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Jurnal Anestesi Perioperatif
Published by Universitas Padjadjaran
ISSN : 23377909     EISSN : 23388463     DOI : 10.15851/jap
Core Subject : Health, Education,
Education Health Professions
Jurnal Anestesi Perioperatif (JAP)/Perioperative Anesthesia Journal is to publish peer-reviewed original articles in clinical research relevant to anesthesia, critical care, case report, and others. This journal is published every 4 months with 9 articles (April, August, and December) by Department of Anesthesiology and Intensive Care Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung.
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Pemberian Magnesium Sulfat Intravena Meningkatkan Efek Analgesia Pascaoperasi pada Bedah Mayor Menggunakan Anestesi Umum Irawan, Hengki; Subagiartha, I Made; Widnyana, I Made Gede
Jurnal Anestesi Perioperatif Vol 2, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Penatalaksanaan nyeri akut pascaoperasi merupakan tugas penting dokter anestesi. Morfin banyak digunakan untuk mengontrol nyeri pascaoperasi. Tujuan penelitian ini untuk mengetahui pengaruh pemberian MgSO4 intravena selama operasi terhadap efek analgesia dan kebutuhan morfin pascaoperasi. Penelitian ini adalah uji klinik blok tersamar ganda. Tiga puluh enam subjek usia 21–55 tahun dialokasikan ke dalam kelompok A yang diberikan MgSO4 30 mg/kgBB intravena 15 menit dilanjutkan 15 mg/kgBB/jam sampai akhir operasi dan kelompok B diberikan NaCl 0,9% dengan volume sama yang menjalani operasi bedah mayor di RSUP Sanglah Denpasar pada Juni–Agustus 2014. Data hasil penelitian dianalisis dengan Uji Mann-Whitney. Nilai visual analog scale (VAS) diam dan bergerak pada jam ke-4 dan ke-8 pada kelompok Mg berbeda bermakna (p<0,05). Perbedaan konsumsi morfin pascaoperasi pada jam ke-4, ke-8, dan ke-24 berbeda bermakna (p<0,05). Simpulan penelitian ini adalah pemberian MgSO4 intravena selama operasi meningkatkan efek analgesia dan menurunkan kebutuhan morfin pascaoperasi.Kata kunci: Analgesia pascaoperasi, anestesi umum, bedah mayor, magnesium sulfatIntravenous Magnesium Sulphate Administration to Improve Post-operative Analgesia Effect in Major Surgery with General AnesthesiaAbstractRelieving acute post-operative pain is an important role of anesthesiologist. Morphine is frequently used to control moderate to severe post operative pain. The objective of this study is to understand the effect of intravenous MgSO4 administration in improving post-operative analgesia effect. This study was a double-blind randomized block clinical trial. The subjects of this study were patients who underwent major surgeries in Sanglah Hospital during the period of June to August 2014. Thirty six subjects age 21–55 years allocated to group A received intravenous MgSO4 30 mg/kgBW intravenous bolus in 15 minutes followed by 15 mg/kgBW/hour until the surgery is finished and group B received NaCl 0.9% with the same volume. Data were then analyzed using  the Mann-Whitney Test. The stationary and mobile VAS scores in the  4th and 8th hour in Mg group were significantly different (p<0.05). Post-operative morphine consumptions in the 4th, 8th, and 24th hour were significantly different between the Mg and NaCl 0.9% groups (p<0.05). It is concluded that the administration of  intravenous MgSO4 during operation increases analgesia effect and reduces post-operative morphine needKey words: General anesthesia, magnesium sulfate, major surgery, post-operative analgesia DOI: 10.15851/jap.v2n3.335
CO2 Gap Sebagai Prediktor Tingkat Mortalitas Pasien Sepsis Berat di Intensive Care Unit Wiraatmaja, Immanuel; Oktaliansah, Ezra; Maskoen, Tinni T.
