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INDONESIA
Biomedika
Published by Universitas Muhammadiyah Surakarta
ISSN : -     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
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Articles 399 Documents
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HUBUNGAN TINGKAT PENGETAHUAN TENTANG PEMERIKSAAN PAYUDARA SENDIRI (SADARI) DENGAN PERILAKU SADARI PADA MAHASISWI NON KESEHATAN DI UNIVERSITAS MUHAMMADIYAH YOGYAKARTA Baswedan, Rizki Hafidzah; Listiowati, Ekorini
Biomedika Vol 6, No 1 (2014): Biomedika Februari 2014
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Breast cancer is a type of malignant tumor that most commonly affects women around the world, both in the developed and developing countries, as evidenced by the discovery of 1:38 million new cases and 458 400 deaths from breast cancer in 2008. In Indonesia, breast cancer is now the number one killer and every year there are an estimated 100 new cases per 100,000 population in Indonesia. This can be prevented by spreading knowledge about cancer and early detection by performing routine breast self-examination. The American Cancer Society recommends breast self-examination performed on women aged 20 years. Students of non-health is one component of society that have a high level of knowledge, but less exposure to health problems.This study uses observational analytic with cross sectional approach. The subjects of this study were non-health students from Islamic faculty, agriculture faculty, and engineering faculty. The number of samples in this study was 209 respondents. The level of knowledge about breast tumor, BSE, and BSE behavior was assessed using a questionnaire followed by interview. The results obtained were processed using a computerized system with the Spearman correlation test.The results showed that there is a relationship between the level of knowledge about BSE and BSE behavior in non-health student although statistical tests showed no signifi cant correlation p 0.680 (p> 0.05). The relationship between the level of knowledge about BSE and BSE behavior on non-health student infl uenced by various factors including experience, education, resources, and bridged by a positive attitude.Keywords: Knowledge Level, Behaviour, Breast Self-Examination (BSE), Non-health Students
HUBUNGAN PENGETAHUAN TENTANG HIPERTENSI DENGAN PENGENDALIAN TEKANAN DARAH PADA PASIEN HIPERTENSI DI POLIKLINIK PENYAKIT DALAM RSUD DR.MOEWARDI SURAKARTA Wulansari, Jayanti; Ichsan, Burhannudin; Usdiana, Devi
Biomedika Vol 5, No 1 (2013): Biomedika Februari 2013
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Nowadays, hypertension becomes the main problem in the world. Uncontrolled hypertension remains the main health problem. One of the problems that cause uncontrolled blood pressure is the less knowledge of hypertension. Patient’s knowledge and awareness in hypertension is the important factor to control the blood pressure. The aim of this study is to know the relation between hypertension knowledge and blood pressure restraint to hypertension patient in the Internist Polyclinic RSUD dr.Moewardi Surakarta. This research used analytic survey method in cross sectional approach. It took 57 sample of hypertension patient. It used purposive sampling technique. This research used Chi Square statistic test. In forty two patients (73,7%) with well-knowledge, 31 patients hypertension (73,8%) have controlled-blood pressure and uncontrolled blood pressure is 11 patients (26,2%). Whereas, in 15 patients (26,3%) who has lack-knowledge found controlled-blood pressure in 6 patients (40%), and uncontrolled blood pressure in 9 patients (60%). There was not found less-knowledge patients. The Chi Square test found signifi cance probability (p)= 0,019. There is relation between hypertension knowledge and controlling blood pressure.Keywords: knowledge, hypertension, controlling blood pressure
PENGHAMBATAN KSANTIN OKSIDASE OLEH KOMBINASI EKSTRAK TEMPUYUNG (Sonchus Arvensis) DAN SALAM (Syzygium Polyanthum) PADA MENCIT HIPERURISEMIA ., Dr. Muhtadi; Retnani, Idi; Wahyuningtyas, Nurcahyanti
