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Majalah Obstetri dan Ginekologi
Published by Universitas Airlangga
ISSN : 08540381     EISSN : 25981013     DOI : 10.20473/mog.V27I32019.90-93
Core Subject : Health,
Health Professions Medicine & Pharmacology
Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.
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Articles 298 Documents
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Comparison of pain intensity, smooth muscle cells density, and alpha-smooth muscle actin expression in ovarian and peritoneal endometriosis Sutrisno Sutrisno; Muhammad Nooryanto; Shella Widya Gani
Majalah Obstetri dan Ginekologi Vol. 29 No. 3 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V29I32021.108-117

Abstract

HIGHLIGHT1. Pain intensity, smooth muscle cells density, and alpha-SMA expression can be used to analyze the role of smooth muscle in endometriosis.2. Compared to healthy individuals, those with endometriosis have higher pain intensity, smooth muscle cells density, and alpha-SMA expression. 3. Among endometriotic patients, those with peritoneal endometriosis have higher pain intensity, smooth muscle cells density, and alpha-SMA expression than those with ovarian endometriosis.4. The expression of alpha-SMA, smooth muscle density, and pain intensity were found to correlate significantly in endometriosis. ABSTRACTObjectives: to identify the role of smooth muscle through the analysis of smooth muscle cells density, expression of a-SMA, and pain intensity.Materials and Methods: The study design was cross-sectional analytic observational. Study sample consisted of women with ovarian endometrios and women with peritoneal endometriosis who underwent laparoscopy and laparotomy in Dr. Saiful Anwar Hospital and RSIA Melati Hospital, both in Malang, Indonesia, from January until December 2019. There were 16 samples: 8 samples of ovarian endometriosis and 8 samples of peritoneal endometriosis. Smooth muscle cell density was analyzed by comparing the number of smooth muscle cells with the total area of endometriosis tissue in one microscopical field. a-SMA expression was obtained by immunohistochemistry. The degree of pain was determined by filling the part 1 point 1-11 of EHP-30 queistionnaire the day after the procedure. Data were analyzed with Independent T-test and Pearson’s correlation test.Results: Pain intensity, smooth muscle cells density, and a-SMA expression was higher in endometriosis patients compared to healthy individuals. Pain intensity, smooth muscle cells density, and a-SMA expression was lower in the ovarian endometriosis compared to peritoneal endometriosis.Conclusion: There was a significant correlation between the expression of a-SMA, smooth muscle density, and pain intensity in endometriosis.
Association of age at menarche, parity, and hormonal contraceptive use with the histologic type of ovarian cancer Firda Azizah; Pungky Mulawardhana; Willy Sandhika
Majalah Obstetri dan Ginekologi Vol. 29 No. 3 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V29I32021.118-123

Abstract

HIGHLIGHT1. Relationship between age at menarche, parity, and contraceptive use with histologic type of ovarian cancer was analyzed. 2. A number of patients with ovarian cancer were analytically observed with retrospective cross-sectional approach and the histologic types of the cancer were determined.3. Age of menarche, parity, and hormonal contraceptive use was found not to have significant correlation with histologic type of ovarian cancer. ABSTRACTObjectives: This study analyzed the relationship between age at menarche, parity, and contraceptive use with histologic type of ovarian cancer.Materials and Methods: This study used an observational analytic with a retrospective cross-sectional approach. The research samples were 128 patients with ovarian cancer at Dr. Saiful Anwar Hospital, Malang, Indonesia, in 2017-2019. All patients underwent primary staging laparotomy. The histologic types of the ovarian cancer consisted of serous type as many as 45, mucinous 45, endometrioid 10, clear cell 20, and others 4. Data analysis used chi-square test.Results: The p value for the relationship between age of menarche and histologic type of ovarian cancer was p=0.500 (p> 0.05), parity p=0.313, and contraceptive use p=0.824. The distribution of clear cell was more common in multiparous, 40% of endometrioid found in nulliparous, while serous were more common in women with hormonal contraceptive use >5 years, whereas mucinous were more common in those with history of use of <5 years.Conclusion: There was no significant relationship between age of menarche, parity, and hormonal contraceptive use on  histologic type of ovarian cancer.
Back Matter Vol. 29 No. 3 December 2021 Majalah Obstetri & Ginekologi
Majalah Obstetri & Ginekologi Vol. 29 No. 3 (2021): December
Publisher : Universitas Airlangga

