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Berkala Kedokteran
Published by Universitas Lambung Mangkurat
ISSN : 14120550     EISSN : 25485660     DOI : http://dx.doi.org/10.20527
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 478 Documents
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Perbandingan Efektifitas Rapid Diagnostic Test (Rdt) Dengan Pemeriksaan Mikroskop Pada Penderita Malaria Klinis : Di Kecamatan Jaro M. Aulia Rakhman; Istiana Istiana; Nelly Al Audhah
Berkala Kedokteran Vol 9, No 1 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.631 KB) | DOI: 10.20527/jbk.v9i1.916

Abstract

ABSTRACT: Malaria is a disease caused by genus Plasmodium. Enforcement of the diagnosis malaria is microscopic examination of thick blood droplets and thin blood droplets and examination of Rapid Diagnostic Test (RDT). Gold standard for the diagnosis of malaria is microscopic examination. Rapid Diagnosis Test (RDT) is one alternative diagnostic tool in detecting Plasmodium quickly and doesn’t require special skill. The purpose of this study was to discover the effectiveness of Rapid Diagnostic Test (RDT) compared with microscopic examination in patient with clinical malaria in Jaro Sub-district. This study was a descriptive analytic study using the data of the result of malaria examination means of microscope examination and RDT on January – June 2012, with cross sectional approach. RDT examination result showed 98% sensitivity value, 100% specificity value, 100% positive predictive value and 98% negative predictive value compared with microscopic examination. Statistical test using Mc.Nemar test with 95% level of confidence interval p=0,125 (p>0,05). This show was no difference in the effectiveness of RDT examination and microscopic examination of patients with clinical malaria in Jaro Sub-district.Keywords: effectiveness, Rapid Diagnostic Test (RDT), microscopic examinationABSTRAK: Malaria adalah penyakit yang disebabkan oleh genus Plasmodium. Penegakkan diagnosis malaria adalah dengan pemeriksaan mikroskopis berupa tetesan darah tebal dan tetesan darah tipis serta pemeriksaan Rapid Diagnostik Test (RDT).  Gold standard untuk diagnosis malaria adalah dengan pemeriksaan mikroskopis. Rapid Diagnosis Test (RDT) merupakan salah satu alat diagnostik alternatif dalam mendeteksi Plasmodium secara cepat dan tidak memerlukan keterampilan khusus. Tujuan penelitian ini untuk mengetahui efektifitas Rapid Diagnostic Test (RDT) dibandingkan dengan pemeriksaan mikroskop pada penderita malaria klinis di Kecamatan Jaro. Penelitian ini merupakan penelitian deskriptif analitik menggunakan data hasil pemeriksaan malaria melalui pemeriksaan mikroskop dan RDT selama bulan Januari – Juni 2012 dengan pendekatan cross sectional. Hasil penelitian menunjukkan pemeriksaan RDT memiliki nilai sensitivitas 98%, spesifisitas 100%, nilai duga positif 100% dan nilai duga negatif 98% dibandingkan dengan pemeriksaan mikroskopis. Analisis uji statistik menggunakan uji Mc.Nemar dengan tingkat kepercayaan 95% didapatkan nilai p=0,125 (p>0,05)S. Hal ini menunjukkan tidak terdapat perbedaan efektifitas  pemeriksaan RDT dan mikroskopik pada penderita malaria klinis di Kecamatan Jaro.. Kata-kata kunci: efektifitas, Rapid Diagnostic Test (RDT), pemeriksaan  mikoskopisABSTRACT: Malaria is a disease caused by genus Plasmodium. Enforcement of the diagnosis malaria is microscopic examination of thick blood droplets and thin blood droplets and examination of Rapid Diagnostic Test (RDT). Gold standard for the diagnosis of malaria is microscopic examination. Rapid Diagnosis Test (RDT) is one alternative diagnostic tool in detecting Plasmodium quickly and doesn’t require special skill. The purpose of this study was to discover the effectiveness of Rapid Diagnostic Test (RDT) compared with microscopic examination in patient with clinical malaria in Jaro Sub-district. This study was a descriptive analytic stud
Perbedaan Efektivitas antara Cilostazol dan Aspirin terhadap Peningkatan Suhu Sela Jari: Tinjauan terhadap Kaki Diabetik Wagner Derajat II dan III Muhammad Akbar 'Anifa; Zairin Noor; Nelly Al Audhah
Berkala Kedokteran Vol 10, No 1 (2014)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.932

