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International Journal of Biomedical Science and Travel Medicine
Published by Universitas Warmadewa
ISSN : 30477441     EISSN : 30477433     DOI : https://doi.org/10.22225/ijbstm
Core Subject : Health,
Medicine & Pharmacology Public Health
International Journal of Biomedical Science and Travel Medicine is published twice (March and September) a year. The objective is to promote articles on biology and medicine. International Journal of Biomedical Science and Travel Medicine publishes original research work related to biological and medicine. The journal publishes Original articles, Short Reports, Case Reports, and Review articles. All articles published in International Journal of Biomedical Science and Travel Medicine (IJBSTM) are peer-reviewed and published online for immediate access and citation. International Journal of Biomedical Science and Travel Medicine (IJBSTM) publishes the Original clinical and experimental research studies, Review articles, Case reports on topics but not limited to: Biocemistry, Genetics and molecular biology, Medicine, Environmental health, Tropical diseases, Diseases in tropics, Global health, Pharmacological sciences, Biomedical sciences, Public health, Infection, Epidemiology and clinical epidemiology, Molecular biology, Microbiology, Travel Medicine
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1 Documents
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Search results for , issue "45-49" : 1 Documents clear
Syndromic testing as a diagnostic modality for gastrointestinal infection Olivia Jocelyn; David Hutajulu; Erni Juwita Nelwan
International Journal of Biomedical Science and Travel Medicine 45-49
Publisher : Publication Department, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/ijbstm.1.2.2024.45-49

Abstract

Indonesia continues to grapple with sanitation issues, contributing to high incidence of gastrointestinal infections. Timely and accurate diagnosis is crucial to minimize the use of empirical antibiotics and medical expenses. Microbial culture, the current gold standard for diagnosing infections, has certain limitations in terms of duration and accuracy. There is a novel multiplex PCR (mPCR)-based diagnostic approach for infections called syndromic testing that can identify up to 20 pathogens simultaneously within 1–2 hours. This evidence-based case report aims to evaluate its sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) in diagnosing gastrointestinal infections. Literature search was conducted on February 21, 2024, across several databases which were PubMed, Scopus, Wiley Online Library, and ProQuest. Two prospective cross-sectional studies met the inclusion and exclusion criteria which were then critically appraised. Both studies measured the diagnostic accuracy of syndromic testing for Salmonella and Shigella, yielding sensitivity of 75–95.2%, specificity of >98%, PPV up to 88.2%, and NPV of >99%, indicating its good accuracy. Syndromic testing presents as a promising alternative diagnostic modality for infections, addressing the limitations of culture-based methods.

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