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Contact Name
Armeida Dwi Ridhowati Madjid
Contact Email
armeida@uin-malang.ac.id
Phone
+6281233402334
Journal Mail Official
alchemy@uin-malang.ac.id
Editorial Address
Fakultas Sains dan Teknologi Universitas Islam Negeri (UIN) Maulana Malik Ibrahim Malang Gedung BJ Habibie Lt 2 Jl. Gajayana 50 Malang 65144 Indonesia
Location
Kota malang,
Jawa timur
INDONESIA
Alchemy : Journal of Chemistry
ISSN : 20861710     EISSN : 24606871     DOI : http://dx.doi.org/10.18860/al
ALCHEMY: Journal of Chemistry (eISSN 2460-6871) is a scientific journal that focus on chemistry. This journal publishes a scientific article that cover research and review articles. Research topics for this journal such as natural science, physical chemistry, inorganic chemistry, organic chemistry, environment, biochemistry, marine, energy and other related-sciences. ALCHEMY: Journal of Chemistry also accepts article about halal products and chemistry on Islamic perspectives.
Articles 208 Documents
Comparison of Antioxidant Activity Testing of Rosemary Leaves Using the DPPH Method Ardian, Muhammad Nur; Wahyuningsih, Sri; Sudarni, Dyan Hatining Ayu
ALCHEMY:Journal of Chemistry Vol 13, No 2 (2025): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v13i2.36316

Abstract

The ability of rosemary leaf extract to scavenge free radicals was tested using the DPPH method in this research. Rosemary leaves were selected based on their natural richness in antioxidant compounds such as polyphenols and flavonoids. The test results showed that the ethanol extract, ethyl acetate fraction, and n-hexane fraction all exhibited very strong antioxidant potential, with  values below 50 ppm. The ethanol extract was the most potent with an IC₅₀ of 23.98 ppm, followed by the ethyl acetate fraction with an  of 26.60 ppm and the n-hexane fraction with an  of 27.95 ppm. The superiority of the ethanol extract is attributed to its ability as an optimal polar solvent for dissolving phenolic compounds. These compounds play a crucial role in stabilizing free radicals through hydrogen/electron donation, as well as resonance mechanisms.
Adsorption of Ciprofloxacyn by Plate-Like Bi4Ti3O12 Manunggal, Pinky Lintang Satriani; Prasetyo, Anton
ALCHEMY:Journal of Chemistry Vol 13, No 2 (2025): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v13i2.36708

Abstract

Antibiotic compound waste has attracted significant attention because of its harmful effects on aquatic environments. One of the methods reported as a potential approach for antibiotic wastewater treatment is adsorption. Bi4Ti3O12 is a triple-layer Aurivillius compound reported to exhibit adsorption properties, although research remains limited. Therefore, we synthesized plate-like Bi4Ti3O12 using the molten salt method. The adsorption test results showed that Bi4Ti3O12 reduced ciprofloxacin concentration by ~51% within 120 minutes. It shows that Bi4Ti3O12 has the excellent capability to adsorb the antibiotic compound ciprofloxacin. Keywords: Ciprofloxacin, Adsorption, Bi4Ti3O12
Edible Film Application of Mung Bean Starch with the Addition Glycerol as a Button Mushrooms Packer Firdausi, Karima Mumtaz; Sedyadi, Endaruji; Rahmayanti, Maya; Warsito, Gita Miranda
ALCHEMY:Journal of Chemistry Vol 13, No 2 (2025): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v13i2.31684

Abstract

The research on the production of edible films from mung bean starch with the addition of glycerol as packaging for button mushrooms aims to analyze the effect of varying glycerol concentrations on the physical and mechanical properties of the edible film, as well as the shelf life of button mushrooms in terms of weight loss. The stages of this research include the production of mung bean starch, the creation of edible films, characterization of the starch and edible films, and their application to button mushrooms using weight loss tests. The edible films were made with glycerol concentrations of 6.3%, 12.6%, and 18.9% of the total starch weight used. The results showed that the edible films at each glycerol variation exhibited a reduction in weight loss that was generally lower compared to the weight loss of the control button mushrooms.
Structural, Optical, and Photocatalytic Properties of Sol–Gel-Derived ZnO Nanoparticles for Methylene Blue Degradation Maria Luruk Seran; Matius Stefanus Batu; Cindy Claudia Christanti; Didi Prasetyo Benu
ALCHEMY:Journal of Chemistry Vol 14, No 1 (2026): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v14i1.40636

