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International Journal of Integrated Health Sciences
Published by Universitas Padjadjaran
ISSN : 23021381     EISSN : 23384506     DOI : 10.15850/ijihs
Core Subject : Health,
Health Professions
International Journal of Integrated Health Sciences (IJIHS) is a peer-review journal which publishes original articles, medical research, clinical research and case report. This journal is supported by Faculty of Medicine Universitas Padjadjaran and was launched on September 22nd 2012 and firstly published on July 2013. The first and second publications in 2013 and 2014 were published annually. In 2015 IJIHS published twice in a year, March and September.
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Articles 10 Documents
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Search results for , issue "Vol 12, No 2 (2024)" : 10 Documents clear
Outcome of Minimally Invasive Percutaneous Plate Osteosynthesis Using Locking Compression Plate for Distal Tibial Fractures Rampure, Sagar; Choraria, Harsh; Hanchate, Krishna; Mahadik, Sujay K; Deshpande, Shrikant
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3991

Abstract

Objectives: To assess the functional and radiological outcomes of the distal tibia fractures managed surgically with a locking compression plate by MIPPO technique.Methods: This prospective observational study included 34 patients with distal tibial fractures treated at Bharati Vidyapeeth (Deemed to be University) Medical College and Hospital, Sangli, India. After ethics committee approval and informed consent, eligible adults with complex or unfavorable simple, closed fractures were enrolled. Exclusions were patients under 18 with pathological fractures or comorbidities affecting functional outcomes. Standard preoperative protocols and imaging were conducted. All patients were surgically managed with a locking compression plate by MIPPO technique. Postoperatively, exercises and staged weight-bearing were implemented. Follow-up assessments at 45, 90, 135, and 180 days evaluated pain, movement, and radiological union using Olerud and Molander score. Statistical analysis utilized paired t-test and Chi-Square test.Results: Out of 34 patients with distal tibial fractures, 24 (70.6%) were males and 10 (29.4%) were females with a mean age of 41.88 years. Most fractures were 42A1 (35.3%) and 43A2 (32.4%). Post-operative superficial wound infection occurred in 3 (8.8%) and deep infection in 2 (5.9%). Mean union time was 16.62 weeks. Functional outcomes were excellent in 3 (8.8%), good in 22 (64.7%), and fair in 9 (26.5%). At six months, complications included ankle stiffness (29.4%), non-union (20.6%), and malunion (8.8%). No cases had plate or screw breakage.Conclusion: MIPPO technique allows for good functional outcomes while reducing complications, especially in fractures with poor soft tissue conditions.
Differential White Blood Cell Count and COVID-19 Hospital Length of Stay: A Post-hoc Analysis Gustya, Gita Fajri; Nugraha, Darrin Ananda; Rakasiwi, Muhammad Ilham Dhiya; Azzumar, Farchan; Burhan, Erlina
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3915

Abstract

Objective: To explore the association between differential white blood cell count and hospital length of stay (LOS) in COVID-19 patients.Methods: This study is a post-hoc analysis of two prospective cohort studies involving hospitalized COVID-19 patients who received standard therapy, including antiviral and supportive treatments at Persahabatan Hospital, Jakarta, Indonesia, during the Delta and Omicron dominant pandemic periods. Baseline differential white blood cell count before initiation of therapy were documented. LOS was categorized as ≤10 days and >10 days.Result: Data from 463 subjects were included with most subjects were males (62.2%) with a median age of 54 (14–93) years. The average LOS for subjects was 12.7 (12.1–13.4) days. Bivariate tests showed that lymphocytes, neutrophils, monocytes, neutrophil-lymphocyte ratio (NLR), and neutrophil-monocyte ratio (NMR) had significant association (p <0.05) to LOS. Logistic regression showed that higher monocyte counts were associated with shorter LOS (adjusted OR 0.89; 95% CI 0.840 - 0.943; p < 0.001). ROC curve showed that higher monocyte counts (>8.35 × 10^3/µL) at admission may predict shorter hospitalization (<10 days).Conclusion: Monocyte count may serve as a potential marker for length of stay in COVID-19 patients, offering key insights for optimizing patient management and resource allocation.
Prevalence of Thyroid Function Abnormalities and Its Association with Physical Fatigue in First-Year Medical Students Ghosh, Arindam; Dasgupta, Debdeep; Biswas, Susumna
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.4087