Jurnal Anestesi Perioperatif Vol 2, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Tingkat mortalitas pasien sepsis berat di Intensive Care Unit (ICU) dihitung dengan menggunakan skor Acute Physiology and Chronic Health Evaluation (APACHE) II dan memerlukan pemeriksaan yang banyak serta kompleks. Peningkatan p (vena-arteri)CO2 (CO2 gap) berhubungan dengan penurunan indeks jantung, karena itu diharapkan CO2 gap memiliki kemampuan untuk menentukan tingkat mortalitas pasien sepsis berat. Penelitian ini bertujuan untuk mengetahui kegunaan CO2 gap sebagai prediktor tingkat mortalitas pasien sepsis berat di ICU Rumah Sakit Dr. Hasan Sadikin (RSHS) Bandung yang lebih mudah serta murah.Penelitian ini dilakukan secara prospektif observasional terhadap 50 orang. Penelitian dilakukan di ICU RSHS Bandung dari bulan Agustus 2013–Januari 2014. Setiap subjek penelitian diperiksa nilai CO2 gap. Subjek dibagi ke dalam 2 kelompok berdasarkan nilai CO2 gap menjadi kelompok nilai CO2gap tinggi (nilai CO2 gap ≥6) dan nilai CO2 gap  rendah (nilai CO2 gap<6). Penilaian ulang dilakukan pada hari ke-28 untuk masing-masing kelompok untuk menilai adakah pasien dalam kelompok tersebut yang meninggal. Hasil penelitian menunjukan bahwa CO2 gap memiliki sensitivitas 94,7%; spesifisitas 90,3%; positive predictive value 85,7%; negative predictive value 96,5%; likelyhood ratio positive CO2 gap 9,76; dan likelyhood ratio negative CO2 gap adalah 0,05. Simpulan penelitian adalah CO2 gap dapat digunakan untuk melakukan prediksi tingkat mortalitas pasien sepsis berat.Kata kunci: CO2 gap, mortalitas, sepsisCO2 Gap as a Mortality Incidence Predictor for Severe Sepsis Patient  in Intensive Care Unit The mortality rate of severe sepsis patients in Intensive Care Unit (ICU) is measured by using the Acute Physiology and Chronic Health Evaluation (APACHE) II score, which need various complex examinations. Increased p(venous-arterial) CO2(CO2 gap) relates to decreased cardiac index; therefore, it is expected that CO2 gap can be used to predict mortality incidence in severe sepsis patients in the ICU of Dr. Hasan Sadikin General Hospital (RSHS).This study was a prospective study on 50 patients who met severe sepsis criteria conducted in the ICU of RSHS Bandung from August 2013 to January 2014. The CO2 gap was be measured in all the patients. Subjects were divided into two groups according to the CO2 gap value, i.e. high CO2 gap (≥6) and low CO2 gap (<6). Subjects were then assessed on the 28th day to observe the mortality incidence the respective group. It was shown that a CO2 gap value had a sensitivity of 94.7%, specificity of 90.3%, positive predictive  value of 85.7%, and the negative predictive value of 96.5%. The likelihood ratio of  positive CO2 gap  and negative CO2 gap were 9.76 and 0.05, respectively. In conclusion, CO2 gap can be used to predict the mortality incidence in severe sepsis patients in the ICU of RSHS Bandung. Key words: CO2 gap, mortality, sepsis DOI:10.15851/jap.v2n3.331
Perbandingan Pemberian Parecoxib Na 40 mg Intravena Preoperatif dengan Pascaoperatif dalam Penatalaksanaan Nyeri Pascaoperatif pada Operasi Laparotomi Ginekologis Anom Yuswono, Ardhana Risworo; Maskoen, Tinni T.; Fuadi, Iwan
Jurnal Anestesi Perioperatif Vol 2, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Multimodal analgesia dan preemptive analgesia menjadi terapi yang efektif dalam penatalaksanaan nyeri pascaoperatif. Tujuan penelitian ini adalah untuk menganalisis perbandingan pemberian parecoxib Na 40 mg intravena preoperatif dengan pascaoperatif terhadap nilai NRS. Penelitian ekperimental dengan rancangan analisis komparatif dilaksanakan dari Maret–Juni 2013. Subjek adalah wanita usia 18-60 tahun yang menjalani operasi laparatomi ginekologis dengan anestesi umum di Rumah Sakit Dr. Hasan Sadikin Bandung. Subjek terdiri atas 18 orang pada masing