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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 61   62   63   64   65 
Efek Teratogenik Sinar X Arif Faisal, Arif Faisal
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 03 (1981)
Publisher : Universitas Gadjah Mada

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Abstract

The application of X-rays in the medical field has positive and negative effects. The effects of X-ray radiation to the intrauterine embryo and foetus depend on the period of gestation. In the first trimester the embryo may be resorbed and aborted and may also be born with serious defects. In the late trimester radiation may cause less serious defects and it may disturb the function of organs. Many defects involve nerve names and are associated with symptoms of mental retardation.To prevent radiation exposure to embryo and foetus, it is necessary to observe the "ten -day rule", when X -ray examination is performed. The threshold doses for embryo and foetus are still unknown.Key Words: physical deformity - mental retardation - radiobiology - radiation injury - teratogenic effect
Ketepatan MESS (mangled extremity severity score) pada penentuan amputasi dini fraktur terbuka tibia tipe III sesuai klasifikasi Gustilo Armis, Armis
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 03 (1996)
Publisher : Universitas Gadjah Mada

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Abstract

The amputation and reconstructive procedure of the management of open tibial fracture type III is still of interest and controversy because the amputation effort is considered as a punishment of primary treatment but a reconstructive method in massive lower extremity trauma is difficult. The MESS is a scoring system that can be applied to mangled extremity and help one determines which mangled limb will eventually come to amputation. The record of 28 open tibial fracture type III patients had been reviewed at the SARDJITO hospital 1990-1995. All seven open tibial fracture type Ill C patients with MESS of greater than seven were amputated. According to four tables of blind comparison analyzing MESS value those patients of more than seven was found to have a positive predictive of 100 % that may be best treated by primary amputation. In conclusion the MESS is an early and accurate predictor for identifying the extremity that may be best treated by amputation or reconstruction.Key words : open fracture - MESS - tibial fracture - amputation - mangled extremity
Penicillin Dalam Pengobatan Infeksi Meningococci Samekto Wibowo, Samekto Wibowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 02 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Banyak obat yang dipakai dalam pengobatan infeksi meningococci, di antaranya ialah penicillin. Obat pilihan bukan saja harus mempunyai effektivitas terhadap microorganismenya, juga harus mempunyai kemampuan masuk dalam cairan cerebrospinal. Inflamasi meninges memperbesar pemasukan obat ke dalam cairan itu.Banyak obat masuk dalam golongan penicillin, tapi semuanya termasuk golongan yang sukar menembus barrier darah-otak. Amoxycillin, suatu preparat penicillin semisynthetis yang baru, mempunyai kemampuan masukdalam cairan cerebrospinal yang lebih besar. lagi bila diberikan secara infus intraveneus yang lambat. Percobaan telah dilakukan pada anjing. Seandainya hal itu juga berlaku pada manusia, tentulah akan sangat menggembirakan.
Drug use in pregnancy and labor Risanto Siswosudarmo, Risanto Siswosudarmo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 02 (1991)
Publisher : Universitas Gadjah Mada

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Abstract

Drug use in pregnancy should consider two main things, the first is its indication to the mother and the second, the more important, is its potential side-effect to the fetus. The aim of this paper is to review the possibility of side-effects of drugs commonly used during pregnancy, labor and delivery.Side-effects of drugs to the fetus are classified into three catagories namely1. embryotoxic effect,2. teratogenic effect and 3. minor side-effect.Embryotoxic effect is the most severe side-effect causing CO the death of the conceptus which usually terminates in early abortion. Teratogenic effect is an effect that causes major congenital anomalies. This effect happens if certain drugs are taken during the phase of organogenesis, i. e. between the third and the eighth week after conception. The minor side-effect may occur if some potential drugs are taken during the fetal period, i. e. during the phase of cellular hypertrophia or after the second month of pregnancy.Based on the teratogenic property of drugs, they can be classified into three major divisions:1. known teratogens such as thalidomide, anticancer drugs, certain hormones, sodium valproate and isotretionine,2. probable teratogens such as anticonvulsant, tobacco, alcohol, lithium, warfarin, and3. possible teratogens such as barbiturate, sulphonamide, certain an timalarials, oral an ndiabetics, LSD, certain antibiotics and some vaccines.The severity of anomalies in the fetus depends on the type of drugs, dosage, phase of fetal development, and species sensitivity. The general rule is all potential teratogenic drugs should be avoided during pregnancy, especially during the first trimester. Drugswith certain teratogenic effect should absolutely not be used during pregnancy, in spite of its indication.Key Words: drugs - pregnancy - teratogens - embryo toxic effects - congenital malformation
Perubahan-Perubahan Segmental pada Pertumbuhan Anak Perempuan Umur 7-10 Tahun di Yogyakarta Adi Soekarto, Adi Soekarto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 01 (1980)
Publisher : Universitas Gadjah Mada