Abstract

Objective: To estimate prevalence and type of thyroid function abnormalities and explore their associations with physical fatigue in first-year medical students.Methods: This was a cross-sectional observational study comprising of 200 first-year medical students.  Demographic details and history of any significant medical illness was asked and noted. Thyroid function tests were conducted on all participants. The prevalence and type of thyroid function abnormalities were documented in all students,  and the presence and severity of physical fatigue were assessed on the basis of physical fatigue score. Participants with any kind of thyroid function abnormality were compared with those with normal thyroid function tests for presence and severity of fatigue.Results: Among the 200 students, 144 (72%) were males and 56 (28%) were females, resulting in a male-to-female ratio of 1:0.38. Subclinical hypothyroidism was identified in 9% of students (18 cases), while clinical hypothyroidism was present in 7% (14 cases). Additionally, subclinical hyperthyroidism was detected in 1% of students (2 cases), with no cases of clinical hyperthyroidism reported. Female students were found to be having more thyroid function abnormalities as compared to male students and the difference was found to be statistically significant (p=0.0109).  Students with abnormal thyroid function tests (34 cases) had a markedly higher mean FSS score (43.22±4.50) as compared to students with euthyroid (16.85±2.70).Conclusion: Subclinical thyroid abnormalities are prevalent among young individuals, particularly those with physical fatigue. This study revealed a significant link between presence of fatigue and the possibility of thyroid dysfunction.
Ifosfamide-Induced Encephalopathy in Relapsed Lymphoma: Report of Two Cases Takaryanto, Davin; Harti, Gusti Fungani; Oehadian, Amaylia
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3558

Abstract

Objective: Ifosfamide is a chemotherapeutic drug available for various malignancy, including lymphoma. Ifosfamide has adverse effects including myelosuppression, nephrotoxicity, hemorrhagic cystitis, and neurotoxicity. Encephalopathy is a severe manifestation of neurotoxicity due to ifosfamide, with an incidence of 10–40%. This study aimed to report two cases of ifosfamide-induced encephalopathy.Case: This case studies reported two relapsed lymphoma patients with almost similar characteristics who received ifosfamide chemotherapy. The first case of 48-year-old woman with relapsed High-Grade B-cell lymphoma stage IIIBE while the second case of 38-year-old woman with relapsed non-hodgkin lymphoma. The first case showed a good outcome with improvement in consciousness 48 hours after stopping ifosfamide and thiamine, while the second case experienced tumor lysis syndrome, leading to the death of the patient.Conclusion: Mechanism of ifosfamide-induced encephalopathy remains unclear, with the hypothesis from the neurotoxic effects of the resultant metabolite chloracetyldehide. Radiology examination of the brain and electroencephalography is required to rule out other differential diagnoses. Early recognition of adverse effects, followed by immediate discontinuation of ifosfamide, administration of therapy, such as methylene blue and/or thiamine, and supportive treatment usually produced good outcomes.
Knowledge on and Compliance with Standard Precautions among Medical Students in Jharkhand, India: A Cross-Sectional Study Jawanpuria, Ankita; Dash, Chinmaya
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3711

