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International Journal of Integrated Health Sciences
ISSN : 23021381     EISSN : 23384506     DOI : 10.15850/ijihs
Core Subject : Health,
International Journal of Integrated Health Sciences (IJIHS) is a peer-review journal which publishes original articles, medical research, clinical research and case report. This journal is supported by Faculty of Medicine Universitas Padjadjaran and was launched on September 22nd 2012 and firstly published on July 2013. The first and second publications in 2013 and 2014 were published annually. In 2015 IJIHS published twice in a year, March and September.
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Articles 199 Documents
Knowledge on and Compliance with Standard Precautions among Medical Students in Jharkhand, India: A Cross-Sectional Study Jawanpuria, Ankita; Dash, Chinmaya
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3711

Abstract

Objective: To assess the knowledge, attitude, and compliance with standard precautions among medical students in a tertiary care hospital in Jharkhand, India.Methods: A total of 280 medical students, including phase I and phase II MBBS students, participated in the study. Phase I comprised an introduction to standard precautions in four-hour classes while the Phase II comprised of 8 hours of theory and three skill assessments on standard precautions according to the CBME curriculum and pandemic module. A structured validated questionnaire was used to collect data on the student's knowledge, attitude, and practice related to standard precautions. The questionnaire included items assessing various aspects of standard precautions, and scoring criteria were used to evaluate student performance. The overall level of knowledge, attitude, and practice was classified as poor (<50% score), moderate (50–79% score), and good (≥80% score).Results: Among the phase I students, 32.8% got a good score. In contrast, in the phase II, 56.6% demonstrated good performance in adhering to standard precautions. The median total score was 68 (interquartile range 62-71) of 85, indicating a satisfactory level of understanding and compliance with standard precautions. However, areas such as needing to remove PPE before leaving the patient's environment and not recapping needles showed rooms for improvement.Conclusion: Students showed good knowledge and compliance with standard precautions. Phase II students demonstrated a better understanding of standard precautions compared to their phase I counterparts. This highlights the positive impact of practical hands-on training as particularly emphasized in the phase II curriculum.
Role of Ultrasound Imaging in Children with Dengue Fever: A Retrospective Study Sean Martin, Juliet Anitha; Annadurai, Karthikeyan
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.4100

Abstract

Objective: To study ultrasound findings of children with dengue and analyze the possible correlation between ultrasound findings  and severity of dengue in children.Methods: This retrospective study, which was conducted over one year, analyzed 50 pediatric dengue patients. Ultrasound findings such as gallbladder wall edema, pleural effusion and ascites were assessed. Cases were categorized into dengue without warning signs, dengue with warning signs, and severe dengue according to the World Health Organization's classification of dengue. Correlation between ultrasound abnormalities,  severity of dengue, and  thrombocytopenia were analyses. A p-value of less than 0.05 was taken as statistically significant.Results: Of 50 pediatric patients diagnosed with dengue participated in this study, 72% were boys, and 28% were girls with a male-to-female ratio of 1:0.38. Fever was the most frequent symptom (100%), followed by nausea/vomiting (84%) and body ache/myalgia (78%). Ultrasound findings revealed that gallbladder wall edema (48%), pleural effusion (44%), and ascites (50%) were significantly associated with severe dengue and dengue with warning signs (p<0.001). Thrombocytopenia was documented in 58% of cases and correlated significantly with ultrasound abnormalities such as gallbladder wall edema, ascites, and pleural effusion (p=0.0017).Conclusion: Ultrasound findings, such as gallbladder wall edema, pleural effusion and ascites, are significantly associated with severe dengue and dengue with warning signs. These features aid in early identification of high-risk patients.
Factors affecting Umbilical Cord Vitamin D Concentration and Its Association with Maternal Vitamin D Level Aggarwal, Aditya; Modi, Amit Kumar; Singh, K. Rimi; Jha, Avinash Kumar
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3963

