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Published by Universitas Lambung Mangkurat

ISSN : 14120550 EISSN : 25485660 DOI : http://dx.doi.org/10.20527

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 478 Documents

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DESCRIPTION OF EFFECTIVENESS OF CILOSTAZOL AND ASPIRIN AS ADJUVANT OF DIABETIC FOOT WAGNER GRADE II AND III Pandji Winata Nurikhwan; Zairin Noor; Nelly Al Audhah
Berkala Kedokteran Vol 10, No 2 (2014)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Inflammation in patients with diabetic foot will activate platelets and cause aggregation and lead to stasis of blood flow. This inflammation is caused by infection of the diabetic foot. Management of diabetic foot infections in patients is the use of antibiotics. However, the presence of vascularization disorders causing antibiotic delivery to the site of infection to be disrupted so that the process of eradication of infection would be inhibited. One of inflamation markers on patient with diabetic foot is increasing of ESRs.The general objective of this study was to determine the efficacy difference between cilostazol and aspirin as an adjuvant to accelerate tissue healing of diabetic foot care Wagner Grade II – III based on erythrocyte sedimentation rate. This study is a descriptive study using the double-blind and randomized pretest-posttest design. A total of 14 samples is obtained by consecutive sampling. The results showed that four patients given cilostazol showed a 35% reduction in ESR and ten patients were given aspirin showed a 35% reduction in ESR. It can be concluded giving cilostazol and aspirin as adjuvant diabetic foot Wagner II and III showed a decrease in ESR. Key words: erythrocyte sedimentation rate, diabetic foot, cilostazol, aspirin. Listen

IDENTIFIKASI BAKTERI PENYEBAB TONSILITIS KRONIK PADA PASIEN ANAK DI BAGIAN THT RSUD ULIN BANJARMASIN Muhammad Nizar; Nur Qamariah; Noor Muthmainnah
Berkala Kedokteran Vol 12, No 2 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Chronic tonsillitis is a condition where tonsil is enlarged, accompanied by repeated infections. Bacterial chronic tonsillitis can be caused by different bacteria, depends on its region. Research for patterns of bacteria causing chronic tonsilitis is needed to determine the target of antibiotics used by hospitals. The general objective of this research was to determine the type of bacteria that cause chronic tonsillitis obtained through a throat swab from pediatric patients in the ENT Ulin Hospital Banjarmasin from August to October 2015. This is a descriptive research using cross sectional approach. The sample in this study is the pediatric patients aged 1-17 years who were diagnosed chronic tonsillitis by ENT specialist at the ENT Ulin Hospital Banjarmasin. Swab was taken from the palatine tonsil and cultured in media isolation and examined using macroscopic, microscopic and biochemical tests. The results showed that 7 isolates of Staphylococcus aureus (53.84%), 1 sample of Escherichia coli (7.69%), and 5 samples of Streptococcus sp. (38.46%) are three major bacteria which infected chronic tonsillitis patients in Ulin GeneraL Hospital Banjarmasin. Keywords: chronic tonsillitis, bacterial identification, pediatric patients Abstrak: Tonsilitis kronis merupakan kondisi di mana terjadi pembesaran tonsil disertai dengan serangan infeksi yang berulang-ulang. Bakteri penyebab infeksi tonsilitis kronis dapat berbeda-beda antar daerah. Perlu adanya penelitian tentang pola kuman agar pemberian antibiotik tepat sasaran.Tujuan umum dalam penelitian ini adalah untuk mengetahui jenis bakteri penyebab tonsilitis kronik yang didapat melalui swab tenggorok pasien anak di bagian THT RSUD Ulin Banjarmasin pada Agustus-Oktober 2015. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan pendekatan cross sectional. Sampel dalam penelitian ini adalah pasien anak umur 1-17 tahun yang didiagnosis tonsilitis kronis oleh dokter spesialis THT di bagian THT RSUD Ulin Banjarmasin. Identifikasi diambil dari swab pada tonsila palatinadan dibiakkan pada media isolasi yaitu dengan pemeriksaan secara makroskopis, mikroskopis, dan uji biokimia. Hasil penelitian menunjukkan terdapat tiga jenis isolat bakteri yaitu Staphylococcus aureus 7 isolat (53,84%), Escherichia coli 1 isolat (7,69%), dan Streptococcus sp. 5 isolat (38,46%). Kata-kata kunci: Tonsilitis kronis, identifikasi bakteri, pasien anak

