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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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Search results for , issue "Vol 4, No 3 (2017)" : 60 Documents clear
Early Detection of Suspected Systemic Lupus Erythematosus in Community-Dwellings in West Java Indonesia Nadia Gita Ghassani; Laniyati Hamijoyo; Soeseno Hadi
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (576.738 KB)

Abstract

Background: Prevalence of systemic lupus erythematosus (SLE) has been known in almost all countries around the world.  Contrary to this, in Indonesia, neither a national epidemiologic study on SLE nor any direct study on SLE in the general population has been conducted. Early detection of SLE is needed as a first step to determine prevalence of SLE in Indonesia as well as to prevent further complications. This study aimed to obtain the prevalence of suspected SLE in community-dwellings.Methods: This study was conducted in the period September to November 2015 and used the descriptive cross-sectional method. The respondents were people who were at least 18 years old and lived in selected blocks in three different villages in Jatinangor, West Java. Data were obtained from secondary sources of a previous SLE screening study that was incorporated in a study on “Epidemiology of hypertension and albuminuria in Jatinangor” in 2014, using the multistage sampling method. Suspected SLE was based on the Liang screening questionnaire. The collected data were presented in tables.Results: There were 72 respondents (8%) suspected to have SLE. Most of the cases were female (Odds ratio:1.47) and 51–60 years old.  The most clinical manifestation was painful swollen joints >3 months.Conclusions: The existence of suspected SLE cases in Jatinangor’s population, as an example of Indonesian population should be a concern so that examinations could be carried out to make sure that  respondents with SLE can be provided  prompt interventions  to prevent further complications. 
Burden of Pediatric Cancer Treatment: Results of Online Pediatric Cancer Registry Prototype 1 at A Third Referral Hospital in Indonesia Nur Melani Sari; Lelani Reniarti; Nur Suryawan; Susi Susanah; Kurnia Wahyudi
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (606.214 KB) | DOI: 10.15850/amj.v4n3.1204

Abstract

Background: Despite the impressive progress of high-income countries, childhood cancer survival remains low in low and middle-income countries. Cancer is yet to be considered as a significant public health issue which has implicate only few pediatric cancer registry has been well established. The study aimed to describe the burden of pediatric cancer treatment in a third referral hospital in Indonesia through pediatric cancer registry.Methods: A-three-year retrospective analysis of 15 pediatric cancer diagnosed in children aged under 14 years was conducted at Dr Hasan Sadikin General Hospital, Bandung.  Data were extracted from Online Bandung Pediatric Cancer Registry Prototype 1 and analyzed for age, gender, type of cancer. The outcomes were classified as treatment abandonment, treatment refusal, interrupted treatment, death during treatment, and completed treatment.Results: Seven-hundred and seventy-three children, 452 males and 321 females, were diagnosed with 15 types of malignancies.  Peak incidence for each malignancy was different: at a young age was found in retinoblastoma and hepatoblastoma (mean; 3yo) while at adolescence in bone tumor and chronic myelocytic leukemia (9.1; 10 yo respectively). Distribution of the foremost malignancies recorded was: acute lymphoblastic leukemia (44.5%), retinoblastoma (15.2%), and non-Hodgkin lymphoma (8.9%). The cancer cure rate was very low (9.5%), treatment abandonment was still high (41.7%) and most patients died (27.8%) in the course of therapy either from advanced disease, infection, or late presentation. Meanwhile, 167 patients still continued the interrupted treatment.Conclusions: Cancer management is the burden for hospital, however the general outcome is very poor. 
Quality of Life in Children with Atopic Dermatitis Muhammad Akbar Wicaksana; Oki Suwarsa; Fenny Dwiyatnaningrum
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2911.887 KB) | DOI: 10.15850/amj.v4n3.652

