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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Arjuna Subject : -
Articles 1,068 Documents
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Green Tea and its Effect on Hemostasis Measured by Thrombelastography Bryant Alyzandyr Eumhyn Chua; Trully D. Sitorus; Nadjwa Zamalek Dalimoenthe
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Increasing health problems may come from changes in lifestyle including stressful lifestyles, high calorie diets, and lack of physical activity. Those may also lead to an increase occurrence of abnormal hemostasis. Green tea has been well known for its many benefits, including its antithrombotic effect. The aim of this study was to determine whether the consumption of green tea actually affects hemostasis and to measure changes in hemostatic parameters after its consumption.Methods: A preliminary explorative study was conducted on 3 healthy female subjects aged between 21 to 22 years old for 8 weeks from October to November 2012 in Jatinangor, Sumedang, Indonesia. The subjects were subjected to initial thrombelastography analysis and started drinking green tea twice a day after meals. The solution was made by steeping a teabag in 250ml water of 70°C for 2 minutes. After 8 weeks, another thrombelastography analysis was performed to the subjects. Results: Pre- and post-intervention results of the analysis were averaged and compared according to the parameters. The results of this study showed prolonged R (Reaction-time) and K (K-time), decreased α (angle) and MA (Maximum Amplitude), and increased LY30 (lysis at 30 minutes), showing an overall reduction in coagulability. Conclusions: The consumption of green tea twice a day for 8 weeks affects hemostasis with hemostatic parameters measured by thrombelastography show differences before and after consumption.Keywords: Green tea, hemostasis, thrombelastographyDOI: 10.15850/amj.v2n1.426
Basic Training of Student’s Outdoor Club Increases Muscle Mass after Five Weeks of Exercise in Males Novie Salsabila; M. Rizal Chaidir; Setiawan Setiawan
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

   Background:  Aerobic and anaerobic exercises, may lead to increase muscle mass. The aim of this study was to determine the change in muscle mass during basic training of students’ outdoor club.Methods: This was an observational analytic study to college students who joined basic training of students’ outdoor club for 19 weeks. Subjects consisted of 17 male and 15 female students, measured  five times consecutively by using Body Fat/Hydration monitor scale, with Bioelectrical Impedance Analysis principle. Data collection was performed five times,  from February to July 2012 in Bandung. Statistical analysis was processed using Analysis of Variance (ANOVA).Results: The result in males showed the mean 43.35±3.15 on the initial measurement. The muscle mass further increased significantly after five, ten, fifteen, and nineteen weeks of exercise (43.73±3.18 (p<0.05); 44.07±2.97 (p<0.05); 44.08±2.84 (p<0.05); 44.72±2.78 (p<0.05); all data vs 43.35±3.15) respectively. In females, there was increased of muscle mass although not all were statistically significant. The baseline was 37.77±2.00 with increased muscle mass after five, ten, fifteen, and nineteen weeks of exercise (37.78±2.06 (p>0.05); 38.08±1.67 (p>0.05) ; 38.23±1.52 (p>0.05) ; 38.61±1.52 (p<0.05) vs 37.77±2.00) respectively.Conclusion: Basic training of student’s outdoor club increases muscle mass significantly after five weeks of exercise in males, but not in femalesKeywords: Basic training, Bioelectrical Impedance Analysis, hypertrophy, muscle mass, students outdoor clubDOI: 10.15850/amj.v2n1.445 
Nutritional Status of Tetralogy of Fallot Patients at Dr. Hasan Sadikin General Hospital Bandung Gabriella Cafrina; Armijn Firman; Gaga Irawan Nugraha
Althea Medical Journal Vol 3, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Undernutrition is common in children with congenital heart disease (CHD), especially in developing countries including Indonesia. The objective of the study was to describe the nutritional status of children patients with Tetralogy of Fallot.Methods: This was a cross-sectional descriptive study using 41 medical records of children aged 0–14 years old with Tetralogy of Fallot that visited pediatric outpatient department of Dr. Hasan Sadikin General Hospital in period of January to December 2013. The variable was anthropometric measurement, namely weight-for-age, height-for-age, weight-for-height, and body mass index-for-age. These anthropometric data were analyzed using statistics software, WHO Anthro, and WHO AnthroPlus and were classified based on nutritional status according to WHO. The collected data were displayed in percentage.Results: There were more boys (60.98%) who had Tetralogy of Fallot compared to girls (39.02%). The percentage of undernutrition was 39.02% with 43.75% in 5–14 year old children. The percentage of stunting was 70.73% with 72% in 0–5 year old children. Meanwhile, the percentage of underweight was 52% in children aged 0–5 years old.Conclusions: The percentage of undernourished children with Tetralogy of Fallot is quiet high. Undernutrition occurs more often in 5–14 year old children, while stunting occurs more often in 0–5 year old children. [AMJ.2016;3(2):298–303]DOI: 10.15850/amj.v3n2.784
