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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Arjuna Subject : -
Articles 1,068 Documents
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Anonna muricata Linn Leaf Effect in Inhibiting SGPT Elevation Galih Tanaya; Kuswinarti Kuswinarti; R. Nina Susana Dewi
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

  Background: Hepatitis is an infection or inflammation disease of the liver which is caused by virus, toxic substance, and immunological abnormalities. Soursop plant as a medicinal plants is known to have an antioxidant effect and nowadays is used as an alternative drug for hepatitis. One of the methods to assess liver function is to measure the serum Glutamate Piruvate Transaminase (SGPT) level. The purpose of this study was to find the effect of Soursop Leaf  in inhibiting the SGPT elevation .Methods: An experimental study was conducted on 25 white male rats of wistar strain in the pharmacology laboratory of Faculty of Medicine, Universitas Padjadjaran during the period of September to October 2012. The rats were divided into 5 groups (group 1 and 2 as control; group 3, 4, and 5 as treatment groups treated by 200, 400, 600 mg/kgbw soursop extract, respectively). The soursop extract was administered to the treatment groups for 8 days. On the 8th day, group 2, 3, 4, and 5 received 1.6 ml CCl410% intraperitoneally. After 18 hours, the mean SGPT levels from all groups were measured. ANOVA test was used to analyze the result.Results : The mean SGPT levels were lower in the 3rd, 4th, and 5th group compared to group 2. There was a significant difference among treatment groups. Group 3 had the most significant result.Conclusion: Soursop leaf inhibits the elevation of SGPT level. Keywords: Hepatitis, SGPT, soursop leaf (Annona muricata) DOI: 10.15850/amj.v2n1.438 
Upper Lower Segment Ratio Comparison between Obese and Normal Children Aged 7 to 10 Years Old Muhammad Zulfikar Azhar; R.M. Ryadi Fadil; Edhyana K. Sahiratmadja
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Upper lower segment ratio is an anthropometric measurement that often used to detect the presence of abnormal growth. Growth is affected by many factor, one of them is nutrional status. Obesity prevalence in Indonesian children increases annually. These children show an accelerated growth in pre-puberty compared to normal children in their age. This study aimed to analyze the difference in upper lower segment ratio between obese and normal children aged 7 to 10 years old.Methods: A cross sectional study was carried out in children aged 7 to 10 years old in three Elemantary School in Bandung during September–October 2013. Height and weight were measured to calculate body mass index (BMI) score and were grouped into obese (BMI >95th percentile) and normal (BMI 10th–85th percentile). The upper lower segment ratio was compared between obese and normal children and the level of the significant difference were analyzed by unpaired T-test.Results: From a total of 200 children recruited, 90 were obese and 110 were normal. There was no significant difference between upper lower segment ratio in obese and normal children (p=0.603) with mean ratio 1.137 and 1.142 respectively. The mean of upper lower segment ratio in obese boys was higher than normal boys (mean ratio 1.15 and 1.14 respectively), but obese girls had a lower ratio compared to normal girls (mean ratio 1.12 and 1.14 respectively).Conclusions: There is no difference between upper lower segment ratio in obese and normal children aged 7 to 10 years old. [AMJ.2016;3(1):147–51] DOI: 10.15850/amj.v3n1.721
Clinical Profile and Outcome of Myocarditis in Children at Dr. Hasan Sadikin General Hospital Bandung from 2008 to 2012 Erza Nurtriandari; Rahmat Budi; R. B. Soeherman
