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INDONESIA
Indonesian Journal of Urology
Published by Universitas Airlangga
ISSN : 0853442X     EISSN : 23551402     DOI : 10.32421
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The aim of Indonesian Journal of Urology is to encompass the whole spectrum of urology. The journal publishes papers on a wide range of urological issues such as oncology, functional urology, reconstructive urology, laparoscopy, robotic surgery, endourology, female urology, andrology, pediatric urology, and sexual medicine. We welcome authors for original article (research), review article, interesting case reports, special article, clinical practices, and medical illustrations that focus on the clinical area of urology.
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Articles 498 Documents
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FIVE YEARS CHARACTERISTIC OF URETERAL TRAUMA IN TERTIARY HOSPITAL IN WEST JAVA FROM 2013-2017 Tambah, Adi Bachtiar; Adi, Kuncoro
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.620

Abstract

Objective: This study aims to determine the characteristics of trauma patients, especially ureteral trauma in Hasan Sadikin General Hospital and expected to be used as data for trauma nationally. Material & Methods: This study was descriptive. Retrospective data collection is taken from medical records of ureteral trauma from 2013 until August 2017 at Hasan Sadikin General Hospital, Bandung. The data obtained are gender, mechanism of trauma, and management of ureteral trauma. Results: A total of 20489 cases of trauma handled in Hasan Sadikin General Hospital, 2.3% is a case of urogenital trauma and 40 of which are cases of ureteral trauma (0.19%). Most ureteral trauma patients are female (90%). Based on the trauma mechanism, 39 patients iatrogenic trauma (97.5%) and 1 patient gunshot wounds (2.5%). From iatrogenic ureteral trauma, 36 patients (90%) had iatrogenic trauma from the gynecological procedure, 5% as a result of the urological procedure, and 2.5% due to gastrointestinal procedure. Management of ureteral trauma is 47.5% ureteroureterostomy and 25% ureteroneocystostomy. Conclusion: Most cases of ureteral trauma are experienced by women, and most commonly due to iatrogenic trauma. Iatrogenic ureteral trauma caused by gynecology procedure is the most common.
COMPARISON OF PERCUTANEOUS NEPHROLITOTOMY (PCNL) IN PRONE AND SUPINE POSITION: A SINGLE CENTRE EXPERIENCE REPORT Safriadi, Ferry; Ramdhan, Dadan
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.643

Abstract

Objective: This study aims to compare outcomes of supine percutaneous nephrolithotomy to prone percutaneous nephrolithotomy as a traditional approach in Hasan Sadikin Hospital Bandung. Material & Methods: Data was taken from urology’s database between 2003-2012, which contain data of prone position (2003-2007), and supine position (2008-2012). Three hundred forty-nine patients were included in this study. We reviewed data on demography, stone burden, operating time, stone-free rate, transfusion rate, hospital stay, and major complications. Results: Of 174 patients underwent prone position, and 175 patients were part of the supine position. Age means of prone position was 51.0 years old, the supine position was 50.5 years old. The number of male patients was 65.5% for prone, and 66.1% for supine. The mean stone's largest diameter of prone was 23.87 mm, supine was 22.36 mm. The operating time of prone was 107 minutes; supine was 90 minutes. The stone-free rate of prone was 94.7%; supine was 91.3%. The mean hospital stays of prone was 14.3 days; supine was 9.6 days. The transfusion rate of prone position was 8.9%, supine was 7.2%. No major complications were recorded. Conclusion: Higher stone-free rates are achieved with patients in the prone position during PCNL. Supine position has shorter operating time, and hospital stay, lower blood transfusion rates. The complication rate is not different between the two positions.
FACTORS INFLUENCING THE DEGREE OF ERECTILE DYSFUNCTION IN BICYCLE RACE ATHLETES Tampubolon, Daniel Taruna; Wibisono, Dimas Sindhu; Muttaqin, Zainal; Julianti, Hari Peni
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.648

Abstract

Objective: This research aims to identify factors influencing the degree of erectile dysfunction in bicycle racing athletes. Material & Methods: This study used quantitative analysis and cross-sectional research design. Samples included in this research were 54 respondents in accordance to the inclusion and exclusion criteria of this study, and were willing to participate in this research. The data were collected using the IIEF-5 (International Index of Erectile Function-5) questionnaire. The data were then edited, coded and analyzed using Chi-square (bivariate analysis). Results: The results showed correlations between the degree of erectile dysfunction in bicycle race athletes and age (PR= 1.182; 95%CI= 0.403-3.465; p= 0.976), cycling history (PR= 0.462; 95% CI= 0.490-4363; p= 0.687), cycling frequency (PR=1.400; 95% CI= 0.299-6.560; p= 0.72), cycling duration (PR= 0.333; 95% CI= 0.074-1.507; p= 0.165), furthest cycling distance (PR= 0.883; 95% CI= 0.267-2.919; p= 1.00), and type of saddle (PR= 0.271; 95% CI= 0.481-1.547; p= 0.221) respectively. Conclusion: There were no significant correlation (p= >0.05) in all variables analyzed in this study.
THE EFFECT OF CONDITIONED-MEDIUM HUMAN ADIPOSE-DERIVED MESENCHYMAL STEM CELL IN APOPTOSIS OF BLADDER CANCER CELLS Mawdudi, Ari Alauddin; Hidayatullah, Furqan; Bachtiar, Indra; Rachman, Arif; Putri, Indri Lakhsmi; Castiglione, Fabio; Djatisoesanto, Wahjoe; Hakim, Lukman
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.653