Abstract

ABSTRACT: Diabetes mellitus is a multisystem disease characterized by hyperglycemia due to abnormalities in insulin secretion, insulin mechanism, or both. Hyperglycemia in diabetes will lead to long-term complications, such as, several organs failure or disfunction, especially the eyes, kidneys, nerves, heart and blood vessels. One of the diabetic complications is diabetic foot. The appearance of diabetic foot mainly occurs due to repetitive trauma to the foot. After the appearance of ulcers, diabetic foot was compounded with decreased vascular in the patients, making it more difficult to recover. The poor vascularization for diabetic foot patients implicates falling temperatures of the toes. Cilostazol and aspirin are antithrombotic medicines that cause inhibition activation and aggregation trombosit, and vasodilatation. This study aimed to examine the effect of cilostazol and aspirin on toes temperature of the feet of diabetic patients. This research is an experimental research by calculating the average temperature of the toes of diabetic foot patients before and after the administration of cilostazol and aspirin . The results showed the average temperature of the subject toes before giving cilostazol and aspirin is 33.340C and 33.970C, and after administration is 33.540C and 34.720C. From this research it can be concluded that there is an increase in the temperature of the toes after administration of cilostazol and aspirin on the toes of diabetic foot patients. Keywords : Aspirin, Cilostazol, Diabetes Mellitus, Diabetic Foot ABSTRAK: Diabetes mellitus merupakan suatu penyakit multisistem dengan ciri hiperglikemia akibat kelainan sekresi insulin, kerja insulin, atau kedua-duanya. Hiperglikemia pada diabetes akan mengakibatkan komplikasi jangka panjang seperti, disfungsi atau kegagalan beberapa organ tubuh, terutama mata, ginjal, saraf, jantung dan pembuluh darah. Salah satu komplikasinya adalah kaki diabetik. Kemunculan kaki diabetik terutama terjadi karena adanya trauma berulang pada kaki. Setelah munculnya ulkus, kaki diabetik diperparah dengan daya vaskuler pasien yang menurun, sehingga sulit untuk sembuh. Buruknya vaskularisasi pasien kaki diabetik berimplikasi pada turunnya suhu sela jari kaki. Cilostazol dan aspirin adalah obat antitrombotik yang menyebabkan terjadinya inhibisi aktivasi dan agregasi trombosit, serta vasodilatasi. Penelitian ini bertujuan untuk melihat pengaruh cilostazol dan aspirin terhadap suhu sela jari kaki pada pasien kaki diabetik. Penelitian ini bersifat eksperimental dengan menghitung rata-rata suhu sela jari kaki pasien kaki diabetik sebelum dan setelah pemberian cilostazol dan aspirin. Hasil penelitian menunjukkan rata-rata suhu sela jari kaki subyek sebelum pemberian cilostazol dan aspirin adalah 33,340C dan 33,970C, dan setelah pemberian adalah 33,540C dan 34,720C. Dari hasil penelitian dapat disimpulkan bahwa terdapat peningkatan suhu sela jari kaki setelah pemberian cilostazol dan aspirin pada sela jari kaki pasien kaki diabetik. Kata-kata Kunci : Aspirin, Cilostazol, Diabetes Mellitus, Kaki Diabetik.
Gambaran Distribusi Penderita Gangguan Jiwa Di Wilayah Banjarmasin Dan Banjarbaru Tahun 2011 Al Furqonnata Mubarta; Achyar Nawi Husein; Syamsul Arifin
Berkala Kedokteran Vol 9, No 2 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i2.950