masing kelompok. Parecoxib Na 40 mg diberikan pada dua kelompok perlakuan, yaitu pre atau pascaoperatif. Tramadol 200 mg diberikan pascaoperatif pada semua kelompok dan dilakukan penilaian NRS di ruang pemulihan. Nilai NRS 1 lebih banyak ditemukan pada kelompok I, nilai NRS 3 lebih banyak didapatkan pada kelompok II. Nilai NRS pada kelompok I didapatkan nyeri ringan 15 orang dan nyeri sedang 3 orang. Pada kelompok II didapatkan nyeri ringan 15 orang dan nyeri sedang 3 orang, berdasarkan analisis uji chi-kuadrat tidak terdapat perbedaan nilai NRS kedua kelompok. Tidak didapatkan subjek yang memerlukan analgetik tambahan. Simpulan penelitian ini adalah bahwa tidak terdapat perbedaan antara pemberian parecoxib Na 40 mg preoperatif dan pascaoperatif dalam penatalaksanaan nyeri pascaoperatif. Efek analgetik yang lebih baik didapatkan pada pemberian parecoxib Na preoperatif dengan nilai NRS yang lebih rendah. Kata kunci: Laparatomi ginekologis, numerical rating scale, parecoxib Na, preoperatif, pascaoperatifComparison of Pre-operative and Post-operative Intravenous 40 mg Parecoxib Na in Gynecologic Laparatomy Surgery Post-Operative Pain Management AbstractMultimodal analgesia regimens  and preemptive analgesia will improve post- operative  pain relief. The purpose of this study was to compare pre- and post- operative parecoxib 40 mg intravenous to NRS value. This experimental study with comparative analytical method was conducted in women 18 to 60 years old who underwent gynecologic laparatomy at Dr. Hasan Sadikin General Hospital Bandung during the period of March to June 2013. Subjects consisted of 18 women for each pre-operative and post-operative group. Parecoxib 40 mg were given to the two groups, pre-operative (group I) and post-operative (group II), while intravenous tramadol 200 mg was also also given to all groups post-operatively. The NRS was calculated at recovery room. NRS value 1 was more frequent in group I while the NRS value 3 more frequent in group II. NRS values  in group I: 15 with mild pain (83.3%), 3 with moderate pain (16.7%). In group II the values were 15 with mild pain (83.3%), 3 with moderate pain (16.7%), which was not significant. In conclusion, there is no difference between pre-operative and post-operative parecoxib sodium 40 mg for post operative pain management. There is a better analgetic effect in the group with pre-operative parecoxib which is apparent from lower NRS.Key words: Gynecological laparatomy, numerical rating scale, parecoxib Na, post operative, pre operative DOI: 10.15851/jap.v2n3.327
Efektivitas Pemberian Cairan Praoperatif Ringer Laktat 2 mL/kgBB/jam Puasa untuk Mencegah Mual Muntah Pascaoperasi Wijaya, Andi Ade; Fithrah, Bona A.; Marsaban, Arif H. M.; Hidayat, Jefferson
Jurnal Anestesi Perioperatif Vol 2, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Teknik nonfarmakologi yang dapat dilakukan untuk menurunkan angka kejadian mual muntah pascaoperasi adalah pemberian cairan praoperatif. Tujuan penelitian ini untuk mengetahui efektivitas pemberian cairan praoperatif Ringer laktat 2 mL/kgBB/jam puasa untuk menurunkan angka kejadian mual muntah pascamastektomi. Penelitian ini merupakan uji klinis acak yang dilakukan pada bulan Maret–April 2013 di Rumah Sakit Kanker Dharmais, Rumah Sakit Persahabatan, Rumah Sakit Fatmawati, dan Rumah Sakit Cipto Mangunkusumo Jakarta, pada pasien status fisik American Society of Anesthesiologist (ASA) 1–2. Sebanyak 102 pasien diacak ke dalam kelompok hidrasi dan kelompok kontrol. Analisis data dilakukan menggunakan uji chi-kuadrat. Terdapat perbedaan yang signifikan dalam kejadian mual pada 0–1 jam pascaoperasi (kelompok hidrasi 20% vs kelompok kontrol 39%) dan pada 0–24 jam pascaoperasi (kelompok hidrasi 22% vs kelompok kontrol 41%). Walaupun tidak berbeda secara statistik, angka kekerapan mual pada 1–24 jam pascaoperasi lebih rendah pada kelompok hidrasi 12% (6) dibandingkan dengan kelompok kontrol 23% (12). Tidak ada perbedaan secara statistik pada angka kekerapan muntah di kedua kelompok penelitian. Pemberian cairan praoperatif Ringer laktat 2 mL/kgBB/jam puasa efektif untuk menurunkan angka kejadian mual pascaoperasi mastektomi pada 1 jam pertama pascaoperasi.  