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Althea Medical Journal
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Arjuna Subject : -
Articles 1,068 Documents
Level of Knowledge about Hypertension in Cilayung Village District Jatinangor, Sumedang Dian Qisthi; Guswan Wiwaha; Abdul Hadi Martakusumah; Elsa Pudji Setiawati
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (684.484 KB)

Abstract

  Background: Hypertension known as a silent killer because it is often asymptomatic and causes target organ damage. Prevention of hypertension and its complications are pharmacological and non-pharmacological therapy, making holistic knowledge of hypertension is paramount to establish good behavior. This is needed by hypertensive and non-hypertensive individuals. Therefore, the study was conducted to identify any knowledge level differences between hypertensive and non-hypertensive groups. Methods: Respondents were 116 Cilayung residents equally divided in hypertensive and non-hypertensive groups. Respondent’s blood pressure was measured and they completed questionnaires during October 2012. This is an observational analytic cross-sectional study with chi-square test.Results: The respondents’ characteristics in both groups dominated by females, aged 50-59 years, housewives, with elementary school background. Most respondents in both groups had sufficient knowledge about hypertension in general, but for knowledge about risk factors, treatment, and complications were still not enough. The result of the chi-square test was not significant with P=0.676. It was due to distributed health promotion and non-matched respondents’age.Conclusion: There is no difference in level of knowledge about hypertension between both groups in Cilayung.Keywords: Differences, hypertension, level of knowledge DOI: 10.15850/amj.v2n1.449 
Quality Of Life of Laryngeal Carcinoma Patients after Total Laryngectomy Achmad Prihadianto; Yussy Afriani Dewi; Agung Dinasti Permana
Althea Medical Journal Vol 6, No 2 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.104 KB) | DOI: 10.15850/amj.v6n2.1689

Abstract

Background: Management of laryngeal carcinoma has been widely developed, either by surgery, radiotherapy, and/or chemotherapy. The treatment has a major impact on physical, social, and psychological health that can change the quality of life of patients. This study aimed to determine the quality of life of laryngeal carcinoma patients after total laryngectomy.Methods: This descriptive study was conducted from May to August 2018. Patients with post total laryngectomy at the Division of Ear, Nose, Throat, Head and Neck Surgery, Dr. Hasan Sadikin General Hospital, Bandung were recruited. Short Form 36 (SF-36) Study Questionnaire and the European Organization for Research and Treatment of Cancer Head and Neck Cancer Quality of Life Questionnaire (EORTC QLQ-H & N35) were used, and data were presented in the form of descriptive narratives and tables.Results: In total, 23 patients were included consisting of 19 men (82.61%) and women (17.39%), aged 56-65 years old. The mean score of quality of life in physical components of SF-36 was 87.55 ± 2.35 and in mental components was 85.35 ± 3.92. The highest score of quality of life of EORTC QLQ-H & N35 on the speech problem scale was 51.69 ± 6.36. Conclusion: The quality of life of laryngeal carcinoma patients after total laryngectomy is generally good, however, speech is the main problem and needs to be further elaborated to enhance the quality of life.
Serum Calcium Levels in Chronic Kidney Disease Patient Stratified By Body Mass Index Anthoni Anthoni; Rudi Supriyadi; Siti Nur Fatimah
Althea Medical Journal Vol 6, No 2 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1140.927 KB) | DOI: 10.15850/amj.v6n2.1516