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Abstract

Correlation between mother's knowledge and husband's support for the success of the Lactational Amenorrhea Method (LAM) Wahyunnisa Indrarosiana; Ernawati Ernawati; Ivon Diah Wittiarika
Majalah Obstetri dan Ginekologi Vol. 29 No. 3 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V29I32021.91-95

Abstract

HIGHLIGHTS 1. Lactational Amenorrhea Method (LAM) is one of the natural contraception methods of postpartum women.2. Mothers' knowledge and husband's support for LAM contraceptive method was suggested to contribute to its success.3. Research and statistical instruments used found that the success of LAM contraceptive was related to mothers' knowledge, but not related to husband's support. ABSTRACTObjectives: This study aimed to analyze the relationship between mother's knowledge and husband's support for the success of LAM contraception in Brengkok Village, Brondong District, Lamongan Regency, East Java, Indonesia.Materials and Methods: This study was an analytic observational study with a sample of 46 mothers who gave exclusive breastfeeding to their babies who met the inclusion criteria. The research instrument used a questionnaire to determine the level of mother's knowledge and husband's support about exclusive breastfeeding. Spearman Rank Correlation Test was used for data analysis with a significance level of 0.05.Results: More than 50% of the respondents (25 respondents) successfully used the LAM method to prevent pregnancy. Statistical test showed that there was a relationship between mother's knowledge and success of LAM contraception with p value of 0.000, with a correlation coefficient of 0.523. Meanwhile, husband's support was not related to the success of LAM contraception with p value of 0.461 with a correlation coefficient of 0.111.Conclusion: Mother's knowledge is related to the success of LAM contraception, and there is no relationship between husband's support and the success of LAM contraception.
Postpartum contraceptive use among pregnant women who delivered at Cipto Mangunkusumo General Hospital, Jakarta, Indonesia : A descriptive study Junita Indarti; Lucas Christiawan; Dalri Suhartomo; Caroline Caroline; Ditha Loho
Majalah Obstetri dan Ginekologi Vol. 29 No. 3 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V29I32021.124-128

Abstract

HIGHLIGHT1. As maternal mortality rate (MMR) is still high, there should be ways to reduce the rate, one of which is the prevention of conception through contraceptive methods. 2. A descriptive study was conducted to all patients giving birth in a national hospital between 2016 to 2019 covering data on the patients, including age, parity, the origin of referral, and type of contraception.3. Most patients who gave birth in the hospital had postpartum contraception, especially permanent contraception and long-term contraception. ABSTRACTObjectives: The maternal mortality rate in Indonesia is one of the highest in the world at 305 out of 100.000 live birth. One of the best ways to reduce MMR is conception prevention through contraceptive methods. According to 2018 Demographic and Health Survey, Indonesia’s Contraceptive Prevalence Rate was as low as 57%, not even reaching the 2015 Millenium Development Goals target of 65%. We conducted a study on postpartum contraceptive use in Dr. Cipto Mangunkusumo National Central General Hospital (RSCM), Jakarta, Indonesia, to see the use of contraception in RSCM so that it can be an example of how contraception is used in RSCM for patients who give birth here.Materials and Methods: A descriptive study was conducted from all patients giving birth in RSCM from 2016 until 2019, data including patient data, consisting of patient age, parity, the origin of referral, and type of contraception, are input from the medical recordResults: There were 5,596 deliveries, consisting of 3,785 C-sections and 1,811 vaginal deliveries. As many as 5332 (95.3%) of subjects had postpartum contraception, 725 (13.67%) of which received tubectomy, and most of which received long-term contraceptive methods (IUD 4414 (82.78%) and implant 44 (0.82%)). As many as 1.065 subjects were more than 35 years of age, 6.2% of which did not use any postpartum contraception. As many as 984 subjects were RSCM bookcases, 6.9% of which did not use any postpartum contraception.Conclusion: Most patients giving birth in RSCM had postpartum contraception, especially permanent contraception and long-term contraception. The contraception profile in RSCM alone can neither describe nor represent the condition and distribution of contraceptive methods in Indonesia because RSCM is a national referral and medical education center whose cases are relatively more complex.
Front Matter Vol. 29 No. 3 December 2021 Majalah Obstetri & Ginekologi
Majalah Obstetri & Ginekologi Vol. 29 No. 3 (2021): December
Publisher : Universitas Airlangga