Abstract

Zinc oxide (ZnO) nanoparticles are attractive photocatalysts due to their wide band gap, chemical stability, and nanoscale-dependent properties. Herein, ZnO nanoparticles were synthesized and systematically characterized to correlate their structural and optical properties with photocatalytic performance. Raman spectroscopy and X-ray diffraction confirmed the formation of a single-phase wurtzite ZnO structure with high crystallinity. UV–Vis diffuse reflectance spectroscopy revealed a distinct absorption edge in the UV region, and the optical band gap was determined to be 3.07 eV using the Kubelka–Munk–Tauc method. The photocatalytic activity of the synthesized ZnO was evaluated via methylene blue degradation under UV irradiation. Time-resolved UV–Vis absorption measurements showed a gradual decrease in the characteristic absorption peak at 660–670 nm, indicating effective dye degradation. A photocatalytic degradation efficiency of 60.55% was achieved after 150 min of irradiation. Kinetic analysis demonstrated that the degradation process followed pseudo-first-order kinetics with an apparent rate constant of 0.0062 min⁻¹. These results demonstrate that the synthesized ZnO nanoparticles exhibit efficient UV-driven photocatalytic activity, highlighting their potential for nanoscale photocatalyst applications. The structure–property–performance correlation established in this work provides insight for further nanostructure and defect engineering strategies to enhance photocatalytic efficiency.
Analisis Komputasi Inhibitor DGAT dengan Model QSAR Menggunakan Deskriptor RDKit dan XGBoost Algafari Bakti Manggara
ALCHEMY:Journal of Chemistry Vol 14, No 1 (2026): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v14i1.40626

Abstract

Diacylglycerol acyltransferase (DGAT) is a key therapeutic target for metabolic diseases. This study aims to develop a robust Quantitative Structure-Activity Relationship (QSAR) model to predict the activity of DGAT inhibitors using a computational approach. A dataset of 197 DGAT inhibitors with pIC50 values was curated from the ChEMBL database. Molecular descriptors were calculated using RDKit, followed by feature selection through the elimination of zero-variance descriptors and correlation analysis (threshold r 0.80), resulting in 41 representative descriptors for modeling. A predictive model was built using the Extreme Gradient Boosting (XGBoost) algorithm. Model evaluation demonstrated excellent performance with a coefficient of determination (R²) of 0.885 on training data and 0.758 on test data, alongside low RMSE and MAE values. Feature importance analysis revealed that NOCount and MaxPartialCharge descriptors were the most significant contributors to inhibitory activity, providing valuable insights for rational drug design. Although the model showed high predictive accuracy, a negative Q² from cross-validation indicates a need for further optimization. In conclusion, this study successfully demonstrates that the integration of RDKit descriptors and the XGBoost algorithm can yield an accurate and interpretable QSAR model to accelerate the insilico discovery of DGAT inhibitors.
Removal of Methylene Blue from Aqueous Solution with Silica Gel Extracted from Coal Fly Ash Melvi Muharmi
ALCHEMY:Journal of Chemistry Vol 14, No 1 (2026): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v14i1.37926