Abstract

Background: Most of the chronic kidney disease (CKD) patients have low blood calcium levels, yet hypercalcemia has a worse outcome in CKD patients. Interestingly, CKD patients with higher body mass index (BMI) have better outcomes. This study aimed to elucidate the difference in blood calcium levels stratified by BMI categories in patients with CKD.Methods: The study was conducted using a comparative analytical cross-sectional study design. Patients with CKD (n100), aged over 18 years old were included, Patients with the following were excluded: the history of hemodialysis, history of antioxidants, calcium and vitamin D supplement consumption, history of infection and malignancy. BMI of patients was categorized into underweight (<18.5 kg/m2), normal (8.5-22.9 kg/m2), and overweight or obese (≥23 kg/m2). Data were analyzed to compare blood calcium in different categories of BMI (Kruskal-Wallis test). Results: The age of patients with CKD included in this study had median age of 61 years old, predominantly was men (57%). The blood calcium level of CKD patients was on the lower border of the normal range. Median BMI was 23.48 kg/m2, of which 53% was categorized as overweight or obese. There was a trend that overweight/obese patients had higher blood calcium levels than underweight and normal-weight patients, however, no statistically significant difference between the BMI category (p=0.982).Conclusions: The blood calcium level in chronic kidney disease varies across the BMI category, however, no correlation with the BMI.
Isolation of Methicillin Resistant - Staphylococcus aureus in Midwifery Students Faculty of Medicine Universitas Padjadjaran September–December 2012 Robinee Panirchelvam; Imam Megantara; Melati Sudiro
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (699.217 KB)

Abstract

Background: Methicillin Resistant-Staphylococcus aureus (MRSA) is resistant bacteria to certain types of beta-lactam antibiotics. Commonly, the MRSA infection is acquired in hospitals, long-term care facilities, or similar institutional settings. Mid-wives are one of the health professional that have a major risk to get MRSA infection and could lead the infection among patients. This research is aimed to identify MRSA among the midwifery studentsMethods: A descriptive study was conducted from September–December 2012 at the Microbiology laboratory to identify the proportion of MRSA among the mid-wife students from Faculty of Medicine, Universitas Padjadjaran. Twenty-five samples were chosen using simple random sampling based on their registration number. The inclusion criterias were healthy students, and 18 to 22 years old. Both nostrils were sampled with a sterile culture swab on both the subject’s nostrils. Gram staining was done in order to identify the gram positive bacteria, Staphylococcus aureus. The samples were inaculated in Mannitol salt agar (MSA), incubated for 24 hours and at 37 ̊ C. After 24 hours, catalase and coagulase tests were done. Moreover, for the susceptibility testing, the chosen media for this study was Mueller Hinton Agar (MHA) and with 30μg Cefoxitin disk. After incubation, the zone of inhibition of the colony less than ≤ 21mm was considered resistant to methicillin.Results: Colonization of MRSA was about 3 out from 25 samplesConclusions: The MRSA colonization in the anterior nasal does exist in midwife students, a further study with more samples should be conducted. [AMJ.2015;2(1):204–7]
The Risk Factors and Collateral System in Coronary Artery Disease among Patients in Bandung Gabriella Graziani; Toni M. Aprami; R. B. Soeherman
Althea Medical Journal Vol 6, No 3 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (61.876 KB) | DOI: 10.15850/amj.v6n3.1726

