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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 60   61   62   63   64 
Medical Biotechnology : Its Impact on Societys Teuku Jacob, Teuku Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 04 (1990)
Publisher : Universitas Gadjah Mada

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Abstract

Karangan ini memberi pandangan bioanthropologis tentang dampak sosial bioteknologi medis. Dimulai dengan definisi bioteknologi dalam arti luas dan sempit, lalu diteruskan dengan tinjauan tentangcara, balk yang modern maupun yang tradisional, kemudian diakhiri dengan uraian tentang dampak biososial, ekologis, evolusioner, demografis, ekonornis, politis, militer, hukum, sosiokultural dan agama, yangdapat men imbulkan perubahan-perubahan mendasar4alam masyarakat dunia.Di antara cara-cara bioteknologi yang disinggung adalah eufenetika, eugenetika, transplantasi dan substitusi organ, genoteknologi dan teknologi reproduksi. Ke dalam yang terakhir termasuk peijodohan terpimpin, pengendalian pembuahan, pembuahan anumerta, dan in vitro, fusi embryo dan pencangkokan nukleus, hybridisasi sel dan klonasi. Di antara cara-cara tradisional dikemukakan system Itasca, pengebirian, pengguguran, infantisida, perjodohan terpimpin dan manipulasi lingkungan.Diingatkan tentang dampak negatif yang merugikan manusia dan ekos-ystemnya, karena alchimya aspekteknologis kehidupan tidal( dapat di pisah kan dari aspek-aspek politis,sosial dan ethis.Key Words: biotechnology - euphenics - eugenics - reproductive technology -- guided mating
Risk factors of neonatal asphyxia on storm baby Novita Dewi, Novita Dewi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 03 (2005)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Neonatal asphyxia remains the main cause of neonatal mortality as well as permanent neurological abnormality. With informed consideration about risk factors, more than half fetuses who need resuscitation could be identified prior to birth.Objectives: The study was aimed to identify antepartum and intrapartum risk factors in neonatal asphyxia of full term babies.Study Design: Case control.Material and Method: Data were collected from medical record of babies hospitalized in Subdivision of Perinatology, Department of Child Health in Dr. Sardjito Hospital in January to December 2004. The risk factors of neonatal asphyxia were identified before and during delivery. Data were analized using chi square, bivariate and multivariate analysis.Results: In multivariate analysis, antepartum factor which increases the risk of neonatal asphyxia was small for gestational of age (SGA) baby (OR: 3,43; CI 95%: 1,81-6,53). Intrapartum factors that increased the risk of neonatal asphyxia were meconium stained of amnion fluid (OR:  49,02; CI 95%: 12,34- 143,67), prolonged second stage of delivery (OR: 9,73; Cl 95%: 3,99-23,99) and Caesarean section delivery with general anesthesia (OR:  8,62; CI    95%: 2,16-34,44).Conclusion: SGA baby, meconium stained of the amniotic fluid, prolonged second stage of delivery and Caesarean section delivery with general anesthesia increased the risk of neonatal asphyxia in full term baby.Key words: risk factors - neonatal asphyxia - aterm babies
Ilmu kedokteran dan media massa T. Jacob, T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 04 (1978)
Publisher : Universitas Gadjah Mada

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Abstract

Keyword: Ilmu kedokteran, media massa
Trait genetik biokimia yang berkaitan dengan malaria pada penduduk P. Alor. keuntungan lain terhadap virus hepatitis-B? Abdul Salam M. Sofro, Abdul Salam M. Sofro
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 02 (1995)
Publisher : Universitas Gadjah Mada

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Abstract

Meskipun secara geografis, budaya dan antropologi ragawi orang Alor berhubungan erat dengan penduduk Nusa Tenggara Timur lainnya yang berada dalam Master Indonesia timur, tetapi dengan analisis jarak genetik mereka berada sedikit di luar. Namun demikian secara umum populasi Indonesia khususnya populasi di Nusa Tenggara telah lama terpapar.faktor seleksi alam yang kurang lebih sama yaitu malaria. Di samping itu, kawasan ini dikenal memiliki prevalensi infeksi virus hepatitis B (HBV) cukup tinggi.Penelitian ini dimaksudkan untuk melihat trait genetika biokimia yang mencirikan pola klinal populasi di Indonesia Berta yang barangkali menawarkan keunggulan selektif terhadap malaria yang merupakan salah satu faktor seleksi alam utama di daerah Alor. Di samping itu juga akan dipelajari kemungkinan antaraksi trait genetik tersebut dengan hepatitis.Hasil pemeriksaan sistem golongan darah ABO menunjukkan tingginya frekuensi golongan darah 0 (49,18%), sedangkan A dan B masing-masing 24,59°.6 dan 23,77%. Hasil ini agak berbeda dengan distribusi di Yogyakarta dengan populasi yang lebih Mongolid dengan frekuensi golongan darah B agak tinggi (29,23%) sebagaimana kebanyakan populasi Asia Tenggara. Dari tiga trait yang terkail dengan malaria, lidak satupun HbE atau pengemban thalassemia-fi ditemukan dari 122 subjek yang diperiksa. Namun demikian, kekurangan glucose-6-phosphate dehydrogenase (G6PD) ditemukan pada 8 subjek (6,6%) dan ovalositosis pada 15 subjek (12.3%). Dari pemeriksaan HBsAg yang dapat dilakukan pada 109 subjek, didapatkan 13 subjek dengan HBsAg positif. Yang menarik,.dari 7 subjek dengan kekurangan G6PD hanya satu subjek menunjukkan HBsAg positif, sementara tidak satupun dari 8 subjek ovalositosis menunjukkan HbsAg positif. Meskipun secara statistik tidak bermakna, kemungkinan bahwa gena mutan khususnya untuk ovalositosis memiliki keunggulan selektif terhadap infeksi hepatitis perlu dipikirkan. Mungkin saja bahwa gena mutan diekspresikan di sel hati yang menyebabkan gangguan adsorbsi dan penetrasi virus ke dalam sel hati. Diperlukan penelitian lebih lanjut untuk dapat menjelaskan fenomena yang menarik ini.Key words : biochemical genetic trait - glucose-6-phosphatedehydrogenase deficiency - ovalositosis--p. thalassemia
Kebutaan Akibat Kelainan di Fundus A. Soemarsono, A. Soemarsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 17, No 01 (1985)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The mechanism of blindness by fundus anomalia was presented. The criteria of blindness were determined by visual acuity 3/60 or less. During a one-year period from januafy to December 1983 there were found 71 cases of blindness of both eyes and-78 cases of blindness of one eye. The kinds of blindness found at Dr. Sardjito Hospital were retinitis/choziorecinitis 27 patients, retinopathy 17 patients, glaucoma 69 patients, N 11 atrophy 16 patients, macula degeneration 2 patients, and retinal bleeding 2 patients, All the blindness were irreversible. Key Words: blindness - fundus anomalia - chorioretinitis retinopathy glaucoma
Iklan Obat Anonim, Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 02 (1994)
Publisher : Universitas Gadjah Mada

