Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles
2,170 Documents
Cost effectiveness of cotrimoxazole and ampicillin on urinary tract infection in children on direct medical aspect
Dyah Harini, Dyah Harini
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 4 (2004)
Publisher : Universitas Gadjah Mada
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Background: Urinary tract infection (UTI) is one of the important diseases causing significant morbidity in infants and children. The true incidence of UTI in children is difficult to estimate because infection in infants and children can be asymptomatic. Delay in the treatment of UTI can lead to recurrent infection resulting in renal scarring or complication with urosepsis. Physicians use a large number of different antimicrobials and give them for widely varying durations to children and infants with suspected UTI. More standardized use of the most effective, best tolerated and least costly treatment regimens would have considerable benefit both in reducing morbidity and health care costs.Objective: The aim of this study is to compare of ampicillin compared to cotrimoxazole oral treatment in UTI childrens.Methods: This study was used clinical trial design. A total of 1-10 child patients in Dr. Sardjito Hospitalwith urinary tract infection older than 2 months age who enaolled in this study were randomly assigned to receive either ampicillin (57 children) or cotrimoxazole (53 children). Diagnosis was based on clinical and laboratory criteria. Laboratory diagnosis was established based on bacterial count and urine culture tests. The cure rates were assessed after seven day treatment based on clinical and laboratory evalua- tion. Chi-square test was applied to analyse the difference of clinical outcomes between ampicillin and cotrimoxazole groups. Logistic regression analysis was applied to analyse the relationship of variable that influence the outcomes. Cost analysis accounted by direct cost (medical, length of stay, laboratory cost)between two groupsResult: Mean of the length of stay of cotrimoxazole patient was shorter than ampicillin patients. It was also found that E coli was the most frequent (45.4%) microbes detected in the urine culture. There were no significant differences in the sensitivity of the microbes to both antibiotics. The results indicated that cotrimoxazole showed significant differences in the effectiveness (p<0.05).Conclusion: Cotrimoxazole treatment on UTI is as effective as ampicillin. Cotrimoxazole costs cheaper.Key words:Â ampicillin- cotrimoxazole - cost- urinary tract infection- cure rate- urine culture- bacterialcount
Keracunan Makanan Bakterial dan Botulisme
Ilyas, Ilyas
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 04 (1974)
Publisher : Universitas Gadjah Mada
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kata kunci : keracunan makanan
Poland anomaly associated with ocular anomalies
Hartono, Hartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 01 (1992)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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A 6-year old boy suffering from Poland anomaly has been reported. The patient showed a complete picture of this malformation which consisted of aplastic greater pectoral muscle and breast on the left side of the chest, as well as oligodactily of the left hand.Other anomalies found were ocular and oral anomalies. The ocular anomalies consisted of hypertelorism, bilateral esotropias due to bilateral abducent palsy, and bilateral optic nerve hypoplasia. Oral anomalies consist of the inability to close the mouth properly and the inability to smile may be due to the defect of oral muscles.Key Words: Poland anomaly - chest anomaly - oligodactily - ocular anomalies - oral anomalies
Ilmu Kedokteran Dasar
Soemiati Ahmad Muhammad, Soemiati Ahmad Muhammad
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 04 (1980)
Publisher : Universitas Gadjah Mada
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Katakunci: ilmu kedokteran dasar
Pendekatan rasional terapi infeksi saluran kemih pada USILA (usia lanjut)
I Gde Raka Widiana, I Gde Raka Widiana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 01 (1996)
Publisher : Universitas Gadjah Mada
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Aging may affect functional and structural changes of the urinary tract which modify the response against infection. Sructural changes in elderly such as prostate hypertrophy, urinary tract stone, the use of catheter, and the presence of cystoceles should be treated properly. Attention should be paid on functional abnormalities in elderly including bladder atonia, neurologic defects, and prolonged bed rest. Inadequate immune response in elderly may also play a role in the changes. Those factors make the treatment of urinary tract infections in elderly have to be carried out more radically.Complicated urinary tract infections, infection in males with prostate hypertrophy, and pyelonephritis need prolonged treatment. Recurrent urinary tract infections in female elderly patients need early prophylactic treatment. Doing a culture of the causative microorganisms and a sensitivity test for the appropriate antibiotics should be taken into consideration in the selection of the antibiotics. Flouroquinolones and cephalosporins seem to be drugs of choice in multiresistant and severe casesKey words: urinary tract infections - elderly - functional changes - structural changes - treatment