Abstract

ABSTRACT: One of the causes mental disorders are sociodemographic factors that include: age, gender and population density. Banjarmasin and Banjarbaru city has a high population density, this affecting the distribution of mental disorders. this Research is to find the distribution of mental disorders in Banjarmasin and Banjarbaru. This research use a descriptive method using secondary data of mental disorders in 2011 that was in Banjarmasin and Banjarbaru Health Department. The result, found that the number of people with mental disorders in Banjarmasin: psychosis 33%; non psychosis 67%; highest age 31-40 years 31.07%, women 60.20%, men 39.80% and highest in Kecamatan Banjarmasin Selatan 23.25%. The number of people with mental disorders in Banjarbaru: psychosis, 72%, non psychosis 28%; highest age > 50 years 27.80%, women 60.76%, men 39.24% and highest in Banjarbaru Selatan 51.12%. From the above results, there are some differences in the distribution of mental disorders in Banjarmasin and Banjarbaru in 2011. Keywords: mental disorder, age, gender, population density.ABSTRAK: Salah satu penyebab gangguan jiwa adalah faktor sosiodemografi yang meliputi; usia, jenis kelamin dan kepadatan penduduk. Kota Banjarmasin dan Banjarbaru merupakan wilayah yang memiliki tingkat kepadatan penduduk yang tinggi, sehingga mempengaruhi distribusi gangguan jiwa. Tujuan penelitian untuk mengetahui distribusi penderita gangguan jiwa di wilayah Banjarmasin dan Banjarbaru. Penelitian ini menggunakan metode deskriptif dengan menggunakan data sekunder gangguan jiwa tahun 2011 yang berada di Dinas Kesehatan Banjarmasin dan Banjarbaru. Hasil dari penelitian didapat bahwa jumlah penderita gangguan jiwa di Banjarmasin: psikosis 33%; non psikosis 67%; usia terbanyak 31-40 tahun 31,07%; perempuan 60,20%; laki-laki 39,80% dan terbanyak pada Kecamatan Banjarmasin Selatan 23,25%. Jumlah penderita gangguan jiwa di Banjarbaru: psikosis 72%; non psikosis 28%; usia terbanyak >50 tahun 27,80%; perempuan 60,76%; laki-laki 39,24% dan terbanyak pada Kecamatan Banjarbaru Selatan 51,12%. Dari hasil di atas, terdapat beberapa perbedaan distribusi penderita gangguan jiwa di Banjarmasin dan Banjarbaru tahun 2011. Kata-kata kunci: gangguan jiwa, usia, jenis kelamin, kepadatan penduduk.
Gambaran Kejadian Insomnia pada Wanita Menopause di Kelurahan Teluk Dalam Tahun 2013: Kajian Berdasarkan Usia Responden dan Lama Menopause Devita Wijayanti; Achyar Nawi Husein; Syamsul Arifin
Berkala Kedokteran Vol 10, No 2 (2014)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.966

