criteria. All articles were critically appraised using the Oxford Center for Evidence-Based Medicine worksheet. Results: Three meta-analysis articles were critically appraised. The result is vitamin D supplementation can lower the incidence of asthma exacerbation, despite varying doses of vitamin D. Conclusion: Vitamin D supplementation was associated with a decrease in asthma exacerbations, despite varying doses of vitamin D. Vitamin D supplementation to corticosteroids can be considered potentially cost-effective and safe to prevent asthma exacerbations. Future studies should analyze the effect of vitamin D supplementation in long-term asthma therapy using the same dose.
Nefritis Lupus: Klasifikasi dan Tata Laksana Terkini: Tinjauan Pustaka Irianto; Willy Sunjaya; Jonathan Koswara
Cermin Dunia Kedokteran Vol 52 No 5 (2025): Kardiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i5.1346

Abstract

Lupus nephritis (LN) is one of the most common complications in systemic lupus erythematosus. If not detected quickly, LN will often cause reduced kidney function in five years necessitating kidney replacement. Diagnosis and classification of LN are made with a kidney biopsy. The drug of choice is based on the histopathology classification and needs to be tailored case by case. If complete remission is not achieved or if it relapses, the causes need to be investigated. More nephron cells can be saved in earlier therapy to prevent end stage kidney disease complications.
Diagnosis dan Tata Laksana Oftalmia Neonatorum: Tinjauan Pustaka Ria Marsela Suki
Cermin Dunia Kedokteran Vol 52 No 3 (2025): Oftalmologi dan Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i3.1362

Abstract

Ophthalmia neonatorum or neonatal conjunctivitis is an acute conjunctivitis in newborns under the age of 1 month. The causes are grouped into aseptic and septic types. Diagnosis is made by clinical symptoms and signs as well as laboratory examination. Appropriate treatment based on etiology can prevent permanent eye damage. Without optimal treatment, complications such as corneal ulceration, perforation, and even blindness may occur.
Manfaat Klinis Insulin Glargine U300 - Insulin Basal Generasi Kedua: Analisis Nanang Miftah
Cermin Dunia Kedokteran Vol 51 No 11 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i11.1363

Abstract

Untreated diabetes can lead to complications and increase the risk of death. Many patients with type 2 diabetes will require injectable medication within 5-10 years after diagnosis, following the failure of two or three oral antidiabetic therapies. Adding basal insulin can be well tolerated, more effective with lower risks of hypoglycemia and weight gain compared to other insulin regimens, but it carries a risk of hypoglycemia. Insulin glargine U300, with its special formulation, reduces the risk of hypoglycemia in diabetic patients.
Neoplasia Limfoid yang Menyerupai Mesotelioma: Laporan Kasus Irianto; Made Widya Wirayanti Puteri; I Wayan Sunaka; Novitasari
Cermin Dunia Kedokteran Vol 52 No 6 (2025): Kesehatan Jiwa
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i6.1366

Abstract

Pendahuluan : Neoplasma limfoid merupakan kelainan proses hematopoiesis lini limfoid, yang bisa mengarah ke limfoma ataupun leukemia. Mesotelioma merupakan pertumbuhan sel mesotel abnormal yang terkait kuat dengan paparan asbes. Pada gambaran radiologi, biasanya mesotelioma dideskripsikan sebagai lesi dengan densitas jaringan dengan batas yang tegas, spiculated yang menempel pada dinding toraks. Gambaran tersebut sebenarnya hanya menggambarkan suatu jaringan yang menempel pada toraks, dapat dicurigai mesotelioma, namun dapat juga akibat proses penyakit yang lain, seperti leukemia, limfoma, dan tuberkulosis. Kasus: Pria berusia 58 tahun datang ke IGD dengan keluhan sesak napas. Pasien awalnya dicurigai mesotelioma disertai kecurigaan keganasan darah, namun ternyata hasil biopsi lebih mengarah pada infiltrasi neoplasma limfoid. Simpulan: Pada pasien ini, neoplasma limfotik menginfiltrasi jaringan mesotel dan menghasilkan gambaran jaringan berbatas tegas dan spiculated yang menyerupai mesotelioma. Pemeriksaan biopsi sebagai baku emas belum dapat digantikan oleh pencitraan radiologi untuk saat ini, karena banyak proses penyakit lain yang dapat menyerupai suatu gambaran keganasan.
Kadar Fibrinogen Plasma sebagai Faktor Prognostik Karsinoma Hepatoseluler: Analisis Abdul Jafar Sidik; Wandy Ridayanto
Cermin Dunia Kedokteran Vol 52 No 2 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i2.1367