Abstract

Objective: To determine the effect of conditioned medium human Adipose-Derived Mesenchymal Stem Cells (CM-hADMSC) on apoptosis of urothelial bladder cancer cells. Material & Methods: Bladder (5637) cancer cell lines cultured in conditioned media harvested from human adipose-derived mesenchymal stem cells (hADMSC). Flow cytometry tests were carried out using the Flowcytometry Acquisition cell sorting (FACS) Calibur to measure apoptosis. Results: There was a significant difference in the percentage of late apoptosis in the group receiving culture medium treatment: CM-hADMSC 1: 1 to the entire study group. Further analysis revealed no difference in the average percentage of late apoptosis in groups exposed to culture medium: CM-hADMSC 1: 2 and culture medium: CM-hADMSC 1: 4 (p> 0.05). Conclusion: CM-hADMSC at a 1: 1 dose concentration to culture medium obtain a significant increase of apoptosis in bladder cancer cells.
THE EFFECT OF CONDITIONED MEDIUM ADIPOSE DERIVED MESENCHYMAL STEM CELLS IN UROTHELIAL CARCINOMA CULTURE CELLS VIABILITY Prasetyo, Suryo; Hidayatullah, Furqan; Bachtiar, Indra; Rachman, Arif; Putri, Indri Lakhsmi; Castiglione, Fabio; Soebadi, Doddy M.; Hakim, Lukman
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.654

Abstract

Objective: This study aimed to gives a perspective in CM-ADMSCs effect in urothelial bladder cancer viability. Material & Methods: Human bladder cell carcinoma type 5637 was used as the subject of this in vitro study. This study contains four different groups: untreated control group, Culture medium: hADMSCs with 1:1, 1:2, and 1:4 concentration group. Each group consists of 6 replications to prevent bias of the study. Viability was determined with MTT assay methods and evaluation performed after 48 h exposure of conditioned medium. Results: A post hoc test was conducted to analyze the data. The 5637 bladder cancer cell line demonstrated significantly decreased viability after exposure to culture medium: CM-hADMSCs 1:1 (p: 0.002) compared to the negative control group, but there are no significant differences in viability between the control groups with groups that were exposed to culture medium: CM-hADMSCs 1:2 and culture medium: CM-hADMSCs 1:4 with p: 0.480 and p: 0.060 respectively. Conclusion: Decreased viability of urothelial bladder cancer cells after exposure to CM-hADMSCs occurs at a concentration of 1:1 and Dosage addition more than 1:1 concentration doesn’t give any advantages.
HYPERTENSION EFFECTS ON THE DECREASED KIDNEY FUNCTION PROGRESIVITY IN BENIGN PROSTATIC HYPERPLASIA PATIENTS Dhiemas Trisyuananda Eniestama; Aziz, Ayu Munawaroh; Wahyudi, Septa Surya
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.660

Abstract

Objective: A comprehensive knowledge about BPH and hypertension is needed to reduce morbidity and mortality in patients with decreased kidney function due to the two diseases. Material & Methods: This research used the observational analytics method with cross-sectional design. This research used secondary data from medical records of BPH patients in Bina Sehat Hospital and Paru Hospital from January 1st to December 1st 2019. Results: Comparative serum creatinine test results in hypertensive BPH patients with non-hypertensive BPH patients using the Mann Whitney test, obtained p= 0.000. Based on these results it can be concluded that there are significant differences in serum creatinine between hypertensive BPH patients and non-hypertensive BPH patients. Correlation test results using the Spearman test between serum creatinine with blood pressure systole and diastole all samples obtained each p= 0.000 r= 0.399 for systolic blood pressure and p= 0.000 r= 0.337 for diastole blood pressure. Based on these results it can be concluded that there is a significant correlation between serum creatinine with systolic and diastolic blood pressure of the patient. Conclusion: Hypertension will worsen the kidney function decline in BPH patients seen from an increase in serum creatinine.
The LOWER URINARY TRACT SYMPTOMS IN ANURIA AND NON-ANURIA PATIENTS AFTER RENAL TRANSPLANTATION: A COMPARATIVE STUDY Rahmita, Maulidina Medika; Harrina Erlianti Rahardjo; Arry Rodjani; Nur Rasyid
Indonesian Journal of Urology Vol 28 No 2 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i2.661