Abstract

ABSTRACT: Insomnia is a sleep disorder which manifest as difficulty to start sleep, difficulty to maintain sleep or wake up with feeling of dissatisfied sleep. Women showed the higher prevalence of insomnia than men due to the occurrence of menopause is associated with declining of estrogen levels in postmenopausal women. The aim of this study was to describe the incidence of insomnia in menopausal women based on menopausal age and menopausal periode in Teluk Dalam Area in Banjarmasin 2013 . The research method was descriptive with  cross - sectional approach . The number of samples according to Fraenkel and Wallen were 100 people with cluster random sampling technique. The results between menopausal women showed 60 % had insomnia and 40 % did not have insomnia . Based on the menopausal age, the incidence of insomnia in menopausal women aged 45-46 years old were 6.7 % , 47-48 years old were 8.3 % , 49-50 years old were 13.3 % , 51-52 years old were 8.3 % , 53-54 years old were 15 % and the most common age were 55 years as 48.4%. Based on the menopausal periode, 58.3%  women who experienced insomnia were less than five years and 41.7% were more than five years. It can be concluded that the most common age of woman who experienced insomnia was 55 years old and the most common menopausal periode of woman who experienced insomnia was less than 5 years.Key words: menopause, insomnia, usia, periode menopause. ABSTRAK: Insomnia merupakan gangguan tidur yang dapat berupa kesulitan untuk memulai tidur, kesulitan mempertahankan tidur atau bangun pagi dengan perasaan tidak puas tidur. Wanita menunjukkan prevalensi insomnia lebih sering dibanding pria disebabkan terjadinya menopause yang berhubungan dengan menurunnya kadar estrogen pada wanita menopause. Tujuan penelitian ini untuk mengetahui gambaran kejadian insomnia pada wanita menopause berdasarkan usia menopause dan lama menopause di Kelurahan Teluk Dalam Banjarmasin Tahun 2013. Metode penelitian adalah deskriptif dengan pendekatan cross-sectional. Jumlah sampel menurut Fraenkel dan Wallen sebanyak 100 orang dengan teknik pengambilan sampel cluster random sampling. Hasil penelitian menunjukkan 60% mengalami insomnia dan 40% tidak mengalami insomnia. Berdasarkan usia menopause yang dialami, kejadian insomnia pada wanita menopause usia 45-46 tahun sebanyak 6,7%, usia 47-48 tahun sebanyak 8,3%, usia 49-50 tahun sebanyak 13,3%, usia 51-52 tahun sebanyak 8,3%, usia 53-54 tahun sebanyak 15% dan paling banyak terjadi pada usia 55 tahun sebanyak 48,4%. Jumlah responden yang mengalami insomnia berdasarkan lama menopause, maka pada wanita yang mengalami menopause kurang dari lima tahun sebanyak 58,3% dan pada wanita menopause lebih dari lima tahun sebanyak 41,7%. Kesimpulan penelitian ini yaitu jumlah wanita menopause yang paling banyak mengalami insomnia adalah pada usia 55 tahun dan pada wanita yang mengalami menopause  kurang dari 5 tahun. Kata-kata kunci: menopause, insomnia, age, menopausal periode
Perbedaan Kadar Advanced Oxidation Protein Products (AOPP) Ovarium Tikus Putih (Rattus norvegicus) yang Terpajan Kadmium dan Tidak Terpajan Kadmium Endah Ayu Rahmadhani; Eko Suhartono; Meitria Syahadatina Noor
Berkala Kedokteran Vol 10, No 1 (2014)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.935