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Diagnosis of myocarditis in children is still challenging due to its inconsistent and wide spectrum of clinical manifestations. There is no specific laboratory test available. This may obscure the true incidence of myocarditis. The purpose of this study was to describe clinical profile and outcome of myocarditis in children.Methods: A descriptive study was performed using 80 medical records of hospitalized pediatrics patients with myocarditis in Dr. Hasan Sadikin General Hospital Bandung from January 2008 to December 2012. The obtained data were age, gender, nutritional status, etiology, chief complaint, physical examination, laboratory findings, other examinations and outcome of the disease. The collected data were analyzed and presented in the form of frequency distribution.Results: The mean age of the patients was 91.46 (45.93) months old, predominantly male. The most etiology was dengue infections (61%). High fever was found as the most common chief complaint (38%) and the most common found in physical examinations were tachypnea (65%) and hepatomegaly (55%). Electrocardiography (ECG) showed the first degree atrioventricular block (AV block) (35%), aspartate aminotransferase (AST) and creatine kinase myocardial band (CKMB) was increased in more than 80% of patients. The majority of patient was improved. Shock was the common complication.Conclusions: Dengue is the most etiology of myocarditis etiology. Tachypnea, hepatomegaly, the first degree AV block in ECG, elevated AST and CKMB were the most common presentations. Most of the patients were improved during treatment. [AMJ.2017;4(1):118–24DOI: 10.15850/amj.v4n1.1031 
Etiology of Symptomatic Focal Epilepsy based on Neuroimaging Result in Neurology Outpatient Clinic of Dr. Hasan Sadikin General Hospital Agastya Prabhaswara; Suryani Gunadharma; Uni Gamayani
Althea Medical Journal Vol 6, No 1 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (68.842 KB) | DOI: 10.15850/amj.v6n1.1556

Abstract

Background: Focal epilepsy is the most common type of epilepsy that can be caused by structural lesions. Images from neuroimaging can show those structural lesions that may point to the etiology of epilepsy and would affect the management of epilepsy. The aim of the study was to explore the possible etiology of symptomatic focal epilepsy from neuroimaging result at the Neurology Outpatient Clinic in Dr. Hasan Sadikin General Hospital.Methods: This study was a cross-sectional descriptive study. The medical records that fulfilled the inclusion criteria were collected at the Neurology Outpatient Clinic of Dr. Hasan Sadikin General Hospital from the year 2017. The inclusion criteria were symptomatic focal epilepsy patients that had abnormal neuroimaging result.Results: In total, there were 71 medical records collected of which eight etiologies of symptomatic focal epilepsy were found, that were vascular disorder caused by strokes (33%), tumors (21%), hippocampal sclerosis (20%), infections (11%), head trauma (6%), malformations of cortical development (4%), vascular malformations (3%), and phakomatosis (1%). Vascular disorder was the most abundant etiology found in all brain lobes, except in temporal and frontal lobes, which also most often caused by hippocampal sclerosis and tumors, respectively.Conclusions: Vascular disorders due to stroke, is the most abundant etiology found in symptomatic focal epilepsy, therefore, stroke patients need to be informed about the possibility of having epilepsy later on.
Nurses’ Knowledge of Blood Culture Sampling Procedure Wulan Ardhana Iswari; Chrysanti Murad; Ida Parwati
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: False-positive blood culture results due to contaminated samples have shown to increasepatients’ health costs, including the use of broad spectrum antibiotics and prolonged hospital length ofstay. While previous research have suggested that increasing staff knowledge on proper specimen collectionlowers contamination rates significantly, staff’s current knowledge of hospital-recommended samplecollection procedure have yet to be assessed in Dr. Dr. Hasan Sadikin General Hospital, Bandung, Indonesia.Methods: This was a cross-sectional descriptive study on 81 Emergency Department nurses in Dr. HasanSadikin General Hospital, Indonesia. Subjects were asked to complete a questionnaire in order to measuretheir knowledge of blood culture sampling procedure in accordance with the hospital’s standard operatingprocedure.Results: Among 81 subjects enrolled, 51 managed to adequately describe the prerequisites in proper bloodculture sampling procedure and their purpose as dictated by Dr. Hasan Sadikin General Hospital’s standardoperating procedure.Conclusions: Up to 67% of nurses conducting blood sampling procedure in Dr. Hasan Sadikin GeneralHospital’s Emergency Department understood the prerequisites of hospital-recommended blood culturesampling procedure and their purpose.
