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Iyan Setiawan
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Jl. Sonokeling 1, no. B-30, Rt.002/Rw.008, Plamongan Indah, Plamongansari, Pedurungan, Semarang, Jawa Tengah
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INDONESIA
MURAKES
Published by CV. Muara Edukasi
ISSN : 31236405     EISSN : 3123562X     DOI : https://doi.org/10.64365
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Clinical Medicine & Specialties Public Health & Epidemiology Basic & Biomedical Sciences Nursing & Allied Health Professions Health Technology and Informatics Medical and Health Education
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Articles 37 Documents
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Karakterisasi Senyawa Metabolit Buah Duku (Lansium domesticum) Berdasarkan Studi Literatur serta Potensi Bioaktifnya dalam Bidang Kesehatan Evelyn Luna Anggraini; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.179

Abstract

Duku fruit (Lansium domesticum) is a tropical fruit that has potential as a natural source of metabolite compounds with various bioactive properties beneficial to human health. This study aimed to characterize the metabolite compounds present in duku fruit based on a literature review and to examine their bioactive potential in the health field. The research method employed was a literature study by reviewing relevant national and international scientific articles, particularly studies reporting the types of metabolite compounds, analytical methods used, and bioactive activities of duku fruit. The literature review results indicate that duku fruit contains various secondary metabolites, including flavonoids, phenolic compounds, terpenoids, alkaloids, and saponins, which have been identified using analytical methods such as phytochemical screening, chromatography, and spectroscopic techniques. These compounds have been reported to exhibit bioactive activities, including antioxidant, antibacterial, anti-inflammatory, and antidiabetic potentials. Based on the comparative analysis of the literature, duku fruit shows promising potential to be developed as a natural source for health-related applications. This review is expected to provide a scientific reference for further research on the utilization of duku fruit in the health sector
Eksplorasi Aktivitas Daun Pegangan (Centella Asiatica) dalam Mempercepat Proses Penyembuhan Luka Teuku Daffa Hasian; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.180

Abstract

Various therapeutic strategies have been developed to promote effective and safe wound healing, particularly those derived from natural sources. Centella asiatica has gained significant attention due to its bioactive compounds that support skin tissue regeneration. This paper aims to comprehensively review the biological activity and pharmacological mechanisms of Centella asiatica in the wound healing process. The study employed a qualitative descriptive method using a literature review approach, analyzing relevant national and international scientific publications. The findings indicate that major triterpenoid compounds, including asiaticoside, madecassoside, asiatic acid, and madecassic acid, play essential roles in stimulating fibroblast proliferation, enhancing collagen synthesis, accelerating epithelialization, and regulating inflammation and oxidative stress. In addition, the antibacterial properties and pigmentation-modulating effects of Centella asiatica contribute to improved wound healing quality. The use of modern topical formulations has been shown to increase bioavailability and therapeutic efficacy. In conclusion, Centella asiatica demonstrates strong potential as a safe, effective, and applicable natural-based therapeutic agent for wound management and dermatological application
Kajian Ilmiah Kelakai (Stenochlaena palustris) sebagai Tanaman Sumber Fitoestrogen untuk Optimalisasi Laktasi Atikah Nurul Fadhilah; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.185

Abstract

Kelakai (Stenochlaena palustris) is a fern plant traditionally used as food and medicinal plant. Recently, kelakai has gained scientific attention due to its bioactive compounds with potential phytoestrogenic activity, which mimic estrogen-like effects in the body. Phytoestrogens are known to play a role in lactation, particularly in supporting breast milk production. This study aims to review the scientific evidence regarding kelakai as a phytoestrogen source and its potential role in lactation optimization based on available literature. The method employed was a literature review of relevant national and international scientific articles related to kelakai, phytoestrogens, and lactation. The results indicate that kelakai contains secondary metabolites such as flavonoids and phenolic compounds that may contribute to phytoestrogenic activity. These compounds are reported to support hormonal balance and potentially enhance breast milk production. In conclusion, kelakai shows promise as a natural phytoestrogen source that may be developed to support lactation optimization and functional food applications.
Tinjauan Pustaka Senyawa Metabolit Bioaktif Daun Sambiloto (Andrographis paniculata) sebagai Agen Terapi Mirna Saputri Pratama; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.186