Abstract

Abstract: Cadmium ( Cd) is one of hazardous and  poisonous material, which is that every material because of the nature of concentration or amount either directly or indirectly, can pollute the environment, health, the life of human beings and other living creatures. Cadmium induces toxicity or giving rise to a toxic effect through its ability in the formation of various free radical. An increase of free radicals that excessive will trigger oxidative stress. Advanced Oxidation Protein Products (AOPP) is one of the makers of the occurrence of oxidative stress, derived from the influence of oxidative, stress carbonyl, and increasing the activity of inflammatory globally. This research is an experimental laboratoric the study was performed with 2 groups the treatment, first is  the control group P(0) that does not given exposure cd have been given 2 mL/day aquadest for 4 weeks, and the group exposure P(1), who is given exposure of  Cd with concentration  6 mg Cd/L given 2 mL/day for 4 weeks. The results showed average levels of AOPP in the control group P (0) was 5,319 ± 2,540 µM and  exposure group P(1) has an average of 9,360 ± 1,727 µM AOPP levels. Statistical analysis of the results of the Mann-Whitney shows that there is a meaningful difference between a group with a value of p = 0.000. Can be concluded there that effect of the difference of the formation a both group of AOPP, which in AOPP levels  exposure is higher than the control group. Keywords: cadmium, ovarium, Advanced Oxidation Protein Products, oxidative stress.  Abstract: Kadmium (Cd) merupakan salah satu bahan berbahaya dan beracun yaitu setiap bahan yang karena sifat, konsentrasi atau jumlah, baik secara langsung maupun tidak langsung, dapat mencemari lingkungan hidup, kesehatan, kelangsungan hidup manusia serta mahluk hidup lain. Kadmium menginduksi toksisitas atau menimbulkan efek toksik melalui kemampuannya dalam pembentukan berbagai radikal bebas. Peningkatan radikal bebas yang berlebihan akan memicu terjadinya stres oksidatif. Advanced Oxidation Protein Products (AOPP) merupakan salah satu tanda-tanda terjadinya stres oksidatif, yang berasal dari pengaruh oksidatif, stres karbonil, dan peningkatkan aktivitas inflamasi secara global. Penelitian ini bersifat studi eksperimental laboratorik yang dilakukan dengan 2 kelompok perlakuan, yaitu kelompok kontrol P(0) yang tidak diberi pajanan Cd hanya diberi akuadest sebanyak 2 mL/hari selama 4 minggu dan kelompok pajanan P(1) yang diberi pajanan Cd dengan konsentrasi 6 mg Cd/L yang diberikan sebanyak 2 mL/hari selama 4 minggu. Hasil penelitian menunjukkan rerata kadar AOPP pada kelompok kontrol P(0) adalah 5,319 ± 2,540 µM dan kelompok pajanan P(1) memiliki rerata kadar AOPP sebesar 9,360 ± 1,727 µM. Hasil analisis statistik Mann-Whitney menunjukkan bahwa terdapat perbedaan yang bermakna antara kelompok dengan nilai p = 0,000. Dapat disimpulkan terdapat pengaruh perbedaan pembentukan AOPP terhadap kedua kelompok, dimana kadar AOPP pada kelompok pajanan lebih tinggi dibanding kelompok kontrol. Kata-kata kunci: kadmium, ovarium, Advanced Oxidation Protein Products, stres oksidatif.
Antifospholipid Syndrome with Autoimun Hemolitic Anemia Muhammad Huki Zukhrufan; Irza Wahid
Berkala Kedokteran Vol 16, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.329 KB) | DOI: 10.20527/jbk.v16i1.8102

Abstract

Abstract: Antiphospholipid syndrome is a part of systemic autoimmune disease (nonspecific organ), characterized by vascular thrombosis (arterial or venous) with a high antibody titter against a plasma protein that binds to phospholipid anions (antiphospholipid-aPL antibodies). Autoimmune haemolytic anaemia (AIHA) is rare in patients with antiphospholipid antibody syndrome. A sixteen years old female patient has been reported with the main complaint of swelling in the right leg. The patient also complained of increased fatigue. On physical examination found anaemic conjunctiva, swelling in the right limb with a diameter of the right leg greater than the left leg. Homan’s sign positive on the right leg. This patient belongs to the high probability criteria of DVT. Doppler Ultrasonography (USG) examination suggests thrombus in the iliac vein, femoral vein, and right leg popliteal vein, and thrombus in the left leg popliteal vein. In the antibody anticardiolipin (ACA) IgG examination an increase was found. The comb test was positive, and haemolytic anaemia antibody screening was the warm type. Heparinisation and immunosuppressant administration were performed in patients. The incidence of antiphospholipid syndrome with AIHA cannot be ascertained whether there is a direct relationship. Keywords: antiphospholipid syndrome, DVT, AIHA
Efek Pajanan Kadmium (Cd) terhadap Kadar Malondialdehyde (MDA) pada Ovarium Tikus Putih (Rattus norvegicus) Muhammad Hendy Arizal; Eko Suhartono; Mohammad Bakhriansyah
Berkala Kedokteran Vol 10, No 2 (2014)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.953