Epidemiology of Giant Cell Tumor in Dr. Hasan Sadikin General Hospital Bandung from 2010-2013 Kirtana Gunasegaran; M.Naseh Sajadi Budi Irawan; Anglita Yantisetiasti
Althea Medical Journal Vol 3, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Giant cell tumor (GCT) of bone is a primary bone tumor. It is commonly seen in South East Asia and found in female around 20–45 years old. The GCT mostly occurs in epiphysis around the knee. The patients normally suffer from pain, swelling, limitation of joint movement, and pathologic fracture. This study aimed to determine the epidemiology of GCT of the bone based on age, sex, location, type, metastases, and recurrence in Dr. Hasan Sadikin General Hospital Bandung.Methods: A descriptive study with retrospective cohort using total sampling method was used to obtain 33 medical records of patients with GCT of bone in Department of Orthopedic & Traumatology and Anatomical Pathology Dr. Hasan Sadikin General Hospital Bandung in the period of January 2010–December 2013.Results: The GCT of bone was mostly found in female of 20 to 29 years old and around 32 years old in male. Distal femur will be the most common site while zygoma, mandibular vertebrae, proximal tibia were rare sites. Twenty nine cases were benign lesion and the rest (4 cases) were malignant. The probability of GCT of bone to metastasize to lungs was very low. Four recurrences occurred within a year.Conclusions: The GCT of bone in male mostly occurs in the third and fourth decade of age. It is found around the knee, mostly benign, rarely metastasize to the lungs and recurrence happens within a year. [AMJ.2016;3(2):244–7] DOI: 10.15850/amj.v3n2.477
Level of Activity Daily Living in Post Stroke Patients Greesea Dinamaria Whitiana; Vitriana Vitriana; Aih Cahyani
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.066 KB) | DOI: 10.15850/amj.v4n2.1068

Abstract

Background: Stroke is the leading cause of disability and dependency which directly decrease patient’slife quality . Disability caused by stroke can be prevented by holistic and comprehensive management plan of stroke. Until now, there was no study conducted to evaluate management for post stroke patients in Dr. Hasan Sadikin General Hospital (RSHS). Therefore, this studyaimed to describe level of activities of daily living (ADL) in post stroke patients in Neurology unit of RSHS as a basic evaluation for a better management hereafter.Methods: This descriptive quantitative study participated by 31 post-stroke outpatients in Neurology Policlinic of RSHS was conducted from September to October 2015. Interviews were done to assess level of ADL by the Barthel Index score. Variables  correlated with ADL (age, gender, stroke type, stroke occurrence, stroke risk factors and muscle strength) were collected from medical records. Collected data was input and presented in tables. Results: There were 19 females and 12 males with the age group of 55-64 year old (35.5%). Most subjects had first stroke attack (71.0%). The most common type and risk factor were ischemic stroke (83.9%) and hypertension (81%) respectively. Patients with a maximum score in the entire extremity muscle strength were in the range of 60-70%. Out of the 31 patients, 18 (58.1%) were classified as independent in ADL. Conclusions: The majority of post stroke patients in the Neurology unit of RSHS wereindependent in ADL.  DOI: 10.15850/amj.v4n2.1068
Physical Fitness Component Profiles of Futsal Team Members of Universitas Padjadjaran in November 2011 Raden Muhammad Tanri; Juliati Juliati; Vitriana Vitriana
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background:  To be a good athlete, an athlete needs to possess good predominant components of physical fitness. Futsal Team of Universitas Padjadjaran has never won any competition. This study was conducted to identify the predominant component profiles of physical fitness of Futsal Team members of Universitas Padjadjaran. The predominant component profiles were classified based on the Indonesian National Sport Committee (KONI) standard.Methods: This study was carried out at the Faculty of Medicine Student Center of Universitas Padjadjaran in November 2012. Twenty two members of the Futsal Team were enrolled as subjects of the study. The study used the step test to examine aerobic endurance; the leg dynamometer to measure leg muscle strength; the squat jump test to test the leg muscle endurance; the vertical jump test to measure leg muscle power; and the sit and reach test to measure lower extremity flexibility. The data collected were analyzed using percentage.Results: Leg muscle strength was mostly in the fair category (95%). Leg muscle power was mostly in the good category (41%). Leg muscle endurance was mostly in the good category (82%). Leg flexibility was mostly in the excellent category (91%) and aerobic endurance was mostly in the good category (41%).Conclusions: Only several members of Universitas Padjadjaran Futsal Team have an excellent physical fitness profile. Most of the members fell into the fair and good category. DOI: 10.15850/amj.v2n3.524