Abstract

Objective: To analyze factors affecting maternal and umbilical cord levels of vitamin D and to understand the correlation between maternal and umbilical cord vitamin D levels.Methods: This was a cross-sectional study conducted at the department of pediatrics of Dr. D. Y. Patil Medical College and Research Centre, Pune, India. Maternal and umbilical cord vitamin D levels were examined in 300 pairs of mother and child over a period of two years. Informed consent was obtained from all participants. The vitamin D level was measured using chemiluminescent immunoassay and classified as either deficient, insufficient or adequate depending on specific cut-offs. Correlations between maternal and neonatal vitamin D levels and demographic factors like religion, socioeconomic status, and sun exposure were also exlored. Statistical tests were performed using the SPSS 21.0 software, with p<0.05 deemed P-valueas significant.Results: There was significantly high prevalence of vitamin D deficiency in neonates, (78.67%). Key factors influencing maternal vitamin D levels were religion (p=0.027), maternal education (p=0.003), gravida status (p=0.035), and sunlight exposure, with sunlight exposure showing a very strong correlation to the deficiency (p<0.001). Moreover, maternal serum calcium levels significantly affected vitamin D status (p<0.001). A significant association was observed between maternal and cord blood vitamin D levels, with the maternal vitamin D level strongly predicted vitamin D status in neonates (p<0.001).Conclusion: The umbilical cord vitamin D level strongly correlates with the maternal vitamin D level, which is  significantly affected by maternal education, residence, pregnancy status, gestational age, and sun exposure.
Nutrition Education Effect in Increasing Knowledge and Ability to Interpret Nutrition Facts in Adolescents Meylinda, Jovita Octa; Arinda, Ditia Fitri; Yuliana, Indah; Sari, Desri Maulina
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3564

Abstract

Objective: To evaluate the effectiveness of nutrition education on the understanding and proficiency in interpreting nutrition labels among adolescents aged 16-18 years..Methods: This quantitative study adopted quasi-experimental and control group designs with a pre-test and post-test approach. The sample size included 60 participants, divided into 2 equal groups, receiving education through lecture method and leaflets, respectively. The intertervention was conducted one day in group 1 and group 2, respectively. Sample selection was conducted using a simple random sampling method. Data were collected through a knowledge questionnaire and details on reading ability were obtained using an interpreting ability checklist through pre-tests and post-tests conducted at the same day. The retrieved data were analyzed using the Wilcoxon Signed Rank Test and the Mann-Whitney U Test (α=0.05).Results: Nutrition education is shown to enhance the understanding (p-value=0,026) and proficiency of students in interpreting nutrition facts (p-value=0,064).Conclusion: Nutrition education had a positive impact on the understanding and skill of adolescents in reading nutrition facts. Thus, developing educational materials that can be readily applied in daily life will help consumers in making more nutritionally informed choices when selecting packaged foods.
Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study Goyal, Lalit; Gupta, Saloni; Nagar, Sachin; Bhargava, Vinay
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3988

Abstract

Objective: To assess feasibility, safety, and efficacy of segmental spinal anesthesia with isobaric levobupivacaine in patients undergoing various abdominal and lower limb surgeries. Methods: This was a prospective cohort study conducted at the Department of Anesthesiology and Critical Care of Kota Heart Institute and group of hospitals in India. The study involved  100 patients undergoing various abdominal and lower limb surgeries under segmental spinal anesthesia (SSA). Isobaric levobupivacaine 0.5% with fentanyl 20-25 μg or dexmedetomidine 5-10 as adjuvant or  hypobaric levobupivacaine 0.167%  was injected in intervertebral space depending on the surgery. Hemodynamic parameters, postoperative pain level, and adverse effects were analyzed with a p-value less than 0.05 was considered statistically significant.Results: An overall male predominance was observed with a 1:0.515 male-to-female ratio. The most affected age group was 41-50 years (37%), with a mean age of 44.51 ± 11.72 years. ASA classification indicated 34% of patients in ASA I, 40% in ASA II, 24% ASA III and 2% in ASA IV . The primary surgery was laparoscopic cholecystectomy (26%) in normal risk group and orthopedic in high-risk group(20%). Postoperative pain assessment showed mean VAS scores ranging from 1.92 to 3.42 at different time intervals. Common adverse effects were hemodynamic instability (13%), shoulder tip pain (33%), PONV (3%), headache (6%), pruritis (2%) and urinary retention (1%). The hemodynamic instability showed less incidence in ASA III/IV category.Conclusion: Segmental spinal anesthesia can be used successfully for abdominal and lower limb orthopedic surgeries in patients of ASA I to ASA IV.
Tacrolimus Therapy Among Steroid-Resistant Nephrotic Syndrome Children: A Preliminary Study in West Java, Indonesia Widiasta, Ahmedz; Wahyudi, Kurnia; Rachmadi, Dedi
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3663

