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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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Articles 61 Documents
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Search results for , issue "Vol 2, No 4 (2015)" : 61 Documents clear
Coronary Risk Factors and Collateral Circulation in Acute Myocardial Infarction Sumargo, Sheila; Dewanto, Julius B.; Hidayat, Syarief
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Coronary arterial stenosis, the major cause of acute myocardial infarction (AMI), induces shear stress to surrounding arteriolar endothelium. This stimulates changes in endothelial cells, smooth muscle cells and fibroblast to create collaterals that can provide alternative blood flow to the jeopardized myocardial area. However, coronary collateralization is various among AMI patients. The aim of this study was to analyze the correlation between coronary risk factors and collateral sirculation in AMI patients.Methods: A retrospective cross-sectional study was carried out to 148 medical records of hospitalized AMI patients in Dr. Hasan Sadikin General Hospital Bandung, Indonesia. All patients were assessed for coronary collateral circulation which were graded as good (Rentrop score 2–3) and poor (Rentrop score 0–1). Risk factors noted in this study were age group, sex, hypertension, diabetes mellitus and diagnosis (ST-segment Elevation Myocardial Infarction (STEMI) or Non STEMI (NSTEMI)) according to the medical record data. Results: Hypertension was found to be associated with the presence of good coronary collateral circulation (p=0.02, PR=1.410 [95% CI 1.030-1.930]). Sex, age group, diabetes mellitus and STEMI or NSTEMI diagnosis were not statistically significant.Conclusions: Hypertension was the only coronary risk factor associated to the presence of well-developed coronary collaterals. The increase of myocardial oxygen demand and flow of collateral feeding coronary artery in the setting of hypertension may contribute to the results.  DOI: 10.15850/amj.v2n4.688
Prevalence of Allergic Rhinitis based on World Health Organization (ARIA-WHO) questionnaire among Batch 2010 Students of the Faculty of Medicine Universitas Padjadjaran Fauzi Fauzi; Melati Sudiro; Bony Wiem Lestari
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Allergic rhinitis (AR) is a common disease affecting 5–45% of Asian population. Although it is not a life-threatening disease, AR significantly hampers the quality of life of the sufferers. The prevalence of AR among adults in Indonesia is still unknown. This study aimed to measure the prevalence of AR among batch 2010 students of the Faculty of Medicine, Universitas Padjadjaran.Methods: A cross-sectional study was conducted during June–October 2013 involving Indonesian class batch 2010 students of the Faculty of Medicine, Universitas Padjadjaran. The sampling was performed usingtotal sampling approach. The measurement tool used in this study was the Indonesian translation of the Allergic Rhinitis and its Impact on Asthma-World Health Organization (ARIA-WHO) questionnairee. Thosewho were aware of being diagnosed with AR or had two/more AR defining symptoms in the questionnaire form were considered to have AR. The statistical analysis was conducted by calculating frequencies.Results: A total of 207 questionnaire forms were adequately filled out and returned. Based on the questionnaire, the prevalence rate of AR was 38.2%. Of the 79 AR cases, 66% cases involved females. In addition, 54% of the the AR cases have a parental history of allergic diseases. Nasal obstruction and itchy nose were the most frequent symptoms (90%), followed by rhinorrhea (89%), sneezing (82%), and eye symptoms (62%). Based on the duration, the majority fell into the intermittent group (91%); whereas basedon severity, the majority was in the moderate-severe group (71%).Conclusions: The prevalence rate of AR obtained in this study is within the estimated range of Asian population. [AMJ.2015;2(4):620–5] DOI: 10.15850/amj.v2n4.658
Correlation between Postural Stability and Functional Mobility in Patients with Knee Osteoarthritis Arlinda De Hafsari; Vitriana Vitriana; Alwin Tahid
