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INDONESIA
Acta Pharmaceutica Indonesia
ISSN : 0216616X     EISSN : 27760219     DOI : -
Core Subject :
Acta Pharmaceutica Indonesia merupakan jurnal resmi yang dipublikasikan oleh Sekolah Farmasi Institut Teknologi Bandung. Jurnal ini mencakup seluruh aspek ilmu farmasi sebagai berikut (namun tidak terbatas pada): farmasetika, kimia farmasi, biologi farmasi, bioteknologi farmasi, serta farmakologi dan farmasi klinik. Acta Pharmaceutica Indonesia is the official journal published by School of Pharmacy Institut Teknologi Bandung. The journal covers all aspects of pharmaceutical issues which includes these following topics (but not limited to): pharmaceutics, pharmaceutical chemistry, biological pharmacy, pharmaceutical biotechnology, pharmacology and clinical pharmacy.
Arjuna Subject : -
Articles 254 Documents
EVALUASI PENYIMPANAN OBAT HIGH ALERT DI GUDANG DAN APOTEK RAWAT INAP DI INSTALASI FARMASI RUMAH SAKIT JIWA DAERAH PROVINSI JAMBI Luthfiyyah, Annisa; Yudha Putra, Diky Okta; Sani K, Fathnur
Acta Pharmaceutica Indonesia Vol. 50 No. 1 (2025)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/api.v50i1.24976

Abstract

The storage of high alert medications at the Regional Mental Hospital (RSJD) of Jambi Province is a crucial aspect of healthcare that impacts patient safety. This study aims to evaluate the compliance of high alert medication storage in the warehouse and inpatient pharmacy of RSJD Jambi Province based on the applicable Standard Operating Procedures (SOP). The research was based on observation with a qualitative descriptive approach, where data is collected through a checklist containing indicators of storage compliance. The results show that all storage procedures for high alert medications have been implemented effectively, with a compliance percentage of 100%. The medications are stored separately from other drugs, in accordance with FIFO and FEFO principles, and are clearly labeled. The conclusion of this study emphasizes that the management of high alert medications at RSJD Jambi Province has met the established standards, thereby minimizing the risk of errors in medication handling.
FORMULASI DAN EVALUASI GRANUL EFERVESEN EKSTRAK DAUN SALAM (SYZYGIUM POLYANTHUM (WIGH) WALPERS) Akbar, Nanda Dwi Akbar; Rizky Uswatun Arifah, Anisya; Setyaningsih, Wahyu; Putri Pitarisa Sudarsono, Agustina
Acta Pharmaceutica Indonesia Vol. 50 No. 1 (2025)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/api.v50i1.25032

Abstract

Bay leaves (Syzygium polyanthum (Wigh) Walpers) contain flavonoid compounds which act asantioxidants for the treatment of diabetes mellitus. The ethanol extract of bay leaves can reduceblood glucose levels in white rats that have been induced by streptozotocin. Effervescentgranules dissolve easily in water and provide a fresh taste like fizzy drinks making it easier toconsume, especially for consumers who cannot take capsules or tablets. The aim of this researchwas to formulate and evaluate bay leaf extract effervescent granules. The research stage wasbegun by producing bay leaf extract by maceration. The effervescent granule formulation wasmade in 3 formula that contain 1% bay leaf extract, citric acid, tartaric acid, sodium bicarbonate,aspartame, magnesium stearate, talc, lactose and PVP K-30 concentrations of 2% (F1), 4% (F2),and 5% (F3). Effervescent granules were prepared by dry granulation. The physical propertiesof bay leaf extract effervescent granules that were observed included organoleptic, watercontent, flow time, angle of repose and effervescent cessation time. The results showed that F1had the greatest water content (2.485%), flow time (10.274) and angle of repose (24.70), but F3had the greatest effervescent cessation time (4.1 minutes) compared to F1 (3, 3 minutes) and F2(3.5 minutes). This research can be concluded that effervescent granules containing 1% bay leafextract and PVP K-30 with varying concentrations of 2, 4 and 5% meet the requirements forwater content, flow time, angle of repose and effervescent cessation time.
STUDI EFEK SAMPING ANTITUBERKULOSIS PADA PASIEN RAWAT JALAN DI SALAH SATU RUMAH SAKIT DI GARUT Fadhilla, Genialita; Fatimah P.H, Sitti; Rahma, Asilia
Acta Pharmaceutica Indonesia Vol. 50 No. 1 (2025)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/api.v50i1.25067

Abstract

Tuberculosis remains a global health problem with high incidence and mortality rates, 724,309 people infected with tuberculosis. One of the challenges in the treatment of tuberculosis is side effects of antituberculosis (OAT) which can lead to treatment discontinuation and drug resistance. This study aimed to identify the incidence of OAT side effects in outpatient tuberculosis patients at DOTS clinic in one of  hospitals at Garut. This study used a descriptive survey design with a cross-sectional. Data were collected from 31 tuberculosis patients who met the inclusion criteria through interviews and medical records review during May-June 2024. Respondents used fixed dose combination (FDC) therapy (94% ) and  single drug formulation(6%). OAT side effects are divided into mild and severe effects. The mild side effects most often experienced by respondents were redish urine (94%), flu-like symptoms (81%), and joint pain (77%). Meanwhile, the most common severe side effect experienced by respondents was visual (23%). Side effects are managed by administering symptomatic drugs such as antiemetics, analgesics, antipyretics, and vitamin B6. Intensive monitoring and appropriate management of side effects are essential to improve treatment adherence, prevent drug resistance, and reduce morbidity and mortality from tuberculosis.  
Front Matter: Acta Vol 50 (1) Indonesia, Acta Pharmaceutica
Acta Pharmaceutica Indonesia Vol. 50 No. 1 (2025)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/api.v50i1.26023

Abstract