Althea Medical Journal
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Articles
1,068 Documents
Correlation between Oxygen Saturation and Hemoglobin and Hematokrit Levels in Tetralogy of Fallot Patients
Farhatul Inayah Adiputri;
Armijn Firman;
Arifin Soenggono
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran
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Background: Hemoglobin and hematocrit levels increase in Tetralogy of Fallot (TOF) but the oxygen saturation declines. Reduced hemoglobin in circulating blood as a parameter of cyanosis does not indicate rising hemoglobin due to the ‘not-working’ hemoglobins that affect the oxygen saturation. Increasing hematocrit is the result of secondary erythrocytosis caused by declining oxygen level in blood, which is related to the oxygen saturation. This study was conducted to find the correlation between oxygen saturation and hemoglobin and hematocrite levels in TOF patients.Methods: This study was undertaken at Dr. Hasan Sadikin General Hospital in the period of January 2011 to December 2012 using the cross-sectional analytic method with total sampling technique. Inclusion criteria were medical records of TOF patients diagnosed based on echocardiography that included data on oxygen saturation, hemoglobin, and hematocrite. Exclusion criteria was the history of red blood transfusion. Results: Thirty medical records of TOF patiens from Dr. Hasan Sadikin General Hospital Bandung were included in this study. Due to skewed data distribution, Spearman correlation test was used to analyze the data. There was a significant negative correlation between oxygen saturation and hematocrit level (r= -0.412; p=0.024) and insignificant correlation between oxygen saturation and hemoglobin (r=-0.329; p= 0.076).Conclusions: There is a weak negative correlation between oxygen saturation and hematocrite levels. [AMJ.2016;3(1):152–5]DOI: 10.15850/amj.v3n1.724
Incidence of Postoperative Nausea and Vomiting in Dr. Hasan Sadikin General Hospital Bandung Period May to October 2013
Aisyah Ummu Fahma;
Iwan Fuadi;
Jimmy Setiadinata
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran
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Background: Postoperative nausea and vomiting (PONV) is common complication in patients undergoing surgery with anesthesia. The incidence of PONV is ranging between 20% and 30%. Despite many other studies about PONV in other regions, the descriptive data about PONV in Dr. Hasan Sadikin General Hospital Bandung is still unknown. The aim of this study was to determine the incidence of PONV in Dr. Hasan Sadikin General Hospital Bandung.Methods: This descriptive study used a cross-sectional method. As many as 521 medical records in Departement of Anesthesiology and Intensive Care Dr. Hasan Sadikin General Hospital Bandung from May 5th to October 31st 2013 were reviewed. The subjects were taken by using total sampling technique. Data collected were gender, age, type of surgery, type of anesthesia, duration of surgery, administration of nitrous oxide, and administration of neostigmine.Results: Of 521 patients,the incidence of PONV was 20.5%. Female had higher incidence of PONV than male. Postoperative nausea and vomiting was the most frequent in the age category 6−20 years old. The Ear Nose and Throat (ENT) surgery was revealed as surgery with the highest incidence. Regional anesthesia had a higher incidence than general anesthesia. Operation lasting 181−210 minutes was considered as category which PONV mostly occured. Patients receiving nitrous oxide were more likely to experience PONV, and patients who were given neostigmine as muscle relaxant had lower incidence of PONV compared to those who were not.Conclusions: The incidence of PONV was similar to the study presumed earlier and this may influenced by many factors including patients, surgical, and aenesthtical factor. [AMJ.2017;4(1):58–63]DOI: 10.15850/amj.v4n1.1022
Malnutrition in Non-Hodgkin Lymphoma Patients at Dr. Hasan Sadikin General Hospital Bandung
Azizah Puspitasari Ardinal;
Siska Wiramihardja;
Indra Wijaya
Althea Medical Journal Vol 6, No 1 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran
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DOI: 10.15850/amj.v6n1.1521
Background: Non-hodgkin lymphoma (NHL) has the highest prevalence among hematologic malignancies. The prognosis and response to therapy in NHL patients may worsen in the presence of malnutrition. The aim of the study was to describe the malnutrition status in NHL patients. Methods: This was a cross-sectional descriptive study. Nutritional status was assessed using Subjective Global Assessment (SGA) obtained from the medical records of all NHL patients at Dr. Hasan Sadikin General Hospital registered in 2017.Results: In total, there were 78 medical records of NHL patients that fulfilled the inclusion criteria. All NHL patients had experienced malnutrition, categorized as mild-moderate malnutrition (70.5%) and severe malnutrition (29.5%). In NHL patients with mild-moderate malnutrition, 29% had 5–10% weight loss; 60% had suboptimal solid diet; 56.4% experienced anorexia; and 50.9% had subcutaneous fat loss. In NHL patients with severe malnutrition, 78.3% had more than 10% weight loss; 73.9% had suboptimal solid diet; 78.3% experienced anorexia; and 100% had subcutaneous fat loss.Conclusions: Based on subjective assessment, all NHL patients were malnourished and experienced change of food intake and loss of subcutaneous fat, therefore, a better nutritional support scheme are crucial for NHL patients.
