Majalah Obstetri dan Ginekologi
Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.
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<![CDATA[Green tea extract reduces insulin level and folliculogenesis in insulin-resistant PCOS rats model ]]>
<![CDATA[Irma Maya Puspita]]>;
<![CDATA[Budi Santoso]]>;
<![CDATA[Budi Utomo]]>
<![CDATA[ Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/mog.V27I32019.103-107
<![CDATA[Objectives: Polycystic ovary syndrome (PCOS) is an endocrine disorder with still unknown pathophysiology. Insulin resistance is one of major factors that affect the pathogenesis of PCOS (69%). Green tea has compounds that can be used to improve the condition of insulin resistance, so that folliculogenesis may recur in the case of PCOS.Materials and Methods: The subjects in this study were rats which were divided into 5 groups, consisting of 2 groups serving as a control group (negative and positive) and 3 groups as the treatment group. Each group consisted of 7 experimental animals. Negative control group was given with distilled water for 14 days. Positive control group was given with injections of testosterone propionate 1 mg/100 g BW intramuscularly in the thigh for 28 days to obtain a model of insulin-resistant PCOS and the distilled water was used as therapy. The treatment groups were given wth injections of testosterone propionate 1 mg/100gBW intra-muscularly for 28 days and then treated with green tea extract in doses of each 200 mg/kg, 400 mg/kg, and 800 mg/kg for 14 days. Rats were dissected on day 42 for harvesting the right and left ovary and heart blood sample was taken for examining insulin levels.Results: The results showed that administration of green tea extract on K5 can reduce insulin levels and increase folliculogenesis significantly (significance p <0.05).Conclusion: Green tea extract can reduce insulin levels and increase folliculogenesis in rats. PCOS - Insulin resistance at a dose of 800 mg/kg.]]>
<![CDATA[Relationship between BMI and β-hCG levels with hyperemesis gravidarum in Manado, Indonesia ]]>
<![CDATA[Inne Mamesah]]>;
<![CDATA[Maria Loho]]>;
<![CDATA[Eddy Suparman]]>
<![CDATA[ Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/mog.V27I32019.108-113
<![CDATA[Objectives: The main objective of this study was to determine the relationship between BMI and β-HCG levels with hyperemesis gravidarum.Materials and Methods: This study was a case control study which compares between BMI and β-Hcg levels of patients with hyperemesis gravidarum and without hyperemesis gravidarum. This study was conducted at Obstetric and Ginecology Department of Medical Faculty of Sam Ratulangi University in Manado. This study was conducted on September - November 2018 and participated by 33 pregnant women with hyperemesis gravidarum and 33 pregnant women without hyperemesis gravidarum which were included in accordance to the inclusion criteria and signed the informed consent to participate in this study.Results: The percentage of patients with Hyperemesis Gravidarum within the age group of 20 -35 years old were 23 patients (69.69%). The highest number of patients without Hyperemesis Gravidarum were [VL1] within age group of 20 - 35 years old as many [VL2] as 28 patients (84.84%). Hyperemesis Gravidarum was found the most in normal BMI group, which was 26 patients (78.78%). The patients without hyperemesis gravidarum were also found in the highest number in the normal BMI group, 21 patients (63.63%). T-test showed that there was no significant difference in BMI of group with postive HEG and negative HEG (p = 0.027). Spearman Correlation Test had been conducted to show relationship between β-hCG levels, and there was a strong correlation between gestational age and β-Hcg levels (r = 0,764 ; p = 0,000), which means β-hGG level increased along with gestational age.Conclusion:There was significant relationship between β-hCG and Hyperemesis Gravidarum. There was also a significant relationship between gestational age and β-hCG Levels which mean the increase of β-hGG level is along with the increase of gestational age. Tere was no significant relationship between BMI and Hyperemesis Gravidarum.]]>
<![CDATA[Roots and Wings: Indonesia´s way to improvements of women´s health care ]]>
<![CDATA[Hans-Gerd Meerpohl]]>
<![CDATA[ Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/mog.V27I32019.90-93
