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Majalah Obstetri dan Ginekologi
Published by Universitas Airlangga
ISSN : 08540381     EISSN : 25981013     DOI : 10.20473/mog.V27I32019.90-93
Core Subject : Health,
Health Professions Medicine & Pharmacology
Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.
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Articles 298 Documents
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Psychological aspects of precocious puberty child during the COVID-19 pandemic Nurul Ima Suciwiyati; Nur Rochmah; Muhammad Faizi; Fadhil Abiyyu Yofi
Majalah Obstetri & Ginekologi Vol. 30 No. 3 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I32022.139-145

Abstract

HIGHLIGHTS 1. Presents a longitudinal case of a child with Organic Central Precocious Puberty (CPP).2. Focused on psychological aspect during the COVID-19 pandemic.   ABSTRACT Objective: To present a longitudinal case of a child with organic Central Precocious Puberty (CPP) that focused on medical, growth and development, and parent’s psychological aspect during the COVID-19 pandemic. Case Report: A 14-month old girl attended with major complaints of breasts enlargement and menstruation. The Tanner's stage was at A1M3P1 and the vagina showed reddish-brown spots. The patient’s bone age was advanced (3 years and 6 months). USG examination showed a corpus uterine: cervix ratio of 2:1. GnRH stimulation test showed an elevated of FSH/LH and estradiol. MRI showed an extra-axial dense mass that leads to Hypothalamic Hamartoma (HH). The definitive diagnosis of this patient was organic CPP with HH. The patient was managed with GnRH analog. Precocious puberty (PP) becomes a financial and psychosocial burden for parents. The COVID-19 pandemic adds a double burden for the parents. Conclusion: During the COVID-19 pandemic, parents with PP children had a good psychological aspect if the child was comprehensively handled with adequate motivation and psychoeducation.
Inflammatory markers in lean Polycystic Ovary Syndrome subjects are not associated with the spectrum of dyslipidemia Elisia Atnil; Andon Hestiantoro; Oki Riayati; Ririn Rahmala Febri; Naylah Muna
Majalah Obstetri & Ginekologi Vol. 30 No. 2 (2022): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I22022.66-71

Abstract

HIGHLIGHTS 1. Polycystic ovarian syndrome (PCOS) might be a condition of chronic low degree inflammation and dyslipidemia.2. Association between inflammation markers and dyslipidemia in PCOS patients was investigated.3. Dyslipidemia and chronic low degree inflammation were present in lean PCOS patients, but inflammation markers related insignificantly with dyslipidemia.   ABSTRACT Objectives: This study aimed to address the detailed lipid profile in lean woman with PCOS and investigate the relationship between chronic low grade inflammation (using NLR, PLR, and monocyte/HDL ratio) and dyslipidemia (defined as total cholesterol level > 190 mg/dL). Materials and Methods: This study was a cross-sectional study conducted from June – December 2020 at the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, involving 45 women aged 18 – 35 years old, diagnosed as having PCOS with normal BMI (18.5 – 22.9 kg/m2). To compare quantitative variables, data analysis was carried out using the t-test or Mann-Whitney U test as appropriate; whereas, to compare categorical variables, the Chi-square test was used. Results: We found that although the median BMI was within normal limits at 21.48 kg/m2, the mean values of the lipid profiles were found to be either abnormal or borderline, indicating the high possibility of dyslipidemia. No statistically association between NLR, PLR and MHR with dyslipidemia. Conclusion: Dyslipidemia and chronic low-grade inflammation were found in lean PCOS subjects, but there was no significant association between inflammation markers (NLR, PLR and MHR) and dyslipidemia. Further studies should investigate other factors that cause the inflammation.
Increased vulvovaginal candidiasis incidence risk in various gestational ages at a private midwifery practice in Surabaya, Indonesia Regina Martina Cilik; Willy Sandhika; Zakiyatul Faizah
Majalah Obstetri & Ginekologi Vol. 30 No. 2 (2022): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I22022.72-77