Biomedika Vol 4, No 1 (2012): Biomedika Februari 2012
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Tempuyung (Sonchus arvensis) and salam (Syzygium polyanthum) leaves can lower uric acid levels were studied. The purpose of this research was to determine mechanism of combined o f tempuyung and salam extracts to reduce uric acid levels by inhibiting xanthine oxidase in hyperuricemic mice. This research used completely randomized design using mice. Fifteen mice were made hiperuricemic by 250 mg/kgBW potassium oxonate p.o then the mice were divided into 3 groups. Group I induced 10 mg/kgBW allopurinol p.o as positive control, group II induced tempuyung-salam p.o each 100 mg/kgBW as the treatment group, group th III induced 0.5 mL/20 gBW distilled water p.o as negative control. Liver was taken 4 day after 2 hours induced potassium oxonate. Data inhibition xanthine oxidase activity was tested with Mann-Whitney. The result showed that the combination of tempuyung-salam extract each 100 mg/kgBW could inhibit xanthine oxidase activity of 51,16%±2,76%, while allopurinol 90,20%±0,16% (p = 0.000).Keyword: Hyperuricemia, Xanthine Oxidase, Sonchus arvensis, Syzygium polyanthum
JUVENILE DERMATOMIYOSITIS: PENEGAKAN DIAGNOSIS Prakoeswa, Flora Ramona Sigit; Suswardana, .; Danarti, Retno
Biomedika Vol 6, No 1 (2014): Biomedika Februari 2014
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Juvenile dermatomiyositis (JDM) merupakan suatu penyakit autoimun infl amatif yang jarang dijumpai dan secara khas ditandai oleh adanya lesi-lesi kulit tipikal serta kelemahan otot proksimal yang simetris. Etiologi penyakit tersebut belum diketahui dengan pasti, namun demikian patogenesisnya diketahui bersifat multifaktorial meliputi faktor genetik, paparan sinar ultra violet (UV) serta infeksi oleh berbagai mikroba seperti virus Coxsackie atau Borrelia burgdorferi. Penegakan diagnosis JDM adalah berdasarkan kriteria Bohan-Peter meliputi: 1) kelemahan otot proksimal simetris, 2) peningkatan enzim otot, 3) infl amasi miopati pada hasil biopsi otot 4) gambaran miyopati pada hasil pemeriksaan EMG, dan 5) lesi kulit tipikal. Ditemukannya papul-papul Gottron dan heliotrope rash di kulit, serta adanya kelemahan otot proksimal yang simetris, merupakan manifestasi klinis yang khas untuk JDM. Terapi lini pertama penatalaksanaan JDM adalah kortikosteroid sistemik. Dilaporkan satu kasus JDM pada seorang anak perempuan berusia 6 tahun. Diagnosis ditegakkan berdasarkan adanya lesi kulit tipikal, kelemahan otot proksimal simetris dan peningkatan kadar enzim penanda infl amasi jaringan muskuloskeletal. Pasien berespon baik terhadap pemberian kortikosteroid adekuat serta tabir surya.Kata Kunci: Juvenile dermatomiyositis, systemic corticosteroid
HUBUNGAN ANTARA PERSEPSI PASIEN TENTANG KUALITAS DAN KEMAUAN MEMBAYAR PELAYANAN KESEHATAN GIGI DI MMC UMS Karyadi, Edi
Biomedika Vol 3, No 2 (2011): Biomedika Agustus 2011
Publisher : Universitas Muhamadiyah Surakarta

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Until now there is no standard for measuring the standard willingnesss to pay of patients and patient satisfaction for the quality of dental care. Research purposes to assess the magnitude of willingness to pay for outpatient dental care and want to test the factors that affect willingness to pay for outpatient dental care at the Muhammadiyah Medical Center (MMC UMS). This study was observational analytic study with cross-sectional approach, where all the variables studied were observed at the same time. The study population was patients who received outpatient dental care with simple random sampling. To the adequacy of the sample required a minimum sample size of 120. The data collection by questionnaire content validity technique. The results showed 60.8% of patient education level is college. The average patient’s willingness to pay for dental care Rp.60.833. The average satisfaction score of patients on dental health servicesis 77.35 (including the high satisfaction category). While the average patient income for Rp.2.110.417. Statistical analysis proves’ there is a positive correlation’ between service quality and willingness to pay for dental care patients (r=0247, p <0.05). In this study also proves’ there is a positive correlation’ between the patient and the willingness to pay in comedental care (r=0.730, p <0.05). With the regression test showed the ‘threev ariables (education, income and quality of service)’ jointly able to predict variations in the willingness of patients to pay for 59.7% and statistically  t regression model (valid) (p <0.001).Keywords: education, income, quality of service, willingnestopay