Abstract

Objective: To explore the outcomes of Tac therapy for Steroid-Resistant Nephrotic Syndrome (SRNS) and its implication in reducing the number of CKD events.Methods: An open, prospective, cohort study was conducted at a tertiary hospital in Bandung, West Java, Indonesia. Children (age 1–18 years old) with steroid and cyclophosphamide resistant nephrotic syndrome were enrolled in this study. Blood pressure, urinary protein, serum ureum, and creatinine levels were measured every month, Tac and soluble urokinase plasminogen activator receptor (supaR) levels were assessed at the 0, third, and sixth months.Results: Ten of fifteen subjects enrolled in this study got better within 3–6 months with a trend of decreasing suPAR level and proteinuria, as well as stable blood pressure and serum creatinine and ureum level. During treatment, no side effects of the subjects were found with the Tac level maintain safely.Conclusion: Tac is an effective and safe agent in treating SRNS, especially for those do not respond well to an alkylating agent.
Role Of High-Resolution CT Thorax in Interstitial Lung Disease Evaluation Singh, Surinder; Jain, Tripti; Kaur, Amarjit; Chhabra, Harinder Singh
International Journal of Integrated Health Sciences Vol 13, No 1 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n1.4326

Abstract

Background: High-Resolution Computed Tomography (HRCT) plays a crucial role in the evaluation of interstitial lung diseases, offering detailed imaging for accurate diagnosis.Objective: To evaluate diagnostic precision and clinical relevance of High-Resolution Computed Tomography (HRCT) in evaluating Interstitial Lung Diseases (ILDs).Methods: This observational study analyzed HRCT images from 30 patients using a multi-detector CT scanner. The study was conducted at the Department of Radiodiagnosis of Gian Sagar Medical College and Hospital, India, in a period of one year (January 2024 to December 2024). Images were reviewed by two radiologists for various features, including ground-glass opacities, reticulations, honeycombing, and traction bronchiectasis. The patterns were classified as definite UIP, probable UIP, or suggestive of chronic HP or NSIP.Results: Eighteen patients (60%) showed basal-predominant honeycombing, reticulations, and traction bronchiectasis consistent with definite UIP. Six of these also exhibited upper lobar emphysema, categorized as Combined Pulmonary Emphysema and Fibrosis (CPFE). Another six patients with NSIP displayed subpleural curvilinear opacities, fine reticulations, and ground-glass abnormalities. Six (20%) patients with chronic HP showed diffuse ground-glass opacities and traction bronchiectasis, primarily in the upper lobes with air trapping on expiratory scans.Conclusion: This case series demonstrates the diverse HRCT findings in ILD, underscoring the importance of HRCT in diagnosis and prognosis. Larger studies with histopathological confirmations are needed to refine these diagnostic insights.
General Anesthesia Management of Super Refractory Status Epilepticus in Anti-N-Methyl-D-Aspartate-Receptor (NMDAR) Meningitis Amalia, Putri Shabrina; Setiawan, Irvan; Melati, Annemarie Chrysantia
International Journal of Integrated Health Sciences Vol 13, No 1 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n1.3881

Abstract

Background: Super Refractory Status Epilepticus poses significant management challenges, requiring intensive therapeutic approaches including general anesthesia.Objective: To discuss the management of Super Refractory Status Epilepticus (SRSE) with general anesthesia to control seizures.Case Illustration: A 17-year-old female with tonic-clonic seizures, headache, unclear speech, and a change in behavior, who also appeared to be restless, was presented. She was admitted to the intensive care unit and administered anticonvulsant medication. A brain MRI with contrast showed the impression of meningitis, and cerebrospinal fluid examination showed a positive anti-NMDAR result. First-line therapy involved high-dose steroids and intravenous immunoglobulin for 5 days, followed by second-line therapy with rituximab. Patient received general anesthesia using sevoflurane volatile, dexmedetomidine, continuous rocuronium, propofol, ketamine, and fentanyl due to persistent seizures despite receiving anticonvulsant therapy. Monitoring was conducted for vital signs, seizure activity, and depth of anesthesia using the bispectral index (BIS). Tonic-clonic seizures in patients were successfully managed with general anesthesia. However, facial dyskinesia was still present despite the administration of general anesthesia. Facial dyskinesia worsened upon discontinuation of continuous rocuronium.Conclusion: General anesthesia could be used in the management of SRSE with the aim of controlling seizures and preventing complications arising from continuous seizures.
HER2 Reactivity Pattern and Association with Various Tumor Factors in Breast Cancer Patients George, Greeshma Ann; Antony, Philips
International Journal of Integrated Health Sciences Vol 13, No 1 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n1.4017