<![CDATA[Indonesia is the world’s fourth most populous nation and the largest economy in Southeast Asia. The World Bank recently classified Indonesia as an emerging middle-income country. Enormous gains have been made in poverty reduction, cutting the poverty rate to more than half since 1999, to 9.8% in 2018.(1) However, based on March 2017 data, approximately 20 % of the entire population remain vulnerable of falling into poverty, as their income hover marginally above the national poverty line.(2) Unique challenges for Indonesia´s health care system reflects the fact that approximately 250 million inhabitants from more than 300 ethnic groups spread over 17.000 islands. Indonesia has set itself an ambitious goal of establishing universal health care by 2019, a move commended by the United Nations as part of the 2030 Sustainable Development Goals.(SDGs) Women´s health care, including women’s empowerment and gender equality, is concerned as an especially important issue because - on a global scale- it is one area in which performance has been seen by many to be slow. (3) While Indonesia has experienced greater success in its efforts to reduce the under five mortality rate (27 per 1.000 live births in 2015), efforts to tackle maternal mortality has been less effective as rates have continued to persist above 125 per 100.000 live births over the past decade (6) Having some of those facts in my mind I started my visit to Indonesia and to Surabaya in October 2018 with the desire to understand in the end the country, the people and their health system challenges a bit better.]]>
<![CDATA[New vesicovaginal fistula formation in a rabbit model ]]>
<![CDATA[Eighty M Kurniawati]]>;
<![CDATA[Tri HS Hadi]]>;
<![CDATA[Nur AR Widiatmoko]]>;
<![CDATA[Widjiati Widjiati]]>;
<![CDATA[Fedik A Rantam]]>;
<![CDATA[Budi Santoso]]>;
<![CDATA[Budi I Santoso]]>;
<![CDATA[Hari Paraton]]>;
<![CDATA[Gatut Hardianto]]>;
<![CDATA[Azami D Azinar]]>;
<![CDATA[Boedi Setiawan]]>
<![CDATA[ Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/mog.V27I32019.114-118
<![CDATA[Objective: To create an animal model of vesicovaginal fistula as a modality to develop therapy.Material and Methods: This study was an preliminary experimental study to create new fistula vesicovaginal formation in a rabbit model. Six female New Zealand white rabbits of Stem Cell Research and Development Center of Universitas Airlangga were used in this study and were divided into 3 groups in which there were 2 rabbits in each group. Vesicovaginal fistula formation was performed through laparotomy surgery. After the abdomen is opened, the Nasogastric tube is inserted vaginally into the anterior vaginal wall. The incision is made on the anterior vaginal wall and the posterior wall of the bladder. The Nasogastric tube that comes out of the vagina is inserted into the bladder incision to maintain the formation of vesicovaginal fistula. Both mucosal walls are sutured and tested to determine if there is any leak. Evaluation the model of vesicovaginal fistula was carried out 3 weeks postoperatively according the group.Result: Four out of six rabbits have formed vesicovaginal fistulas, which are from groups two and three. There are no complications during the treatment period until terminationConclusion: Rabbits have the potential to become experimental animals for the vesicovaginal fistula model. The best time to release a nasogastric tube to maintain a fistula is 2 weeks.]]>
<![CDATA[Length of marriage to pregnancy and the risk of preeclampsia ]]>
<![CDATA[Khusnul Putri Maharani]]>;
<![CDATA[Atika Atika]]>;
<![CDATA[Ernawati Ernawati]]>
<![CDATA[ Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/mog.V27I32019.94-98
<![CDATA[Objective: to analyze the relationship between the length of marriage to pregnancy with the incidence of preeclampsia.Materials and Methods: This study was an observational analytic study with case control approach. Samples were 33 respondents with preeclampsia and 66 respondents with normal pregnancy, all were primigravida with age of 20-35 years old in Dr. M. Soewandhie Hospital, Surabaya, Indonesia, in January-June 2017. Data were taken from medical record.Results: This study found that the length of marriage until pregnancy was 0-4 months with percentage of 39.4% and 77.3% for case and control group respectively. Chi-square test resulted in p = 0.00 and contingency coefficient = 0.366, which meant there was relationship between the length of marriage to pregnancy and the incidence of preeclampsia in primigravida in Dr. M. Soewandhie Hospital Surabaya from January to June 2017 despite being in low level. The value of odd ratio (OR) was 0.191 (95% CI 0.077-0.473), which means there was a risk of protection for the length of marriage to pregnancy <4 months against the incidence of preeclampsia.Conclusion: The shorter the length from early marriage to pregnancy in primigravida, the lower the risk for developing preeclampsia.]]>
<![CDATA[Correlation of CTR1, ERCC-1, and HSP70 expressions with cisplastin response in cervical cancer stage IIB ]]>
<![CDATA[Brahmana Askandar]]>;
<![CDATA[Suhatno Suhatno]]>;
<![CDATA[Juliati Hood]]>
<![CDATA[ Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/mog.V27I32019.119-132