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Abstract

Kata Kunci: Promosi - Obat
Tegralogy of Fallot: Pro-and post-surgical case study A. Samik Wahab, A. Samik Wahab
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 04 (1989)
Publisher : Universitas Gadjah Mada

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Abstract

Defects in the ventricular septum with obstruction to right ventricular outflow encompass a wide anatomic, physiologic and clinical spectrum. Large ventricular septal defects occur with pulmonic stenosis that varies from mild to severe to complete (pulmonary atresia). Small ventricular septal defects occur with mild to severe pulmonic stenosis. The most familiar and prevalent combination is tetralogy of Fallot with the incidence of approximately 0.4 to 0.6 per 1000 live births.The following illustrates four cases of Fallots tetralogy with a wide anatomic, physiologic and clinical variations. The first case is a small ventricular septa defect along with severe pulmonic stenosis, the fourth case, however, comprises a large VSD and pulmonary atresia, while in the others the anatomic variations are in between.Hypoxic spells are important aspects of the history in Fallots tetralogy. Spells are an alarming episode that should be treated as an emergency. Knee-chest position, squatting or sitting with legs drawn underneath can afford to relief dyspnea.The best treatment, however, is surgical treatment, indicated in all patients with Fallots tetralogy. The result of this surgical treatment up to now is very satisfactory.Key Wards: tetralogy of Fallot - pulmonic stenosis - ventricular septal defect - pulmonary atresia - bicuspid a pulmonalis
The effect of the administration of vitamin K2 to the pregnant women on the activities of prothrombin group in cord blood. Rahajuningsih D. Setiabudy, Rahajuningsih D. Setiabudy
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 1 (2004)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Hemorrhagic disease of the newborn (HDN) is a hemorrhage at the neonatal period. The most dangerous form of HDN is intracranial bleeding which may be fatal. The most frequent cause of HDN is deficiency of vitamin K dependent factors or prothrombin group.Objective: The aim of the study is to know the effect of the administration of vitamin K2 to the pregnant women on the activities of prothrombin gourp in cord blood.Methods: This was experimental design. Forty pregnant women were enrolled in this study. Vitamin K2 was given orally at the dosage of 10 mg twice daily. At delivery the cord blood was collected for the measurement of prothrombin group activities.Results: In the treatment group the median activities of prothrombin were 37.3%, F VII were 62.4%, F IX were 29.5%, and F X were 34.9%, while in the control group the median activities of prothrombin were 33.5%, F VII were 47.3%, F IX were 23.7%, and F X were 29.0%. The difference of the activities of vitamin K dependent factors between treatment group and control group was statistically significant. Conclusion: The administration of vitamin K2 to the pregnant women increases the activities of vitamin K dependent factors in the cord blood.Key words: hemorrhagic disease of the newborn - oral vitamin K2 - cord blood - vitamin K dependent factor activity
Perobahan-Perobahan Neuroendokrinal dan Psikis Pada Masa Senium Radiopoetro, Radiopoetro
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 7, No 04 (1975)
Publisher : Universitas Gadjah Mada

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Abstract

key words: perubahan psikis pada usia lanjut
Characterization of antigens of hookworm larvae (Ancylostoma spp.) Sri Sumarni, Sri Sumarni
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 04 (1992)
Publisher : Universitas Gadjah Mada

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Abstract

Cutaneous larva migrans (CLM) is caused by animal hookworm larvae in man. The conventional diagnosis and treatment of CLM will injure the skin of the patients, and the results are not satisfying. Therefore it should be necessary to do the serological test to diagnose CLM.The antigens were prepared by extracting the hookworm larvae in CTAB detergent, and injected into Balb/C mice. Characterization of antigens were done, quantitatively (by spectrophotonieter) and qualitatively (by SDS PAGE electrophoresis).The results showed that the titre rate of hookworm larvae antigens was 145 ug/ml. The antigens consist of 4 protein fractions with molecular weight of 25 KD, 55 KD, 66 KD and above 66 KD. Those antigents apparently generated high immune response in immunized miceKey Words; Ancylostoma spp. - CTAB detergent - SDS PAGE electrophoresis - immunology - parasitology

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