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Journal of Medical Genetics and Clinical Biology (JMGCB)
Published by Antis Publisher
ISSN : -     EISSN : 30321085     DOI : https://doi.org/10.61796/jmgcB
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing
Journal of Medical Genetics and Clinical Biology is a peer-reviewed forum for advances at the intersection of human genetics and clinical medicine. The journal welcomes original research, reviews, brief reports, and case reports that translate genomic discoveries into clinical utility—spanning diagnostic workflows, risk stratification, therapeutic decision-making, and implementation in real-world care. Areas of interest include Mendelian and complex disorders, cancer genetics, pharmacogenomics, biomarkers, clinical genomics (panel testing, WES/WGS), bioinformatics and data integration, as well as ethical and counseling considerations. By bridging molecular insights and bedside applications, the journal aims to support precision health and improve outcomes across diverse patient populations.
Arjuna Subject : Imunologi dan Mikrobiologi (semua kategori) - Imunologi dan Mikrobiologi (Lain-Lain)
Articles 372 Documents
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Plasmids: Tiny pieces with high efficacy (Review) Kokaz, Osamah Faisal; Muhammad, Duaa abd Alabbas; Alkhuzaie, Mohammed Mudhafar
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 3 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i3.383

Abstract

Plasmids are of paramount importance in the field of bacterial ecology and evolution due to their facilitation of the horizontal transfer of accessory genes (HGT). It has become evident that, apart from their evolutionary role, plasmids also have the ability to influence the expression of various bacterial traits. Approximately 25% of the plasmids contain the necessary functions to autonomously undergo conjugation, while the remaining plasmids can be mobilized through conjugation at a later time. Given their potential significance, this review centers on the role of these minuscule sequences of nucleotides in various biological activities
An investigation of the correlation between flavonoids and cancer Hami, Hasan Jasim
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 3 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i3.384

Abstract

Antioxidant, anti-inflammatory, and anti-carcinogenic effects have been associated with flavonoids, a class of phenolic chemicals present in several plants. Brain, stomach, and blood cancers are just a few of the many types of malignancies that these substances have the potential to prevent or treat, according to research. Flavonoids have several effects on cancer, including slowing tumour development, promoting apoptosis, and preventing metastasis. Furthermore, their antioxidant capabilities can shield cells from free radical damage and lower cancer risk. To completely understand the effects of flavonoids and to define the exact quantities and methods of their administration for optimal efficacy, further study and more extensive clinical trials are needed, notwithstanding the early promising results. Nonetheless, a nutritious diet that includes foods high in flavonoids can aid in improving general health and lowering the risk of chronic illnesses
STUDY OF PREFRONTAL OXYGENATION DURING EMOTIONAL THINKING USING FUNCTIONAL NEAR-INFRARED SPECTROSCOPY (FNIRS) Kazem, Zaharaa Mohammed; Taleb, Ayat Hamid; Al-Hassan, Murtdha falah Abd; Hussein, Muqtada hussam; Naji, Noor hassan; Ali, Tuqa Ihsan Abd; Rahman, Mahir
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 4 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i4.385

Abstract

Introduction: This section provides an overview of the project and introduces the topic. It should include the background, objectives, and scope of the research. Literature Review: This section reviews relevant literature related to the topic to provide a better understanding of the existing research and technology available. It should include sources such as books, academic journals, and online articles. Methodology: This section outlines the methodology used to design and develop the project, including the hardware and software components, programming languages and tools used, and testing procedures. System Design: This section describes the architecture and design of the system, including the hardware and software components, communication protocols, and interfaces. It should provide a detailed explanation of how the system is structured. Implementation: This section details the process of implementing the system, including the setup of the hardware and software components, programming of the microcontroller and sensors, and integration of any external platforms. Results and Evaluation: This section presents the results of the testing and evaluation of the system, including the performance, efficiency, and effectiveness of the system in achieving its objectives. It should also discuss any limitations or challenges encountered during testing. Conclusion and Future Work: This section summarizes the research findings and provides recommendations for future work. It should discuss any potential for further development and improvement of the system.
Studying The Interaction of Laser with Human Tissue Rizvi, Noor Kareem
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 4 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i4.386