Effect of Cucumis sativus L on Glucose Absorption through Intestinal Mucosal Membrane of Wistar Rat Models Fitri Amalia; Samsudin Surialaga; Sylvia Rachmayati
Althea Medical Journal Vol 1, No 1 (2014)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: The Cucumis sativus L has been used in traditional medicine for several conditions, with one of them being diabetes mellitus. The purpose of this experiment is to observe the anti-hyperglycemic effect of Cucumis sativus L on glucose absorption through the intestinal mucosal membrane of Wistar rats.Methods: The research was conducted on September–November 2012 at Biochemistry Laboratory, Faculty of Medicine, Universitas Padjadjaran. Using in situ perfusion method, the rat’s epithelial mucosa in the intestine was bathed in a simple glucose solution in control, and bathed in glucose and Cucumis sativus L infusion in treatment. After admission, a sample was taken from the digestive tract and the glucose level was measured through a spectrophotometer.Result: There is no significant difference in the absorption of control and treatment solution.Conclusion: The Cucumis sativus L does not have any significant effect on the glucose absorption through the intestinal mucosal membrane. Further studies are still needed to reveal the antihyperglycemic mechanism of Cucumis sativus L.[AMJ.2014;1(1):30–4]Keywords: Antihyperglycemic effect, Cucumis sativus L (Cucumber), Diabetes mellitus, Glucose absorption Pengaruh Cucumis sativus L pada Penyerapan Glukosa melalui usus mukosa Membran Tikus WistarLatar Belakang: Buah timun (Cucumis sativus Linn.) telah dipercaya sebagai obat tradisional beberapa penyakit, salah satunya adalah diabetes melitus. Penelitian ini ditujukan untuk mengetahui efek antihiperglikemi buah timun terhadap transpor glukosa melalui sel epitel mukosa usus halus tikus wistar.Metode: Dengan menggunakan metode perfusi in situ, usus halus tikus dialiri larutan glukosa selama 60 menit untuk kontrol dan larutan glukosa yang telah diberi infusa timun selama 60 menit untuk perlakuan. Sampel yang diambil berupa cairan yang dialirkan ke usus pengambilan dilakukan pada menit ke 0, 15, 30, 45, 60, kemudian dilakukan pengukuran kadar glukosa dengan menggunakan spektofotometri. Penelitian ini dilakukan pada September–November 2012 di Laboratorium Biokimia, Fakultas Kedokteran, Universitas PadjadjaranHasil: Tidak terdapat perbedaan bermakna antara penyerapan glukosa pada larutan kontrol dengan larutan perlakuan.Simpulan: Cucumis sativus L tidak memiliki pengaruh yang signifikan terhadap penyerapan glukosa melalui membran mukosa usus. Penelitian lebih lanjut masih diperlukan untuk mengetahui mekanisme anti hyperglycemic Cucumis sativus L.Kata kunci: Cucumis sativus L (Cucumber), diabetes mellitus, efek antihyperglycemic, penyerapan glukosa DOI: 10.15850/amj.v1n1.294
Malnutrition-Inflammation Score (MIS) and Physical Activity among Hemodialysis Patients in Dr. Hasan Sadikin General Hospital Bandung Rizka Putri Hamuktiono; Rudi Supriyadi; Nida Suraya
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Protein Energy Malnutrition (PEM) related to inflammation and physical activities reduction occur commonly among hemodialysis patients. This study aimed to describe Malnutrition-Inflammation Score (MIS) and physical activity of hemodialysis patients.Methods: This study involved 117 patients in the Hemodialysis Unit of Dr. Hasan Sadikin General Hospital Bandung from September to October 2014. Secondary data were collected to examine MIS and physical activity, which was measured by using Baecke Physical Activity Questionnaire. The collected data were presented using frequency distribution.Results: Eighty (68.4%) patients had MIS <6, thirty seven (31.6%) patients had MIS ≥6, and ninety four (80.3%) patients had light physical activity.Conclusions: Most of the patients have MIS <6 and are physically inactive. [AMJ.2015;2(4):601–7] DOI: 10.15850/amj.v2n4.478

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