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INDONESIA
Indonesian Journal of Urology
Published by Universitas Airlangga
ISSN : 0853442X     EISSN : 23551402     DOI : 10.32421
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The aim of Indonesian Journal of Urology is to encompass the whole spectrum of urology. The journal publishes papers on a wide range of urological issues such as oncology, functional urology, reconstructive urology, laparoscopy, robotic surgery, endourology, female urology, andrology, pediatric urology, and sexual medicine. We welcome authors for original article (research), review article, interesting case reports, special article, clinical practices, and medical illustrations that focus on the clinical area of urology.
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Articles 498 Documents
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COMPARISON OF PAIN PERCEPTION BETWEEN INTRAVENA TRAMADOL INJECTION WITH PERIPROSTATIC LIDOCAINE INJECTION IN TRANSRECTAL ULTRASONOGRAPHY GUIDED PROSTATE BIOPSY PATIENT Sawal, Zuhri; Djatisoesanto, Wahjoe; Djojodimedjo, Tarmono
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.646

Abstract

Objective: To compare the pain perception between intravenous tramadol administration and PNB technique using lidocaine in TRUS guided prostate biopsy. Material & Methods: The design of this study is a prospective randomized clinical trial. The population of this study is BPH patients who will undergo TRUS guided prostate biopsy procedure according to the indication in our center. Randomization was done for the determination of groups 1 and 2. Group 1 was given tramadol injection 100 mg intravenously, while group 2 was given a local injection of lidocaine periprostatic. The Wong-Baker scale directly determined pain perception during the procedure. Results: The total samples in this study were 20 samples that met the inclusion and exclusion criteria with 10 samples in each group. The lidocaine group had a lower Wong Baker’s pain scale in both probe USG insertion and prostate biopsy than the tramadol group. However, it’s not statistically significant (p=0.089; p=0.125, respectively). Conclusion: The use of intravenous tramadol can be used as an alternative anesthetic/analgesic method in prostate biopsy patients. The pain scale of the intravenous tramadol can be compared with periprostatic lidocaine with lesser complications compared to periprostatic lidocaine.
THE EFFECT OF VITAMIN E (α- TOCOPHEROL) AS NEPHROPROTECTOR ON BLOOD UREA NITROGEN AND SERUM CREATININE LEVEL OF STRAIN WISTAR RATS AFTER CISPLATIN TREATMENT: IN VIVO STUDY Affandi, Yohan; Djatisoesanto, Wahjoe; Hakim, Lukman
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.649

Abstract

Objective: To analyze the differences in kidney function of Wistar strain rats that received a combination of vitamin E and cisplatin, compared with cisplatin alone. Material & Methods: An experimental prospective study with post-test only control design, using male Wistar strain rats (Rattus norvegicus). Rats were randomized using the simple randomized sampling method. Treatment was given in the form of exposure to cisplatin 5 mg/kg (positive control group), with a combination of vitamin E 100 mg/kg and 200 mg/kg (treatment group), to evaluate its effect on kidney function as measured by blood urea nitrogen (BUN) and creatinine serum. Results: Statistical analysis of Mann Whitney showed that there were no differences in BUN levels in the positive control group (cisplatin 5 mg/kg) against each treatment group (p>0.05). Further analysis showed that there was no significant difference between treatment group 1 (Vitamin E 100 mg/kg) and treatment group 2 (Vitamin E 200 mg/kg). There was no difference in serum creatinine levels in the positive control group compared to a treatment group that received both vitamin E 100 mg/kg and the vitamin E 200 mg/kg (p>0.05). further analysis revealed no significant difference in serum creatinine levels between the group that receives vitamin E 100 mg/kg and 200 mg/kg. Conclusion: Vitamin E at doses of 100 mg/kg and 200 mg/kg did not have the nephroprotective feature in cisplatin-exposed Wistar rats.
THE EFFECT OF VITAMIN E (α- TOCOPHEROL) AS NEPHROPROTECTOR ON BLOOD UREA NITROGEN AND SERUM CREATININE LEVEL OF STRAIN WISTAR RATS AFTER CISPLATIN TREATMENT: IN VIVO STUDY Affandi, Yohan; Djatisoesanto, Wahjoe; Hakim, Lukman
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.649