Abstract

A laser is amplified light beam to emit radiation. these rays are used in surgery by accurately projecting laser light to remove diseased tissue or bleed blood vessels by heating the target cells until they explode. The laser is used medically under objective or complete anesthesia. There are many types of lasers such as carbon dioxide laser, YAG laser, and argon beam, and each type of laser has a specific use, and each type of surgery and tissue has a special color of laser light. the uses of the laser in the surgery are multiple. brain and liver tumors can be removed while not to damage the healthy tissue surrounding the tumors. Lymphatic vessels can be closed to reduce the spread of tumor cells and nerve endings to reduce pain after surgery, small bleeding blood vessels can be closed, in addition to removing warts and skin tumors. A general advantage of laser surgery is the absence of bleeding, reduced surgical infections, pain and wound size, and a short hospital stay. The recovery period after laser treatment depends on the type of pathological condition and the patient's health condition before treatment. In the end: the laser has successful surgical uses to obtain good results with minimal complications, and contrary to what is common, its medical uses are specific to certain diseases and not for all types of surgery. In addition, laser treatment requires modern and complex devices and experienced experts in their use
THE ROLE OF PRIVATE CLINICS IN PUBLIC HEALTH CARE Uktamjonovna, Pulatova Lola
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 4 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i4.388

Abstract

In the course of reforms carried out in the years of independence in the field of health care, special attention was paid to the development of private sector activities along with state medical institutions. Strengthening all-round support for the development of the private sector in the health sector, creating the necessary conditions for private medical institutions to provide high-tech quality medical services to the population, expanding foreign investments, and attracting highly qualified specialists to the private medical sector, as well as medical tourism and to develop the export of medical services.
DETECTION OF OQXAB EFFLUX PUMPS GENE IN ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIA ISOLATED FROM PREGNANT WOMEN SUFFERED FROM URINARY TRACT INFECTIONS AND DIABETES MELLITUS IN BASRAH Nasir, Amna Ali; A.Al-Mousawi, Adnan; R. Abdul-Hussein, Zainab
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 4 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i4.394

Abstract

Considerably, pregnant women with diabetes mellitus are highly susceptible to urinary tract infections. The aim of the study is investigate the incidence of OqxAB efflux pumps gene among Escherichia coli and Klebsiella pneumonia isolates from urine of pregnant women suffered from urinary tract infections and Diabetes mellitus. E.coli and K.pneumonia were identified using conventional methods and confirmed by specific 16S rDNA primers. Antibiotic susceptibility test of E. coli and K. pneumonia isolates against several antibiotics were examined using Vitek®-2 compact system .The production of efflux pump by E. coli and K. pneumonia isolates were investigated phenotypically using ethidium bromide-agar cartwheel method (EtBr CW). Moreover, OqxAB Efflux Pumps genes were tested. The results showed that among 100 urine samples, 40 urine samples showed positive bacterial growth where 21(51%) E coli isolates, 8(20%) K. pneumonia isolates. In terms of antibiotic sensitivity, all E.coli and K.pneumonia isolates were resistant to ampicillin, piperacillin and ticarcillin, respectively. The prevalence of OqxAB efflux pump genes frequency ranges from 72% in E. coli and 50% in K. pneumonia.
THE ROLE OF PRIVATE CLINICS IN PUBLIC HEALTH CARE Uktamjonovna, Pulatova Lola
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 4 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i4.397

Abstract

In the course of reforms carried out in the years of independence in the field of health care, special attention was paid to the development of private sector activities along with state medical institutions. Strengthening all-round support for the development of the private sector in the health sector, creating the necessary conditions for private medical institutions to provide high-tech quality medical services to the population, expanding foreign investments, and attracting highly qualified specialists to the private medical sector, as well as medical tourism and to develop the export of medical services.
CONSEQUENCES OF LEADING HEALTH LIFESTYLE ON LIPID PROFILE Aziz, Nafi; Hussein, Saad; Farhood, Israa Kadhum; Aziz, Noor Nafi
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 4 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i4.401