Detection of Enteropathogenic Bacteria under Fingernails of Canteen Workers at Universitas Padjadjaran, Jatinangor
Nalinie Nalammah Nahenthran;
Imam Megantara;
Ardini S Raksanagara
Althea Medical Journal Vol 3, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran
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Background: Food poisoning is a major problem in Indonesia as most people do not clean under their fingernails to remove bacteria. This study was designed to detect enteropathogenic bacteria under the fingernails of canteen workers in Universitas Padjadjaran, Jatinangor.Methods: A cross-sectional study was conducted from October−November 2014 at the Faculty of Medicine’s Microbiology Laboratory to detect enteropathogenic bacteria under the fingernails of canteen workers in Universitas Padjadjaran, Jatinangor. Based on the inclusion and exclusion criteria of the study, 30 canteen workers were selected by random sampling from three canteens. Samples were collected from the fingernails of both the right and left hands by using a cotton swab. Sixty specimens were cultured for identification of the enteropathogenic bacteria by using gram staining method and biochemical tests.Results: The highest percentage of enteropathogenic bacteria found under the fingernails of canteen workers was Klebsiella pneumoniae with a percentage of 45% followed by Enterobacter aerogenes with a percentage of 25.7%, Salmonella paratyphii with a percentage of 9.7%, E. coli with a percentage of 6.4%, and Serratia sp, Proteus mirabillis, Klebsiella oxytoca and Shigella sp. with a percentage of 3.2%.Conclusions: The highest number of bacteria found under the fingernails of the canteen workers is Klebsiella pneumoniae, followed by Enterobacter aerogenes, Salmonella paratyphii and E. coli which has potential to cause gastroenteritis if cross-contamination occurs between the fingernails and the food.[AMJ.2016;3(2):309–13]DOI: 10.15850/amj.v3n2.798
Environmental Factor Contributed to The Onset of Schizophrenia
Yuleni Yuleni;
Tuti Wahmurti A. Sapiie;
RA. Retno Ekowati
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran
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DOI: 10.15850/amj.v4n2.1080
Background: Schizophrenia is a severe and chronic mental disorder that needs a long term treatment and social support. This condition may results in burden and disturbance in the family and society A number of studies have investigated some environmental factors that may potentially lead to schizophrenia. One of many suspected environmental factors is place of born or grew up. This study was conducted to investigate association between place of born or grew up and age of onset of schizophrenia.Methods: This analytical study using cross-sectional method was conducted by retrieving data from 72 medical records of hospitalized schizophrenic patients in Dr. Hasan Sadikin General Hospital from October‒November 2013. The variables in this study were age of onset and place (urban or rural) where the patients born or grew-up.The collected data were analyzed using Chi-Square statistical test.Results: This study discovered that 75% of subjects were born or grew up in urban area, 68% of subjects had age of onset at 20‒40 years and there was no association between place of born or grew up and age of onset of schizophrenia (p-value was 0.108).Conclusions: More than half subjects were born and grew up in urban, who had age of onset of schizophrenia at 20‒40 years and there is no significant association between place of born or grew up and age of onset of schizophrenia. DOI: 10.15850/amj.v4n2.1080
Enteric Pathogen Bacteria in Non-Broiler Chicken Egg Shells from Traditional Market and Supermarket, Jatinangor Subdistrict, West Java
Kavita Arumugam;
Sunarjati Sudigdoadi;
Gaga Irawan Nugraha
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran
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Background: Around 1.5 million of children dying annually due to diarrhea. Contaminated food is one of the sources of the diarrhea incidence (food borne diseases). Eggs are one of the least expensive forms of protein which is affordable by the community and is easily to find in either traditional or modern market/supermarkets.The objective of this study was to identify enteropathogenic bacteria contamination on non-broiler (ayam kampung) egg shell and to compare the findings between eggs sold in traditional and modern markets.Methods: This was a descriptive study performed at the Microbiology Laboratory of the Faculty of