Abstract

Sambiloto (Andrographis paniculata) leaves are widely recognized as medicinal plants used in traditional therapy due to their rich content of bioactive secondary metabolites. Several bioactive compounds found in sambiloto leaves include andrographolide, flavonoids, phenolics, tannins, and alkaloids, which play important roles in therapeutic activities. One of the main issues is the lack of integrated reviews linking these bioactive metabolites with their potential use as therapeutic agents. This study aims to review the bioactive metabolite compounds of A. paniculata leaves and their roles in therapeutic applications. The method used was a literature review by analyzing various national and international scientific articles related to metabolite content and pharmacological activities of sambiloto leaves. The results indicate that phenolic compounds, flavonoids, and tannins contribute to antioxidant and anti-inflammatory activities, while andrographolide and alkaloids are associated with antimicrobial, antidiabetic, and immunomodulatory effects. In conclusion, sambiloto leaves have strong potential to be developed as natural therapeutic agents based on their bioactive secondary metabolites
Karakterisasi Senyawa Metabolit Sekunder Daun Kayu Putih (Melaleuca Leucadendra) Dan Potensi Bioaktivitasnya Dalam Bidang Farmasi Ni’matullathifah; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.187

Abstract

Eucalyptus (Melaleuca leucadendra) is a medicinal plant found abundantly in tropical Indonesia and is widely known as a source of essential oils with diverse pharmacological activities. Eucalyptus leaves contain various secondary metabolites, such as monoterpenes (especially 1,8-cineole), flavonoids, tannins, saponins, and phenolic compounds, which play a role in antibacterial, anti-inflammatory, antioxidant, and analgesic activities. This study aims to examine the characteristics of secondary metabolites in eucalyptus leaves and evaluate their potential bioactivity in the pharmaceutical field. The method used was a systematic literature review (SLR) of scientific publications from 2018–2025 that discussed the phytochemistry and pharmacological activities of Melaleuca leucadendra. The results indicate that the main constituent of eucalyptus leaf essential oil, particularly 1,8-cineole, has antimicrobial activity against Gram-positive and Gram-negative bacteria and acts as an anti-inflammatory agent by inhibiting inflammatory mediators. Furthermore, the flavonoid and phenolic compounds contribute to antioxidant activity, which is important in protecting cells from oxidative stress. These findings confirm that eucalyptus leaves have significant potential for development as a raw material for pharmaceutical preparations, both topical and inhaled
Review: Pemanfaatan Tape Kentan sebagai Sumber Energi Alternatif Berbasis Pangan Fermentasi untuk Beberapa Daerah di Indonesia Siti Dwi Cahira; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.197

Abstract

Indonesia’s dependence on fossil energy sources remains high, while their availability continues to decline and contributes to increasing carbon emissions and environmental degradation. This condition encourages the development of alternative energy sources that are renewable, environmentally friendly, and based on local potential. One underexplored potential is tape kentan, a traditional fermented food product produced through microbial activity capable of generating energy. Tape kentan contains simple carbohydrates resulting from the fermentation process that can potentially be converted into alternative energy, particularly bioethanol. This study aims to comprehensively review the utilization of tape kentan as an alternative energy source based on fermented food in several regions of Indonesia. The research method employed is a literature review, examining scientific sources such as national and international journals, research reports, and relevant publications discussing food fermentation and alternative energy. The results indicate that tape kentan has a relatively high reducing sugar content due to the activity of yeast and bacteria during fermentation, making it a potential raw material for bioenergy production. The utilization of tape kentan as an alternative energy source is considered suitable for rural areas with abundant local raw materials. These findings suggest that traditional fermented foods have not only consumption value but also strategic value in supporting energy security. In conclusion, tape kentan has the potential to be developed as a local wisdom-based alternative energy source with further research support and appropriate policies
Kajian Fitokimia dan Potensi Bioaktif Sayur Kelakai (Stenochlaena palustris) sebagai Sumber Serat dan Zat Besi untuk Kesehatan Leviona Dhina Safira; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.212

