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Published by Universitas Lambung Mangkurat

ISSN : 14120550 EISSN : 25485660 DOI : http://dx.doi.org/10.20527

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 478 Documents

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Klebsiella pneumoniae IDENTIFICATION OF PRODUCING EXTENDED SPECTRUM BETA LACTAMASE (ESBL) AND RESISTANCE PATTERN OF ANTIBIOTICS IN ULIN GENERAL HOSPITAL BANJARMASIN Mayasari, Ayudiah Puspita
Berkala Kedokteran Vol 13, No 2 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v13i2.4071

Abstract: Klebsiella pneumoniae(K. pneumoniae) can synthesize beta lactamase enzymes that have the ability to open lactam beta rings and cause resistance to antibiotics such as amoxicillin, third generation cephalosporins namely cefotaxim, ceftazidim, ceftriaxone and monobactam groups such as aztreonam. Extended spectrum beta lactamase (ESBL) is a plasmid enzyme that mediates the occurrence of hydrolysis and inactivation of beta lactam antibiotics. Infections caused by ESBL-producing bacteria become a serious problem for hospitals worldwide. ESBL isolate susceptibility tests against antibiotics are required to provide a sensitivity pattern that can be used as a reference in more rational antibiotic selection. This study was conducted to describe the prevalence of ESBL group K. pneumoniae and antibiotic resistance pattern at Ulin General Hospital Banjarmasin. The method of this research used secondary data material in the form of reporting document of antibiotic sensitivity test result that isolation and identification using VITEK 2, and then be analyzed using Microsoft Excel. The culture examination toward 50 patients in the Dahlia ward, Ulin General Hospital Banjarmasin was taken from January until May 2017, with the results arefrom 24 data Staphylococius aureus (S.aureus) isolate, more than half of it are ESBL group (54.16%). The results of sensitivity test of K.Pneumoniae of ESBLpositive to antibiotic group were found to be antibiotics that still have> 90% sensitive were meropenem (100%), amikacin (100%), tigecycline (92,85%), ertapenem (92,86%). The antibiotics with resistance> 50% was found in ampicillin antibiotics (100%), ceftriaxone (78.5%), ceftazidime (64.28%), cefepime (57.14%) and aztreonam (71.4%). As for ESBL negative results obtained sensitive> 90% for all antibiotics except ampicillin, ampicillin / sulbactam, and nitrofurantoin. Meropenem (100%), amikacin (100%), tigecycline (92.85%), ertapenem (92.86%) are antibiotic choices that are still sensitive to ESBL infection Keywords: antibiotic resistance, ESBL pattern, Vitek 2

DISTRIBUSI POLA DIET PASIEN KANKER KOLOREKTAL DI RSUD ULIN BANJARMASIN PERIODE AGUSTUS OKTOBER 2015 Rahmadania, Emma; Wibowo, Agung Ary; Rosida, Lena
Berkala Kedokteran Vol 12, No 2 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i2.1872