Relationship between Nutritional Status and Flat Foot in Children Joyce Phua Pau Fung; Yoyos Dias Ismiarto; Wulan Mayasari
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Pediatric flatfoot has been reported as the highest clinical complains for foot problems in pediatric department. Nutritional status has showed great influence on the occurrence of flat foot. There are many debates regarding whether underweight or overweight children are more prone to flatfoot. The aim of this study was to analyze the relationship between nutritional status and flatfoot in children.Methods: A cross sectional study was conducted from July to October 2015 in 3 primary schools in Kecamatan Jatinangor. There were 259 children of grade 4 to 5 included in this study. Flatfoot screening was based on measurement of footprint and calculation using Chippaux-smirak index (CSI). The height and weight of children were measured to obtain their Body Mass Index (BMI). Nutritional status was classified based on CDC BMI-for-age growth charts. Analysis was done using chi-square test.Results: There was significant association between nutritional status and flatfoot with p value<0.001.The prevalence of flatfoot in children grade 4to5is40%. When compared to the normal weight children, the overweight children showed prevalence ratio of 1.97(95% CI:1.47 to 2.64) while the underweight children showed prevalence ratio of 1.34 (95% CI:1.78 to 2.25).This stated that the risk of developing flat foot was higher in overweight children.Conclusions: There is significant association between nutritional status with children grade4 to 5. Overweight children are more prone to flat foot. [AMJ.2017;4(1):152–6] DOI: 10.15850/amj.v4n1.1038
Intention for Hepatitis B Vaccination among Male-to-female Transgenders in Bandung Ain Izzati Khiruddin; Irvan Afriandi; Laili Aznur; Elsa Pudji Setiawati
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Hepatitis B is still an alarming global disease nowadays. The majority of transmission is by sexual activity during adulthood and male-to-female transgender is a high risk group. Despite protective vaccine is available, vaccination coverage among these high risk groups remained low. This study aimed to compare the differences in attitude, subjective norms, and perceived behavioral control between the intended group and unintended group for hepatitis B vaccination among male-to-female transgenders in Bandung.Methods: A Cross-sectional study was conducted during September–November 2012 to 100 male-to-female transgenders residing in Bandung. Thirteen Likert scales validated questionnaires were used to compare the attitude, subjective norms and perceived behavioral control by their intention of hepatitis B vaccination (Theory of Plan Behavior/TPB). the respondents were recruited by the help of Srikandi Pasundan, that actively works in the issues of transgender. The inclusion criterias were they regard themselves as waria, consistent as a transgender for at least six months, residing in Bandung, and sexually active within six months. Independent variables consist of demographic characteristics and TPB construct variables. Mann Whitney Test was used to analyze the data.Results: Among 75% of the unvaccinated respondents, majority (70.7%) have the intention to get hepatitis B vaccination. Mann Whitney analysis showed that there is a difference of attitude between the intended group and unintended group for hepatitis B vaccination, while there are no differences by their intention for subjective norms and perceived behavioral control.Conclusion: The attitude influenced vaccination intention among male-to-female transgenders in Bandung. [AMJ.2015;2(1):253–61]
Supplement Consumption among Post stroke Patients in Dr. Hasan Sadikin General Hospital Bandung Annisa Rahayu; Novitri Novitri; Novi Vicahyani Utami
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Stroke is one of the leading causes of global disability. Post stroke rehabilitation program becomes the key to gain functional recovery. Thus it minimizes disabilities. Multiple studies have been carried out to gain greater functional outcomes for post stroke patients, including medical therapy such as supplements. However, supplement effectiveness in providing stroke recovery or prevention is still debatable. There is no data of supplement consumption among post stroke patients; therefore, the aim of this study was to determine the supplement consumption among post stroke patients.Methods: This study was a cross sectional descriptive study using primary data with a consecutive sampling method. Minimum samples for this study were 42 post stroke respondents who followed rehabilitation program. This study was conducted at Physical Medicine and Rehabilitation Clinic of Dr. Hasan Sadikin General Hospital Bandung from June until November 2013. The