Abstract

Background: Atopic dermatitis (AD) is the most common chronic skin disease in children which caused significant morbidity and impaired quality of life (QoL). The main goal of AD therapy is to prevent flare -ups, prolong remission and increase QoL. Therefore, the study aimed to discover QoL in children with AD.Methods: The study was conducted at Pasundan Public Health Centre, Al Islam General Hospital and Kimia Farma Private Dermatology Clinic, from September to November 2015. This descriptive study used consecutive sampling with 24 outpatients who were admitted to the health facility and diagnosed as AD. A questionnaire on Infant Dermatitis Quality of Life for infants aged 0–4 years, and Children Dermatology Life Quality Index for children aged 5–16 years was used in this study to measure QoL.Results: Out of 24 patients, 9 patients aged 0–4 years had mean score of 4.44±4.36, and 15 patients aged 5–16 years had mean score of 5.80±3.95. Mean SCORAD Objective in patients aged 0–4 and 5–16 was 15.61±7.75 and 17.44±11.Conclusions: The QoL in children with AD vary among patients. Most of the patients have mild-moderate impairment in QoL. 
Three-Year Study of Geriatric Skeletal Muscle Strength at a Top Referral General Hospital, West Java, Indonesi Sigop Elliot Parsaulian Lumbantoruan; Vitriana Vitriana; Lazuardhi Dwipa
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.46 KB) | DOI: 10.15850/amj.v4n3.1195

Abstract

Background: One of the aging effects is the decrease of skeletal muscle strength. The objectives of this study was to analyze the geriatric skeletal muscle strength by hand grip strength according to the characteristics of the elderly.Methods: An analytic retrospective study was carried out to 99 medical records of elderly who sought medication at the Geriatric policlinic of Dr. Hasan Sadikin General Hospital as the top referral hospital in West Java, Indonesia from 2012–2014. The result of hand grip strength measurement were grouped based on the characteristics of gender, age, body mass index (BMI), Barthel Index score, Mini Nutritional Assessment (MNA) score, number of disease and number of medication. All data were taken from patient’s medical records. The collected data were statistically analyzed with unpaired T-test and one way ANOVA test.Results: Among the 99 subjects, most of the subjects were male, under 80 years old,   independent living persons, had normal BMI, and normal nutritional level according to Mini Nutritional Assessment. Most of the subjects had more than 3 diseases per person and less than 5 sorts of medication. Male had higher hand grip strength compared to female and it was statistically significant (p=0.04). Based on ADL score, Independent living had higher hand grip strength compared to other level (p=0.008).Conclusions: From all the variables measured, only gender and  Activity Daily Living level contibute to the hand grip strength. 
Pulmonary Function of Tuberculosis Patients in Medication at Dr. Hasan Sadikin General Hospital Bandung 2013–2014 Shalahuddin Galih Pradipta; Hendarsyah Suryadinata; Setiawan Setiawan
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Tuberculosis (TB) is a dangerous global disease that already affects millions of people in the world and acts as the second most frequent cause of death in infectious diseases. Tuberculosis mostly attacks the lung and the inflammation process causes lung damage. The lung damage causes a decrease in pulmonary function. There has been no study about tuberculosis patient lung function in the advanced stage of medication.Methods: This study was conducted from August–October 2014 at DOTS Policlinic of Dr. Hasan Sadikin General Hospital Bandung. The study population was lung TB patients. The inclusion criteria were 1st category lung TB patients with anti-TB drug treatment on intensive phase. The exclusion criteria were extrapulmonary TB patients, patients with lung surgery history, and patients with asthma or chronic obstructive pulmonary disease (COPD). This study used purposive sampling. The subjects were given a spirometry test where the forced expiratory volume 1 second (FEV1), forced vital capacity (FVC), and their ratio were collected and then interpreted.Results: Among the 60 subjects included in this study, the data showed that 83.4% of the subjects had a decreased pulmonary function consisting of obstructive (6.7%) and restrictive patterns (76.7%).Conclusions: The majority of pulmonary TB patients treated with 1st category anti-TB drugs during intensive phase have a decrease in pulmonary function and most of them have restrictive pattern of pulmonary function.
Correlation between Short-Term Memory and Achievement of Athletes Ryandika Elvereza Mustari; Leonardo Lubis; Nani Kurniani
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Human activity is largely related to thought processing or cognition. One of the most important components of cognition is memory. Individuals who undergo heavy activities, such as athletes, use a lot of memory in the subject’s activities, especially during competitions. The purpose of this study was to find out whether there was a correlation between the capability of short term memory with the performance of an athlete during a competition, especially those measured by achievements.Methods: This study was an analytic observational correlation study with a cross-sectional design and involved 201 athletes as respondents from 12 branches of sports. The study was conducted in the Indonesian National Sports Committee (KONI) building from September to November 2015. Digit Span Forward and Backward were used to collect short term memory data and was performed after a consent form and the respondent’s identity was recorded. The athlete’s achievements data was gathered by an interview and recapitulation of athlete’s achievements in the last five years.Results: OA total of 186 data was analyzed and found a negative and  insignificant correlation between achievement and short-term memory based on digit span tests both forward (r=0.095 p=0.196) and backward(r=0.039 p=0.196). Conclusions: There is no correlation between short term memory and the achievements of an athlete.   
Destructive Effect of Calcium Hypochlorite against Pseudomonas aeruginosa Biofilm Ilma Arifani; Gita Widya Pradini; Insi Farisa Desy Arya; Adi Imam Cahyadi
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (681.179 KB) | DOI: 10.15850/amj.v4n3.1205