Abstract

Objective: The purpose of this study is to examine the difference of lower urinary tract (LUT) symptoms in anuric and non-anuric individuals after renal transplantation (RT). Material & Methods: LUT function and symptoms were assessed in subjects who had undergone RT at Cipto Mangunkusumo General Hospital, Jakarta, from November 2016 to June 2017. Subjects were divided into anuric and non-anuric groups. We excluded patients with surgical complications that could not undergo uroflowmetry. Results: Thirty-two (21 male, 11 female) subjects were recruited in this study. The anuric subjects were younger than the non-anuric ones (47 ± 12.82 vs. 51.31 ± 16.33, p < 0.001) There were no significant differences in the International Prostate Symptoms Score (IPSS) (6.5 ± 3.67 vs. 6.25 ± 2.95, p = 0.567), Overactive Bladder Symptoms Score (OABSS) (4.06 ± 2.01 vs 4.12 ± 2.39, p = 1.000), maximum urinary flow rate (Qmax) (20.32 ± 9.04 vs. 22.32 ± 10.31, p = 0.956), post-void residual (PVR) (41.12 ± 37.63 vs. 47.62 ± 38.63, p = 0.361) and voided volume (227.88 ± 112.30 vs 251.06 ± 126.75, p = 0.588) between anuric and non-anuric subjects, respectively. IPSS-voiding symptom, IPSS-storage symptom, and OAB symptom did not differ significantly between both groups (p > 0.05). Thirteen (13/16) and seven (7/16) subjects of the anuric and non-anuric groups were both pleased with their quality of life, respectively. Conclusion: LUT symptoms do not differ between anuric and non-anuric patients.
CATALASE 1 GENE EXPRESSION (CAT-1) IN HYPERGLICEMIA INDUCED TESTIS, AS AN ANTIOXIDANT THERAPY INDICATORS Zulfan, Ahmad; Wonatorey, Nickanor K. R
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.664

Abstract

Objective: This study aims to analyze the effects of hyperglycemia status on the function of testicular spermatology, especially CAT-1. Material & Methods: This study was an experimental pre-clinical study. Twenty-seven rats were divided into 3 groups: normal, 2 weeks, and 4 weeks hyperglycemia. The hyperglycemic state in the Wistar rats was induced by Streptozotocin (STZ). All data were collected and analyzed with SPSS 20.0. At two and four weeks, testicular tissue was extracted and it will be processed using the Total RNA Mini Kit FavorPrepTM then quantitative PCR was performed using the SYBR® Fast qPCR Kit. Results: CAT-1 gene expression in the hyperglycemia induction group increased when induced for 2 weeks and again after 4 weeks compared to controls (18.88 ± 4.7 and 21.45 ± 5.52 vs 10.83 ± 3.4). However only induction after 2 weeks was statistically significant (p= 0.021). Conclusion: CAT-1 (Catalase) gene expression has increased in testicular tissue under conditions of hyperglycemia.
COMPARISON OF KETOROLAC VERSUS DICLOFENAC AS TREATMENT FOR ACUTE RENAL COLIC: A SYSTEMATIC REVIEW AND A NETWORK META-ANALYSIS (DIRECT AND INDIRECT COMPARISON) Arianto, Eko; Rodjani, Arry; Wahyudi, Irfan
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.667

Abstract

Objective: The purpose of this study is to compare which analgesic is better between ketorolac and diclofenac. Material & Methods: A systematic search was conducted in Pubmed, Science Direct, Cochrane, EBSCO, Proquest database, and PICO analysis was used in determining the study question. The included article in the analysis was randomized controlled trials. Results: A total of 6 articles were included in the analysis, with no significant differences between ketorolac and diclofenac both in a direct comparison and indirect comparison (OR 2.74 [95%CI 0.72 – 10.43]; p= 0.14 and OR 0.51 [95%CI 0.29 – 0.91]; p= 0.49). Conclusion: Both ketorolac and diclofenac have the same efficacy in treating renal colic.
RELATION OF TOTAL CHOLESTEROL TO PROSTATE VOLUME AND INTRAVESICAL PROSTATIC PROTRUSION IN BENIGN PROSTATIC HYPERPLASIA PATIENTS Made Devi Desyana Arisandi; Wahyudi, Septa Surya; Fatmawati, Heni
Indonesian Journal of Urology Vol 28 No 2 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i2.675

Abstract

Objective: To determine the relationship between total cholesterol, prostate volume, and intravesical prostatic protrusion in patients with benign prostatic hyperplasia. Material & Methods: This study used a cross-sectional method, carried out at the Paru and Bina Sehat Hospital in Jember. The sample in this study was BPH patients who met the inclusion criteria taken through medical record data from October 2019 to January 2020 Results: Samples on this study amounted to 33 patients. In this study, there was a difference between normal and high cholesterol with prostate volume in BPH patients (p = 0.00) and there was a significant relationship between cholesterol and prostate volume with strong correlation strength (p = 0.00 and r = 0.751) while the difference between high and normal cholesterol with IPP obtained insignificant results (p = 0.211) and the correlation between cholesterol and IPP obtained an insignificant relation with weak correlation strength (p = 0.217 and r = 0.221). Conclusion: There is a significant relationship between total cholesterol and prostate volume and a significant difference in prostate volume between normal and high total cholesterol in BPH patients, while there is no significant result between total cholesterol and intravesical prostatic protrusion in BPH patients.

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