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Osteoarthritis (OA) is a degenerative joint disorder caused by progressive erosion of articular cartilage. The joint which is commonly affected is theknee joint. Patient with knee OA has increasing pain with decreasing postural stability, and may cause decrease infunctional mobility of the body. The aim of this study was to analyze the correlation between stability and mobility in patients with knee OA.Methods: A cross sectional study was performed to 43 patients from the Rheumatology Clinic of Dr. HasanSadikin General Hospital, Bandung, during  September−October 2013. The ‘Timed Up and Go’ (TUG) test and stabillometric platform examination were performed to analyze the mobility and stability in subjects. The data were analyzed with Spearman’s Correlation.Results: Four subjects (9.30%) had normal functional mobility, 31 subjects (72.09%) had good mobility and need no help of others in their activities, and 8 subjects  (18.60%) had problems and could not stand and walk without help. This study also found 39 subjects (90.69%) had high risk of fall. The p value were 0.005 for correlation between knee OA and lateral static postural stability, 0.138 with anteroposterior static stability, 0.067 with dynamic to position of top right stability, 0.344 with dynamic to position of top left stability, 0.384 with dynamic to position of bottom left stability and 0.357 with dynamic to position of bottom right stability.Conclusions: There is a strong correlation between functional mobility with static postural stability, especially to the lateral position. [AMJ.2015;2(4):550–4] DOI: 10.15850/amj.v2n4.639
Profile of Head and Neck Cancer Patients at Department of Otorhinolaringology-Head and Neck Surgery Dr. Hasan Sadikin General Hospital Bandung Inez Aulia Rakhmawulan; Yussy Afriani Dewi; Nursiah Nasution
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Head and neck cancer is a health problem with a high mortality rate. Head and neck cancer are increasing and effect many individuals from diverse backgrounds. Usually patients come with advanced stages, therefore these conditions could lead to decrease their quality of life. Aim of this study was to describe the profile of head and neck cancer patients at the Otorhinolaringology-Head and Neck Surgery Department, Dr. Hasan Sadikin General Hospital Bandung.Methods: A descriptive cross-sectional method was used from medical records of head neck cancer patients at Department of Otorhinolaringology-Head and Neck Surgery, Dr. Hasan Sadikin General Hospital Bandung from 2008 to 2012 that used the total sampling method.Results: There were 665 patients included in this study, which men who participated were 388 and women were 277. Most of them were elementary educated (44.96%), housewives (32.03%), and those aged 46–55 years old (28.33%). There were nasopharyngeal (38.20%), sinonasal (17.29%), larnyx (13.08%), oropharnyx (6.32%), thyroid gland (6.17%), oral cavity (3.91%), hypopharynx (2.41%), and parotid gland (2.26%) cancer. The major histopathological findings were undifferentiated carcinoma (45.41%) and squamous cell carcinoma (22.26%), those were presented with stage I (7.4%), II (13.5%), III (24.4%), and IV (54.7%).Conclusions: Nasopharyngeal carcinoma was the most predominant cases which majority were presented in advanced stage and major histopathology features was undifferentiated carcinoma, while demografic characteristic mostly were in middle aged and older, men with low education background. [AMJ.2015;2(4):474–9] DOI: 10.15850/amj.v2n4.630
Students’ Perception on Ideal Age of Marriage and Childbearing Mohanambehai Subranmiam; Kuswandewi Mutyara; Hanom Husni Syam
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Early-age marriage is still common in Indonesia, especially in the rural areas. There are many negative effects of the marriage; the young brides may get lower education, lower social status, minimum reproduction control, higher maternal mortality, higher domestic violence rate and others. Thus, this study is conducted to identify the students’ perception on the ideal age of marriage and childbearing.Methods: A cross-sectional descriptive study was conducted from June to September 2013 in Jatinangor using secondary data from Jatinangor Cohort Survey Team. The data comprised two hundred and twenty students from Jatinangor Senior High School and PGRI Vocational School. A hundred and ten males and a hundred and ten females were chosen by random sampling. Questionnaires were given after the written informed consent was obtained from the students.Results: The results showed 74.55% of the students chose 19¬–24 years old as the ideal age of marriage for a woman and 68.64% students chose 25–30 years old as the ideal age of marriage for a man. Moreover, forchildbearing, 25–30 years old was chosen to be the ideal age for both man and woman. The percentage of students agreed to this was 74.55% and 54.09% respectively.Conclusions: Majority of the students agreed on 19–24 years old and 25–30 years old as the ideal age of marriage for woman and man respectively. For childbearing, 25–30 years old was concluded as the ideal agefor both genders. [AMJ.2015;2(4):591–6] DOI: 10.15850/amj.v2n4.661