Abstract

Background: The slow blood flow may cause atherosclerotic plaque, leading to an obstruction in the arterial circulation, and thus resulting in among others myocardial ischemia. There are many risk factors associated with the collateral system such as dyslipidemia, obesity, hypertension, diabetes mellitus, and smoking habit. This study aimed to determine the association between risk factors and collateral system in patients in Bandung. Methods: This was an analytical cross-sectional study, using data of 186 medical records taken from Dr. Hasan Sadikin General Hospital in October 2013. The risk factors were assessed and the prevalence ratio reflected the association between the risk factors and the collateral system was analyzed.Results: The study revealed no significant association between each risk factor and the collateral system, including obesity (p=0.690), smoking (p=0.175), dyslipidemia (p=0.747), and diabetes mellitus (p=0.616); however, only hypertension was associated (p=0.020). Furthermore, no significant association was found between the number of risk factor and the collateral system (p=0.233).Conclusions: Of the risk factors published, only hypertension is a significant risk factor among patients in Bandung, while others including obesity, smoking, dyslipidemia and diabetes mellitus are not associated. Further study needs to be performed to explore other risk factors in coronary artery disease, and to prevent the disease among the population.  
Relationship between Short Term Memory and Cardiopulmonary Fitness of Administrative Officers at Universitas Padjadjaran Iswaran Ampalakan; Ambrosius Purba; Sunaryo Barki Sastradimaja
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: The work of administrative officers depends a lot on their capability in memorizing. Increased fitness is strongly associated with a better memory. This study was conducted to determine the relationship between cardiopulmonary fitness and short term memory.Methods: This analytical cross sectional study was carried out from August to September 2014. Subjects from administrative offices within Universitas Padjadjaran were chosen by simple random sampling. 101 individuals were selected, comprising of 68 males and 33 females. Data were obtained through Digit Span Test for short term memory and the cardiopulmonary fitness was measured using Harvard Step Test. The VO2 Max obtained was correlated with the Digit Span Test score.Results: The mean for cardiopulmonary fitness of males was found to be 36.1, with standard deviation 8.63, whereas mean cardiopulmonary fitness for females was found to be 32.94, with standard deviation 7.5. For correlation analysis, the result of Spearman’s rank analysis from the study showed that the p-value is 0.00. Comparing to the significance level α=5%, the p value is worth less, thus the null hypothesis, Ho is rejected. Therefore, it could be concluded that there was a relationship between cardiopulmonary fitness and short term memory of male and female administrative officers at Universitas Padjadjaran.Conclusions: There is a relationship between cardiopulmonary fitness and short term memory of male and female administrative officers at Universitas Padjadjaran. [AMJ.2016;3(1):34–7] DOI: 10.15850/amj.v3n1.693
Annona Muricata L Leaf Infusion Effect on Glucose Absorption in the Intestinal Cells Membrane of Wistar Rats Model Vycke Yunivita; Putra Haqiqie Adnantama Lubis; Augusta Y. L. Arifin
Althea Medical Journal Vol 6, No 2 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (495.52 KB) | DOI: 10.15850/amj.v6n2.509

Abstract

Background: Diabetes mellitus (DM) is a chronic disease that disrupts the homeostasis of glucose. DM is the second of most causes of deaths in urban areas, as well as the sixth in rural areas. Therefore, herbal medicine is constantly developed. Soursop leaves have been long known to have good effects in lowering glucose levels in our blood. This study explored the soursop leaves infusion on glucose absorption in the intestinal cell membrane of the Wistar Rats Model. Methods: This was an exploratory study performed in October 2012 on five male rats Wistar, aged 3-4 months, weighing about 150-300 grams. Using the in situ perfusion method, each rat was given the following; 3 X 10-3 M glucose solution for one hour; 3 X 10-3 M glucose solution with 1 mL of infusion of soursop leaves (Annona muricata L) for one hour; 3 X 10-3 M glucose solution for the last hour. The glucose absorption levels were measured using spectrophotometry method. The glucose level between treatments was analyzed using a paired sample t-test.Results: The concentration of glucose absorption was decreased, the first treatment was 24.42+14.29 mg/dL, the second treatment was 18.63+10.37 mg/dL, and the third treatment was 18.24+8.02mg/dL), however, the decrease of glucose absorption was statistically not significant.Conclusions: There is a slightly decreased of the glucose absorption in the intestinal cell membranes of the Wistar Rats Model after infusion of soursop leaves. Further study is needed to explore the role of soursop leaves infusion in glucose absorption.
Antituberculosis Drug-induced Hepatotoxicity in Pediatric Tuberculosis Vycke Yunivita; Muhammad Iqbal; Adi Utomo Suardi
Althea Medical Journal Vol 6, No 3 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (363.166 KB) | DOI: 10.15850/amj.v6n3.1673