Abstract

Objective: To analyze the differences in kidney function of Wistar strain rats that received a combination of vitamin E and cisplatin, compared with cisplatin alone. Material & Methods: An experimental prospective study with post-test only control design, using male Wistar strain rats (Rattus norvegicus). Rats were randomized using the simple randomized sampling method. Treatment was given in the form of exposure to cisplatin 5 mg/kg (positive control group), with a combination of vitamin E 100 mg/kg and 200 mg/kg (treatment group), to evaluate its effect on kidney function as measured by blood urea nitrogen (BUN) and creatinine serum. Results: Statistical analysis of Mann Whitney showed that there were no differences in BUN levels in the positive control group (cisplatin 5 mg/kg) against each treatment group (p>0.05). Further analysis showed that there was no significant difference between treatment group 1 (Vitamin E 100 mg/kg) and treatment group 2 (Vitamin E 200 mg/kg). There was no difference in serum creatinine levels in the positive control group compared to a treatment group that received both vitamin E 100 mg/kg and the vitamin E 200 mg/kg (p>0.05). further analysis revealed no significant difference in serum creatinine levels between the group that receives vitamin E 100 mg/kg and 200 mg/kg. Conclusion: Vitamin E at doses of 100 mg/kg and 200 mg/kg did not have the nephroprotective feature in cisplatin-exposed Wistar rats.
THE EFFECT OF VITAMIN E (α-TOCOPHEROL) TO TNF-α SERUM LEVELS IN WISTAR WHITE STRAIN RATS EXPOSED TO CISPLATIN Muhammad Shidqy, Eldien; M. Soebadi, Doddy; Hakim, Lukman
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.651

Abstract

Objective: To analyze the protective effect of vitamin E on TNF-α levels in white Wistar strains exposed to Cisplatin. Material & Methods: The design of this study was an experimental laboratory with post-test only control group design, with the evaluation of TNF-α levels carried out after the animals were treated. The grouping of experimental animals was carried out by randomization. This study using male Wistar white rats as samples. The control group in this study included a negative control group (CN), which was given an injection of 1 cc intravenous normal saline 0.9% on the 7th day as a placebo, then on the 10th day the blood sample was taken. The positive control group (CP), which was given cisplatin treatment at a dose of 5 mg/kg intraperitoneally, once on the 7th day. Treatment group (P1) was treated using cisplatin 5 mg/kg intra-peritoneally and Vitamine E 100 mg/KgBW, and Treatment group (P2) was treated using cisplatin 5 mg/kg intra-peritoneally and Vitamine E 200 mg/KgBW. Blood samples were taken on the 10th day, intra-cardiac and TNF-α levels were analyzed using ELISA. Results: There were significant differences in the mean TNF-α levels in the negative control group for all treatment groups with a p-value <0.05. There was also a significant difference in TNF-α levels in the positive control group for treatment group 1 and treatment 2 with p<0.05. On the other hand, further analysis showed that there was no significant difference between treatment group 1 and treatment group 2 (p>0.05). Conclusion: TNF-α levels in mice given cisplatin was much higher compared with the control group. Vitamin E 100 and 200 mg/kgBW cause a decrease in TNF-α protein levels in mice injected with cisplatin when compared with controls. There is no difference in TNF-α levels in mice receiving vitamin E at doses of 100 and 200 mg/kgBW
THE EFFECT OF VITAMIN E (α-TOCOPHEROL) TO TNF-α SERUM LEVELS IN WISTAR WHITE STRAIN RATS EXPOSED TO CISPLATIN Muhammad Shidqy, Eldien; M. Soebadi, Doddy; Hakim, Lukman
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.651