Abstract

ABSTRACT: Cadmium (Cd) is heavy metal that pollutant in the environment. Chronic intake of Cd induces toxicity on liver, kidney, and ovary. Cd could damage the tissue with stress oxidative damage mechanism. Malondyaldehyde (MDA) is the product of lipid peroxidation used as a measure of lipid peroxidation and stress oxidative damage. This was an experimental laboratoric using two groups. The control group P(0) was given aquadest 2 ml per day for 4 weeks and the exposure group P(1) was given a solution of Cd with a concentration of 1.2 x 10-2 mg for 4 weeks. The results showed the mean of MDA level in the P(0) and the P(1) were 214.80 μM and 232.00 μM, respectively. Statistical analysis using Unpaired Test-T obtained the result p = 0.016 (p<0.05). It can be concluded that Cd causes increased MDA levels in rats ovary. Keywords: Cadmium, malondialdehyde, ovarium, oxidative stress, rats. ABSTRAK : Kadmium (Cd) merupakan logam berat bersifat polutan yang mencemari lingkungan. Paparan kronik Cd berefek toksik terhadap hati, ginjal, dan ovarium. Cd merusak jaringan melalui mekanisme stres oksidatif. Malondialdehyde (MDA) merupakan produk akhir dari peroksidasi lipid  yang menjadi parameter dalam mengukur kerusakan oksidatif. Penelitian ini bertujuan untuk mengetahui efek pajanan Cd terhadap kadar MDA ovarium tikus putih. Penelitian ini bersifat eksperimental laboratorik yang dilakukan pada 2 kelompok, yakni kelompok kontrol P(0) yang diberi aquadest sebanyak 2 ml selama 4 minggu dan kelompok perlakuan P(1) yang diberi Cd dengan konsentrasi 1,2 x 10-2 mg dalam 2 ml aquadest setiap hari selama 4 minggu. Hasil penelitian didapatkan rerata pada kelompok kontrol P(0) sebesar 214,80 ± 22,90 μM dan pada kelompok perlakuan P(1) sebesar 232,00 ± 20,40 μM dengan nilai p = 0,016 (p<0,05). Dapat disimpulkan bahwa Cd menyebabkan peningkatan kadar MDA pada ovarium tikus putih. Kata-kata kunci: Kadmium, malondialdehyde, ovarium, stres oksidatif, tikus putih. 
POTENTIAL ETHANOL OF Carica papaya L. EXTRACT AS IMMUNOMODULATORY THROUGH HISTOLOGY OBSERVATION AT MICE BALB/C SPLEEN Sri Tasminatun; Ria Pravitasari; SN. Nurul Makiyah
Berkala Kedokteran Vol 13, No 2 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.652 KB) | DOI: 10.20527/jbk.v13i2.4077

Abstract

Abstract: The diameter of the alba pulp of the spleen will be enlarged, when the body responds to allergens by increasing the activity of the immune system. Papaya fruits (Carica papaya L.) containing flavonoid that can be as an immunomodulator. This study aims to determine the effect of C. papaya extract to the diameter size alba pulp of the spleen of Ovalbumin (OVA) induced Balb/C mice. The research design was experimental in vivo animal test with post-test only control group design. Thirty male Balb/C mice, ±20grams weight, 8 weeks old, divided into six groups consists of a normal control, negative control, Methylprednisolone, and C. papaya extract treatment group (175mg/kg, 350mg/kg and 700mg/kg dose per day). The extract and Methylprednisolone are given for 28 days, while OVA is given on 15thand 22ndday (intraperitoneal,) and 23rd until 28thday (peroral). On the 29thday the mice are sacrificed and the duodenum was made into histological preparation with HE staining. The immunomodulator effect is assessed by the average of the diameter size alba pulp of the spleen under a light microscope. The data were analyzed using SPSS15 with one way ANOVA continued with Tukey test. The average of the diameter size alba pulp of the spleen for control group is 10,165 ± 0,195; negative control group is 30,357 ± 0,826; methylprednisolone group is 10,220 ± 0,346; 175mg/kgbb dose extract is 14,956 ± 1,057; 350mg/kgbb dose extract is 14,030 ± 0,667; and 700mg/kgbb dose extract is 12,504 ± 0,729. The conclusion of this study is Carica papaya L. extract treatment group (175mg/kg, 350mg/kg and 700mg/kg dose per day) has an effect to the average of the diameter size alba pulp of the spleen in OVA-induced Balb/C mice significantly. 700mg/kg dose per day has the same effect with the methylprednisolone group. Keywords: immunomodulator, Carica papaya L., alba pulp of the spleen, ovalbumin
Pengaruh Insuflasi terhadap Jumlah Sel Mast Peritoneum Tikus Muhammad Halim Fathoni; Zairin Noor; Hery Poerwosusanto
Berkala Kedokteran Vol 12, No 1 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (384.591 KB) | DOI: 10.20527/jbk.v12i1.355