Congenital cataract: A case report of two sisters
Hartono, Hartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 04 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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Two sisters suffering from bilateral congenital zonular cataract have been reported-. Their parents and their one and only sister were perfectly normal. The older sister was 2 years old whereas the younger was 8 months when they were first examined and they immediately underwent discission and evacuation. It was likely that the two cases carried autosomal dominant genes for congenital zonular cataract, either non-penetrant genes or a fresh mutation of the germ cell of one of their parents. In the former the recurrence risk was 50%, whereas in the latter such risk was practically zero. Key Words: congenital zonular cataract - autosomal dominance - non-penetrant gene - fresh mutation - recurrence risk
Hyperbilirubinemia in the newborn infants; unbound bilirubin approach
Achmad Surjono, Achmad Surjono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 01 (1995)
Publisher : Universitas Gadjah Mada
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A guideline for management of hyperbilirubinemia in the newborns based solely on total/indirect serum bilirubin levels is considered outmoded. An approach to the identification of newborns at risk of bilirubin toxicity due to the increase of unbound bilirubin is proposed. Unbound bilirubin can easily enter the brain and bind to the nerve cells.A peroxidase oxidation method using unbound bilirubin - analyzer (UB-analyzer) offers a rapid, accurate and reproducible measurement of unbound bilirubin. Phototherapy, either continuous or intermittent can be applied to term and preterm infants on the monitoring of unbound bilirubin levels.Temporary cessation of breast-feeding is not advised in healthy term newborns with hyperbilirubinemia. On the contrary, more frequent feeding is advocated. Caution and substitution should be taken in giving any drugs having a potent displacer on bilirubin-albumin binding, especially In premature infants.Key words : newborn infants --hyperbilirubinemia -- unbound bilirubin -- phototherapy -- displacing drugs
Influence of catheterization on the prostate specific antigen level in patient suffering from prostate disorder
Osman Sianipar, Osman Sianipar
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 03 (2005)
Publisher : Universitas Gadjah Mada
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Background: The increase of life expectancy may increase the number of patients suffered from prostate disorder. In Indonesia prostate cancer is in the top ten malignancies in men and is the second most frequent malignancies in urology clinics. Early detection may decreasies its fatality rate and increase the quality of life. Prostate specific antigen (PSA) is clinically the most useful tumor marker; its serum level has positive correlation with the prostate cancer. Serum PSA level will also increase in inflammation, benign prostate hyperplasia (BPH) and interventions like catheterization, digital rectal examination and biopsy.Objective: The objective of this study is to examine the catheterization effect for the result of PSA test in patients with prostate disorder.Methods: Subjects of study are all of patients who present symptoms related prostate. Venous blood samples are taken using aseptic technique then processed further to collect serum. Level of PSA is determined by ELISA technique from the serum. Study population is grouped according to result of histopathologist examination namely benign prostate hypertrophy, benign prostate hypertrophy with prostatitis, benign prostate hypertrophy with prostate intraepithelial neoplasm and prostate cancer. In addition, patients are also grouped into group that already catheterized and those who have not been catheterized before blood sample was taken. One-way ANOVA and Pearson correlation were used to analyse the effects.Result: Mean of PSA level in patients sufferring from benign prostate hypertrophy, benign prostate hypertrophy with prostatitis, benign prostate hypertrophy with prostate intraepithelial neoplasm respectively were 17.61 ng/mL, 17.33 ng/mL and 19.77 ng/mL. This was significantly different compared to those in the same group but without catheterization before blood collection. Mean of PSA level in prostate cancer patient was 38.3 ng/mL. It was not significantly different to those in prostate cancer patient but without catheterization before blood collection.Conclusion: Urine catheterization prior to determination of PSA level showed an effect to increase PSA level in the group of patients presenting complain of related prostate but it is not found in protate cancer patient.Key words: PSA - prostate disorder - prostate cancer - catheterizationÂ