Abstract

The activity of improving and promoting health is through leading proper health behavior which includes perfect and suitable methods for health living; through leading health lifestyle; via periodic medical consultations and attending physicians for medical checkup and advice. Beside choosing balanced diet and encourage sport exercises; cessation of smoking and alcohol intake. The other aspect, that results in promoting health, longevity and quality of living through preventing of disease occurrence should be through clinical and physical examination via screening services of diseases, such as ischemic heart disease, hypertension and renal problems. All these personal activities will lead to health lifestyle, which consequently is going to minimize the diseases might occur. On conclusion, the study shows that these behavioral aspects will reduce lipid profile; blood pressure, body weight and increase physical fitness in 42% of cases and border line effect on outcome is approximately about 58% of cases and the variable that plays a role is socio – economic status
A Novel Method of Extraction and Purification of Bacterial DNA for PCR Detection of MecA, 16SrRNA, VanB Abdullah, Raheem Hashim; Hassoni, Adil Abaed
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 4 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i4.403

Abstract

Bacteria are the main pest of nosocomial infections in healthcare facilities around the world. The aim of this study is to modify and minimize the amount of time, while still having no influence on the extraction's purity of DNA the method of extracting the DNA molecule and compare it with other methods that take longer to extract and purify DNA. This study examined two processes for isolating DNA from Gram-positive bacterial species: a boiling method and an enzymatic method that took one hour. In addition, the collected DNA was subjected to spectrophotometry, agarose gel electrophoresis, and PCR for both quantitative and qualitative examination. The results presented in this work show that boiling method pretreatment facilitates efficient cell lysis and DNA extraction, leading to increased yields of isolated bacterial DNA. In addition, DNA suitability for PCR-based identification of mecA,16SrRNA, VanB to Gram positive S. aureus strains was analyzed. Our findings demonstrated that the DNA generated by this simple approach is low-cost, quick, and safe, and that the process may be utilized in PCR methods on a wide range of gram-positive and gram negative species, as well as in laboratories without the necessary materials, tools, or technology
THE KNOWLEDGE, ATTITUDES, AND PRACTICES OF LIVESTOCK DEALERS IN WASIT PROVINCE, IRAQ REGARDING ZOONOTIC INFECTIONS Shanjar, Ali Mazahem
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 4 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i4.404

Abstract

This study aims to determine the knowledge, attitudes, and practices about diseases transmitted to humans from animals. The sample of the study is 77 persons working as breeders, fatteners, and sellers of cows and sheep in the countryside of wasit, Iraq. Those people answered some sociodemographic questions in addition to another three kinds of questions (knowledge attitudes and practices), the level score of knowledge was calculated by giving one point to every question. Participants were 72, and their average age was 45 years. The respondents whom had previously been infected were %87.6% of the respondents, however, 58.6% did not know that they infected from a healthy animal. Only 12.6% of the respondents received training on animal husbandry. The participants who had agricultural education were 37.6% of the participants. Those who know un-boiled milk can transmitted diseases were %65 of the and 96% of whom used to consume un-boiled milk. In this study, the lifetime prevalence of contracting diseases from animals was found to be 5.6%. Wearing gloves 36.2% while only % 28 of the participants was wearing masks. Who did not use any personal protective equipment were %13. Using raw milk was common among those who did not know that raw milk would be infected (p = 0.02). The participants were well informed about the disease transmitted from animals but they had less knowledge that poultry was also a source of infection (P <0.001). Participants do not demonstrate simple personal protective behaviour. Zoonotic diseases can be effectively addressed through the practice of occupational pathology, regional protection, the necessity of using personal protective equipment, and participation in training, especially in how to use it.

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