HUBUNGAN HIGIENITAS BOTOL SUSU DENGAN KEJADIAN DIARE DI WILAYAH PUSKESMAS KELAYAN TIMUR BANJARMASIN Muhammad Fathir Naman Harris; Farida Heriyani; Lisda Hayatie
Berkala Kedokteran Vol 13, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Diarrhea is a contagious disease which still become public health main issue in the world includes Indonesia. South Borneo is in the twentieth province with most frequent diarrhea incident. Kelayan Timur is the second most frequent diarrhea incident public health center in Banjarmasin. One of the risk factors for diarrhea is milk bottle hygiene. This research aimed to understand the correlation between milk bottle hygiene and diarrhea incident in Kelayan Timur Public Health Center. This was analytic observational research with case control study. The data analyzed using a chi square test and prevalence odds ratio. There were 66 samples with 33 samples of case group which showed 21 samples (63,63%) of poor milk bottle hygiene and 12 samples (36,36%) of good milk bottle hygiene meanwhile in control group, there were 11 samples (33,33%) of poor milk bottle hygiene and 22 sample (66,66%) of good milk bottle hygiene. Analysis result shows p value=0,014 and OR=3,5 which means there is significant relation of milk bottle hygiene and diarrhea incident in Kelayan Timur Public Health Center. Infants with poor hygiene milk bottle have 3,5 times higher risk to suffer from diarrhea than infants with good hygiene. Keywords: milk bottle hygiene, diarrhea, Kelayan Timur Public Health Center Abstrak: Diare adalah penyakit infeksi menular yang masih menjadi masalah utama kesehatan masyarakat di seluruh dunia termasuk Indonesia. Kalimantan Selatan menduduki urutan kedua puluh dari semua provinsi yang tercatat sebagai daerah penyumbang diare terbanyak. Kelayan Timur adalah puskesmas dengan kejadian diare terbanyak kedua di Banjarmasin. Salah satu dari faktor risiko diare adalah higienitas botol susu. Penelitian ini bertujuan untuk mengetahui hubungan higienitas botol susu dengan kejadian diare di wilayah Puskesmas Kelayan Timur. Penelitian bersifat observasional analitik dengan pendekatan case control. Analisis data menggunakan uji Chi-square dan prevalence odds ratio.Sampel yang diambil sebanyak 66 sampel, dimana 33 sampel yang diambil sebagai kelompok kasus menunjukkan 21 sampel (63,63%) dengan higienitas botol susu yang buruk dan 12 sampel (36,36%) dengan higienitas botol susu yang baik, sedangkan pada kelompok kontrol terdapat 11 sampel (33,33%) dengan higienitas botol susu yang buruk dan 22 sampel (66,66%) dengan higienitas botol susu yang baik. Hasil analisis mendapatkan nilai p=0,014 dan OR=3,5 sehingga dapat disimpulkan bahwa terdapat hubungan bermakna antara higienitas botol susu dengan kejadian diare di wilayah Puskesmas Kelayan Timur. Balita dengan higienitas botol susu yang buruk berisiko 3,5 kali lebih besar untuk menderita diare dibanding dengan higienitas botol susu yang baik. Kata-kata kunci:higienitas botol susu, diare, Puskesmas Kelayan Timur