Abstract

Introduction: This article aims to determine the role of plasma fibrinogen level as a prognostic factor for hepatocellular carcinoma patients. Method: A structured literature review will be conducted through PubMed, Google Scholar, and ScienceDirect, according to the selected clinical questions. Literature selection was based on inclusion and exclusion criteria. The three selected literature were then critically appraised using criteria that included validity, importance, and applicability. Discussion: The three kinds of literature in this article all state that high plasma fibrinogen levels correlate with poor overall survival in hepatocellular carcinoma patients. Conclusion: Plasma fibrinogen levels may act as a prognostic factor for overall survival in hepatocellular carcinoma patients.
Sindrom Down: Skrining, Diagnosis, dan Konsekuensi Kesehatan: Tinjauan Pustaka Evita Zevanya
Cermin Dunia Kedokteran Vol 52 No 2 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i2.1368

Abstract

Sindrom Down merupakan penyakit bawaan atau kelainan genetik berupa kelebihan satu kromosom 21 yang menyebabkan berbagai manifestasi klinis dan gangguan kesehatan. Sindrom Down merupakan abnormalitas kromosom yang paling sering terdiagnosis. Kelainan ini menempati posisi teratas kecacatan sejak lahir di Indonesia. Abnormalitas kromosom menyebabkan anak sindrom Down lebih berisiko dan lebih sering mengalami berbagai gangguan kesehatan. Skrining dan kriteria yang tepat perlu dilakukan untuk menegakkan diagnosis.
Pengaruh Jumlah Kunjungan, Lama Tinggal (LOS), dan Kepadatan IGD terhadap Mortalitas di IGD RS Tersier Kota Malang: Hasil Penelitian Willy Johan; Rian Andriani; Kahar Mulyani
Cermin Dunia Kedokteran Vol 51 No 11 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i11.1378

Abstract

Introduction: Emergency department (ED) mortality is a critical issue that has a major impact on individuals, society, and the entire health system and is one of the indicators of emergency department service performance. This research aims to provide input to hospital management regarding the impact of non-medical factors (number of visits, length of stay/LOS, and ED crowding) on patient mortality, related to improvement policy-making in ED patient services. Method: A retrospective study on 130 ED shifts from medical record data during 2022-2023. The independent variables were the number of visits, LOS, ED crowding measured by CEDOCS, and ED mortality as the dependent variable. Results: There were deaths in 38 out of 130 shifts in the ED, with a total mortality of 1.6%. Statistical tests showed a significant effect between crowding and ED mortality (p = 0.01), a non-significant effect between visits and ED mortality (p = 0.76), and a non-significant effect between LOS and ED mortality (p = 0.62). The results of the regression analysis were able to explain the data (p = 0.91; Hosmer-Lameshow test). The area under the curve (AUC) for prognosis in hospital treatment is 0.641 with a 95% confidence interval of 0.539-0.744 (medium category). Conclusion: The significant effect between crowding and patient mortality in the ED indicates that strategic management must be carried out to reduce ED crowding.
Asparaginase untuk Terapi Leukemia Limfoblastik Akut pada Anak: Analisis Hastarita Lawrenti
Cermin Dunia Kedokteran Vol 52 No 3 (2025): Oftalmologi dan Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i3.1379

Abstract

Acute lymphoblastic leukemia (ALL) is the most frequently diagnosed childhood malignancy. The five-year survival rate in high-income countries is higher than in low-income countries. Asparaginase remains the cornerstone of treatment in childhood ALL. There are several types of asparaginase available worldwide, including native E. coli asparaginase, pegasparaginase, Erwinia asparaginase, calaspargase pegol, and recombinant Erwinia asparaginase. Hypersensitivity reactions are the main complication related to asparaginase. The other concern is the development of anti-asparaginase antibodies which results in silent inactivation with no therapy benefit. Therapeutic drug monitoring is required in pediatric patients with ALL undergoing asparaginase therapy.
Gangguan Sistem Penglihatan pada Pasien Pre-eklampsia/Eklampsia: Tinjauan Pustaka Maria Vania Tri Ekaputri
Cermin Dunia Kedokteran Vol 52 No 3 (2025): Oftalmologi dan Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i3.1383

Abstract

Pre-eklampsia dan eklampsia merupakan vaskulopati konstriktif yang dapat menyerang retina, pembuluh darah retina, hingga korteks serebri sistem penglihatan, yang dapat menyebabkan komplikasi gangguan penglihatan ringan hingga berat bahkan kebutaan. Gangguan penglihatan ini dapat dicegah dengan deteksi dini berkala atau pemeriksaan komprehensif untuk kasus yang lebih berat. Tata laksana yang tepat dan cepat dapat mengurangi risiko yang lebih berat hingga kecacatan permanen.

Page 97 of 128 | Total Record : 1276

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