Abstract

Objective: To assess the knowledge, attitude, and compliance with standard precautions among medical students in a tertiary care hospital in Jharkhand, India.Methods: A total of 280 medical students, including phase I and phase II MBBS students, participated in the study. Phase I comprised an introduction to standard precautions in four-hour classes while the Phase II comprised of 8 hours of theory and three skill assessments on standard precautions according to the CBME curriculum and pandemic module. A structured validated questionnaire was used to collect data on the student's knowledge, attitude, and practice related to standard precautions. The questionnaire included items assessing various aspects of standard precautions, and scoring criteria were used to evaluate student performance. The overall level of knowledge, attitude, and practice was classified as poor (<50% score), moderate (50–79% score), and good (≥80% score).Results: Among the phase I students, 32.8% got a good score. In contrast, in the phase II, 56.6% demonstrated good performance in adhering to standard precautions. The median total score was 68 (interquartile range 62-71) of 85, indicating a satisfactory level of understanding and compliance with standard precautions. However, areas such as needing to remove PPE before leaving the patient's environment and not recapping needles showed rooms for improvement.Conclusion: Students showed good knowledge and compliance with standard precautions. Phase II students demonstrated a better understanding of standard precautions compared to their phase I counterparts. This highlights the positive impact of practical hands-on training as particularly emphasized in the phase II curriculum.
Role of Ultrasound Imaging in Children with Dengue Fever: A Retrospective Study Sean Martin, Juliet Anitha; Annadurai, Karthikeyan
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.4100

Abstract

Objective: To study ultrasound findings of children with dengue and analyze the possible correlation between ultrasound findings  and severity of dengue in children.Methods: This retrospective study, which was conducted over one year, analyzed 50 pediatric dengue patients. Ultrasound findings such as gallbladder wall edema, pleural effusion and ascites were assessed. Cases were categorized into dengue without warning signs, dengue with warning signs, and severe dengue according to the World Health Organization's classification of dengue. Correlation between ultrasound abnormalities,  severity of dengue, and  thrombocytopenia were analyses. A p-value of less than 0.05 was taken as statistically significant.Results: Of 50 pediatric patients diagnosed with dengue participated in this study, 72% were boys, and 28% were girls with a male-to-female ratio of 1:0.38. Fever was the most frequent symptom (100%), followed by nausea/vomiting (84%) and body ache/myalgia (78%). Ultrasound findings revealed that gallbladder wall edema (48%), pleural effusion (44%), and ascites (50%) were significantly associated with severe dengue and dengue with warning signs (p<0.001). Thrombocytopenia was documented in 58% of cases and correlated significantly with ultrasound abnormalities such as gallbladder wall edema, ascites, and pleural effusion (p=0.0017).Conclusion: Ultrasound findings, such as gallbladder wall edema, pleural effusion and ascites, are significantly associated with severe dengue and dengue with warning signs. These features aid in early identification of high-risk patients.
Factors affecting Umbilical Cord Vitamin D Concentration and Its Association with Maternal Vitamin D Level Aggarwal, Aditya; Modi, Amit Kumar; Singh, K. Rimi; Jha, Avinash Kumar
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3963

Abstract

Objective: To analyze factors affecting maternal and umbilical cord levels of vitamin D and to understand the correlation between maternal and umbilical cord vitamin D levels.Methods: This was a cross-sectional study conducted at the department of pediatrics of Dr. D. Y. Patil Medical College and Research Centre, Pune, India. Maternal and umbilical cord vitamin D levels were examined in 300 pairs of mother and child over a period of two years. Informed consent was obtained from all participants. The vitamin D level was measured using chemiluminescent immunoassay and classified as either deficient, insufficient or adequate depending on specific cut-offs. Correlations between maternal and neonatal vitamin D levels and demographic factors like religion, socioeconomic status, and sun exposure were also exlored. Statistical tests were performed using the SPSS 21.0 software, with p<0.05 deemed P-valueas significant.Results: There was significantly high prevalence of vitamin D deficiency in neonates, (78.67%). Key factors influencing maternal vitamin D levels were religion (p=0.027), maternal education (p=0.003), gravida status (p=0.035), and sunlight exposure, with sunlight exposure showing a very strong correlation to the deficiency (p<0.001). Moreover, maternal serum calcium levels significantly affected vitamin D status (p<0.001). A significant association was observed between maternal and cord blood vitamin D levels, with the maternal vitamin D level strongly predicted vitamin D status in neonates (p<0.001).Conclusion: The umbilical cord vitamin D level strongly correlates with the maternal vitamin D level, which is  significantly affected by maternal education, residence, pregnancy status, gestational age, and sun exposure.
Nutrition Education Effect in Increasing Knowledge and Ability to Interpret Nutrition Facts in Adolescents Meylinda, Jovita Octa; Arinda, Ditia Fitri; Yuliana, Indah; Sari, Desri Maulina
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3564