PERBEDAAN WAKTU REAKSI PADA USIA LANJUT DENGAN HIPOTENSI ORTOSTATIK DAN TANPA HIPOTENSI ORTOSTATIK Tika Nurullita; Fakhrurazzy Fakhrurazzy; Triawanti Triawanti
Berkala Kedokteran Vol 11, No 2 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Orthostatic hypotension is a common problem in the elderly. High incidence of orthostatic hypotension in elderly associated with decreased baroreceptor sensitivity and declining elasticity and muscle strength inferior. This study aims to determine the differences in reaction time in the elderly with and without orthostatic hypotension in Panti Sosial Tresna Werdha “Budi Sejahtera” Banjarbaru and Martapura. This study was an observational study with cross sectional analytical and decision-purposive sampling technique. Data will be tested for normality prior to the Kolmogorov-Smirnov test for normality. Data analysis using unpaired t test. The results of the study the average reaction time of 30 elderly people with orthostatic hypotension is 2.069 seconds and 30 elderly people without orthostatic hypotension is 1.775 seconds. The results of the Kolmogorov-Smirnov normality test p =0.919 indicates the data are normally. The results of the analysis of the unpaired t test p =0.022 (p <0.05) indicate that there are significant differences. The results that the reaction time in the elderly with orthostatic hypotension longer than without orthostatic hypotension in Panti Sosial Tresna Werdha “Budi Sejahtera” Banjarbaru and Martapura. Keywords: orthostatic hypotension, the elderly, reaction time

CORRELATION TRIGLISERIDA LEVEL AND MONOCYTE IN CORONARY HEART DISEASE AT ULIN GENERAL HOSPITAL BANJARMASIN Gusti Adistya Naila Juwita; Miftahul Arifin; Ida Yuliana
Berkala Kedokteran Vol 13, No 2 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Coronary heart disease (CHD) is an unbalance condition between oxygen supply and demand in heart muscle which caused by coronary artery obstruction known as atherosclerosis. Both triglyceride and monocyte have important role in the process of atherosclerosis plaque forming which cause CHD. This research aimed to analyse correlation between triglyceride level and monocyte count in patients with coronary heart disease at Ulin General Hospital Banjarmasin on August 2014-August 2015. This research is an analytical observational research with cross-sectional approach. Total sample for this research are 94 CHD patients selected by inclusion criteria. The result discovered the average rate for triglyceride level is 114 mg/dL and for monocyte count is 0,62 thousand/µL. Based on result of data analysis with Pearson correlation test demonstrates the value of r=0,347 and p=0,01. It can be concluded that there is weak, significant and positive correlation between triglyceride level and monocyte count in CHD patients Keywords: triglyceride, monocyte, coronary heart disease

PERBEDAAN KADAR KOLESTEROL TOTAL PASIEN PENYAKIT JANTUNG KORONER DENGAN DIABETES MELITUS DAN TIDAK DIABETES MELITUS Desy Puspita Sari; Dewi Indah Noviana Pratiwi; Ida Yuliana
Berkala Kedokteran Vol 11, No 1 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.191

Coronary heart disease (CHD) is the major cause of death in the world.CHD is constriction or occlusion of arteries which supply blood flow to heart muscle with the result lack of blood oxygen supply because atherosclerosis process or spasm or both. The incidence of atherosclerosis at large artheries increase in diabetes melitus (DM) patients.DM is a major risk factor for CHD pathogenesis. One of risk factor for CHD in DM patients is the increase of cholesterol level, a lipid metabolism abnormality.This study aimed to analyze the comparation of total cholesterol between CHD with DM and without DM in RSUD Ulin Banjarmasin period June-August 2014. This study was analytic observational with cross-sectional approach and used consecutive sampling. The total of sample was 60 patients which contain 30 CHD with DM patients and 30 CHD without DM patients. The result showed the mean of CHD with DM patients’s cholesterol total level was 230,50 mg/dL and the mean of CHD without DM patient’s was 197,47 mg/dL.The data anlysis result using independent T-test showed that there is significant difference of cholesterol total level between CHD with DM patients and CHD witout DM patients (p=0,007) in RSUD Ulin Banjarmasin. Keywords: coronary heart disease (CHD), diabetes melitus (DM), total cholesterol

The Influence of Local Wisdom in The Decision Making Process Ermina Istiqomah; Sudjatmiko Setyobudihono; M Azra Inan Abdillah
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: The existence of an authoritative figure is an indivisible part of society living in Indonesia. The high claims of iron tablets in pregnant women were indicated not followed by high consumption of Fe tablets. Motivation was suspected to be a problem in various treatment processes. The aim of this research was to know the level of influence in influencing the decision and also the perception of various influence roles based on the understanding of local wisdom. Descriptive method was used by using a closed questionnaire to 130 respondents. The results showed that the husband, the parents and the mother-in-law were the individuals who had an influence on the decision of a pregnant woman. The need for permission was the highest factor chosen regarding the participation in the health program. This study provides an overview of the influence of individuals that must be considered in making a health program for pregnant women. Keywords: health program, influence of individual, local wisdom, pregnant mother