interviews were done after written informed consent was obtained. Descriptive statistics such as frequency distributin and proportion were used to analyze the data.Results: From 42 respondents, 23 (55%) respondents consumed the supplement. From 34 supplements recorded, 56% were herbs supplements; followed by multivitamin (29%), mineral (6%), multivitamin and mineral (6%), and other supplement (3%). The most frequent ingredients composed in the supplements were B1, B6 and B12 vitamin (7%).Conclusions: More than a half of post stroke patients at Physical Medicine and Rehabilitation Clinic Dr. Hasan Sadikin General Hospital are supplement users, with herbal supplements as the majority. The most frequent ingredients used are B1, B6 and B12 vitamin. [AMJ.2016;3(3):451–8]DOI: 10.15850/amj.v3n3.865
Drug Allergy Clinical Characteristics in Pediatrics R. Devina Fathia Almira; Gartika Sapartini; Vycke Yunivita Kusumah Dewi
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (379.124 KB) | DOI: 10.15850/amj.v4n2.1097

Abstract

Background: A drug allergy causes a morbidity and a mortality due to its various range of clinical manifestation. Unfortunately, a study  focusing in pediatric drug allergy is insufficient, especially in Bandung. Thus, this study is conducted to determine the clinical characteristic of pediatric drug allergy in Dr. Hasan Sadikin General Hospital Bandung.Methods: This study was a retrospective descriptive study using medical records of pediatric drug allergy patients between 2010–2015 in Dr. Hasan Sadikin General Hospital Bandung taken with total sampling method. The variables were patient age, gender, causative drug, and clinical manifestation. Clinical manifestation was then divided into exanthem, urticaria, erythema multiforme, Steven-Johnson’s syndrome/toxic epidemiolytic necrosis (SJS/TEN), and fixed drug eruption (FDE). Results: Out of 101 patients, only 71 were included in the study due to incomplete medical records of the rest. There were 34 (47.89%) males and 37 (52.11%) females. Patients’ age ranged from 1–18 years old with the mean of 7.4 years old. The most common clinical manifestation was SJS/TEN with 25 (35.21%) patients, followed by exanthem with 22 (30.98%) patients. The most common suspected causative drug was non-steriodal anti inflammatory drugs (NSAID) (24%), followed with penicillin (21%).Conclusions: Most common manifestation of pediatric drug allergy in female is SJS/TEN, meanwhile in male is exanthema. Steven-Johnson’s syndrome/toxic epidemiolytic necrosis mostly occurs at the age group of 12–18 years old, and exanthema at the age group of 0–3 years old. This condition is mostly caused by NSAID and penicillin.DOI: 10.15850/amj.v4n2.1097
Solanum muricatum Aiton Juice as A Hepatoprotective Agent in Wistar Rats Induced With Carbon Tetrachloride Justine Sim Wei Yang; Istriati Istriati; Tiene Rostini
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Liver participates in various metabolic processes in human body. Exposures to toxins such as carbon tetrachloride (CCl4) results in hepatocyte destruction and release the cell contents. Enzymes such as serum glutamic pyruvic transaminase (SGPT) were used as a parameter to diagnose liver damage. Pepino (Solanum muricatum Aiton) contains antioxidants that protect liver from hepatoxicity. The aim of this experiment is to determine the effect of pepino in protecting the hepatocyte from hepatotoxic effect of CCl4.Methods: A total of 16 Wistar rats used as the subject were divided into Control and Therapeutic Group. The Control group was induced with CCl4 but was not given pepino juice. Meanwhile, the Therapeutic Group was given pepino juice for 10 days. For induction of hepatotoxicity, CCl4 10% was given at a dosage of 2.0 ml/kg intra-peritoneal. Each Wistar rat in Therapeutic Group was given 1.0 ml of 300 g/ml pepino juice via oral feeding. Spectrophotometer with adjusted wavelength of 340 nm was used to measure SGPT level of the Wistar rats and statistical T-test was used to analyze the data.Results: Wistar rats in Therapeutic group showed a larger decrease (6898.9 IU/L–79.1 IU/L) in SGPT level compared to the Control group (6469.8 IU/L–418.5 IU/L). The SGPT level of the Wistar rat in Therapeutic group reached normal baseline (50 IU/L–150 IU/L). The significance of the experiment was supported by the T-test, P-value <0.05Discussion: Pepino juice had antioxidants that protect the hepatocyte of Wistar rats from free radicals. The synergistic action of antioxidants and hepatocyte regeneration of Wistar rats in Therapeutic group caused a decrease in SGPT level. Therefore, the experiment concluded that pepino juice at the dosage of 300 g/ml has hepatoprotective effect.Key words: Carbon tetrachloride, hepatotoxicity, Pepino, Solanum muricatum Aiton, SGPT DOI: 10.15850/amj.v2n4.484
Allergic Rhinitis Patient Characteristics in Dr. Hasan Sadikin General Hospital Bandung Indonesia Raisa Mentari Moeis; Melati Sudiro; RB. Soeherman Herdiningrat