EFEK GEL EKSTRAK HERBA PEGAGAN (Centella asiatica L. Urban) DENGAN GELLING AGENT HIDROKSIPROPIL METHYLCELLULOSE TERHADAP PENYEMBUHAN LUKA BAKAR PADA KULIT PUNGGUNG KELINCI Sujono, Tanti Azizah; Hidayah, Ullya Nur Wahyu; Sulaiman, T.N. Saifullah
Biomedika Vol 6, No 2 (2014): Biomedika Agustus 2014
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Pegagan (Centella asiatica L. Urban) contain saponin asiaticoside, which is a structural protein. The compound plays a role in the wound healing process by the formation of collagen. This research was conducted to determine the effect of wound healing of burns on New Zealand male rabbits using gel extract of Pegagan (Centella asiatica L. Urban) herbs using hydroxypropyl methylcellulose (HPMC) as gelling agent. This research was an experimental with the same subject design, using � ve male New Zealand rabbits to test the wound healing of burns, and the backs of each rabbit were divided into six treatment i.e : positive control (Bioplasenton), negative control (no treatment), control HPMC base (no extract), and three formula with herbal extracts of Centella asiatica with a concentration of gelling agent HPMC 8%, 9%, and 10% respectively. Gel was applied to the back of rabbits with the use ± 0.3 grams once daily until the wound diameter equal to zero or until healed. The data was analyzed by one way anava with a 95% confidence level. The result showed that of the gelling agent HPMC concentration effect on the increased the viscosity, and decreased the spreadability and the burn wound healing time is a longer. Gel herb pegagan extract (Centella asiatica L. Urban) with a gelling agent HPMC concentration of 8% (17,60±1,14 days) most effectively heal burns compared to the concentration of 9% (19,40 ±1,14 days) and concentration 10% (20,40±1,14 days).Keywords: Centella asiatica L. Urban, gel, hydroxypropyl methylcellulose, burns.
HUBUNGAN DIABETES MELITUS DENGAN KEJADIAN STROKE ISKEMIK DI RSUD DR. MOEWARDI SURAKARTA TAHUN 2010 Ramadany, Aulya Farra; Pujarini, Listyo Asist; Candrasari, Anika
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

From survey at Dr. Moewardi Hospital in the year 2010, the incidence of stroke patients increase 5-7% every year. Diabetes mellitus has a relationship with ischemic stroke through aterosklerosis. However, the relationship of diabetes mellitus as a risk of ischemic stroke remains uncertain due to diabetes is not a single factor for stroke. Research aim was to determine the relationship between the incidence of diabetes mellitus and ischemic stroke. It was conducted at the neurologi unit in Dr.Moewardi Hospital Surakarta, the design was a cross sectional with sample size of 132 people. The sampling technique used simple random sampling. The result is the number of ischemic stroke patients with diabetes mellitus by 47 people (71.21%). From chi square analysis (x 2) x 2 = 13.516 obtained and p <0.000 with a value of OR = 3.8 and IK = 1.841 to 7.869. Its mean that there was a relationship between diabetes mellitus and incident ischemic stroke and people with diabetes mellitus have a risk 3,8 more times will got stroke ischemic than people without diabetes mellitus.Keywords: diabetes mellitus, ischemic, stroke
PERBEDAAN FREKUENSI DIARE ANTARA BAYI YANG DIBERI ASI EKSKLUSIF DENGAN BAYI YANG DIBERI SUSU FORMULA PADA RENTANG USIA 2- 4 BULAN DI WILAYAH KERJA PUSKESMAS KLATEN TENGAH Rahmitasari, Putri; Ichsan, Burhannudin; Ermawati, Sahilah
Biomedika Vol 4, No 2 (2012): Biomedika Agustus 2012