Kota Layak Anak Berbasis Kesehatan Syamsul Arifin
Berkala Kedokteran Vol 12, No 1 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Health is one of most important point in building child – friendly city. A child needs to know the information about children health, so that they know about source of disease, kinds of disease, and the preventions. Through the given information, step by step a child learns about why a child can get sick and how to prevent it. The result in learning about of learning about children health, a child is going to have a perception about it. In order to create cil – friendly city / district by giving guarantee in continuity for children’s future, public and government are encouraged to fulfill all of children’s right, starting from the right of life, growth, safety, and participation. In a chil – friendly city / district, all of public service which is related to children should give Keywords: child-friendly city, healthy based indicator, action plan Abstark: Kesehatan merupakan salah satu aspek penting dalam mewujudkan kota layak anak. Informasi mengenai kesehatan anak merupakan hal-hal yang perlu diketahui oleh seorang anak, supaya mereka mengetahui sumber penyakit, jenis penyakit dan upaya pencegahannya. Melalui pemberian informasi seorang anak secara bertahap belajar memahami mengapa seorang anak bisa sakit, dan bagaimana mencegahnya. Hasil belajar anak mengenai kesehatan anak, menghasilkan persepsi anak mengenai kesehatan anak. Dalam rangka mewujudkan Kota/Kabupaten Layak Anak dengan memberikan jaminan keberlangsungan masa depan anak, masyarakat dan pemerintah didorong untuk memenuhi seluruh Hak Anak, mulai dari hak hidup, tumbuh kembang, perlindungan dan partisipasi. Dalam Kota/Kabupaten Layak Anak semua pelayanan publik yang berkaiatan dengan anak mesti memberikan pelayanan yang Ramah Anak, sehingga anak-anak yang menerima pelayanan tersebut anak harus merasa aman, nyaman dan gembira. Kata-kata kunci: kota layak anak, indicator berbasis kesehatan, rencana aksi

Monocyte Lymphocyte Ratio, Platelet Lymphocyte Ratio, Neutrophil Lymphocyte Ratio as Prognostic Markers in Patients with Multidrugs Resistant Tuberculosis Treated at Ulin General Hospital Banjarmasin Bagus Wicaksono
Berkala Kedokteran Vol 14, No 2 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Multi Drugs Resistant Tuberculosis (MDR TB) is tubercolusis with the least resistance to rifampicin and isoniazid. The progresivity and side effects of MDR TB treatment can be monitored through clinical, imaging, and laboratory evaluation. Monocyte Lymphocyte Ratio (MLR), Neutrophil Lymphocyte Ratio (NLR), and Platelet Lymphocyte Ratio (PLR) are the inflammatory markers used as biomarkers of treatment progress in MDR TB. The purpose of this research was to determine the difference of MLR, NLR, and PLR value pre and post MDR TB therapy and to determine the best prognostic biomarker in the evaluation of MDR TB treatment progress at Ulin General Hospital in January-December 2017. This research was an analytic observational study with a cross-sectional design. The sample was 17 patients selected based on the inclusion and exclusion criteria. Results obtained from paired T-tests showed the decreasing of MLR, NLR, PLR value in MDR TB patients receiving TB therapy. PLR had a more role as inflammatory biomarker of MDR TB treatment with p = 0.000, compared to MLR (ρ = 0.01), and NLR ( ρ = 0.006). The conclusion is PLR was significantly the best prognostic biomarker for MDR TB treatment. Keywords: MDR TB, Monocyte Lymphocyte Ratio, Neutrophil Lymphocyte Ratio, Platelet Lymphocyte Ratio

