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INDONESIA
JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health)
Published by Universitas Airlangga
ISSN : 18297285     EISSN : 2540881X     DOI : -
Core Subject : Health,
Jurnal Kesehatan Lingkungan with registered number ISSN 1829-7285 (printed) and ISSN 2540-881x (online) is a scientific open access journal published by Environmental Health Department of Public Health Faculty, Universitas Airlangga, Indonesia. Our journal aims to become a media of research results dissemination and exchange of scientific work of various groups, academics, practitioners and government agencies. Since 2018, this journal in one year will be published four times in January, April, July, and October.
Arjuna Subject : -
Articles 402 Documents
Attenuation Effects of Time-Restricted Feeding Initiated Prior to and During Benzene Exposure on Leukocyte Profiles in Rats: A Preliminary Study Reny Indrayani; Lilis Sulistyorini; Hari Basuki Notobroto; I Ketut Sudiana
JURNAL KESEHATAN LINGKUNGAN Vol. 18 No. 4 (2026): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v18i4.2026.355-365

Abstract

Introduction: Benzene exposure is a major cause of hematotoxicity, which can trigger leukopenia and immunosuppression through oxidative stress. This study aimed to analyze and compare the attenuation effect of Time-Restricted Feeding (TRF) with different durations (12 and 8-hours) initiated prior to and during benzene exposure on the total white blood cell (TWBC) count and differential WBC count profile in Wistar rat. Methods: This was a purely experimental study, involving 28 rats which were divided randomly into 4 groups (KN fed ad libitum without benzene exposure; K0 fed ad libitum and exposed to 300 ppm benzene; X1 12-hour TRF and exposed to 300 ppm benzene; X2 8-hour TRF and exposed to 300 ppm benzene). TWBC and differential WBC count profiles were calculated using an automated hematology analyzer. Results and Discussion: Exposure to 300 ppm benzene vapor in K0 significantly decreased TWBC and absolute lymphocyte counts compared to KN. TWBC in groups X1 and X2 were within the normal range and significantly higher than in K0. Group X2 showed a significant increase in absolute neutrophil counts compared to K0, which is suspected to be an indication of starvation stress due to the longer fasting window. Conclusions: 12 or 8-hour TRF initiated prior to and during benzene exposure, successfully attenuated the decrease in TWBC and lymphocyte counts caused by benzene exposure. There were no significant differences in all WBC parameters between 12 and 8-hour TRF. Further research with oxidative stress biomarker measurements is needed to validate the cellular mechanism of TRF's attenuating effect.
Spatial Association Between Dengue Incidence and Larvae-Free Index: A Bivariate Spatial Autocorrelation Analysis in Surabaya, Indonesia Khuliyah Candraning Diyanah; Ririh Yudhastuti; Lilis Sulistyorini; Hari Basuki Notobroto; Zida Husnina; Muhammad Rasyid Ridha; Babucarr Jassey; Aditya Sukma Pawitra; Diva Alishya Shafwah; Rahmat Dapari; Nafi'atul Irbah; Wira Satya Nugraha Wicaksono
JURNAL KESEHATAN LINGKUNGAN Vol. 18 No. 4 (2026): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v18i4.2026.366-379

Abstract

Introduction: Dengue transmission in Surabaya, Indonesia, varies across urban villages, but its spatial relationship with vector-control performance remains insufficiently understood. This study examined dengue incidence, the Larvae-Free Index (LFI), and their bivariate spatial association. Methods: This spatial ecological study analysed annual confirmed dengue cases and LFI data from all 154 urban villages in Surabaya during 2020–2025, obtained from the Surabaya City Health Office. Incidence was calculated per 10,000 population. Multiplicative seasonal decomposition characterised monthly case patterns. Global Moran’s I and Local Indicators of Spatial Association (LISA) assessed spatial clustering, while Bivariate Moran’s I and Bivariate LISA (BiLISA) examined associations between local dengue incidence and neighbouring LFI values. Results and Discussion: Dengue incidence clustered significantly in five of six years (I = 0.0784–0.2727), except 2024 (I = 0.0280; p = 0.222). LFI clustered significantly every year (I = 0.2190–0.3087; p = 0.001). Bivariate Moran’s I was negative in five years and significant in 2020 (−0.0805; p = 0.022), 2021 (−0.0875; p = 0.019), and 2025 (−0.1046; p = 0.003), indicating spatial associations between higher incidence and lower neighbouring LFI. In 2025, LISA identified 10 High–High and 15 Low–Low dengue clusters. BiLISA identified High–Low villages annually, with Ujung and Pegirian recurring most frequently. Conclusion: Dengue incidence and LFI exhibited spatial clustering, with significant inverse spatial associations in three years. LFI should complement, rather than replace, dengue surveillance when identifying priority areas for targeted vector control.

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