Abstract: Colorectal cancer is a malignancy of epithelial cells of the colon or rectum. Factors associated with an increased risk of this type of cancer include eating habits. The purpose of this study was to determine distribution the dietary patterns in colorectal cancer patients at hospitals Ulin Banjarmasin period from August to October 2015 by a review of fat dietary, protein dietary, fiber dietaryÂ by age and gender. This research is a descriptive observasional withÂ cross sectional approach. Data was collected using a food frequency questionnaire and interviews. Sampling was conducted with consecutive sampling technique to obtain the sample amounted to 30 patients in accordance with the inclusion criteria. Obtained the age group of patients when first diagnosed with colorectal cancer is highest in the age group 41-60 years (50%) as many as 15 people. Sex ratio of colorectal cancer patients in hospitals Ulin Banjarmasin the period August-October 2015 that men of 15 people (50%) and women of 15 people (50%). Of the 30 respondents, there are 28 (93.4%) patients with colorectal cancer who rarely consume fat, there are 25 (83.4%) patients with colorectal cancer who rarely consume protein, and there were 25 (88.7%) patients with colorectal cancer are rare consuming fiber. Distribution of pattern dietary (fat, protein, fiber)by age and sex obtained the same result that most are in the rare category.Â Keywords: colorectal cancer, fat, protein, fiber.Â Abstrak: Kanker kolorektal adalah suatu keganasan dari sel epitel kolon atau rektum. Faktor yang berkaitan dengan peningkatan risiko kanker jenis ini antara lain kebiasaan makan. Tujuan penelitian ini adalah untuk mengetahui distribusi pola diet pasien kanker kolorektalÂ di RSUD Ulin Banjarmasin periode Agustus-OktoberÂ 2015 dengan tinjauan terhadap diet lemak, diet protein, diet serat berdasarkan usia dan jenis kelamin. Penelitian ini merupakan penelitian yang bersifat deskriptif observasioal dengan pendekatan cross sectional. Data dikumpulkan dengan menggunakan lembar kuesioner food frequency dan wawancara. Pengambilan sampelÂ dilakukan dengan teknik consecutive sampling sehingga didapatkan sampel berjumlah 30 pasien yang sesuai dengan kriteria inklusi. Didapatkan kelompok usia pasien saat pertama kali terdiagnosis kanker kolorektal terbanyak adalah pada kelompok usia 41-60 tahun (50%) yaitu sebanyak 15 orang. Rasio perbandingan jenis kelamin pasien kanker kolorektal di RSUD Ulin Banjarmasin periode Agustus-Oktober 2015 yaitu laki-laki sebanyakÂ 15 orang (50%)Â dan perempuan sebanyak 15 orang (50%). Dari 30 responden, terdapat 28 (93,4%) pasien kanker kolorektal yang jarang mengkonsumsi lemak, terdapat 25 (83,4%) pasien kanker kolorektal yang jarang mengkonsumsi protein, dan terdapat 25 (88,7%) pasien kanker kolorektal yang jarang mengkonsumsi serat. Distribusi pola diet (lemak, protein, serat) berdasarkan usia dan jenis kelamin didapatkan hasil yang sama yaitu paling banyak berada pada kategori jarang.Â Kata-kata kunci: kanker kolorektal, lemak, protein, serat

Platelet to Lymphocyte Ratio Elevation as a Predictor Factor of Degree of Head Injury Andrian Sitompul
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: The inflammatory process of head injury was characterised by the release of pro-inflammatory and inflammatory mediators. This process could be assessed using mediators such as platelet-lymphocyte ratio (PLR) and leukocytes. This study aims to determine the association between PLR and leukocytes in assessing the degree of head injury through the Glasgow coma scale (GCS). This study was an observational analytic study using the medical record of brain-injured patients who visited the Emergency Department of Ulin Hospital from May to November 2017. 59 samples met the criteria in this study. The results of multiple linear regression test in this study found that PLR and leucocyte affected GCS (p = 0.009). The leukocyte value was significantly more associated to GCS (p = 0.008) than PLR value (p = 0.146). The value of leukocyte R was 0.1224, and R PLR was 0.0401. Based on these results, it can be concluded that leukocytes had a better role in predicting the degree of head injury than PLR.

Obstetrical and Non-Obstetrical Factors toward Uterine Prolapse Occurrence in Ulin General Hospital Banjarmasin on Januari – December 2017 Yohanes Adhitya Prakasa Sukoco Putra; Eko Suhartono; Pribakti Budinurdjaja
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Uterine prolapse is a gynecological disease in women that emerge patients physically and psychologically. Uterine prolapse is defined as an uterus herniation inside or outside vagina as the result of the ligament and fascia failure that retain the uterus in its actual place. This research was to identify obstetrical and non-obstetrical factors in uterine prolapses occurrence in Ulin General Hospital Banjarmasin on period January until December 2017 using case control approach. The total sample was 80 medical record samples, which divided into 40 medical record samples of patient with uterine prolapse and 40 medical record samples of patient without the occurrence of uterine prolapse. The results using chi square analysis obtained non-obstetrical factors: age >60 years old (OR 6.67: 95%CI 2.44-18.21), BMI > 30 (OR 3.10: 95%CI 1.24-7.71), menopause (OR 21.00: 95%CI 6.11-72.18); and non-obstetrical factors: parity >4 / multiparity (OR 13.78: 95%CI 4.71-40.28), macrosomia (OR 7.15: 95%CI 2.65-19.34), vaginal delivery (OR 28.78: 95%CI 7.41-111.79). The results of logistic regression obtained non-obstetrical factors: age > 60th (Exp B 4.21 and sig. 0.004), menopause (Exp B 1.12 and sig. 0.001), and multiparity (Exp B 2.35 and sig. 0.016). The results of this analysis obtained that obstetrical and non-obstetrical factors were related to uterine prolapse occurrence, and the dominant factor was age > 60 years old, so it could be concluded that there was significant factor between obstetrical and non-obstetrical factors on uterine prolapse occurrence in Ulin General Hospital Banjarmasin. Keywords: uterine prolapse, obstetrical factor, non-obstetrical factor

