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Academia Open
Published by Universitas Muhammadiyah Sidoarjo
ISSN : -     EISSN : 27147444     DOI : 10.21070/acopen.11.2026.12985
Core Subject : Health,
Medicine & Pharmacology Public Health
Academia Open is published by Universitas Muhammadiyah Sidoarjo published 2 (two) issues per year (June and December). This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. This journal aims is to provide a place for academics and practitioners to publish original research and review articles. The articles basically contains any topics research or review. Academia Open is available in online version. Language used in this journal is Indonesia or English.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 2,389 Documents
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Powerful Antibacterial for Wound Healing using Betel Leaf Extract: Antibakteri Ampuh untuk Penyembuhan Luka menggunakan Ekstrak Daun Sirih Hida Salmah Fajriati; Nurul Azizah
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8096

Abstract

This study investigates the antibacterial properties of betel leaf (Piper Betle L) extract on suture wound infections caused by Staphylococcus aureus. Using 25 Webster mice divided into five groups, the research compared the healing effects of 5%, 10%, and 15% betel leaf extract against a control group and a gentamicin antibiotic group over 8 days. Results, measured with the REEDA scale, indicated that the 15% extract was most effective, achieving optimal healing by the eighth day. These findings suggest that betel leaf extract, particularly at higher concentrations, could serve as a potent alternative to traditional antibiotics for treating bacterial wound infections. Highlights: 15% Extract Most Effective: Achieved complete healing by eighth day. Comparative Study: Betel leaf extract vs. control and gentamicin. Antibacterial Alternative: Potential for treating bacterial wound infections. Keywords: Betel leaf extract, Piper Betle L, wound infection, Staphylococcus aureus, antibacterial
Location, Quality, and Price Drive Home Purchases in Indonesia: Lokasi, Kualitas, dan Harga Mendorong Pembelian Rumah di Indonesia Muhammad Afif Syaifudin; Misti Hariasih; Dewi Komala Sari
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8107

Abstract

This study examines the influence of location, product quality, and price on purchasing decisions at Graha Candi Pratama housing in Indonesia. Despite extensive research on housing purchase decisions, the unique contributions of these factors at Graha Candi Pratama have not been thoroughly explored. A quantitative approach was employed, sampling 96 homeowners via questionnaires, with data analyzed using SPSS 25. Results indicate that favorable location, high product quality, and affordable pricing significantly impact consumer decisions. Developers are advised to consider modern trends, cultural habits, and continually improve design and amenities while maintaining affordable pricing to attract buyers. Highlight: Location Impact: Proximity to amenities and transport influences purchase decisions. Product Quality: High-quality construction and variety increase buyer satisfaction. Price Affordability: Competitive pricing enhances housing project attractiveness. Keywoard: Housing purchase decision, location, product quality, price, consumer behavior
Unveiling Firm Value Dynamics Amidst COVID-19: Mengungkap Dinamika Nilai Perusahaan di Tengah COVID-19 Endah Permatasari; Eny Maryanti
Academia Open Vol. 9 No. 1 (2024): June
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8108

Abstract

This research investigates the impact of company size, leverage, company growth, and profitability on firm value in the food and beverage sector amidst the COVID-19 pandemic. Utilizing Partial Least Square regression and data from Indonesia Stock Exchange-listed companies, the study finds that company size, leverage, and profitability significantly influence firm value, while company growth does not. Moreover, company size affects profitability, while leverage and company growth do not notably impact profitability. Profitability serves as an intermediary between company size and firm value but does not mediate the relationship between leverage, company growth, and firm value. These findings highlight the importance of considering multiple factors concurrently in assessing firm value, particularly in times of crisis, offering valuable insights for managerial decision-making and policy formulation to enhance business resilience and sustainability. Highlights: 1. Analyzing firm value during COVID-19, emphasizing company size and profitability.2. Company size, leverage, and profitability significantly influence firm value.3. Profitability acts as a mediator, impacting firm value dynamics. Keywords: Firm value, COVID-19, Company factors, Profitability, Partial Least Square regression
Profitability's Critical Role in Shaping Capital Structure Dynamic: Peran Penting Profitabilitas dalam Membentuk Dinamika Struktur Modal Rizky Nur Wahyuningsih; Eny Maryanti
Academia Open Vol. 9 No. 1 (2024): June
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8110