Kata kunci: Cairan praoperatif, mastektomi, mual muntah pascaoperasi Effectiveness of Pre-operative Lactated Ringer’s Solution 2 mL/kgBW/h in Fasting Patients to Prevent Post-operative Nausea and Vomiting Non pharmacologic approaches to overcome post operative nausea and vomiting include giving pre-operative hydration. The objective of this study was to learn the efficacy of pre-operative lactated Ringer’s solution (2 mL/kgBW/hour) in fasting patients to overcome the post-operative nausea and vomiting in mastectomy surgery. This study was a randomized clinical trial that conducted in March to April 2013 in Dharmais Hospital-National Cancer Center,  Persahabatan Hospital, Fatmawati Hospital, and Rumah Sakit Cipto Mangunkusumo Jakarta to patients with  American Society of Anesthesiologist (ASA) physical status 1–2. A total of 102 patients were randomized into the hydration group and control group. Data analysis was performed using chi-square test or appropriate test using SPSS ver. 15. There were statistically significant differences in the incidence of nausea at 0–1 hour post-operative (19.6% in hydration group vs. 39.2% in control group) and at 0–24 hours post-operative (21.6% in hydration group vs. 41.2% control group). The incidence of 1–24 hours PONV, although not statistically significant, was higher in the control group (11.8% in hydration group vs. 23.5% in control group). There was no difference in vomiting incidence between the two groups. Pre-operative lactated Ringer’s solution 2 mL/kgBW/hour in fasting patients effectively reduces the incidence of post-operative nausea one hour after operation. Key words: Mastectomy, post-operative nausea and vomiting pre-operative hydration DOI: 10.15851/jap.v2n3.332
Hubungan Lima Parameter Kraniofasial dengan Skor Cormack-Lehane pada Anak Indonesia Usia 4–12 Tahun Kapuangan, Christoper; Tanod, Jemmy Wilson; Wijaya R., Andi Ade; Soenarto, Ratna Farida
Jurnal Anestesi Perioperatif Vol 2, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Penilaian jalan napas sangat penting dilakukan, terutama pada pasien anak. Pedoman yang ada pada dewasa tidak dapat dipakai pada populasi pediatri. Tujuan penelitian ini untuk mengetahui hubungan antara lima ukuran parameter kraniofasial dan skor Cormack-Lehane pada populasi anak usia 4–12 tahun di Indonesia. Penelitian ini bersifat observasional analitik yang dilakukan di Rumah Sakit Dr. Cipto Mangunkusumo Jakarta dari Maret sampai September 2013. Pengumpulan data dilakukan secara berurutan pada 134 pasien yang menjalani anestesia umum. Pengukuran dilakukan dari jarak tepi bawah bibir ke ujung mentum, jarak angulus mandibula ke ujung mentum, jarak tragus telinga ke sudut bibir, jarak mentohioid dan jarak antara angulus mandibula kanan dan kiri. Tingkat kesulitan laringoskopi dinilai menggunakan skor Cormack-Lehane, kemudian dibagi menjadi mudah dan sulit. Analisis data dilakukan menggunakan Uji Mann-Whitney dan uji-t tidak berpasangan untuk mencari hubungan antara lima parameter tersebut dan skor Cormack-Lehane. Penelitian ini tidak mendapatkan hubungan yang bermakna antara semua parameter kraniofasial di atas dan skor Cormack Lehane (nilai p berturut adalah 0,349; 0,638; 0,499; 0,765; dan 0,301). Simpulan, pada populasi anak Indonesia usia 4–12 tahun, lima parameter kraniofasial tidak dapat digunakan untuk prediksi kesulitan visualisasi laring.Kata kunci: Jalan napas, parameter kraniofasial, pediatri, skor Cormack-LehaneAssociation between Five Craniofacial Parameters and