Studi Interaksi Farmakodinamik Efek Analgesik Kombinasi Perasan Buah Mengkudu (Morinda citrifolia) dengan Parasetamol: Kajian terhadap waktu reaksi nyeri menggunakan metode hot plate pada mencit (Mus musculus) Firda Wirasari; Mohammad Bakhriansyah; Istiana Istiana
Berkala Kedokteran Vol 10, No 1 (2014)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.927

ABSTRACT: Mengkudu (Morinda citrifolia) has been proven in possessing the analgesic effect. The similarity of analgesic activity of mengkudu and paracetamol enable the existence of analgesic effect interaction synergistically when they are both combined. The objective of this research is to find out the pharmacodynamic interaction between the juice of mengkudu and paracetamol. The research was an experimental research with posttest-only with control group design. The control group consists of 6 groups, and each group had 5 mice. The 1st group was given aquadest 0.5 ml; the 2nd group was given the juice of mengkudu 0.042 mg/g BB; the 3rd group was given paracetamol 0.065 mg/g BB; while the 4th , 5th, 6th groups were given the combination of mengkudu juice 0.042 mg/g BB and paracetamol with the dosages 0.01625 mg/g BB; 0.0325 mg/g BB; 0.065 mg/g BB, respectively. Treatments were given 10 minutes before mice were painly induced by using hot plate. The average of onset of pain for group I, II, III, IV, V, VI were 5.36; 8.28; 8.02; 9.67; 10.5 and 11.74 seconds, respectively. Statistical anaysis using Kruskal Wallis showed that there was significance difference among groups (p = 0.000) while the very potential effect was in group with paracetamol dosage on 0,065 mg/g BB. Based on this research, it can be concluded that there is sinergycal interaction between the combination of mengkudu juice with paracetamol on mice. Keywords : analgesic effect, mengkudu, paracetamol, onset of pain, synergycal interaction ABSTRAK: Mengkudu (Morinda citrifolia) telah terbukti memiliki efek analgesik. Kesamaan aktivitas analgesik buah mengkudu dan parasetamol memungkinkan adanya interaksi efek analgesik yang sinergis ketika keduanya dikombinasikan. Tujuan penelitian ini adalah untuk mengetahui interaksi farmakodinamik efek analgesik kombinasi perasan buah mengkudu dengan parasetamol. Penelitian ini bersifat eksperimental dengan pendekatan posttest-only with control group design, terdiri dari 6 kelompok. Setiap kelompok memiliki 5 ekor mencit. Kelompok I diberikan aquadest 0,5ml, kelompok II diberikan perasan buah mengkudu dengan dosis 0,042 mg/g BB, kelompok III diberikan parasetamol 0,065 mg/g BB sedangkan, kelompok IV, V, VI diberikan kombinasi perasan buah mengkudu 0,042 mg/g BB dan parasetamol dengan dosis masing-masing: 0,01625 mg/g BB; 0,0325 mg/g BB; 0,065 mg/g BB, diberikan 10 menit sebelum dilakukan induksi nyeri di atas hot plate. Rerata waktu reaksi nyeri mencit pada kelompok I, II, III, IV, V, dan VI berturut-turut adalah 5,36; 8,28; 8,02; 9,67; 10,5 dan 11,74 detik. Hasil analisis statistik Kruskal-Wallis menunjukkan bahwa terdapat perbedaan yang bermakna antara berbagai kelompok dengan nilai p = 0,000, dengan dosis kelompok kombinasi yang paling potensial memberikan efek analgesik adalah kelompok dengan dosis parasetamol 0,065 mg/g BB. Berdasarkan penelitian ini dapat disimpulkan bahwa terdapat interaksi yang sinergis pada kombinasi perasan buah mengkudu dengan parasetamol pada mencit. Kata-kata kunci: efek analgesik, buah mengkudu, parasetamol, waktu reaksi, interaksi.

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Editorial Address Jalan Veteran No.128 Banjarmasin

Location Kota banjarmasin, Kalimantan selatan INDONESIA

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Eko Suhartono

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esuhartono@ulm.ac.id

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+6281251126368

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jbk@ulm.ac.id

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Jalan Veteran No.128 Banjarmasin

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Kota banjarmasin,

Kalimantan selatan

INDONESIA