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Abstract

The growth in stature actually consists of segmental growth, because it could be divided into various segments, i. e.: head and neck, trunk, and upper and lower leg. All segments grow independently under their own velocity; the stature is the same as the sum of the length of all segments. The body width also grows at about equalspeed as the trunk.Four samples of girls, between seven to ten years of age, are taken from the collected data in the Department of Physical Anthropology, Gadjah Mada University Faculty of Medicine. The increment of body length is mainly caused by leg length between seven to eight and nine co ten years of age, and by the trunk length between eight to nine years of age.Key Words: segmental growth - stature - Indonesian children - trunk length - leg length
Infection post debridement before and after golden period of open fracture of the lower leg grade Ill A and Ill B. Armis, Armis
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 03 (1995)
Publisher : Universitas Gadjah Mada

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Abstract

All open fractures especially open fracture of the lower leg grade III A and III B, should be assumed to be contaminated, therefore they tend to be infected. The time of intervention is one of the risk factors of infection complication.A descriptive analysis has been conducted aiming at evaluate the occurrence of infection and the time of treatment on patients with open fracture of the lower leg grade III A and III B. In this study 102 cases (80 males and 22 females) who had open fracture of the lower leg grade III A and III B were admitted to Dr. Sardjito General hospital, Yogyakarta. Patients were evaluated according to the inclusion and exclusion criteria. Out of fifty-four cases underwent intervention before 8 hours after injury (within golden period) 25 cases (46,29%) had been infected. The rest (48 cases) who had treatment after 8 hours since trauma, 83,33% (40 cases) were infected.A statistical analysis (X2 = 13,520, df=1 and p < 0,001) showed that there was significant difference of infection complication of open fracture of the lower leg grade III A and III B and the intervention between within and beyond golden period.Key words: open fracture - tibia fracture - infection - golden period - debridement
Oral rehydration solution for maintenance therapy m severe acute gastroenteritis Bambang Sugeng,, Bambang Sugeng,
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 17, No 03 (1985)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Diarrheal disease is one of the main child health problems in Indonesia. Oral Rehydration Solution (ORS) is successfully used in rehydration therapy of mild and moderate dehydration due to acute gastroenteritis. Ringer lactate and ORS are distributed to primary health centres; however, Dextrose Saline or Dextrose 1/2 Saline are not. So far, maintenance therapy in Dr. Sardjito Hospital is done with Dextrose 1/4 Saline or Dextilise 1/2 Saline. The efficacy of maintenance therapy with ORS had been studied from the end of January through August, 1983. Fifiy-seven children suffering from severe dehydration due to acute gastroenteritis were admitted, comprising 29 children as study group and 28 children for control; but 5 children of the study group were excluded because of technical faults. Rehydration therapy was performed with 100 ml/kgBW Ringer lactate-5% glucose together with ORS during 4 hours (50 ml/kgBW during 1 hour and 50 ml/kgBW during the next 3 hours). For the maintenance therapy breast milk or diluted formula and ORS were given. Dextrose— Saline or Dextrose - 1/2 Saline were used for maintenance therapy of the control group. The result of the maintenance therapy in the study group after 24 hours was one case moderate dehydration, 7 cases mild dehydration and 16 cases were rehydrated, whereas in the control group 13 cases mild dehydration and 15 cases were rehydrated. The difference was statistically not significant (p > 0,05). In this study no dehydration was obtained in the following days. It can be concluded that maintenance therapy with ORS on children suffering from severe dehydration due to acute gastroenteritis was succesful after intravenous rehydration with 100 ml/ kgBW solution during 4 hours. Key Words: rehydration - oral rehydration solution - breast milk - diluted formula - diarrhea
Risk factor of hipernatremia in underfive with diarrhea Candra Segeran, Candra Segeran
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 04 (2005)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Oral Rehydration Salt (ORS) solution is known as a leading therapy for diarrhea. For more than 35 year WHO and UNICEF have a single formulation of glucose-based ORS solution to prevent or treat dehydration from diarrhea. The recommended solution which provides a solution containing 90 mmol/L of sodium, 111 mmol/L of glucose with a total osmolarity 311 mOsm/I, has proven effective in wordwide use. It has been contributed substantially to the dramatic global reduction in mortality from diarrhea disease during the period. This solution is more hyperosmolar than plasma, so it can increase the risk of hypernatremia in children, especially if they do not add well as the standard of making the ORS salution. The objective: This study aims to determine whether improper mix of ORS is a risk factor for hypernatremia in children with diarrheaMethods: A case-control study was performed in this study and chi-square and logistic regression were generated in the data analysis. The sample comprised hospitalized children with acute watery diarrhea admitted at Sardjito Hospital between January 181 2002 - July 3181 2005Result: Mortality caused by hypernatremia is found in 13 children (29%) and 77% from the group have natrium level more than 155 mEq/L. Two from 12 children (12%) with Na level more than 155 mEq/L survived.Conclusion: Oral rehydration solution, formula milk, salt-glucose solutionj and dehydration state are the strong risk factors for hypernatremia.Key words: hypernatremia - risk factor - diarrhea - children 
Phimosis post-circumcisi: Laporan Kasus Armies, Armies
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 9, No 03 (1977)
Publisher : Universitas Gadjah Mada