Abstract

HIGHLIGHTS 1. Hormonal changes during pregnancy lead to the presence of vulvovaginal candidiasis.2. Increased incidence of vulvovaginal candidiasis in different pregnancy trimesters were analyzed.3. Frequency of vulvovaginal candidiasis tends to increase along with the gestational age.   ABSTRACT Objectives: This study aimed to analyze whether there was an increase in the incidence risk of vulvovaginal candidiasis at various gestational ages. Materials and Methods: A study examined vaginal smears of pregnant women at a private midwifery practice Farida Hadjri, Surabaya, Indonesia. A total sample of 96 patients was taken by the consecutive sampling method, consisting of 32 patients each from the 1st, 2nd, and 3rd trimester of pregnancy.y The smear was examined using Gram stain at Balai Besar Laboratorium Kesehatan Daerah Jawa Timur to detect the presence of fungi elements. Data were analyzed using Chi-square test with 95% confidence interval to investigate whether there was an increased risk of vulvovaginal candidiasis and gestational age. Results: There was an increased risk of vulvovaginal candidiasis and increased gestational age (p < 0.05). This result was related to the hormonal status of pregnant women. An increase in estrogen level during pregnancy leads to an increase in glycogen production by vaginal epithelial cells, which cause the vaginal environment to become more susceptible to fungal growth. Conclusion: There was increased vulvovaginal candidiasis incidence risk along with gestational age. Pregnancy is one of the predisposing factors for candida infection.
Calcium serum concentration among pregnant women in a tertiary hospital and its satellite hospital in Medan, Indonesia Muhammad Agung Khoiri; Sarma N Lumbanraja; Duddy Aldiansyah; M. Fidel Ganis Siregar; Makmur Sitepu; M. Rhiza Tala
Majalah Obstetri & Ginekologi Vol. 30 No. 2 (2022): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I22022.78-83

Abstract

HIGHLIGHTS 1. Serum calcium concentration in pregnant women who took prenatal appointments in the general hospital and its satellite hospitals were evaluated.2. It was found that serum calcium concentration in those pregnant women who made the prenatal appointments were normal.   ABSTRACT Objectives: This study aimed to evaluate serum calcium concentration in pregnant women who made prenatal appointments to Obstetric and Gynecologic Outpatient Clinics at Adam Malik General Hospital, Medan, Indonesia, and its satellite hospitals. Materials and Methods: This study was a descriptive study with a case series approach. The case series of the study included 35 pregnant women in their second or third trimester chosen by consecutive sampling method. Results: The mean calcium serum level of pregnant women in the second and third trimester was 9.12±0.49 mg/dl and 8.97±0.26 mg/dl, respectively. The mean calcium level of pregnant women aged <20, 20-35, and >35 years old were 9.0±0.28 mg/dl, 9.07±0.44 mg/dl, and 8.96±0.06 mg/dl, respectively. Conclusion: This study found that the mean calcium serum level of pregnant women who took prenatal appointments in Haji Adam Malik General Hospital, Medan, Indonesia, was normal.
Updated study of peripartum cardiomyopathy and preeclampsia I Gusti Ngurah Agung Trisnu Kamajaya; Made Bagus Dwi Ariyana
Majalah Obstetri & Ginekologi Vol. 30 No. 2 (2022): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I22022.101-107

Abstract

HIGHLIGHTS 1. Cardiovascular disease that occurs during pregnancy is the peripartum cardiomyopathy (PPCM).2. Literature on the association between preeclampsia (PE) and PPCM was reviewed.3. It was not certain whether PE is the independent risk factor of PPCM or an early predictor of PPCM development.   ABSTRACT Objectives: This paper aims to review the literature related to peripartum cardiomyopathy (PPCM) and preeclampsia (PE) in order to know their frequency and relationship and the current knowledge on their pathophysiology and management. Materials and Methods: The articles reviewed in this study were primary clinical studies published around 2016 and 2021, retrieved using Google Scholar and PUBMED databases. After several evaluations, 14-full-text studies written in English were examined. Results: Overall prevalence of PE in PPCM cases varied, about 9.9% - 44% in the individual studies. The lactation hormone prolactin and placental-derived anti-angiogenic factor soluble Fms-like tyrosine kinase 1 (sFlt-1), which had been known to be able to cause cardiac dysfunction, were elevated in both PE and PPCM. This partly explained the pathophysiology that the incidence of concurrent PE in women diagnosed with PPCM was four times more than that in the general population. Conclusion: Epidemiologic studies showed significant overlap between PE and PPCM patients. However, there were not enough good quality data to fully draw conclusions about the relationship between PE and PPCM, whether PE as the independent risk factor of PPCM or an early predictor of PPCM development.
Cobas® 4800 HPV test is accurate for detecting high risk Human Papillomavirus from urine samples at dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia Indiarto Wityawan; Andrijono; Aria Kekalih
Majalah Obstetri & Ginekologi Vol. 30 No. 3 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I32022.116-121