Althea Medical Journal Vol 1, No 2 (2014)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Allergic rhinitis affects 500 million people worldwide, especially children and adolescents. This disease interferes with daily activities and productivity, leading to decreased quality of life. Allergic rhinitis is often accompanied by co-morbid conditions such as asthma, conjunctivitis, rhinosinusitis, urticaria and othersthat may worsen the disease. This study aimed to investigate the characteristics of patients with allergic rhinitis during the period of 2010-2011 in Dr. Hasan Sadikin General Hospital Bandung.Methods: This study was a descriptive study with a cross-sectional design using medical records of allergic rhinitis patients  who visited the allergy clinic of the Otorhinolaryngology ‒ Head and Neck Surgery ( ORL ‒ HNS ) Department of Dr. Hasan Sadikin General Hospital Bandung.Results: There were 167 patients diagnosed as suffering from allergic rhinitis during the study time with more women (53.3%) affected compared to men (46.7%). Most of them were in the age group of 18-34 years old (52.7%) and their were student (53.3%). Most  were suffered from moderate-severe persistent allergic rhinitis based on the Allergic Rhinitis and its Impact on Asthma-World Health Organization (ARIA-WHO) classification (52.7%). Co-morbid conditions were found in 73.7% of subjects and the allergic conjunctivitis (59.9%) was the most common.Conclusions: Allergic rhinitis is most commonly found in people at school age and productive age. Most allergic rhinitis patients are classified into persistent moderate/severe, showing that the rhinitis symptom has already interfered with their daily activities and decreased their quality of life.Key words: Allergic Rhinitis, Co-morbid Condition, school age  Karakteristik Pasien Rinitis Alergi di Rumah Sakit Dr Hasan Sadikin Bandung Indonesia Abstrak Latar Belakang: Rinitis alergi memengaruhi 500 juta orang di seluruh dunia, terutama anak-anak dan remaja. Penyakit ini mengganggu kegiatan dan produktivitas sehari-hari serta menyebabkan kualitas hidup menurun. Rinitis alergi sering disertai dengan penyakit penyerta seperti asma, konjungtivitis, rhinosinusitis, urtikaria dan lain-lain yang dapat memperburuk penyakit. Penelitian ini bertujuan untuk mengetahui karakteristik pasien dengan riinitis alergi periode 2010-2011 di Rumah Sakit Dr. Hasan Sadikin Bandung.Metode: Penelitian ini merupakan penelitian deskriptif dengan desain potong lintang dengan menggunakan rekam medis pasien rinitis alergi yang mengunjungi klinik alergi Departemen Telinga, Hidung, Tenggorokan - Kepala dan Leher (THT-KL)) RS Dr. Hasan Sadikin Bandung.Hasil: Ada 167 pasien yang didiagnosa menderita rinitis alergi selama usia sekolah. Perempuan lebih banyak yang terkena dampak (53,3%) dibandingkan dengan laki-laki (46,7%). Sebagian besar dari mereka berada di kelompok usia 18-34 tahun (52,7%) dan mereka adalah siswa (53,3%). Berdasarkan klasifikasi Organisasi Allergic Rhinitis and its Impact on Asthma-World Health Organization (ARIA-WHO) (ARIA-WHO) sebagian besar menderita rinitis alergi persisten sedang-berat (52,7%). Kondisi co-morbid ditemukan di 73,7% dari subyek dan yang paling umum adalah konjungtivitis alergi (59,9%).Simpulan: Rinitis alergi paling sering ditemukan pada orang di usia sekolah dan usia produktif. Sebagian besar pasien rinitis alergi diklasifikasikan menjadi persisten sedang/berat. Hal ini menunjukkan bahwa gejala rinitis telah mengganggu kegiatan sehari-hari dan menurunkan kualitas hidup mereka. Kata kunci: Rinitis alergi, Kondisi Co-morbid, usia sekolah DOI: 10.15850/amj.v1n2.350
Knowledge and Attitude on Febrile Seizure among Mothers with Under-Five Children Jihan Alifa Syahida; Nelly Amalia Risan; Vita Murniati Tarawan
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Febrile seizures frequently occur in children under 5 years old and usually create fear and anxiety among parents. Poor understanding of febrile seizure among parents contributes to mismanagement of seizure. The objective of this study was to identify the knowledge and attitude on febrile seizure among mothers of under five children.Methods: This descriptive community-based survey comprised of 96 mothers with under 5 children who were chosen through randomization. This survey was, conducted in Hegarmanah Village, Jatinangor, West Java, Indonesia in October 2013. Data were collected using a questionnaire and analyzed using frequency analysis.Results: Fifty nine respondents (61%) considered that high fever in their children will result in seizure and 63 mothers (65%) stated that this condition was a life-threatening situation which could lead to brain damage (50%) and paralysis (50%). There were some respondents who would manage seizure by shaking (27%) or holding the child tightly during seizure (22%) and putting spoon into the children mouth (59%). Sixty respondents (62.5%) prevented febrile seizure by giving them coffee.Conclusions: Knowledge and attitude regarding febrile seizure is good, but the knowledge and attitude towards the outcome and what to do during febrile seizures occasion are still poor. [AMJ.2016;3(4):649–54] DOI: 10.15850/amj.v3n4.954

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