Abstract

Background: Pseudomonas aeruginosa is the most common bacteria contaminating the hemodialysis water and has high capability to form a biofilm. The presence of biofilm is hazardous because it becomes a constant source of bacterial and toxin release toward the hemodialysis patient’s blood. Calcium hypochlorite (Ca(OCl)2) is an easily obtained disinfectant. This study was aimed to detect the destructive effect of Ca(OCl)2 against P. aeruginosa biofilm and the optimal disinfectant concentration required to achieve significant effect.Methods: This experimental study was conducted in six replicates from September to October 2015 in Microbiology Laboratory of Faculty of Medicine Universitas Padjadjaran Bandung. A modified tissue culture plate method was performed to grow P. aeruginosa biofilms which were subsequently treated with Ca(OCl)2 in various chlorine concentrations, namely 20, 30, 40, and 500 parts per million (ppm). The data was analyzed using Welch Analysis of Variance (ANOVA) and Games-Howell post-hoc tests and presented in tables.Results: Data were obtained from 36 flat-bottomed polystyrene wells. There was a statistically significant mean difference between groups [F(4, 11.92)= 91.198, p<0.001)]. All of the tested chlorine concentrations caused significant decreases in biofilm optical densities (p = 0.027 for 20 ppm and p< 0.001 for 30, 40, and 500 ppm).Conclusions: Ca(OCl)2 with chlorine concentrations of 20, 30, 40, and 500 ppm have significant destructive effect against P. aeruginosa biofilm. The mean differences among treated groups were not significant. The most optimum concentration is 30 ppm.
Nasal Endoscopy Findings in Acute and Chronic Rhinosinusitis Patients Stephanie Dharmaputri; Lina Lasminingrum; Yulia Sofiatin
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: According to European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) 2012, rhinosinusitis is diagnosed based on symptoms, nasal endoscopy, and CT scan. The CT scan is the gold standard to diagnose rhinosinusitis, but its high cost and lack of availability become the problems in Indonesia. Hence, nasal endoscopy is a choice to diagnose rhinosinusitis. This study was aimed to describe the findings of nasal endoscopyin in acute and chronic rhinosinusitis. Methods: This cross-sectional descriptive study was performed using medical record of acute and chronic rhinosinusitis patients. The samples were chosen with consecutive sampling. Inclusion criteria of this study were patients that underwent nasal endoscopy examination in Otorhinolaryngology–Head and Neck Surgery Clinic Dr. Hasan Sadikin General Hospital Bandung in 2014.The collected data were analyzed in the form of tables.Results: Among 138 patients, the number of female patients (55.1%) was higher than male patients. Majority of the patients (37.5%) were 25–44 years old. Majority of the chief complaint was nasal obstruction (48.6%). The patients with allergic history (48.6%) were higher than patients without allergic history (19.6%). According to nasal endoscopy results, nasal discharge and edema were found in most of the patients (68.8% and 63.0%), but nasal polyp was only found in 15.9% patients. Other findings, such as hypertrophy concha or nasal septum deviation, were also found on 87.7% patients. Conclusions: Most of the rhinosinusitis patients are found with at least one of the following results of nasal endoscopy, which are nasal discharge, edema, or nasal polyp. 
Health Related Quality of Life and Residual Symptoms in Prostatic Surgical Treatment at Bethesda Hospital Yogyakarta: a Retrospective Study Daniel Mahendra Krisna; Hariatmoko Hariatmoko; Rizaldy Taslim Pinzon
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.415 KB) | DOI: 10.15850/amj.v4n3.968