Dengue Hemorrhagic Fever: Past, Present, and Future Rahmad Budianto; Niniek Budiarti
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Dengue viral infection is a global disease with a spectrum of clinical manifestations mild fever to severe disease both dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). DHF is severe form of dengue fever (DF), which can be life-threatening. Climate changes is not the only factor that affects dengue transmission, but also globalization changes includes travel and trade. The pathogenesis of dengue infection is complex. The mechanism involved antibody-dependent enhancement, NS1 and its antibodies, T cells, and DENV genomics. There are several novel methods to detect the presence of dengue virus in the body of infected patients. These include ELISA-specific IgM and IgG detection, detection of monoclonal antibodies and mosquito cell strains, and PCR reverse transcriptase detection. Several trials found novel methods to predict the severity of dengue hemorrhagic fever earlier. These include platelet count, Aspartate aminotransferase / platelet count index (APRI) Index, serum chymase level, serum cytokine/chemokine profile, Tropomyosin-alpha 1 (TPM 1), Reticulocyte Production Index (RPI), and Immature Platelet Fraction (IPF). Several pharmacological therapies are known to have potential antidengue effect. Some of these are corticosteroids, antimalarial drugs, doxycycline and tetracycline, anticholesterol drugs, IVIG, celgosivir, balapiravir, pentoxifylline and calcium supplementation. Some natural products are known to have activity against Aedes aegypti through antiviral mechanisms, larvacidal activity, mosquitocidal, and mosquito repellants. It can be developed as the latest therapy of dengue hemorrhagic fever on the future. The objective of this paper is to provide new insight about the development of dengue hemorrhagic fever related to the history of its distribution, pathogenesis, and the latest developments related to detection methods, severity prediction methods, and the management of dengue hemorrhagic fever on the future. Keywords: globalization changes, novel detection methods, severity prediction methods, latest development in DHF therapy

Correlation between Air Temperature and Humidity with the Presence of Aedes aegypti Larvae Farida Heriyani
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Dengue Hemorrhagic Fever (DHF) is a disease that spread by mosquito type Aedes aegypti. The room condition for the water container, such as air temperature and humidity, are factors that influence the presence of Aedes aegypti larvae and whether those are favourable for breeding and their growth to be mature and act as DHF vector. This study aims to know the correlation between environmental factors of the location of the water container, assessed from room temperature and humidity with the presence of Aedes Aegypti larvae in elementary school in Banjarbaru Utara Regency. This is an observational analytic study. Samples obtained were rooms where water container was located in elementary schools in Banjarbaru Utara Regency. Data were then analysed using chi-square. The results are 19.2% rooms with optimum temperature and 85.9% rooms with optimum humidity for the growth of Aedes aegypti larvae. There were 39.1% water containers with no larvae, 12.2% were found few larvae, and 48.7% were found many larvae. From the analysis, there was no significant correlation between room temperature and the presence of Aedes larvae, yet there was found a correlation between air humidity and the presence of Aedes larvae in elementary school in Banjarbaru Utara area.