Abstract

Objective: To evaluate the effectiveness of nutrition education on the understanding and proficiency in interpreting nutrition labels among adolescents aged 16-18 years..Methods: This quantitative study adopted quasi-experimental and control group designs with a pre-test and post-test approach. The sample size included 60 participants, divided into 2 equal groups, receiving education through lecture method and leaflets, respectively. The intertervention was conducted one day in group 1 and group 2, respectively. Sample selection was conducted using a simple random sampling method. Data were collected through a knowledge questionnaire and details on reading ability were obtained using an interpreting ability checklist through pre-tests and post-tests conducted at the same day. The retrieved data were analyzed using the Wilcoxon Signed Rank Test and the Mann-Whitney U Test (α=0.05).Results: Nutrition education is shown to enhance the understanding (p-value=0,026) and proficiency of students in interpreting nutrition facts (p-value=0,064).Conclusion: Nutrition education had a positive impact on the understanding and skill of adolescents in reading nutrition facts. Thus, developing educational materials that can be readily applied in daily life will help consumers in making more nutritionally informed choices when selecting packaged foods.
Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study Goyal, Lalit; Gupta, Saloni; Nagar, Sachin; Bhargava, Vinay
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3988

Abstract

Objective: To assess feasibility, safety, and efficacy of segmental spinal anesthesia with isobaric levobupivacaine in patients undergoing various abdominal and lower limb surgeries. Methods: This was a prospective cohort study conducted at the Department of Anesthesiology and Critical Care of Kota Heart Institute and group of hospitals in India. The study involved  100 patients undergoing various abdominal and lower limb surgeries under segmental spinal anesthesia (SSA). Isobaric levobupivacaine 0.5% with fentanyl 20-25 μg or dexmedetomidine 5-10 as adjuvant or  hypobaric levobupivacaine 0.167%  was injected in intervertebral space depending on the surgery. Hemodynamic parameters, postoperative pain level, and adverse effects were analyzed with a p-value less than 0.05 was considered statistically significant.Results: An overall male predominance was observed with a 1:0.515 male-to-female ratio. The most affected age group was 41-50 years (37%), with a mean age of 44.51 ± 11.72 years. ASA classification indicated 34% of patients in ASA I, 40% in ASA II, 24% ASA III and 2% in ASA IV . The primary surgery was laparoscopic cholecystectomy (26%) in normal risk group and orthopedic in high-risk group(20%). Postoperative pain assessment showed mean VAS scores ranging from 1.92 to 3.42 at different time intervals. Common adverse effects were hemodynamic instability (13%), shoulder tip pain (33%), PONV (3%), headache (6%), pruritis (2%) and urinary retention (1%). The hemodynamic instability showed less incidence in ASA III/IV category.Conclusion: Segmental spinal anesthesia can be used successfully for abdominal and lower limb orthopedic surgeries in patients of ASA I to ASA IV.
Tacrolimus Therapy Among Steroid-Resistant Nephrotic Syndrome Children: A Preliminary Study in West Java, Indonesia Widiasta, Ahmedz; Wahyudi, Kurnia; Rachmadi, Dedi
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3663

Abstract

Objective: To explore the outcomes of Tac therapy for Steroid-Resistant Nephrotic Syndrome (SRNS) and its implication in reducing the number of CKD events.Methods: An open, prospective, cohort study was conducted at a tertiary hospital in Bandung, West Java, Indonesia. Children (age 1–18 years old) with steroid and cyclophosphamide resistant nephrotic syndrome were enrolled in this study. Blood pressure, urinary protein, serum ureum, and creatinine levels were measured every month, Tac and soluble urokinase plasminogen activator receptor (supaR) levels were assessed at the 0, third, and sixth months.Results: Ten of fifteen subjects enrolled in this study got better within 3–6 months with a trend of decreasing suPAR level and proteinuria, as well as stable blood pressure and serum creatinine and ureum level. During treatment, no side effects of the subjects were found with the Tac level maintain safely.Conclusion: Tac is an effective and safe agent in treating SRNS, especially for those do not respond well to an alkylating agent.

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