Publisher : Universitas Muhamadiyah Surakarta

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The main indicator of public health’s degree is infant mortility rate (IMR). One of the main things that cause infant mortility is diarrhea. The existence of diarrhea’s incidence in infants can be caused due to errors in the form of food other than breast milk feeding at the age of 4 months or the practise of infant feeding with formula milk (replacement feeding). This research was an observational analytic research with cross sectional approach. Samples obtained amounted to 80 respondents who are infants aged 2-4 months in various “posyandu” in the area of Central Klaten. This sample had fulfiilled the predetermined criteria. The research instrument used a questionnaire. for the result, there were 21 respondents of 80 respondents obtained who had diarrhea. Respondents of exclusive breastfeeding who had frequency of diarrhea is rarely as many as 5 babies, whereas 1 baby for often category. Respondents of infant formula who had frequency of diarrhea is rarely as many as 12 babies, whereas 3 babies for often category. There were significant differences between infants who were breastfed exclusively with formula-fed infants againts diarrhea frequency indicated by the value of p = 0,032.Keywords: Frequency of Diarrhea, Exclusive Breast Feeding, Formula Feeding Infant, Infants Aged 2-4 Months
HUBUNGAN TINGKAT PENGETAHUAN HAND HYGIENE DENGAN KEPATUHAN PELAKSANAAN HAND HYGIENE PADA PESERTA PROGRAM PENDIDIKAN PROFESI DOKTER Widyanita, Anietya; Listiowati, Ekorini
Biomedika Vol 6, No 1 (2014): Biomedika Februari 2014
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Prevention and Control Program (PPI) including hospital accreditation assessment. One of the standard phase is hand hygiene. The hands of health care are often contact with the patient and his environment, thus becoming the most common transmission of HAIs. Hand hygiene can reduce HAIs if done with appropriate recommendation. This study was conducted to determine the relationship between the level of knowledge of hand hygiene and hand hygiene compliance implementation. This study was observational analytic with cross sectional approach. Subjects were participants of educational programs in the medical profession with a total sampling technique. Instrument research using questionnaires and observation sheet. Analyzed with descriptive statistics, the average level of knowledge and implementation of hand hygiene compliance in respondents is less. Analysis distribution of respondents by sex, male totaled 17 people and female totaled 14 people, distribution of respondents according to the level of knowledge, less value totaled 29 people (93.5%) and enough value totaled 2 people (6.5%), distribution of respondents according to the level of compliance, less value totaled 26 people (83.9%) and good value totaled 5 people (16.1%). Analysis using a correlation test, 0.599 correlation value, where p<0.005, positively related. This study shows that there is a positive relationship between the level of knowledge of hand hygiene and hand hygiene compliance implementation. The average level of knowledge has less value. The average rate of hand hygiene compliance implementation has less value.Keywords: Knowledge level of hand hygiene-Implementation of hand hygiene compliance
IMUNITAS ALAMIAH: EOSINOPHIL EXTRACELLULAR TRAPS (EET) Jatmiko, Safari Wahyu
Biomedika Vol 5, No 1 (2013): Biomedika Februari 2013
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Eosinophils play a role in the defense against viruses, bacteria, fungi and parasites, as well as be involved in the pathogenesis of allergic and autoimmune diseases. The role of eosinophils in the defense against bacterial run by enzymes found in the granules such as MBP, ECP, EPO, and EDN, and spending EET. EET formation is determined by the presence of free radicals and intracellular calcium. The antimicrobial function of EET played by Histon.Keywords: eosinophil , Eosinophils extracellular traps

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