Abstract

Objective: To analyze the protective effect of vitamin E on TNF-α levels in white Wistar strains exposed to Cisplatin. Material & Methods: The design of this study was an experimental laboratory with post-test only control group design, with the evaluation of TNF-α levels carried out after the animals were treated. The grouping of experimental animals was carried out by randomization. This study using male Wistar white rats as samples. The control group in this study included a negative control group (CN), which was given an injection of 1 cc intravenous normal saline 0.9% on the 7th day as a placebo, then on the 10th day the blood sample was taken. The positive control group (CP), which was given cisplatin treatment at a dose of 5 mg/kg intraperitoneally, once on the 7th day. Treatment group (P1) was treated using cisplatin 5 mg/kg intra-peritoneally and Vitamine E 100 mg/KgBW, and Treatment group (P2) was treated using cisplatin 5 mg/kg intra-peritoneally and Vitamine E 200 mg/KgBW. Blood samples were taken on the 10th day, intra-cardiac and TNF-α levels were analyzed using ELISA. Results: There were significant differences in the mean TNF-α levels in the negative control group for all treatment groups with a p-value <0.05. There was also a significant difference in TNF-α levels in the positive control group for treatment group 1 and treatment 2 with p<0.05. On the other hand, further analysis showed that there was no significant difference between treatment group 1 and treatment group 2 (p>0.05). Conclusion: TNF-α levels in mice given cisplatin was much higher compared with the control group. Vitamin E 100 and 200 mg/kgBW cause a decrease in TNF-α protein levels in mice injected with cisplatin when compared with controls. There is no difference in TNF-α levels in mice receiving vitamin E at doses of 100 and 200 mg/kgBW
ADVANTAGES AND DISADVANTAGES OF MALE CIRCUMCISION TECHNIQUES: A LITERATURE REVIEW Andersen; Shannen, Felicia Adelina; Mataram, Ridwan
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.557

Abstract

Objective: To compare the advantages and disadvantages of male circumcision techniques. The articles of male circumcision techniques were investigated from October 2018 to December 2018 through Google Scholar and Proquest. Material & Methods: There are various methods of circumcision, these methods can be grouped into two: using shield and clamp devices and conventional methods (dorsal slit and excision). Results: The result from this review article are the technique using shield and clamp devices such as the Smart Klamp have several advantages, that are minimal bleeding, rarely injuring the glans penis and faster, but the disadvantage is taken more costs, and often occurs edema in the circumcision area. Conclusion: In general, the circumcision method using shield and clamp devices is more beneficial and more practical than conventional methods.
PREDICTIVE VALUE OF SERUM PROSTATE SPECIFIC ANTIGEN IN DETECTING BONE METASTASIS IN PROSTATE CANCER Danarto, Raden; Astuti, Indwiani; Haryana, Sofia Mubarika
Indonesian Journal of Urology Vol 28 No 2 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i2.570

Abstract

Objective: We determine the utility of Prostate Specific Antigen (PSA) for predicting the presence of skeletal metastasis on Bone Scan (BS) in prostate cancer patients. Material & Methods: Retrospective analysis of medical records of 70 consecutive prostate cancer patients subjected to bone scan during the last 2 years was done. 5 cases were excluded due to the following reasons: Serum PSA not available, hormonal or other therapy given prior to serum PSA measurement, and/or Bone Scan, and symptomatic for bone metastasis. In remaining 65 cases, PSA value and bone scan were evaluated. Results: BS was found to be positive in 20/65 (31%) and negative in 45(69%) patients. 24 (37%) had serum PSA > 100 ng/ml, 25 (38.5%) had PSA of 20‐100 ng/ml and only 16 (24.5%) had PSA < 20 ng/ml. Conclusion: Serum PSA < 20 ng/ml have high predictive value in ruling out skeletal metastasis. Our data are in corroboration with results from previous studies that BS should be performed only if PSA > 20 ng/ml. Using this cut‐off, unnecessary investigation can be avoided. Avoiding BS asymptomatic in this group of patients would translate into a significant cost‐saving and reduction in their psychological and physical burden.
INTER-OBSERVER AGREEMENT IN INTERPRETING UROFLOWMETRY MEASUREMENTS IN INDONESIA Suyadnya, I Made; Sigumonrong, Yacobda
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.587