Abstract

Abstract:Peritoneal insufflation is swelling process to perform laparoscopic surgery, the choice of gas for insufflation in laparoscopic surgery, namely CO2. because it is not flammable bleak N2O, so it can be used safely for diathermy in mice. This study aims to determine whether there is influence insufflation in an increased number of mast cells in rats (Rattus norvegicus). This study is pure experimental research with posttest-only control group design, which consists of the control and treatment of pressure 8 mmHg and 10 mmHg, with the results obtained p0 control = 0.52 p1 8 mmHg = 7.84  p2 10 mmHg = 11.94. ANOVA test showed that the increase in the number of mast cells was significantly occurred in the group with a pressure of 10 mmHg as compared to the pressure of 8 mmHg. Based on research carried out can be concluded that the higher the CO2 gas in the insufflation pressure significantly increases the number of mast cells.Keywords: insuflation, peritoneal, cell Mast Abstrak: Insuflasi adalah proses penggembugan peritoneum untuk melakukan pembedahan laparoskopi, pilihan gas untuk insuflasi pada bedah laparoskopi yaitu CO2. karena tidak mudah terbakar seprti N2O, sehingga dapat digunakan secara aman untuk diatermi pada tikus. Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh insuflasi dalam peningkatan jumlah sel mast pada tikus putih (Rattus norvegicus). penelitian ini merupakan penelitian experimental murni dengan posttest-only with control group design, yang terdiri dari kontrol dan perlakuan dengan tekanan 8 mmHg dan 10 mmHg, dengan hasil yang didapatkan p0 kontrol = 0,52 p1 8 mmHg = 7,84 p2 10 mmHg=11,94. Uji anova menunjukan bahwa peningkatan jumlah sel mast secara bermakna terjadi pada kelompok dengan tekanan 10 mmHg dibandingkan dengan tekanan 8 mmHg. Berdasarkan penelitian yang dilakukan dapat diambil kesimpulan bahwa semakin tinggi tekanan gas CO2 pada insuflasi secara bermakna dapat meningkatkan jumlah sel mast. Kata-kata Kunci :Insuflasi, sel mast, peritoneum
Analysis the Age of Pregnant Woman and Stages of Hypertension as Risk Factors of Preeclampsia Eclampsia on Pregnant Women in Dr. Murjani General Hospital Sampit at June Periode 2018 Herli Gustiani
Berkala Kedokteran Vol 14, No 2 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.592 KB) | DOI: 10.20527/jbk.v14i2.5307

Abstract

Abstract: Preeclampsia is a syndrome characterized by an increase in blood pressure and proteinuria that appears in the second trimester of pregnancy which is always recovered in the postnatal period. Preeclampsia can be influenced by many factors, but the analysis of risk factors for preeclampsia in Dr. Murjani Hospital has never been done, especially in relation to the pregnant women age, history of pregnancy, abortion, and stages of hypertension. Thus, this research needs to be done. This research was analytical study with cross sectional approach, which aims to explain the relationship between the age of pregnant women and the stages of hypertension with preeclampsia. Research subjects were patients who came to Dr. Murjani Hospital on 28 May-9 June 2018. Data were collected from the Medical Record section and analyzed by t-test to compare the average of two groups (normal and preeclampsia). Chi Square test with 95% confidence interval was used to find out the relationship between two variables. The results showed that there was no relationship between the age of pregnant mother with preeclampsia incident in Dr. Murjani Hospital, but the stages of hypertension is related with preeclampsia incident in Dr. Murjani Hospital. Keywords: preeclampsia, stage of hypertension, the age of pregnant women

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