Clinical Presentation and Laboratory Features in Pediatric Typhoid Fever Patient Susceptibility to First-line Antibiotic Therapy Dewi Ratnasari; Djatnika Setiabudi; Lulu Eva Rakhmilla
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: RTyphoid fever remainsa serious health problem in the world. The main cause of this disease is Salmonella enterica serovar Typhi. These microbes have developed resistance to first-line antibiotics (chloramphenicol, ampicillin, and co-trimoksazol) since 1950. Clinical presentation and laboratory features conducted in children infected with resistant strains tend to be more severe. The objective of this study was to determine the differences of clinical presentation and laboratory features in pediatric typhoid fever patient susceptibility to first-line antibiotics.Methods: This was an analytical cross-sectional study of total 119 typhoid fever children with positive blood culture of Salmonella Typhi based on medical data in Department of Child Health Dr. Hasan Sadikin General Hospital, Bandung during 2008–2012. Inclusion criteria included 76 patients with age range 1–15 years old, given an antibiotic, and had susceptibility test done. Numerical variable was the duration of fever in patients after given an antibiotic. Categorical variable included hepatomegaly, diarrhea, platelet count at admission, and leukocyte count at admission. Data were analyzed using a Mann-Whitney and Chi-square test.Results: There was no statistically significant difference in the duration of fever, leucocyte count at admission, and thrombocyte count at admission between sensitive and resistant response to chloramphenicol, ampicillin, and co-trimoksazol (p>0.05). Leucocyte count at admission in children with sensitive and resistant strain to ampicillin almost showed a difference (p=0.07) but still not statistically significant difference.Conclusions: There is no difference of clinical presentation and laboratory features in pediatric typhoid fever patient susceptible to first-line antibiotics. [AMJ.2015;2(4):584–90] DOI: 10.15850/amj.v2n4.653
Ability and Willingness to Pay Premium in the Framework of National Health Insurance System Aulia Abdillah Ramadhan; Andri Reza Rahmadi; Henni Djuhaeni
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: The National Health Insurance is one of the government’s efforts to improve community access to health services. The government has fixed the premiums to be paid by community, except for underprivileged community. The aim of the study was to identify Ability to Pay (ATP) and Willingness to Pay (WTP) of the national health insurance premium.Methods: A descriptive study which involved 210  housewives who were chosen by rapid survey method was conducted from September to November 2013 in Cipacing village, Jatinangor, Sumedang, West Java. Data collection was using questionnaire to obtain level of ability and willingness to pay the health insurance premium. The results were compared to the required premium by the government (Rp 22,000,-).Results: Most of the respondents were only housewives, but there were still respondents who were private workers. Most of them were 20–39 years old. About 57.6% of the respondents were able to pay for the required premium, but Only 17.4% of the them were willing to pay according to the required premium.Conclusions: The ATP of the respondents are higher compared to the WTP, meaning that most of the respondents are able to pay the requires premium but are not willing to pay it. [AMJ.2015;2(4):502–5] DOI: 10.15850/amj.v2n4.635
Anti-hyperglycemic Effect of Psidium guajava Leaf Infusion Rizda Nurul Zartiana; Samsudin Surialaga; Hikmat Permana
