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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 57   58   59   60   61 
Hasil Pengamatan Diagnosa Klinik Terhadap Diagnosa Patologi pada Penderita Radang Usus Buntu Prawito, Prawito
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 02 (1980)
Publisher : Universitas Gadjah Mada

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Abstract

The purpose of this paper is to review 309 patients of appendicitis operated in the Department of Surgery, Gadjah Mada University Hospital, Yogyakarta, between 1972 - 1976. Among the pa. tients 81 are males and 228 are females. The peak incidence of appendicitis is between 15 - 20 years of age. Results of the clinical diagnosis compared with the pathological diagnosis are as follows;81,8% is chronic appendicitis; 44,4% is acute appendicitis; 64,4% is chronic appendicitis with acute exacerbation; 60% is periappendicular infiltrate and 1,9% is normal appendix.Fecaliths within the lumen-of the appendix are found in 136 patients (44%); eggs of elscaris in 8 patiens (2,6%).Key Words: appendicitis - periappendicular infiltrate - Ascaris - normal appendix - fccaliih
Interactions of the immunocompetent cells in bronchial asthma Marsetyawan HNE Soesatyo, Marsetyawan HNE Soesatyo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 04 (1995)
Publisher : Universitas Gadjah Mada

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Abstract

The presence of immunocompetent cells in the respiratory tract and their cellular interactions are undoubtedly crucial, leading to the development of bronchial asthma in hypersensitive individuals. The cells comprise various populations, such as mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells and lymphocytes, in which the T-cells are believed to play a central role. It has been demonstrated that CD4+ T-cells consist of CD45RO reactive population and CD45RA, each secreting different cytokines. In terms of cytokine pattern production, these T-cell subpopulations are similar, to those found in the murine system, i.e. TH1 and TH2 cells. The CD45RO+ IL-4 and IL-2 cells produce directly or indirectly that govern the proliferation and differentiation of B-cells to IgE-secreting plasma cells, by which IgE antibodies are responsible for the development of allergic type I reaction. In addition, the number of T-cells expressing activation markers, like IL-2R, VLA-1 and HLA-DR increases in the serum of asthmatic patients, as well as in their bronchoalveolar lavage and bronchial biopsies. Moreover, the CD4+ T-cells produce IL-3, GM-CSF, IL-4, IL-5, IL-6 and IL-10 that induce mast cell differentiation and activation and recruitment of eosinophils. The function of dendritic cells and macrophages in antigen presentation to either naive or activated T-cells should be noted. Finally, immunologic-based therapy for the airways hyperreactivity may be proposed. This concept includes the regulation of certain cytokine production governing TH1 subpopulations, and by eliciting an optimal mucosal IgA response to down-regulate the production of IgE antibodies.Key Words: bronchial asthma - immunocompetent cell interactions - T-cell subpopulations - T-cell cytokines -                 mucosal IgA response
Karsinoma Payudara pada Laki-Laki Laporan Kasus dan Tinjauan Pustaka Endang Soetristi, Endang Soetristi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 01 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Carcinoma of the male breast occurs so infrequently. Several articles reported that the relative frequency ranges between 0.46% —2% of all breast carcinoma. The histologic types of the male breast carcinoma were relatively the same as in the female, but in the male, lobular carcinoma and carcinoma with metaplasia were never found. The disease commonly occurs in elderly men, from the late fifth through the seventh decade, and in women it usually occurs before menopause. This situation suggests that estrogen has an important role in the pathogenesis of breast carcinoma. Two cases of male breast carcinoma were reported. One occurred in a man aged 28 years. The histologic type was papillary carcinoma with mucoid degeneration. The other occurred in an older man aged 70 years with infiltrating duct carcinoma. The latter case could support the important role of estrogen in causing carcinoma. But the other one, cannot support this. It must be thought that there are other factors, such as in genetic syndromes. Key Words: male breast carcinoma — estrogen — oncology — genetic syndromes — neoplasm
Kasus penderita sakit mata di Klinik Mata Dili
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 9, No 04 (1977)
Publisher : Universitas Gadjah Mada