Cormack-Lehane Score in 4 to 12 Years-old Indonesian Paediatric Patients AbstractAirway assessment is very important, especially in pediatric patients. Adult airway guidelines can not be applied to pediatric population. The aim of this study was to determine the association between five craniofacial parameters and the Cormack-Lehane scores in 4 to 12 year-old Indonesian pediatric patients. This was an observational analytic study conducted in RSUPN Cipto Mangunkusumo from March to September 2013. Data were collected consecutively on 134 patients who underwent general anesthesia. The distance of the lower lip to mentum, mandibular angle to mentum, ear tragus to mouth, mentohyoid distance and distance of left and right mandibles were measured. Laryngoscopic difficulty levels were assessed using Cormack-Lehane score and divided into two groups: easy and difficult. Data analysis was performed using the Mann-Whitney Test and unpaired t-test to find the association between those five parameters and the Cormack-Lehane score. This study did not find any significant relationshis between all craniofacial parameters above and Cormack Lehane scores (p values: 0.349, 0.638, 0.499, 0.765, and 0.301 respectively). We concluded that in Indonesian pediatric population aged 4 to 12 years, the five craniofacial parameters cannot be used to predict laryngeal visualization.Key words: Airway, pediatric, Cormack-Lehane score DOI: 10.15851/jap.v2n3.328
Letak Conus Medularis terhadap Vertebra Menggunakan Hasil Pencitraan Magnetic Resonance Imaging di Rumah Sakit Dr. Hasan Sadikin Bandung untuk Anestesi Spinal Nurfitriani, -; Nawawi, Abdul Muthalib; Yadi, Dedi Fitri; Anwary, Farhan
Jurnal Anestesi Perioperatif Vol 2, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Kepentingan dari conus medularis bagi dokter spesialis anestesi adalah saat dilakukan tindakan anestesi spinal yang memiliki risiko terjadi trauma medula spinalis yang serius. Conus medularis dapat diidentifikasi melalui hasil pencitraan magnetic resonance imaging (MRI). Penelitian yang dilakukan sekarang bertujuan untuk mengetahui distribusi letak ujung conus medularis pada orang Indonesia secara observasional deskriptif dengan menggunakan hasil pencitraan magnetic resonance imaging (MRI) lumbosakral. Penelitian dilakukan melalui pemeriksaan terhadap letak ujung conus medularis secara retrospektif pada 135 hasil pencitraan MRI pasien usia 18–65 tahun dari bulan Januari 2013 hingga Maret 2014 di Departemen Radiologi Rumah Sakit Dr. Hasan Sadikin Bandung. Dari penelitian ini didapatkan letak ujung conus medularis paling banyak berada setinggi sepertiga tengah L1, dengan rentang mulai dari setinggi sepertiga tengah T12 hingga sepertiga bawah L2. Berdasarkan parameter jenis kelamin didapatkan distribusi letak conus medularis pada perempuan cenderung lebih kaudal dibandingkan dengan laki-laki.Kata kunci: Conus medularis, magnetic resonance imaging, orang IndonesiaDetermination of Conus Medullaris Position within the Vertebra using Magnetic Resonance Imaging in Dr. Hasan Sadikin General Hospital Bandung for Spinal Anesthesia PurposeAbstractThe position of conus medullaris is important to be identified by anesthesiologists during spinal anesthesia to avoid serious spinal cord trauma risk. Conus medullaris can be accurately identified through magnetic resonance imaging (MRI) images. The aim of this study was to determine the distribution of conus medullaris in Indonesians through a descriptive observation using magnetic resonance imaging (MRI) images of lumbosacral. The locations of conus medullaris were observed retrospectively on 135 MRI images scanned, aged 18–65 years, during the period of January 2013 to March 2014 at the Departement of Radiology, Dr. Hasan Sadikin General Hospital Bandung. From this study, it was revealed that the conus medullaris are mostly located at the middle third of L1, ranging from the middle third of T12 to the lower third of L2. With gender as a parameter, it was shown that the distribution of conus medullaris in women tends  to be more caudal than in men.Key words: Conus medullaris, Indonesian, magnetic resonance imaging DOI: 10.15851/jap.v2n3.333