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Abstract

keywords: preputium, kuman anerob, vibrio, spirochetes
Extended Use of a Copper Intrauterine Device Beyond Theoretical Effectiveness: A ten-year study on the Multiload Cu-250 in a ynecologic private practice in Indonesia with specific reference to its use in the national.. R. Soeprono, R. Soeprono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 20, No 01 (1988)
Publisher : Universitas Gadjah Mada

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Abstract

Pemakaian IUD Bertembaga dalam waktu lama melewati masa efektip teoretis tidak mengganggu efektifitasnya untuk mencegah terjadinya kehamilan. Hal ini disimpulkan dari penelitian se-lama sepuluh tahun meliputi 52 pasien praktek spesialis pribadi yang setuju untuk tents menggunakan Multiload Cu-250 tanpa ganti setelah pemakaian selama tiga- tahun yang merupakan batasan masa pakai efektip teoretis bagi jenis IUD Mi. Lama pemakaian tercatat berkisar antara 36,08 sampai 100,51 bulan, sedangkan rata-rata pemakaian adalah 52,10 bulan. Sebanyak 25 (48,07%) wanita memakainya selama 3-4 tahun, 19 (36,53%) selama 4-5 tahun dan 9 (17,30%) selama 6-7 tahun. Pemakaian terlama tercatat pada 4 wanita selama 77,60; 72,48; 92,72 dan 100,51 bulan. Tidak terjadi sate pun kegagalan kehamilan dalam kelompok penelitian ini. Kelompok pembanding terdiri atas 63 wanita pemakai jenis IUD yang sama selama waktu kurang dari tiga tahun dan berasal dad praktek pribadi yang sama. Gangguan subyektip, perdarahan, kelainan haid dan ekspulsi tidak menunjukkan peningkatan frekuensi yang berarti. Sebaliknya, infeksi panggul dan sekresi vaginal yang berlebihan bertambah Bering secara bermakna, meski masih dalam derajat yang ringan dan mudah teratasi. Biqa pula dipahami bahwa terjadi lebih banyak permintaan untuk melepas IUD karena ingin hamil lagi. Karena Multiload Cu-250 sudah terpilihsebagai IUD Bertembaga utama yang digunakan dalam program keluarga berencana nasional di Indonesia, basil penelitian ini dapat bermanfaat dalam kaitannya dengan masalah kontinuasi pemakaian, keamanan, efektifitas, penghematan biaya dan penyediaan peralatan, baik dad segi kepentingan pemakai maupun dari segi kepentingan program. Dalarn penelitian lain yang sedang berjalan hasil-hasil ini akan dibandingkan dengan kelompok pemakai lain yang berganti IUD setelah usai masa efektip teoretis tiga tahun. Dianggap perlu diadakannya penelitian•penelidan lain dalam lingkup epidemiologik lapangan yang lebih Was dengan kondisi klinis medic yang mungkin tidak selalu optimal.Key Words: copper intrauterine device — family planning — Multiload Cu-250 — demography —gynecology

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