Abstract

This study examines the impact of asset structure, liquidity, and sales growth on capital structure, with profitability as a moderating variable. Using data from Consumption Sector Manufacturing Companies listed on the IDX between 2018 and 2020, the research employs Partial Least Square (PLS) analysis on a sample of 16 qualified companies selected through Purposive Sampling. Results indicate that asset structure significantly influences capital structure, while liquidity and sales growth have no direct effect. Profitability moderates the relationship between liquidity and capital structure but does not moderate the impact of sales growth. This research contributes to understanding capital structure decisions in the Indonesian manufacturing sector, offering insights for financial managers and policymakers. Highlights: Asset structure drives capital decisions, leveraging debt for expansion. Profitability moderates liquidity's impact on capital structure. Insights aid financial managers in understanding manufacturing sector dynamics. Keywords: Capital structure, Asset structure, Liquidity, Profitability, Manufacturing sector
Emotion, Conformity, Aggression: Insights from Vocational High School Dynamics: Regulasi Emosi, Konformitas, dan Perilaku Agresif: Dinamika di SMK Muhammad Anwar Idris Al Mahsuny; Dwi Nastiti
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8113

Abstract

This quantitative correlational research investigates the impact of emotion regulation and peer conformity, both individually and concurrently, on aggressive behavior among students at Krembung Islamic Vocational High School. Utilizing a sample of 210 students from a population of 463, the study employed the emotion regulation scale, peer conformity scale, and aggression behavior scale. Multiple regression analysis with SPSS Ver.21 revealed significant results. Emotional regulation demonstrated a negative influence on aggressive behavior, while peer conformity exhibited a positive effect. Moreover, the combined impact of emotional regulation and peer conformity on aggressive behavior was established, with an overall influence of 20.7%. These findings contribute to the understanding of factors influencing aggressive behavior in the context of vocational high school students, emphasizing the importance of emotional regulation and peer dynamics. Highlights : Impact of Emotional Regulation and Peer Conformity: The study explores the individual and combined effects of emotion regulation and peer conformity on aggressive behavior among vocational high school students. Quantitative Correlational Research: Utilizing multiple regression analysis, the research employs a quantitative approach to understand the relationships between emotion regulation, peer conformity, and aggressive behavior. Practical Implications for Education: The findings provide insights for educational institutions in addressing and managing aggressive behavior by considering the roles of emotion regulation and peer conformity among students. Keywords: emotion regulation, peer conformity, aggressive behavior, vocational high school, quantitative correlational.
Circulating Microrna-146a as A Biomarker Related To Inflammation in Thalasemia Patients Heba Hani Hamzah; Nawal Khinteel Jabbar
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8120

Abstract

This study delves into the intricate realm of microRNAs (miRNAs), non-coding RNA molecules that wield significant influence in the pathogenesis of various disorders. With the advent of advanced technologies, accurate quantification of miRNA abundance across diverse tissues is now attainable. Notably, extracellular circulating microparticles have emerged as robust, stable indicators for blood-based disease diagnostics. This investigation explores the dynamic interplay between circulating microparticles and clinical phenotypes, offering valuable insights into disease intricacies. The research narrows its focus to recent developments in employing circulating microparticles as biomarkers for prevalent inflammatory disorders, including infections endemic to thalassemia patients in the city of Diwaniyah, Iraq. Current findings paint a promising future for the utilization of circulating microparticles in the management of inflammatory diseases. In conclusion, this comprehensive exploration of miRNA's regulatory role in globin gene expression has the potential to revolutionize the landscape of thalassemia, ameliorating clinical manifestations and symptoms of this debilitating hemoglobinopathy. The identification of miRNAs implicated in the disease's pathophysiology not only paves the way for novel diagnostic markers but also opens new horizons for therapeutic interventions. Highlights : MiRNA Significance: MicroRNAs play a pivotal role in the pathogenesis of various disorders, offering potential insights into disease mechanisms. Circulating Microparticles: Extracellular circulating microparticles are stable blood-based indicators, holding promise for disease diagnostics and management, especially in the context of inflammatory disorders. Thalassemia Insights: This study highlights the potential impact of miRNAs on globin gene expression, offering new avenues for the diagnosis and treatment of thalassemia, a debilitating hemoglobinopathy. Keywords : MicroRNAs (miRNAs), Circulating Microparticles, Thalassemia, Inflammatory Disorders, Disease Diagnostics
Novel Synthesis of Thiopyrimidine Compounds from Dibenzo-18-Crown-6 and Evaluation of Antibacterial Activity Zena Abdali; Raheem Jameel Mahesein
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8121