Prevalensi dan Faktor Risiko Nyeri Punggung Bawah di Lingkungan Kerja Anestesiologi Rumah Sakit Dr. Hasan Sadikin Bandung Patrianingrum, Meilani; Oktaliansah, Ezra; Surahman, Eri
Jurnal Anestesi Perioperatif Vol 3, No 1 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Nyeri punggung bawah (NPB) merupakan masalah kesehatan yang banyak dialami oleh tenaga kesehatan. Tujuan penelitian ini untuk mengetahui prevalensi dan faktor risiko nyeri punggung bawah di lingkungan kerja anestesiologi dan terapi intensif Rumah Sakit Dr. Hasan Sadikin (RSHS) Bandung. Penelitian ini merupakan penelitian deskriptif dengan rancangan studi potong silang. Subjek penelitian meliputi seluruh peserta pendidikan dokter spesialis (PPDS) dan konsulen anestesiologi di RS Dr. Hasan Sadikin Bandung periode bulan April─Juni 2014. Analisis data dilakukan dengan uji chi-kuadrat, Eksak Fisher dan Kolmogorov Smirnov. Hasil penelitian menunjukkan bahwa prevalensi nyeri punggung bawah yang timbul setelah masuk dalam lingkungan kerja anestesiologi di RSHS adalah 35,7%. Faktor risiko yang signifikan adalah kebiasaan merokok (RR 1,35)  dan kurang olahraga (RR 80,04). Faktor posisi saat melakukan tindakan anestesi signifikan menimbulkan nyeri punggung bawah. Simpulan, prevalensi nyeri punggung bawah setelah masuk lingkungan kerja anestesiologi RSHS Bandung adalah 35,7% dengan faktor risiko adalah merokok dan kurang olahraga. Faktor posisi selama melakukan tindakan anestesi bersama-sama dengan faktor risiko lain mungkin turut memperberat nyeri punggung bawah. Kata kunci: Anestesi, faktor risiko, nyeri punggung bawah, prevalensiPrevalence and Risk Factors of Lower Back Pain in the Anesthesiology Workplace in Dr. Hasan Sadikin General Hospital BandungAbstractLower back pain (LBP) is a common health problem in many health professionals. The purpose of this study was to determine the prevalence and risk factors causing lower back pain in the anesthesiology workplace at Dr. Hasan Sadikin Hospital General Bandung. This research is a descriptive study with cross-sectional design. Subjects on this research were the anesthesiology residents and consultants in Dr. Hasan Sadikin General Hospital Bandung between April and June 2014. Data analysis was performed by chi-square, Exact Fisher and Kolmogorov Smirnov. The results showed that the prevalence of lower back pain that arises after entering the anesthesiology workplace in Dr. Hasan Sadikin General Hospital Bandung was 37.5%. The significant risk factors were smoking (RR 1.348)  and lack of exercise (RR 80.04) while the position factor during conducting anesthesia did not significantly cause lower back pain. The conclusions of this study indicate that the prevalence of low back pain that arises after entering the anesthesiology and intensive therapy workplace in Dr. Hasan Sadikin General Hospital Bandung is 37.5%.  In addition, the risk factors that significantly cause lower back pain in the anesthesiology and intensive therapy workplace in Dr. Hasan Sadikin General Hospital Bandung were smoking and lack of exercise. The position factor during conducting anesthesia together with other risk factors may contribute to the arising of lower back pain. Key words: Anesthesia, lower back pain, prevalence, risk factors DOI: 10.15851/jap.v3n1.379  
Perbandingan Efek Pemberian Norepinefrin Bolus Intravena dengan Norepinefrin Infus Kontinu dalam Tatalaksana Hipotensi, Laju Nadi, dan Nilai APGAR pada Seksio Sesarea dengan Anestesi Spinal Sumardi, Fitri Sepviyanti; Nawawi, Abdul Muthalib; Maskoen, Tinni T.