Abstract

Background: Breast cancer prognosis and therapeutic strategies are strongly influenced by biomarker profiles, particularly HER2 reactivity, which impacts treatment selection and disease progression.Objective: To study the HER2 reactivity pattern and identify the association of HER2 pattern with various tumor factors in patients with breast cancer.Methods: This prospective study comprised of 150 surgically operated female cases of breast cancer admitted to the Department of Pathology for ER, PR, and HER2 testing between December 2015 and October 2017.Results: Of 150 cases, the mean age was 52 years (IQR, 41-63 years). This study showed that majority of tumors were IDC-NOS, grade 2, tumor size T2, and had negative lymph node status. HER2 negative cases were in the majority, as well as the ER/PR+ cases. Triple-negative cases were slightly higher (49 cases). When HER2 was correlated with tumor characteristics, younger patients with HER2-positive were in the majority, with the higher the tumor size is, the greater the chance for HER2 negativity. The majority of IDC cases and all ILC cases showed HER2 negativity. Both medullary cases showed HER2 positive, and one case of mucinous showed HER2 negativity with ER/PR positivity. Irrespective of ER/PR status, the majority of tumors had HER2 negativity.Conclusion: HER2/neu positively correlates with increasing age, menstrual status, tumor size, and tumor grade. No association is found between histological type, lymph node status, and ER/PR. This study also reveals that patient with higher levels of HER2/NEU-overexpression had statistically significant lower levels of ER/PR-positive tumors. In addition, when Her2 neu is positive in tumors, along with ER and PR, it is mostly high-grade.
Assessment of Disease Progression in Idiopathic and Collagen Vascular ILDs Using Spirometry, DLCO, and 6 Minute-Walk-Test Rawul, Sindhoora; Kumar, R. Vijai; Rawul, Apoorva; Chelluri, Srinivasa I.; Singaraju, Saikrishna
International Journal of Integrated Health Sciences Vol 13, No 1 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n1.4327

Abstract

Background: Monitoring progression in interstitial lung diseases is essential for timely intervention, with spirometry, DLCO, and 6MWT serving as key functional tests.Objectives: To evaluate disease progression in idiopathic and collagen vascular interstitial lung diseases (ILD) using pulmonary function parameters, including spirometry, DCLO (Diffusing Capacity of the Lungs for Carbon Monoxide), and the six-minute walk test.Methods: This prospective observational study was performed from January  2023 to December 2024 at Shadan Institute of Medical Sciences , Hyderabad, India. In this study, the pulmonary function in 51 ILD patients were assessed using spirometry, DLCO, and the six-minute walk test. Patients underwent detailed clinical evaluation, routine investigations, chest X-ray, ABG analysis, and HRCT to confirm ILD. Those suspected of CTD-ILD had RF and ANA testing, with a complete ANA profile if positive. Subjects were categorized into IPF and CTD-ILD groups. Pulmonary parameters were compared, and standard treatments were administered. Six deaths occurred during follow up period.  For statistical purposes p value less than 0.05 was taken as statistically significant.Results: Fifty-one patients with diffuse parenchymal lung disease were included, with idiopathic pulmonary fibrosis (IPF) (46.4%) and connective tissue disease-associated ILD (CTD-ILD) (44.6%) as the main types. The CTD-ILD patients were younger (mean age 48.64 vs. 61.80 years, p=0.0006) and predominantly female. IPF patients had lower six-minute walk distance (239.73 vs. 312.60 meters, p=0.0066) and SpO2. Strong correlations were observed between lung function parameters in both groups. However, 6MWT showed no correlation in CTD-ILD.Conclusion: In ILD patients, FVC and DLCO were found to be reliable for disease monitoring, while simpler tests like 6MWT and FVC proved to be useful in resource-limited settings. Further research is needed to confirm their role in tracking IPF progression and treatment response.