Abstract

Kelakai vegetable (Stenochlaena palustris) is a fern plant commonly consumed by communities living in wetland and swamp areas, particularly in Kalimantan. Traditionally, this plant has been used as a daily vegetable and is believed to provide health benefits, especially in improving blood quality and maintaining physical vitality. This study aims to review, based on literature sources, the phytochemical content and bioactive potential of kelakai as a source of dietary fiber and iron for health promotion. Various literature sources indicate that kelakai contains diverse phytochemical compounds, including flavonoids, phenolic compounds, alkaloids, and tannins, which exhibit potential antioxidant activity. The dietary fiber content in kelakai plays an important role in supporting digestive health, assisting in blood glucose regulation, and maintaining gut microbiota balance. In addition, kelakai is reported to have relatively high iron content compared to several other green vegetables, suggesting its potential role in preventing anemia, particularly iron deficiency anemia. The bioactive properties of kelakai also contribute to cellular protection against oxidative stress and support metabolic functions in the body. Based on this literature review, kelakai demonstrates significant potential as a local functional food with valuable nutritional and health benefits. Further development and utilization of kelakai are expected to support food diversification and contribute to improved public health outcomes
Karakterisasi Kandungan Gizi dan Potensi Bioaktif Bubur Kacang Hijau sebagai Pangan Tradisional Sumber Protein Nabati dan Energi Dia Elsa Putri; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.213

Abstract

Green bean porridge is one of Indonesia’s traditional foods widely consumed by various segments of society. This food is made from mung beans (Vigna radiata) cooked until soft and served with natural sweeteners such as sugar and coconut milk. In addition to being easily accessible and affordable, green bean porridge is known as a good source of plant-based protein and energy. This article aims to review the nutritional content, characteristics of bioactive compounds, and potential health benefits of green bean porridge based on a literature study. The method used was a literature review of scientific journals and other reliable sources. The results indicate that green bean porridge contains carbohydrates, protein, dietary fiber, vitamins, minerals, and phenolic compounds with potential antioxidant activity. Green bean porridge has the potential to be developed as a nutritious traditional food and a functional food based on natural ingredients
Kandungan Fitokimia Daun Duku Kumpeh dan Manfaatnya Bagi Kesehatan Dia Dian Novita; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.214

Abstract

Kumpeh duku leaves are part of a local duku plant that has traditionally been used by communities as a natural medicinal resource. Various literature sources indicate that Kumpeh duku leaves contain diverse phytochemical compounds that potentially provide health benefits. The phytochemical components commonly found in duku leaves include flavonoids, alkaloids, saponins, tannins, and phenolic compounds. These compounds are known to exhibit biological activities that support the maintenance of body functions. This literature review aims to examine the phytochemical content of Kumpeh duku leaves and their health benefits based on previous studies. The review results indicate that flavonoids and phenolic compounds in duku leaves act as antioxidants that help protect body cells from damage caused by free radicals. In addition, alkaloids and saponins are reported to possess antibacterial and anti-inflammatory activities that may inhibit the growth of pathogenic microorganisms and reduce inflammation. Kumpeh duku leaves are also suggested to support digestive health, enhance the immune system, and help regulate blood glucose levels. Based on the literature review, it can be concluded that Kumpeh duku leaves have significant potential as a natural source of phytochemical compounds beneficial to health. The proper utilization of Kumpeh duku leaves may be developed as an alternative herbal resource to support community health improvement
Kajian Sistematis Peran Senyawa Bioaktif Fenolik Daun Salam (Syzygium polyanthum) terhadap Aktivitas Kesehatan Rifky Rifaldo Munthe; Ardi Mustakim
MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan Vol. 2 No. 1 (2026): MUARA KESEHATAN : Jurnal Ilmiah Ilmu Kesehatan & Medis
Publisher : CV. Muara Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64365/murakes.v2i1.218

Abstract

Bay leaf (Syzygium polyanthum) is a herbal plant traditionally used as a culinary ingredient and natural medicine for maintaining health. The increasing use of natural products highlights the need for a systematic scientific review to evaluate the pharmacological potential of bay leaves based on their bioactive compounds, particularly phenolic compounds. This study aims to identify the presence of phenolic compounds in S. polyanthum leaves and analyze their association with pharmacological potential in the health sector. The method involved a systematic review of relevant national and international scientific literature, selection of articles based on inclusion and exclusion criteria, and descriptive analysis of selected studies. The identification of phenolic compounds in bay leaves was conducted using a qualitative ferric chloride (FeCl₃) 3% test as the primary method. The results indicate that bay leaves are positive for phenolic compounds, as evidenced by characteristic color changes in the FeCl₃ test. These compounds contribute to various pharmacological activities, including antioxidant, antidiabetic, anti-inflammatory, and antimicrobial effects. The findings suggest that S. polyanthum leaves have potential to be developed as functional natural ingredients and phytopharmaceutical candidates, although further studies on quantification and method standardization are required.

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