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Abstract

Keywords: penderita sakit mata-kasus
Epidemiologi Pemakaian Obat Peranannya Want Peningkatan Kualitas Pelayanan Kesehatan Budiono Santoso, Budiono Santoso
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 20, No 03 (1988)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Drug utilization has been defined as "the marketing, distribution, prescription and use of drugs in a society, with special emphasis on the resulting medical, social and economic consequences". The aim of drug utilization study is to achieve optimal use of drugs in a society, i. e. safe, efficacious, rational and cost-effective. Various benefits can be obtained from drug utilization study which by all means may increase the quality of patient care.Drug utilization study may be classified into two types based on its specific aim. First routine monitoring of drug use in a society which is aimed at examining the general pattern of drug use and predicting the forthcoming trends, and second special drug utilization study which is aimed at investigating specific study questions and hypothesis.Review of the pattern of drug utilization is likely becoming and effective feedback to the prescribers and drug policy makers towards more rational use of drugs.Key Words: drug utilization - patient care - drug policy - pharmacoepidemiology - drug abuse
Correlation between immediated pigmentation with oxydative DNA repair. A study among elementary school children under sun exposured sport activity Retno Mustikaningsih, Retno Mustikaningsih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 02 (2005)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Oxydative DNA damage, namely 8-OHdG, may occurred due to DNA oxydation by reactive oxygen species (ROS). Unrepaired 8-OHdG may initiate a carsinogenesis due to G to T transversion of gene point mutations. The 8-OHdG repair can be measured by determination of urinary 8-OHdG level. It is well known that ROS reaction with preexisting melanin may perform an immediate pigmentation darken-ing (IPD) and it can be measured by mexameter. The correlation between IPD and 8-OHdG repair capacity is still not known.Aim of Study: To know the correlation between IPD and 8-OHdG repair ability in order to predict the oxydative DNA repair capacity.Methods: Using of a quasi experimental design, 8-OHdG urine level alteration correlated with skin color alteration after oxydative stress among 30 healthy elementary-school children during sport activity pro-gram under sun exposure. 24 hours of skin color alterations as a IPD were measured by mexameter, and urinary-8- HdG- level were measured based on ELISA with 8-OHdG-Kit antibody. The correlation be-tween IPD and     8-OHdG urine level alteration was analyzed with Spearman test.Results: There was a very significant correlation between immediate pigmented darkening and urinary                      8- OHdG level alteration (r=0.8562; p<0.01).Conclusion: IPD represents 8-OHdG repair capacity after oxydative stressed under sun exposure Keyword: immediate pigmention darkening -  8-OHdG -mexameter - sun exposure 
PENGANUGERAHAN DERAJAT DOCTOR HONORIS CAUSA Sukadji Ranuwihardjo, Sukadji Ranuwihardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 8, No 03 (1976)
Publisher : Universitas Gadjah Mada

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Abstract

kata kunci : anugerah Doktor Honoris Causa
Trauma di bagian mata fakultas kedokteran Universitas Gadjah Mada Gunawan, Gunawan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 03 (1973)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keywords: tunanetra, trauma mata, galucoma, infeksi gonococcus
Hepatitis-C virus (HCV) Suwarso, Suwarso
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

A new problem on hepatitis for Indonesian is hepatitis-C virus (HCV). This infection is endemic, majority sub-clinic and progressive in chronic. Viral transmission is primarily via a parenteral route, while other routes are still in debate.Diagnostic approach should be focused on how this virus developed.KeyWords: hepatitis-C virus molecular biology Westem-blot-HCV blood transfusion epidemiology
Cerebrotendinous xanthomatosis Soedarmadji, Soedarmadji
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 03 (1983)
Publisher : Universitas Gadjah Mada

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Abstract

A case of cerebrotendinous xanthomatosis in an Indonesian male, 25 years of age, is reported. The diagnosis was based on clinical features, laboratory and histopathologic examinations, without measurement of cholestanal concentration either in the plasma or in the xanthoma.Key Words: xanthoma - normolipidemia lipoidosis - cataracta juvenilis - neurologic disturb 

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