Abstract

Objective: We evaluated the comparability and repeatability of analyses based on uroflowmetry reports among urologists in Indonesia. Material & Methods: We assessed the inter-observer agreement when interpreting urodynamic examinations. Four urologists analyzed 20 sets of uroflowmetry data and gave their interpretations of the normality of the curve, reason of abnormality, grade classification, and pattern of the uroflowmetry curves. The consensus among observers was analyzed using the kappa statistic. Results: The kappa values for the analyses of the normality of the curves indicated fair to the moderate agreement. Agreement on the reason of abnormality showed poor to fair consensus. The shape of the flow curve had kappa values ranging from 0.047 to 0.225, indicating poor to fair consensus. Based on grade also showed kappa value from 0.047 to 0.169, indicating a poor agreement. Conclusion: Interpretations of uroflowmetry tracings showed only the poor to a fair agreement despite the normality of the uroflow curve. Variability in interpretation can strongly impact patient treatment. Therefore, further work is needed to standardize the reporting and interpretation of uroflowmetry studies to optimize patient care.
THE CHARACTERISTIC OF ERECTILE DYSFUNCTION AMONG TYPE 2 DIABETES MELLITUS MALE IN EASTERN INDONESIA Zulfiqqar, Andy; Anthonius, Franky Renato; Cyko, Prasetyo Amanda; Nandana, Pandu Ishaq; Yuri, Prahara; Brodjonegoro, Sakti R
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.603

Abstract

Objective: To determine Type-2 diabetic patients and its characteristics to determined risk of Erectile dysfunction (ED) and the role of EHS score as more practical tools to screening ED among T2DM patients. Material & Methods: The cross-sectional observational study was carried out at the Internal medicine Unit of Manambai Abdulkadir and Dompu district Hospital, out of 45 patients were included on this study. The data were collected from June 01 – August 01 2017. A structural questioner was used to collect the data and was analyzed using SPSS 2.0. person analysis correlation and logistic regression were used to find the Odds Ratio (OR). Results: We found that 38 out of 45 (84.4%) patients (mean age 57.2 ± 7.1) have Erectile dysfunction, 26 patients uncontrolled diabetes, 5 (11.1%) treated as CHF, 4 (8.9%) CKD, and 7 (15.6%) neuropathy diabetic. There is high correlation between random glucose level and IIEF-5 score (r=0.5, p=0.01). The overall odd ratio of ED in this studies was 4.3 (95% CI: 0.73 to 25.1) for uncontrolled diabetes, 2.5 (95% CI: 0.1 to 51.1) for Treated CHF, 2 (95% CI: 0.01 to 41.6) for CKD, and it was 1.2 (95% CI: 0.1 to 11.5) for neuropathy diabetics. Conclusion: From this study, we found that most diabetic patients have ED, and there is high correlation between random glucose level and simplified IIEF-5 score, EHS performed similar result on diagnoses ED compared to IIEF-5.
FIVE YEARS CHARACTERISTIC OF URETHRAL TRAUMA IN TERTIARY HOSPITAL IN WEST JAVA FROM 2013-2017 Agung Nugroho, Tri Sunu; Adi, Kuncoro
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.619

Abstract

Objective: In this study, we try to describe the characteristics of patients with urethral trauma in Hasan Sadikin Hospital Bandung from 2013 to 2017. Material & Methods: The data were taken retrospectively from medical records in the Department of Urology with the permission of the ethical committee. The patient characteristics were then classified according to their age, etiology of trauma, location of trauma, grade of trauma, associated trauma, and initial management. Results: The number of trauma cases in Hasan Sadikin Hospital during 2013-2017 was 20.489, 477 of which (2.33%) were urogenital trauma. Of the total urogenital trauma, there were 124 patients with urethral trauma, male patients were more common (84.67%), with an average age of 34.67 (1-82) years. Seventy two patients (58.06%) were iatrogenic trauma (catheter instrumentation 44.35%, circumcision 6.45%, and others 7.25%), and fifty two patients (41.94%) were non-iatrogenic trauma (traffic accident 31.45%, falls from a height 7.25%, and occupational accident 3.22%). In non-iatrogenic trauma group, 40 patients (76.92%) had posterior urethral trauma and 12 patients (23.08%) had anterior urethral trauma. We found 22 (42.31%) of 52 patients with non-iatrogenic trauma were AAST grade I-II and 30 patients (57.69%) were AAST grade III-V. In patients with posterior urethral trauma, 25 patients (62.5%) had pelvic fractures. There were 10 patients (19.23%) who underwent primary endoscopic realignment within the first 72 hours while 30 patients (57.69%) underwent delayed urethroplasty 3 months after trauma, and the rest (23.08%) were treated conservatively. Conclusion: Urethral trauma in males occurs more frequently than in females. with the most common cause were catheter instrumentation (iatrogenic) and traffic accidents (non iatrogenic). Posterior urethral traumas had higher incidence than anterior urethral traumas, which were commonly associated with pelvic fractures.

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