Medicine, Universitas Padjadjaran. A total of 40 eggs were used, 20 from two traditional markets and 20 from two modern markets. The eggs were swabbed using saline, dipped in tryptic soy broth and streaked on Mac Conkey agar. The collected data were analyzed and presented in tables.Results: Out of 40 samples, there were 19 positive cultures found from the traditional market and 16 from the modern market. There were 30 pink colonies indicating that they were lactose fermented, 5 transparent colonies indicated non-lactose fermentation, 4 showed no colony growth, and 1 grew an unidentified colony. The most found bacteria were Klebsiella sp. and Enterobacter sp. in both market. Conclusions: Eggs shells from traditional and modern markets are contaminated with Enteropathogenic microbes. DOI: 10.15850/amj.v2n3.487
Relationship between Physical Activity and Age on Flatfoot in Children
Carmellia Janice Jasrin;
Wulan Mayasari;
Lulu Eva Rakhmilla
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran
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DOI: 10.15850/amj.v3n3.887
Background: Modern technology has decreased physical activities of most people, especially children. A low physical activity is one of the risk factors of flatfoot. Flatfoot is a flattening of medial longitudinal arch of the foot (MLA) affecting human’s body posture and gait. The objective of this study was to analyze the relationship between physical activity and age on flatfoot.Methods: This study selected 271 children from the elementary school of Cikeruh 1, Jatiroke 1, and Paripurna using cluster random sampling method. Data were collected from August to November 2015. The primary data were collected using questionnaire to determine the physical activity level and footprint method to measure MLA height which was counted using Arch Index (AI). If the AI>0.26, it was considered low arch/flatfoot. Statically, the collected data were analyzed by Fisher’s exact test.Results: From a total of 271, 151 (55.7%) children had a low activity level with 120 of them (44.3%) were flatfoot, whereas in 113 (41.7%) children with an intermediate activity level, 76 children (28.0%) were flatfoot; and from a total of 7 (2.6%) children with a high activity level, 4 children (1.5%) were flatfoot. There was a negative correlation between age and arch index, right foot (r=-1.67;p=0.006), left foot (r=-1.56;p=0.01). This study proved that there was a relationship between the level of physical activity and flatfoot (Fisher=6.125/p=0.040).Conclusions: The Arch Index of the foot becomes smaller with age with an inverse correlation and low physical activities have been proved to have contibution to flatfoot occurrence. [AMJ.2016;3(3):396–400] DOI: 10.15850/amj.v3n3.887
Prophylactic Antibiotic Pattern in Open Reduction Internal Fixation for Closed Fractures at Dr. Hasan Sadikin General Hospital Bandung in 2013
Deviana Suciani Edwiza;
Ike Rostikawati Husen;
Widya Arsa
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran
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Background: Surgical site infection remains a serious complication of a surgery. Prophylactic antibiotics should be used in open reduction and internal fixation to prevent surgical site infection. This study aimed to study the pattern of prophylaxis used in internal fixation of closed fractures as this surgery is considered as a high-risk orthopedic procedures.Methods: This retrospective-descriptive study was performed from August to October 2014. Subject was closed fracture patient who underwent open reduction and internal fixation at Dr. Hasan Sadikin General Hospital Bandung in 2013. Data about characteristics of patients and pattern of the use of prophylactic antibiotics were obtained from patients’ medical record.Results: Medical records from 76 patients who underwent ORIF were analyzed. Sixty eight patients (68.4%) were given 1 gram cefazolin intravenously as preoperative antibiotic prophylaxis. Timing for administration of antibiotics was 30–60 minute preoperatively in 34 (44.2%) patients. All Patients were given postoperative prophylaxis for 4.09 ± 1.36 days in average. The antibiotic most commonly used was cefazolin in 51 (63%) patients. All patients were prescribed an oral antibiotic at discharge. Cefadroxil was the most common antibiotic prescribed for patients at discharge. Conclusions: Cefazolin is the most common preoperative prophylactic antibiotic given to patients. All Patients are given postoperative prophylaxis and prescribed an antibiotic at discharge.