The Effect of CaCl2 Added PRP (Platelet Rich Plasma) to the Healing Time, Tensile Strength and Adhesion Degree of the Ruptured Tendinopathic Achilles Tendon of Rats (Rattus norvegicus) Istan Irmansyah Irsan; R. Muhammad David Jayanegara
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Achilles tendinopathy produce morbidity, long-lasting disability in athletes and non-athletes and remain a challenge for clinician. Tendinopathy may lead to reduced tensile strength and a predisposition to rupture.The aim of our study was to evaluate the effects of activated and non-activated PRP on the healing process of ruptured tendinopathic achilles tendon in rat. Tendinopathy achilles condition induced by injecting collagenase bacterial type-1 locally. Right achilles tendon in 48 rats ruptured by transecting it transversely and repaired it by using a Kessler technique. Further, the wound immobilized with PRP and injecting activated PRP (5% CaCl2 added) in one group, non-activated PRP on the other group and saline on control group. Tendons from each group were collected at the 1st and 2nd week postoperatively also assessed for biomechanical test. Tendons were also evaluated histologically by using hematoxylin-eosin to know adhesion degree based on Tang criteria. The significant differences was found between intervention group and control (p<0.05) at the 1st week but there was not any significant differences at the 2nd week in tensile strength test (p>0.05). Adhesion degree of the intervention group also reduce better rather than the control at the 1st and 2nd week (p<0.05). PRP have a positive effect on healing tendons by improving healing time, mechanical strength and decreasing adhesion degree. Keywords: achilles tendinopathy, PRP, healing time, tensile strength, adhesion

Orthopedic Case Burden at Nunukan Hospital: Focus On Trauma Case Pandji Winata Nurikhwan; Ahmad Muhsinin; Zairin Noor
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Incidence of orthopedic case is quite high in Nunukan Hospital, most of them need both non-operative and surgical intervention due to congenital, debridement, fracture, rupture of tendon and blood vessel, even amputation. Until now, data orthopedic case profile especially trauma case in Nunukan Hospital is not available. Also, the urgency of having an orthopedic surgeon is unbearable which unavailable in Nunukan, this made the management can’t be done comprehensively and as soon as possible. The aim of this research was to describe the incidence of orthopedic case at Nunukan hospital as basic data for further research. This Retrospective Study was conducted at Nunukan Hospital, North Kalimantan – Indonesia. The data is collected by using logbook and medical records during January 2016 - April 2017. Total of 231 cases were obtained. Male patients accounted for 73.6% (170 patients) and Female was 26.4% (61). The age ranged from 1 day to 82 years old. There are 8-21 cases happened per month (average: 14 cases). Based on case category, trauma occurred for 88.7%% (205). Five top diagnoses are; Close Fracture happened for 44.6% (103 cases), followed by Open Fracture 17.7% (41 cases), Lacerated wound 11.3% (26 cases), Traumatic Amputation 7.4% (17 cases) and CTEV 7.4% (17 cases). Most pathology within the period located in Foot for 29.9% (69). The multiple fracture, vascular, and soft tissue injury were observed. Orthopedic fractures were the most common injuries among patients with 88.7% in Nunukan Hospital from January 2016 to April 2017. There are 14 cases happened for each month with most of the patient were adult. Most of injuries happened at foot region.Abstract: Incidence of orthopedic case is quite high in Nunukan Hospital, most of them need both non-operative and surgical intervention due to congenital, debridement, fracture, rupture of tendon and blood vessel, even amputation. Until now, data orthopedic case profile especially trauma case in Nunukan Hospital is not available. Also, the urgency of having an orthopedic surgeon is unbearable which unavailable in Nunukan, this made the management can’t be done comprehensively and as soon as possible. The aim of this research was to describe the incidence of orthopedic case at Nunukan hospital as basic data for further research. This Retrospective Study was conducted at Nunukan Hospital, North Kalimantan – Indonesia. The data is collected by using logbook and medical records during January 2016 - April 2017. Total of 231 cases were obtained. Male patients accounted for 73.6% (170 patients) and Female was 26.4% (61). The age ranged from 1 day to 82 years old. There are 8-21 cases happened per month (average: 14 cases). Based on case category, trauma occurred for 88.7%% (205). Five top diagnoses are; Close Fracture happened for 44.6% (103 cases), followed by Open Fracture 17.7% (41 cases), Lacerated wound 11.3% (26 cases), Traumatic Amputation 7.4% (17 cases) and CTEV 7.4% (17 cases). Most pathology within the period located in Foot for 29.9% (69). The multiple fracture, vascular, and soft tissue injury were observed. Orthopedic fractures were the most common injuries among patients with 88.7% in Nunukan Hospital from January 2016 to April 2017. There are 14 cases happened for each month with most of the patient were adult. Most of injuries happened at foot region.