Abstract

In this study, we present a novel synthesis approach for the production of thiopyrimidine compounds, including P-OH-Thiopyrimidine, P-NO2-Thiopyrimidine, and P-Cl2-Thiopyrimidine, from the precursor compound dibenzo-18-crown-6 (DB-18-CE-6). These thiopyrimidine compounds have shown significant potential for various applications, particularly as antibacterial agents. The synthesis involved the reaction of DB-18-CE-6-derived alpha-beta unsaturated ketones with thiourea in a basic medium, resulting in successful cyclization. The synthesized thiopyrimidine compounds were evaluated for their antibacterial activity against common bacterial strains, including Streptococcus, Staphylococcus, and Proteus, and compared to the antibiotic Azithromycin. The results demonstrated that the thiopyrimidine compounds (Z, Z1, Z2, Z3) exhibited excellent antibacterial activity, surpassing Azithromycin, and highlighting their potential as effective alternatives to combat bacterial infections. This research opens new avenues for the development of antibacterial agents and emphasizes the significance of thiopyrimidine compounds in addressing bacterial resistance issues. Highlights : Novel synthesis of thiopyrimidine compounds from DB-18-CE-6. Evaluation of antibacterial activity against Streptococcus, Staphylococcus, and Proteus. Potential of thiopyrimidine compounds as effective antibacterial agents. Keywords : Thiopyrimidine compounds, Antibacterial activity, DB-18-CE-6, Novel synthesis, Bacterial resistance.
Financial Stability Drives Fraud in Indonesian Manufacturing: Stabilitas Keuangan Mendorong Penipuan di Sektor Manufaktur Indonesia Andini Nabila Firdaus; Heri Widodo
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8122

Abstract

This study investigates the influence of financial stability, external pressure, and financial targets on financial statement fraud in food and beverage manufacturing companies listed on the Indonesian Stock Exchange from 2017 to 2022. Using a quantitative approach with secondary data from 10 companies, we conducted multiple linear regression analysis with SPSS 26. Results indicate that financial stability significantly impacts financial statement fraud, while external pressure and financial targets do not. The findings suggest that improving financial stability can reduce financial statement fraud, highlighting the need for further research on the roles of external pressure and financial targets. Highlight: Financial Stability: Significantly impacts financial statement fraud. External Pressure: Does not significantly affect financial statement fraud. Financial Targets: No significant influence on financial statement fraud. Keywoard: Financial stability, external pressure, financial targets, financial statement fraud, Indonesian Stock Exchange
Social Media, Friendships, and Financial Literacy Drive Millennial Investments: Media Sosial, Pertemanan, dan Literasi Keuangan Mendorong Investasi Milenial Nesti Istichomah; Wisnu Panggah Setiyono
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8123

Abstract

This study explores the factors influencing millennial interest in investing, focusing on social media usage, investment understanding, and friendships. Using a quantitative approach, data was gathered from 100 respondents through questionnaires and analyzed with IBM SPSS 16. The results indicate that social media usage, investment knowledge, and friendships each significantly affect millennials' interest in investing, both individually and collectively. These findings highlight the pivotal role of digital platforms, financial literacy, and social networks in shaping investment behaviors among millennials. Highlight: Social media usage significantly influences millennials' investment interest. Investment understanding is crucial for millennials' investment decisions. Friendships play a key role in shaping millennial investment behaviors. Keywoard: Millennials, Investing, Social Media, Financial Literacy, Friendships
Exploring Hemingway's Depiction of War Violence: Psychological and Societal Impacts in Selected Novels Emad Mohammad Abbar
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8127

Abstract

This study delves into the portrayal of war violence in four seminal novels by Ernest Hemingway, namely, "A Farewell to Arms," "For Whom the Bell Tolls," "The Sun Also Rises," and "To Have and Have Not." Employing a qualitative analysis, this research categorizes instances of war violence based on thematic implications, narrative techniques, and character responses, while considering contextual information from Hemingway's own wartime experiences. The analysis unveils that Hemingway's exploration of war violence transcends the physical battlefield, emphasizing the profound psychological traumas, moral quandaries, and societal scars it inflicts. Characters within these narratives grapple with disillusionment, existential anguish, and a sense of alienation, reflecting the multifaceted impacts of war on individuals and society. Hemingway's personal involvement in World War I and the Spanish Civil War greatly influences his portrayal of war violence, presenting it as not only an external conflict but an internal struggle that challenges ideologies, identities, and human resilience. The thematic recurrence across these novels underscores Hemingway's persistent examination of the enduring consequences of war. In essence, Hemingway's depiction of war violence serves as a lens through which to contemplate the profound psychological and societal repercussions of conflict, offering an enduring reflection on the devastating nature of war. Highlights : Qualitative analysis of Hemingway's war narratives. Psychological and moral dilemmas in war literature. Hemingway's personal experiences and their literary influence. Keywords : War Violence, Hemingway Novels, Psychological Impacts, Societal Consequences, Qualitative Analysis

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