Abstract

The textile industry has the potential to cause water pollution due to dye waste such as methylene blue (MB). Many methods have been developed to overcome the challenges of dye removal, one of which is the adsorption method. This study introduces silica gel (SiG) as an effective material for MB dye wastewater treatment. The silica source was extrated from coal fly ash (FAC) which has a relatively high silica content, making it a potential silika source for silica gel synthesis. The silica gel formed was characterized using FTIR and SEM. The characterization results showed the presence of silanol and siloxane groups in the synthesized SiG. the morphology of SiG was spherical, non-agglomerated with fairly uniform particle size. This study also investigated the effect of pH, contact time, and adsorbent dosage on the MB dye adsorption process. The optimum conditions were obtained at pH 11, contact time 75 minutes and adsorbant dosage 0,1 gram with an adsorption efficiency of 89,49%. Therefore, this synthesized silica is promising for the efficient removal of MB dye from aqueous solutions and offers practical applications in wastewater treatment.
Identification of the Redox Reaction Between CuSO₄ and Zn Through Visual Observation in Basic Chemistry Igoy Arya Bimo; Rendra Lebdoyono; Luluk Alifia; Raida Amelia Ifadah
ALCHEMY:Journal of Chemistry Vol 14, No 1 (2026): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v14i1.37816

Abstract

Oxidation–reduction (redox) reactions are important chemical processes characterized by the transfer of electrons between substances and changes in oxidation numbers. This study aims to identify the occurrence of a redox reaction between copper (II) sulfate (CuSO₄) ions and zinc (Zn) metal through observations of changes in solution color, the formation of copper deposits, and physical changes in the zinc metal. The experiment was conducted descriptively using three variations of Zn mass (0.1, 0.2, and 0.3 grams) and was compared with a negative control using ZnSO₄. In the negative control sample, only the physical dissolution of ZnSO₄ occurred without the formation of copper deposits, indicating the absence of a redox reaction. In contrast, in samples using pure Zn metal, the redox reaction proceeded spontaneously, indicated by the fading of the blue color of the CuSO₄ solution and the formation of copper deposits ranging from reddish-brown to dark on the surface of the zinc. Variations in Zn mass affected the rate of Cu²⁺ reduction, where larger metal masses showed a slower initial reaction but still produced copper deposits at the end of the reaction period. This study confirms that Zn acts as the reducing agent and Cu²⁺ serves as the oxidizing agent in the CuSO₄–Zn redox system.
Perbandingan Sensitivitas Rapid Test Kit dan Indikator Alami untuk Deteksi Boraks pada Tahu di Palangka Raya Faisal Faisal; Abudarin Abudarin; Anggi Ristiyana Puspita Sari
ALCHEMY:Journal of Chemistry Vol 14, No 1 (2026): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v14i1.38032

Abstract

Bleng adalah bentuk tidak murni dari boraks. Bleng memiliki kandungan boraks dengan jumlah 12% dalam 1 kg. Bleng digunakan dalam produk makanan, seperti kerupuk, karena berfungsi sebagai pengenyal, perenyah, dan memberi rasa gurih pada produk yang dibuat. Penelitian ini bertujuan membandingkan sensitivitas dan batas deteksi kadar boraks menggunakan metode uji rapid test kit, indikator alami ubi ungu dan kunyit. Metode penelitian ini menggunakan rapid test kit, indikator alami ubi ungu dan kunyit. Indikator alami ubi ungu, kunyit dan rapid test kit digunakan pada sampel tahu yang mengandung boraks. Dari data yang diperoleh, dapat dilihat bahwa batas deteksi boraks dengan metode test kit berada antara 50 mg/gram dan 75 mg/gram. Metode kertas indikator ubi ungu memiliki sensitivitas yang ditunjukkan mulai dari 75 mg/gram. Metode indikator kunyit memiliki batas deteksi yang lebih tinggi dibandingkan dengan metode lain seperti test kit atau indikator ubi ungu. Dengan demikian, urutan batas deteksi kadar boraks dari yang paling peka adalah rapid test kit 75 mg/g, indikator ubi ungu 75 mg/g, dan indikator kunyit 400 mg/g. Rapid Test Kit dan Indikator ubi ungu jauh peka lebih dari indikator kunyit dalam mendeteksi keberadaan boraks pada tahu. Ubi ungu mampu mendeteksi boraks pada kadar 75 mg/g melalui perubahan warna menjadi kehijauan, sementara kunyit hanya bereaksi pada kadar 400 mg/g dengan perubahan warna menjadi merah kecoklatan.