Jurnal Anestesi Perioperatif Vol 3, No 1 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Vasopresor sering digunakan dalam tatalaksana hipotensi anestesi spinal pada seksio sesarea. Penelitian bertujuan membandingkan efek pemberian norepinefrin bolus intravena dengan norepinefrin infus kontinu dalam tatalaksana hipotensi pada anestesi spinal pasien seksio sesarea dan pengaruh pada laju nadi serta nilai APGAR. Penelitian bersifat eksperimental acak tersamar ganda pada 44 ibu hamil status fisik American Society of Anesthesiologist (ASA) II yang menjalani seksio sesarea dengan anestesi spinal di Rumah Sakit Dr. Hasan Sadikin Bandung pada September–November 2013. Subjek penelitian dibagi menjadi 2 kelompok yaitu kelompok  norepinefrin bolus intravena 4 µg (NB) dan kelompok norepinefrin infus kontinu 8 µg/menit (NK). Data dianalisis dengan uji-t, Uji Mann-Whitney, chi-kuadrat dan uji-t analysis of variance (ANOVA), nilai p<0,05 dianggap bermakna. Hasil penelitian menunjukkan bahwa peningkatan tekanan darah sistol, diastol, dan rata-rata lebih tinggi pada kelompok NB (p=0,000). Perubahan laju nadi secara umum pada kedua kelompok relatif stabil dan nilai APGAR menunjukkan perbedaan yang tidak bermakna (p>0,05). Simpulan penelitian ini adalah kedua cara pemberian norepinefrin ini dapat digunakan dalam tatalaksana hipotensi anestesi spinal tanpa memengaruhi laju nadi dan nilai APGAR.   Kata kunci: Anestesi spinal, hipotensi, nilai APGAR, norepinefrin, seksio sesareaEffect of Intravenous Norepinephrine Bolus and Norepinephrine Continuous Infusion on Hypotension Management, Heart Rate, and APGAR Score in Caesarean Section Patient under Spinal AnesthesiaAbstractVasopresors are commonly used for the treatment of hypotension in spinal anesthesia for cesarean section. This research aimed to compare intravenous bolus of norepinephrine to continuous infusion of norepinephrine effectiveness in hypotension management in caesarean section patient under spinal anesthesia and their effect on heart rate and APGAR Score, The experimental study was conducted in a double-blind randomized manner to 44 American Society of Anesthesiologist (ASA) physical status II pregnant women undergoing cesarean section with spinal anesthesia in Dr. Hasan Sadikin General Hospital Bandung within the period of September to -November 2013. The Study  subjects were grouped into two groups, the first group received 4 µg intravenous bolus of norepinephrine group (NB) and and the second received 8 µg/minute continuous infusion of norepinephrine group (NK).  Data were analyzed by t-test, Mann-Whitney test, chi-square and analysis of variance (ANOVA) t-test with p<0.05 was considered significant. The results showed that the increase in systolic, diastolic and mean arterial blood pressures were higher in the NB group (p=0.000). Changes in heart rate were generally relatively stable in both groups and APGAR score showed a non-significant difference (p>0.05). Conclusion from this study is the administration of norepinephrine in both ways can be used for the treatment of hypotension of spinal anesthesia without affecting the heart rate and APGAR scoreKey words: APGAR score, caesarean section, hypotension, norepinephrine, spinal anaesthesia DOI: 10.15851/jap.v3n1.375  
Perbandingan antara Sevofluran dan Enfluran terhadap Kontraksi Uterus, Jumlah Perdarahan, dan Skor APGAR pada Seksio Sesarea Elektif Resvita, RR. Pramada; Redjeki, Ike Sri; Bisri, Tatang
Jurnal Anestesi Perioperatif Vol 3, No 1 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Anestetika volatil memiliki sifat fisikokimia yang berbeda-beda yang akan memberikan pengaruh berbeda juga terhadap kontraksi uterus,  jumlah perdarahan dan skor APGAR. Tujuan penelitian ini adalah menilai perbedaan pengaruh antara sevofluran dan enfluran terhadap kontraksi uterus, jumlah perdarahan, dan skor APGAR. Penelitian ini adalah randomized controlled trial (RCT) pada 36 pasien seksio sesarea elektif di Rumah Sakit Melinda pada Juni–Agustus 2011. Pasien dibagi dalam dua kelompok: kelompok I (sevofluran) dan kelompok II (enfluran). Analisis data hasil penelitian dilakukan dengan melakukan uji-t,  Fisher’s Exact Test, dan Uji Mann-Whitney. Hasil penelitian menunjukkan bahwa kontraksi uterus lebih baik pada kelompok sevofluran (p<0,05) dan jumlah perdarahan lebih sedikit pada kelompok sevofluran (p<0,05). Tidak didapatkan perbedaan yang signifikan untuk skor APGAR (p>0,05). Simpulan penelitian ini adalah kontraksi uterus pada seksio sesarea dengan sevofluran lebih baik dibandingkan dengan enfluran dan jumlah perdarahan lebih sedikit pada sevofluran. Skor APGAR pada kedua kelompok tidak menunjukkan perbedaan.Kata kunci: Enfluran, jumlah perdarahan, kontraksi uterus (LAS), seksio