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Prevalence of diabetes mellitus is estimated to increase annually. Numerous people use traditional medicine, such as the Poidium guajava leaf to prevent this disease. This study aimed to analyse the effect of Psidium guajava leaf to inhibit glucose absorption in intestine epithelial membrane of wistar rats.Methods: This laboratory experimental study used 5 wistar rats as subjects in the Laboratory of Biochemistry at Padjadjaran University from 10−26 October 2012. All rats were given three solutions by in situ perfusionmethod. The first was 25 ml 3.0 X 10-3 M glucose solution, the second was 25 ml 3.0 X 10-3 M glucose solution with 1 ml Psidium guajava infusion added, and the third was 25 ml 3.0 X 10-3 M glucose solution.The sample from each solution was taken five times at 0, 15, 30, 45, and 60 minutes after the solutions were given. The spectrophotometer was to quantify the concentration of glucose from the samples. Data were analyzed using Friedman and Wilcoxon test.Results:The means of glucose concentration for each solution from the first solution to the third were 6.126 mg/dl, 2.447 mg/dl, and 5.345 mg/dl. The probability value showed significant difference between the first and second solutions (p ≤ 0.05).Conclusions: Psidium guajava leaf infusion can inhibit glucose absorption in wistar rat intestine and the effect is reversible. [AMJ.2015;2(4):546–9] DOI: 10.15850/amj.v2n4.508
Knowledge and Risk Factors for Osteoporosis among Pre-elderly Muhammad Ramdhani; Dicky Mulyadi; Nita Arisanti
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Osteoporosis is a disease characterized by abnormal loss of bone density resulting in bones that are brittle and liable to fracture. Most cases of fracture in the world are due to osteoporosis. In Indonesia, the prevalence of osteopenia (early osteoporosis) and of osteoporosis are relatively high. One of the causes of this situation is the low level of public knowledge about how to prevent osteoporosis. This study was conducted to identify the knowledge and risk of osteoporosis among pre-elderly at CipacingVillage Jatinangor District in 2014.Methods: This descriptive study was conducted at Cipacing Village Jatinangor District to 160 respondents who were classified as pre-elderly (aged 45-59 years) and assessed on knowledge and risk factors forosteoporosis through questionnaire-guided interviews after the informed consent was obtained. The collected data were presented using frequency distribution.Results: A total of 100 respondents (62.5%) had good knowledge about osteoporosis-related information, including definitions, causes, risk factors, signs and symptoms, impacts, and prevention. Most respondents,79 respondents (49.4%), are at risk for osteoporosis.Conclusions: Knowledge of osteoporosis among pre-elderly at Cipacing Village Jatinangor District are largely classified into “good knowledge” category. [AMJ.2015;2(4):608–14] DOI: 10.15850/amj.v2n4.659
Relationship between Body Mass Index with Menstrual Cycle in Senior High School Students Rinasyah Ganesh; Lola Ilona; Ryadi Fadil
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: In recent years, there is an escalation of menstrual disorders in both developing and developed countries. One of the important factors that contribute to menstrual disorders is body fat content. In developing countries like Indonesia, young women in certain cultures get married at average age of 16 years. At the same time, the number of malnourishment among adolescent is increasing. This study was conducted to analyze the relationship between body mass index (BMI) and menstrual cycle in senior high school students.Methods: This study included 330 girls ages 15−17. This study was conducted in Jatinangor, Sumedang from the period of August–October 2013 using a cross-sectional study. Questionnaires assessing their menstruation and their weight and height were collected after obtaining the respondents consent.The collected data were analyzed using the independent T-test.Results: Most of the respondents had normal BMI, menstrual interval, amount and duration. There was no relationship between BMI and menstrual interval and menstrual amount (0.74 and 0.878 respectively), however there was relationship between BMI and menstrual period (p= 0.036).Conclusions: Menstrual abnormalities among female adolescents are common. Based on this study, BMI seems to be moderately associated with menstrual cycle, especially with menstrual period, although a possibility still remains that body fat affects the menstruation superiorly. [AMJ.2015;2(4):555–60] DOI: 10.15850/amj.v2n4.640

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