Abstract

Background: The incidence of Prostate Enlargement (PE) has been increasing over the years. The satisfaction towards the treatment result and life quality (QOL) improvement must be the key point of PE treatment. QOL is affected by many conditions, such as age, socioeconomic status, comorbid disease, and type of surgery. The objective of the study was to assess the QOL in PE patients post surgery, to explore the predictor factor, and to assess the satisfaction related to urinary functionality in the Indonesian context. Methods: A retrospective study was conducted and the subjects were all PE patients who underwent surgical treatment. EQ-5D-5L/EQ-VAS and Index Quality of Life (IQL) were used to assess the patient’s QOL & treatment satisfaction. The subjects were divided into several sub-groups based on age, type of surgery, comorbid condition, type of ward, funding source, histopathological result, and the year of treatment. The collected data wee analyzed using Mann-Whitney test, Kruskal Wallis test, or Chi-square test, Spearman’s rho test and multiple linear regression. Results: All the 149 subjects were at the average age of 69.09 years . There were no significant statistical differences in QOL between age, comorbid conditions, and histopathology result. Health insurance (HI) was significantly associated with QOL. There were improvements of IQL subjects. The most symptoms remaining was frequency (47.4%).Conclusions: Life improvement must be the major purpose of PE therapy. The association between HI with QOL suggests that a better HI in developing countries can ensure a better quality of life outcome.
Identification of Pathogen Protozoans (Cryptosporidium spp and Giardia lamblia) from Canteen’s Water-sources at Jatinangor, West Java, Indonesia Komathi Nair Murugesan; Ridad Agoes; Sri Yusnita Irda Sari
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: The prevalence of intestinal protozoan infection caused by Cryptosporidium spp and Giardia lamblia has been rapidly increasing in developing countries. Contamination of water-sources by intestinal protozoans can spread infection to humans when it is consumed without any specific treatment. Jatinangor is an educational area where many universities are located and many students live in this area. This study aimed to identify the presence of intestinal protozoa (Cryptosporidium spp and Giardia lamblia) in water-sources used by canteens at Jatinangor area to detect the magnitude of protozoans intestinal infections.Methods: A descriptive cross sectional study was carried out from August to September 2014. Raw water samples from reservoir tanks, water containers and tapwater were taken from all canteens located along the main road of Jatinangor. Samples were centrifuged and divided into two portions; two drops from the first test tube was stained with Lugol solution and observed by 2 observers under a light microscope for Giardia lamblia, and sediments from the second test tube was stained using acid fast staining then observed for Cryptosporidium spp under the light microscope. Results: Out of 50 samples, 26 were positive for parasites, of which 22 (44%) were contaminated by Cryptosporidium spp and 4 (8%) were contaminated by Giardia lamblia.Conclusions: Half of the raw water-sources in Jatinangor are contaminated by Cryptosporidium spp and Giardia lamblia. Proper water treatment should be implemented by the owners of the canteens before it is consumed as drinking water. 

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