<![CDATA[Objectives: This study aimed to determine the resistance of cisplatin (chemotherapy drugs) at three point areas including expression of CTR1, ERCC1, and HSP70 in cervical cancer patients.Materials and Methods: This research used a cross sectional approach. The population in this study were patients with stage IIB of cervical carcinoma. The study sample were patients with stage IIB of cervical carcinoma according to the FIGO classification, patients received cisplatin chemotherapy treatment (50 mg/m2 4 times), had good kidney and liver function. The independent variables in this study were the expression of CTR1, ERCC1, and HSP70 and the dependent variable of this study was the response to cisplatin therapy in cervical cancer. Primary data was obtained through MRI examination after the administration of cisplatin 50 mg/m2 every week. The parameters of this study included the expression of CTR1, ERCC1 and HSP70. Data obtained were analyzed using Wilcoxon rank test, Spearman test and categorical regression with a significance level of p <0.05.Results: The treatment of cisplatin therapy in cervical cancer patients had no significant correlation between the expression of CTR1 and ERCC1, but in the expression of HSP70 there was a significant negative correlation which means that the higher the expression of HSP70, the worse the response of therapy.Conclusion: This study showed that HSP70 expression can be used as an indicator in treatment of cisplatin therapy in cancer patients through MRI examination.]]>
<![CDATA[Knowledge about sexually transmitted infections does not associate with attitude towards LGBT behavior ]]>
<![CDATA[Munadiah Jannatun Naimah]]>;
<![CDATA[Baksono Winardi]]>;
<![CDATA[Pudji Lestari]]>
<![CDATA[ Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/mog.V27I32019.99-102
<![CDATA[Objective: To analyze the association between knowledge about sexually transmitted infections and attitudes towards LGBT behavior in teenagers at Trimurti High School Surabaya.Materials and Methods: A cross sectional study with a sample of 96 students who were selected by random sampling technique based on the attendance list. The data was collected by using primary data via questionnaires at Trimurti High School students in the academic year of 2017/2018. Data were analyzed using Chi Square test.Results: 56.3% of respondents had sufficient knowledge about sexually transmitted infections, 56.3% of respondents had a positive attitude towards LGBT behavior. Chi Square test in significance level of 0,05 reveal p value equal to 0,582, indicating there is no association between the level of knowledge about sexually transmitted infections with attitudes towards LGBT behavior in teenagers at Trimurti High School Surabaya. Conclusion: There is no association between the level of knowledge about sexually transmitted infections and attitudes towards LGBT behavior in teenagers at Trimurti Surabaya High School.]]>
<![CDATA[Outcome of infants with hydrocephalus findings on Intra-Uterine Ultrasound (USG) examination at Dr. Soetomo Hospital, Surabaya, Indonesia, in 2015-2017 ]]>
<![CDATA[Lourin Nova]]>;
<![CDATA[Mohammad Aldika Akbar]]>;
<![CDATA[Agus Sulistyono]]>;
<![CDATA[Wihasto Suryaningtyas]]>;
<![CDATA[Prastiya Indra Gunawan]]>
<![CDATA[ Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/mog.V27I32019.133-139
<![CDATA[Objectives: to report the outcome of cases with hydrocephalus findings on intra-uterine ultrasound (USG) examinations which happened between January 2015 - December 2017 at Dr. Soetomo Hospital.Case Report: During the period of January 2015 - December 2017, 20 pregnant women were found who performed an ante natal examination and obtained the fetus with hydrocephalus on intra uterine ultrasound examination. At the time of delivery, out of a total of 20 cases, all babies were born alive, but only 12 babies performed shunting operations with VP Shunt. But at the time of follow up the condition of the baby when the search of this case, found only 7 cases with living conditions. This is probably due to non-routine post-action control to ensure shunt conditions and complications that can result from shunt or other conditions. As seen from the growth and development of 7 surviving children, all cases with normal growth conditions were established based on WHO growth curve and developmental obstacles in all cases with evaluation using DDST II.Conclusion: Ultrasound examination is useful for determining the fetal prognosis, but for fetoscopic examination and intra uterine operative action remains controversial. Similarly, to determine the exact termination time and delivery mode. Pre-natal counseling and examination is required in mothers with a history of fetal hydrocephalus in previous pregnancies. With routine control is expected better outcomes in fetal hydrocephalus.]]>