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Abstract

Different expression of NF-kB and endometrial implant width in the administration of red fruit (Pandanus conoideus Lam) and leuprolide Raudatul Hikmah; Hendy Hendarto; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 30 No. 1 (2022): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I12022.1-9

Abstract

HIGHLIGHTS 1. Endometriosis treatment remains controversial, whether it should be managed with hormonal modulation and/or surgical removal of the lesion.2. NF-kB becomes potential therapeutic target as it has constitutive activation in peritoneal endometriosis.3. It has been recognized that NF-kB expression decreases when red fruit extract is given.4. Effect of red fruit extract, compared to leuprolide, a widely used treatment for endometriosis, on NF-kB expression was examined.5. NF-kB was significantly lower in endometriotic group receiving red fruit extract than in group receiving leuprolide.   ABSTRACT Objectives: This study aimed to prove the effect of different administration of red fruit (Pandanus conoideus Lam) extract and leuprolide on the expression of NF-kB and endometrial implant width in mouse models of endometriosis. Materials and Methods: This study used completely randomized design with pre-post separated sample. The sample size was 36 female mice (Mus muculus), which were divided into 3 groups randomly. They were given with cyclosporine A, estrogen and endometrial tissue to form endometriosis model. Results: The mean expression of NF-kBin in treatment group receiving leuprolide (4.13 + 0.70) and red fruit (2.70 + 1.08) were significantly lower than that in control group (6.94 + 1.007). Whereas, in treatment group receiving red fruit (2.70 + 1.08), it was significantly lower than in those receiving leuprolide (4.13 + 0.70). Mean endometrial implant width in treatment group receiving leuprolide (13.62 + 3.21) and red fruit (8.93 + 2.74) were significantly lower than that in control group (28.89 + 8.28). Whereas, in treatment group receiving leuprolide (13.62 + 3.21), it was not significantly higher than in those receiving red fruit (8.93 + 2.74). Conclusion: The expression of NF-kB was significantly lower after the administration of red fruit than leuprolide. The width of endometrial implant was not significantly lower after the administration of red fruit than after the administration of leuprolide.
Profile of pregnant women with preeclampsia and its termination method Vebianti Permadi; Aditiawarman Aditiawarman; Pudji Lestari
Majalah Obstetri dan Ginekologi Vol. 30 No. 1 (2022): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I12022.10-16

Abstract

HIGHLIGHTS 1. Pregnancy with preeclampsia in this study was mostly terminated by cesarean section. A small percentage was with vaginal delivery.2. Most preeclamptic mothers gave birth by cesarean section exhibited severe symptoms of preeclampsia, such as severe hypertension, severe proteinuria, and visual impairment.   ABSTRACT Objectives: To determine the symptoms of pregnant women with preeclampsia through the method of pregnancy termination. Materials and Methods: This study used a cross-sectional method for descriptive analysis. The total sample included 75 pregnant women with preeclampsia. The sampling techniques was carried out with purposive sampling. This study used auxiliary data in medical records of preeclampsia mothers who gave birth at Taman Husada Regional Hospital, Bontang, Indonesia, in 2019. Results: The results showed that most preeclampsia mothers delivered by cesarean section (CS). Among mothers who gave birth by cesarean section, there were severe symptoms of preeclampsia, 74.14% had severe hypertension with systolic blood pressure of > 160 mmHg or diastolic blood pressure of > 110 mmHg. Those with severe proteinuria with urine protein > 2g/24 hours or > +2 were 82.76% and 60.35% of those complained visual impairment with blurred vision. Conclusion: These data indicated that most mothers with preeclampsia gave birth by cesarean section and exhibited severe symptoms of preeclampsia.
Maternal and perinatal outcomes of pre-referral magnesium sulfate treatment in severe preeclampsia patients Rizki Amalia Sari; Sulistiawati Sulistiawati; Ernawati Ernawati
Majalah Obstetri dan Ginekologi Vol. 30 No. 1 (2022): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I12022.17-23