Familial Predisposition of Primary Dysmenorrhea among Senior High School Girl Students
Prema Sharlini;
Hadyana Sukandar;
Ryadi Fadil
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran
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Background: Dysmenorrhea is a common female reproductive problem in women of active reproductive agewhich is characterized by menstrual pain or cramps in a women’s lower abdomen or back. Dysmenorrhea can be classified into primary and secondary. One of the associated risk factor of primary dysmenorrhoeais the family history, however the study on the family history of primary dysmenorrhea with recurrent menstrual pain is limited. This study was conducted to identify the correlation between family history and primary dysmenorrhea in high school girls.Methods: This cross sectional study was conducted at several senior high schools in Jatinangor from April−June 2013. One hundred and sixty two students were included in this study. The sample size was calculated based on the unpaired−dichotomous variable for the two−sided formula. A self administered questionnaire was distributed to the senior high school girl students who were in their menarche age, menstrual cycle characteristics, presence or absence of dysmenorrhea, severity of pain and presence dysmenorrhea in mothers and in sisters were inquired. Data were analyzed using chi square test.Results: Overall, there were association between positive family history and primary dysmenorrhea among the students with (p<0.001). The prevalence of dysmenorrhea in the students was 92.6% with 95% confidence interval which was 87.5−95.7%. The prevalence rate was 67.9% in mothers with 95% confidence interval which is 60.4−74.6% and 80.2% prevalence of primary dysmenorrhoea in sisters with 95% confidence interval which is 73.4−85.6%.Conclusions: There is a significant association between positive family history and primary dysmenorrhea.[AMJ.2015;2(4):579–83] DOI: 10.15850/amj.v2n4.643
Effect of Spondias dulcis Leaves Infusion on Glucose Transport Rate through Rat Intestine Epithelium Cell Membrane
Krisna Destia;
Anna Martiana;
Sylvia Rachmayati
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran
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Background: Nowadays, people consume herbal remedies made from plants which are believed to be able to relieve certain symptoms and restore normal metabolic functions. Golden apple (Spondias dulcis) leaf has the potential to lower blood glucose. The purpose of this experiment was to observe the anti–hyperglycemic effect of S. dulcisleaves infusion on glucose transport rate through intestinal mucosal membrane of Wistar rats.Methods: An experimental study was conducted from October 2013 to November 2014. Nine male Wistar rats were selected aged 12–16 weeks, weighted 250–400 grams, healthy, actively moving, and had never been used in experiments. The rats were anesthetized, cut open and given three kinds of treatments: three kinds of glucose solutions were flowed through the intestinal tract using in situ perfusion method. Samples obtained from the rat’s intestine were measured with a spectrophotometer to obtain glucose rate transported through intestinal membrane from every treatment. The results of condition 1 and 2, and condition 1 and 3 were then compared.Results: The means of glucose transported through rat intestines epithelium cell membrane were 6.43 mg/dl, 9.40 mg/dl and 9.81 mg/dl. Statistic test result showed there was no significant difference on the glucose transported in every treatment.Conclusions: Glucose absorption rate in rat intestine doesnot decrease after they are given S. dulcis leaves infusion. Therefore, this experiment concludes that S. dulcis leaves do not affect the glucose transport rate in rat intestines epithelium cell membrane. [AMJ.2016;3(4):562–5] DOI: 10.15850/amj.v3n4.939