Differences in Age and Body Mass Index of Women with Polycystic Ovary Syndrome Attending in Vitro Fertilization (IVF) Program Roselina Panghiyangani; Husnul Khatimah; Dwi Anita Suryandari; Budi Wiweko; Mala Kurniati
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Nutritional status in this case BMI in women is very important in relation to infertility problems in women of reproductive age. Polycystic ovary syndrome (PCOS), is a reproductive problem with hormonal disorders. Infertility Female with PCOS is associated with anovulation, high LH and hyperandrogenism. The purpose of this study was to analyze differences in age and body mass index (BMI) of PCOS women undergoing in vitro fertilization (IVF). This was an observational analytic study. The subjects of the study were women aged 30-40 years who undergoing IVF-assisted fertilization program at Yasmin Clinic - RSCM Kencana who was diagnosed as PCOS. As a comparison are women 30-40 years who have infertility problems but not PCOS who underwent IVF-assisted fertilization program. Women diagnosed with PCOS based on the Rotterdam 2003 consensus definition, and reinforced with ultrasound examinations that show polycystic ovary symptoms. Diagnosis is performed by a specialist in Obstetrics and Gynecology. Age data is taken from medical record and IMT data is calculated based on formula body weight/height2. Data analysis was done by unpaired t test. Mean age of study subjects: 32.21 ± 0.99 years female PCOS and 32.80 ± 0.516 years of non-PCOS group of women, unpaired t-test results were not significantly different (p> 0.05). Mass Index PCOS group 24.425 ± 0.585 Kg/m2 and 22.840 ± 0.494 Kg/m2 non-PCOS group, unpaired t-test results were significantly different (p <0.05). Conclusion of this research was in the PCOS women group had significantly higher BMI rates than the group non PCOS woman.

Concomitant Distal Radioulnar Joint Disruption in Distal End Radius Fracture Cases Admitted to Emergency Ward Hasan Sadikin Hospital January 2013 – December 2015 Tody Pinandita; Herry Herman; Yoyos Dias Ismiarto
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: The distal end radius and ulna is an integral part of the wrist joint and preservation of its normal anatomy is essential for the mobility of the wrist. The most common cause of residual wrist disability after distal end radius fractures is the disruption of distal radioulnar joint (DRUJ). Early recognition and management in the acute stage aim at the anatomic reconstruction of the DRUJ in an effort to reduce incidence of chronic pain and loss of wrist motion. The purpose of this study is to identify the prevalence of accompanying DRUJ in distal end radius fracture cases, highlighting its significance in occurance. This was a retrospective study with an analytic descriptive method and data from January 2013-December 2015 taken from medical records of Dr. Hasan Sadikin Hospital. From research, we found 74 cases of distal end radius fracture. The most common injured wrist were dominant hand as 46 cases (62,2%), and non-dominant hand as 28 cases (37,8%). From all data, DRUJ disruption were marked as 37 cases (50%). Extraarticular fracture with concomitant DRUJ disruption were marked in 3 cases (8,1%) and in intraarticular involvement were 34 cases (91,9 %). From this study, we can conclude that half of the distal end radius fracture cases, especially intraarticular, were accompanied by DRUJ disruption. This should be an issue to be concerned by the physician when evaluating distal end radius fracture cases and to perform proper treatment.

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Eko Suhartono

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Home Page

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Contact Name Eko Suhartono

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Editorial Address Jalan Veteran No.128 Banjarmasin

Location Kota banjarmasin, Kalimantan selatan INDONESIA

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Contact Name
Eko Suhartono

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esuhartono@ulm.ac.id

Phone
+6281251126368

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jbk@ulm.ac.id

Editorial Address
Jalan Veteran No.128 Banjarmasin

Location
Kota banjarmasin,

Kalimantan selatan

INDONESIA