Abstract

Background: Hepatotoxicity is the most serious side effect caused by using oral antituberculosis (OAT) drugs. This study was performed to determine the characteristics of patients who had antituberculosis drug-induced hepatotoxicity (ADIH) among pediatric inpatient with pulmonary tuberculosis.Methods: This was a cross-sectional study with a total sampling of medical records taken from January–December 2012, including pediatric pulmonary tuberculosis inpatients aged <14 years old at the Department of Child Health of Dr. Hasan Sadikin General Hospital Bandung. The inclusion criteria were children with pulmonary tuberculosis who received OAT drugs. Patients with liver disease were excluded. Data on alanine and aspartate aminotransferase were collected and an increased level of serum aminotransferase was designated as hepatotoxicity.Results: In total, 86 medical records were obtained of whom 24 had ADIH, predominantly occurred in girls (71%), aged 5–9 years old (42%) and in the intensive phase of therapy (58%). Elevated serum alanine aminotransferase (58%), aspartate aminotransferasen (92%), and bilirubin (0.8%) were found. Malnutrition (46%) was common. The difference indeviation of liver function was statistically significant (p<000) between subjects with and without ADIH.Conclusions: Hepatotoxicity is most prominent in patients with malnutrition, girls aged 5–9 years old and in the intensive phase of therapy. Children with malnutrition during antituberculosis therapy are suggested to have a periodic liver function test monitoring to prevent the development of ADIH. 
Congenital Heart Disease Characteristics in Low Birth Weight Infants at Dr. Hasan Sadikin General Hospital in 2010–2014 Villia Damayantie; Sri Endah Rahayuningsih; Irvan Afriandi
Althea Medical Journal Vol 6, No 3 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (7394.594 KB) | DOI: 10.15850/amj.v6n3.1533

Abstract

Background: Congenital heart disease (CHD) is a multifactorial disease defined as an anomaly in the macroscopic structure of the heart that may cause functional disorders. The incidence of CHD is reported higher in infants with low birth weight (LBW) than the entire population of neonates. This study aimed to describe the characteristics of CHD in infants born with LBW.Methods: This was a retrospective descriptive study with a cross-sectional design, performed in October–November 2015. Data were obtained from medical records of inpatients infants at Dr. Hasan Sadikin General Hospital, Bandung in the period of 2010–2014. The data presented were the characteristics of CHD in LBW infants.Results: Of 364 LBW infants treated in the hospital within 5 years period, 21 infants (14 girls and 7 boys) were diagnosed as CHD, with birth weight group predominantly (n18; 85.7%) in the range of 1,500–2,499 gr. Non-cyanosis CHD was prevalent in 95.2% (n20),and patent ductus arteriosus (PDA)was found in 76.1% (n16). Comorbid conditions mostly found in this study were preterm birth (n17), sepsis (n10), and neonatal hyperbilirubinemia (n9).Conclusions: The most common type of CHD in low birth weight infants in Dr. Hasan Sadikin General Hospital is Patent Ductus Arteriosus. The presence of congenital heart disease should be considered in low birth weight infants, thus it is essential to perform screening for early recognition. 
Pharmacological Treatment Pattern and Comorbidities in Parkinson’s Disease Outpatients at Dr. Hasan Sadikin General Hospital Bandung in 2013–2018 Elke Feliciana; Paulus Anam Ong; Sobaryati Sobaryati
Althea Medical Journal Vol 6, No 2 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (29.696 KB) | DOI: 10.15850/amj.v6n2.1513

Abstract

Background: Parkinson’s disease (PD) is one of many neurodegenerative diseases with symptomatic management, and with the correct pattern of pharmacological treatment PD may have an improved quality of life for a minimum of three years. This study aimed to illustrate treatment patterns and comorbidities in PD patients at Dr. Hasan Sadikin General Hospital, Bandung.Methods: This study was a cross-sectional descriptive study by using total medical records of the period of 2013 to 2018. PD patients receiving pharmacological treatments such as levodopa, anticholinergics, dopamine agonists, or combined therapy were included. Patients with incomplete data and with the previous history of other neurological diseases before PD were excluded from this study.Results: In total, there were 57 patients with PD, of whom most of them were males (79%). Age-wise, PD was most common in 60 to 69-year-olds (32%). The most commonly used treatment pattern was the administration of levodopa (33%). Patients aged younger than 30 years were administered anticholinergics, whereas the older patients (>60 years old) mostly were given levodopa. Comorbidities after PD diagnosis were mostly stroke, dementia, and epilepsy.Conclusions: Males are most affected by PD, and the most commonly used treatment pattern is levodopa monotherapy. PD is most commonly found in patients aged 60 to 69 years. Patients aged below 30 years are administered anticholinergics. The most common comorbidities found are a stroke, followed by dementia and epilepsy. By recognizing the patterns and comorbidities of this disease, the study may provide some insights into choosing the most effective pharmacological therapy for PD. 

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