Abstract

HIGHLIGHTS 1. Consumption of magnesium sulfate is recommended for prevention against eclampsia. 2. Magnesium sulfate administration to preeclamptic mothers is effective in reducing the risk of eclampsia.3. Pre-referral magnesium sulfate administration and maternal and perinatal outcomes in severe preeclampsia patients was analyzed.4. Magnesium sulfate did reduce eclampsia risk, but not ICU and NICU care rates, maternal mortality, perinatal asphyxia, and perinatal mortality.   ABSTRACT Objectives: This study analyzed the association between pre- referral magnesium sulfate administration and maternal and perinatal outcomes in severe preeclampsia patients. Materials and Methods: This was a retrospective observational analytic study using cross-sectional design. Samples were 132 pregnant women with preeclampsia referred to dr. Saiful Anwar, Hospital Malang, Indonesia in 2019. Data were taken from the patients’ medical records. Maternal outcomes measured in this study were the incidence of eclampsia, ICU care, and maternal mortality, while the perinatal outcomes included the incidence of asphyxia, NICU care, and perinatal mortality. Results: Patients’ history of magnesium sulphate administration significantly associated with the incidence of eclampsia with p-value 0.035 and odds ratio (OR) 2.413, thus consumption of magnesium sulphate could reduce the risk of seizures. However, it did not associate with either maternal ICU care outcomes (p-value 0.087, OR 2.028), or maternal mortality (p-value 0.573). No relationship was found neither between history of magnesium sulphate administration in pregnant women with severe preeclampsia and perinatal outcomes nor with the incidence of asphyxia (p-value 0. 577, OR 0.795), with NICU treatment (p-value 0.205, OR 0.579), and with perinatal mortality (p-value 0.153, OR 3.259). Conclusion: Magnesium sulfate reduced the risk of eclampsia, yet it did not affect either the rate of ICU care, maternal mortality, incidence rate of perinatal asphyxia, the rate of NICU care, or perinatal mortality.
Preeclampsia correlates with maternal and perinatal outcomes in Regional Public Hospital, Madiun, Indonesia Fadhila Anindya Putri Ariyan; Eko Gunawan Sukowati; Widi Fatmawati
Majalah Obstetri dan Ginekologi Vol. 30 No. 1 (2022): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I12022.24-31

Abstract

HIGHLIGHTS 1. Preeclampsia, the high blood pressure during pregnancy, and its complications has significant role in maternal outcomes.2. Correlation between preeclampsia and maternal as well as perinatal outcomes was examined.3. Preeclampsia correlated significantly with delivery process, IUGR, LBW, and preterm birth, but not significantly with antepartum and postpartum hemorrhages, eclampsia, HELLP syndrome, maternal and perinatal mortality, as well as with neonatal asphyxia.   ABSTRACT Objectives: This research aimed to find correlation between preeclampsia and maternal as well as perinatal outcomes in Regional Public Hospital, Madiun, Indonesia, from 1 January 2017 to 30 September 2020. Materials and Methods: An observational analysis was applied in this study with a cross-sectional design. This study used secondary data from medical records of Regional Public Hospital, Madiun, Indonesia, with retrospective sampling and total sampling methods. Samples were 250 preeclamptic mothers with or without severe symptoms. Results: Of 250 preeclamptic mothers, only 216 samples could participate in this study. Maternal outcomes included spontaneous PV delivery (12.22%), SC (87.78%), antepartum hemorrhage (0.45%), postpartum hemorrhage (6.33%), eclampsia (0.45%), HELLP syndrome (0.90%), and maternal mortality (0.45%), while perinatal outcomes covered IUGR (7.69%), LBW (33.94%), preterm birth (12.67%), perinatal mortality (2.71%), and asphyxia neonatorum (13.12%). Conclusion: There was a significant correlation between preeclampsia with or without severe symptoms and maternal outcomes, which was the delivery process, and perinatal outcomes, which were the IUGR, LBW, and preterm birth. However, there was no significant correlation for antepartum hemorrhage, postpartum hemorrhage, eclampsia, HELLP syndrome, maternal mortality (maternal outcomes), perinatal mortality and neonatal asphyxia (perinatal outcomes).

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