sesarea, sevofluran, skor APGARComparison between Sevoflurane and Enflurane Effects on Uterine Contraction, Amount of Bleeding, and APGAR Score in Elective Caesarean SectionAbstractDifferent volatile agents with different physicochemical properties affect uterine contraction, amount of bleeding, and APGAR score in different ways. The objective of this study was to evaluate the effects of different volatile agents, i.e., sevoflurane and enflurane, on  uterine contraction, amount of bleeding, and APGAR score. A randomized controlled trial (RCT) was conducted on 36 patients undergoing elective caesarean section. These patients were randomly divided into two groups, group I (sevoflurane) and group II (enflurane). The data were analyzed using t-test, Mann-Whitney, and fisher exact tests. The result of this study showed that there was a significant difference in the strength of uterine contraction among the sevoflurane group and the enflurane group (p<0.05) and also a significant difference in the amount of bleeding among the two groups (p<0.05), with better results seen ion the sevoflurane group. However, there was no significant difference found oin the APGAR score among the two groups. It is concluded in this study that sevoflurane gives better results in terms of uterine contraction with less bleeding compared to the enflurane group. No difference is found in the APGAR score in sevoflurane and enflurane groups.Key words: Amount of bleeding,  APGAR score, caesarean section, enflurane, sevoflurane, uterine contraction (LAS) DOI: 10.15851/jap.v3n1.381  
Perbandingan Penambahan Klonidin Intratekal 15 µg dan 30 µg pada 12,5 mg Bupivakain 0,5% terhadap Kejadian Menggigil Pascaanestesi Spinal pada Seksio Sesarea Yusup Mansur, Iman Muhammad; Pradian, Erwin; Bisri, Tatang
Jurnal Anestesi Perioperatif Vol 3, No 1 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Menggigil pascaanestesi spinal merupakan efek samping yang sering terjadi. Penelitian ini bertujuan untuk membandingkan penambahan klonidin intratekal antara 15 µg dan 30 µg pada 12,5 mg bupivakain. Penelitian adalah eksperimental dengan uji klinis rancangan acak lengkap terkontrol buta tunggal pada 80 wanita yang menjalani seksio sesarea dengan anestesi spinal,  status fisik American Society of Anesthesiologist (ASA) II, berusia 18–42 tahun, dibagi secara random menjadi dua kelompok, kelompok I menggunakan 12,5 mg bupivakain 0,5 % dan klonidin 15 µg, sedangkan kelompok II mendapat penambahan klonidin 30 µg. Penelitian dilakukan di Rumah Sakit Dr. Hasan Sadikin Bandung pada periode Oktober–Desember 2011. Perbandingan proporsi kejadian kedua kelompok dianalisis secara statistik menggunakan uji chi-kuadrat, sedangkan derajat menggigil dengan Uji Mann-Whitney. Hasil penelitian menunjukkan bahwa kejadian menggigil pascaanestesi pada kelompok II sebanyak 2 pasien, sedangkan pada kelompok I adalah 10 pasien. Simpulan, penambahan klonidin intaratekal 30 µg pada bupivacain 0,5% untuk mencegah menggigil pascaanestesi spinal lebih baik dibandingkan dengan klonidin intratekal 15 µg. Kata kunci: Klonidin intratekal, menggigil pascaanestesi, mencegah menggigil, suhu intiComparison of  15 µg  and 30 µg Intrathecal Clonidine in 12.5 mg 0.5% Bupivacain for Post Spinal Anesthesia Shivering in Caesarean SectionAbstractShivering is a frequently experienced side effect of post-subarachnoid block. This study aimed to determine the which of 15 µg  dose and 30 µg dose of intrathecal Clonidine is better prevents Post anaesthesia shivering. The research was conducting by clinical trials of a single blind randomized controlled design. Eighty pregnant female patients with ASA physical status II, aged 18–42 years, who underwent a caesarean section were randomly divided into two groups, spinal anesthesia performed by using 12.5 0.5% mg bupivacain and 15 µg clonidine in Group I and the same dose of bupicavain but with 30 µg clonidine in group II. The incidence proportion of both groups were statistically compared using chi square test, while the degree of shivering was analyzed using Mann-Whitney test. The results showed that the characteristics of patient data and the core temperature did not statistically different between the two groups. The incidence and degree of shivering were different between the two groups,  with were 2 patients experienced shivering incidence in group II and 10 patients experienced the incidence in group I. It is concluded that the addition of intrathecal 30 µg clonidine to 0.5% bupivacain prevents post-subarachnoid spinal block shivering better than in trathecal clonidine 15 µg.   Key words: Core temperature, intrathecal clonidine post anaesthesia shivering, prevent shivering

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