Abstract

HIGHLIGHTS 1. The presence of Human Papillomavirus (HPV) can be detected using urine samples, as compared to cervical samples, by means of Cobas® 4800 HPV test.2. The concordance between cervical and urine samples for HPV DNA was found as much as 84.72%.3. Urine samples subjected to Cobas® 4800 HPV test is helpful to treat HPV infection.   ABSTRACT Objective: To find the accuracy, sensitivity, specificity, as well as predicted values, both positive and negative, of urine samples using Cobas® 4800 in detecting high risk Human Papillomavirus. Materials and Methods: This study was a cross-sectional study with a total of 72 samples taken from medical records of hrHPV DNA examination with Cobas® 4800 in 2017-2020. Study subjects were called for re-examination of urine samples and cervical samples using Cobas® 4800. Samples with positive hrHPV DNA in the cervix, urine, or both were examined for cervical fluid-based cytology (LBC). Data were analyzed using Chi-square. Results: Overall, 84.72% agreement was detected through specimens of urine and cervical mucus tested of hrHPV DNA with Cobas® 4800. In all samples, a significant rate of concordance detection of hrHPV DNA with Cobas® 4800 was reported (ka = 0.62; 95% IC: 39-84). In this population, in determining the presence of hrHPV DNA in cervical and urine specimens, it was found that the sensitivity, specificity, positive predictive value and negative predictive value were respectively 87.5% (95% IC: 64–97%), 84% (95% IC: 72–91%), 60.9% (95% IC: 40.8–77.8%), and 96 % (95% IC: 86.3–98.9%). Conclusion: The presence of hrHPV infection in the cervix can be determined by detecting hrHPV DNA in the urine. According to these findings, urine samples subjected to the Cobas® 4800 HPV test may be helpful for the clinical treatment of HPV infection.
The role of antihypertensive drugs in patients with preeclampsia and how to prevent it I Gde Sastra Winata; I Wayan Agus Surya Pradnyana; Maria Septiana Parmonang Aroean
Majalah Obstetri & Ginekologi Vol. 30 No. 3 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I32022.146-153

Abstract

HIGHLIGHTS 1. Preeclampsia, or hypertension in pregnancy, remains a serious problem that has negative short and long-term consequences for the mother and the baby.2. The use of antihypertensive medications has its own precautions as it they may harm the fetus.3. Prophylactic measures with minimal or moderate impact may be beneficial for mothers with hypertension in pregnancy.   ABSTRACT Treatment of hypertension in pregnancy, such as preeclampsia (PE), is still a difficult issue with negative short and long-term consequences for both the mother and the baby. Screening for preeclampsia at 11-13 weeks' gestation using a combination of maternal demographic characteristics and medical history with biomarker measurements can identify approximately 75% of women who develop premature preeclampsia with delivery at 37 weeks gestation and 90% of those with early preeclampsia. Preeclampsia has a 10% positive screen rate at 32 weeks. Another important worry on the use of antihypertensive medications during pregnancy is the potential harm to the fetus. Methyldopa, hydralazine, labetalol, and nifedipine are some common antihypertensive medications. Aspirin use is frequently related to a decrease in the prevention of early preeclampsia, but it must be accompanied by medication adherence. Aspirin can be coupled with heparin. Recent investigations on the use of furosemide and nifedipine in preeclampsia have also revealed a new combination. 
Maternal and neonatal outcomes in delivery with diagnosis of antepartum hemorrhage due to placenta previa at a tertiary hospital in Surabaya, Indonesia Sarah Nia Amru; Indra Yuliati; Philia Setiawan
Majalah Obstetri & Ginekologi Vol. 30 No. 3 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I32022.122-127

Abstract

HIGHLIGHTS 1. To provide effective prevention and management of placenta previa, maternal and neonatal outcomes should be identified.2. Among mothers studied, no maternal mortality was found, but most newborns had prematurity and low birthweight.   ABSTRACT Objective: To identify maternal and neonatal outcomes in delivery with diagnosis of antepartum hemorrhage (APH) due to placenta previa. Materials and Methods: This was a descriptive retrospective study with cross-sectional design. Samples were taken using medical records with convenience sampling technique. Deliveries with history of APH due to placenta previa at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, on January 1 until December 31, 2019, were included. Results: In our study, 36 mothers were included. Maternal characteristics included age of 20–35 years in 72.2%, overweight in 50%, referral visits in 69.4%, from out of town (66.7%), bleeding onset at 3rd trimester (97.2%),  primigravida (8.3%), nulliparity (13.9%), 69.4% with history of C-section, and 83.3% no hospital readmissions. Maternal outcomes included 100% mothers diagnosed with complete placenta previa and performed C-section. The mothers were mostly (69.4%) diagnosed with placenta accreta spectrum (PAS). There were 36.1% hysterectomy, 33.3% postpartum hemorrhage, 50% blood transfusions, and zero maternal mortality. Neonatal outcomes included prematurity in 80%, low birth weight (LBW) in 51.5%, while 77.1% and 85.7% of newborns had no asphyxia at 1 and 5 minutes, consecutively. Conclusion: All mothers experienced complete placenta previa, and underwent C-section with most of the mothers were diagnosed with PAS. Less than half of them needed hysterectomy intervention because other patients with focal type PAS were planned for conservative surgery. Moreover, they mostly did not have postpartum hemorrhage with half of them needed blood transfusion. There was zero maternal mortality, with most newborns experienced prematurity, LBW but no significant asphyxia.
Clinical manifestations comparison in hospitalized pregnant and non-pregnant women with Covid-19 at Mataram University Hospital, Mataram, Indonesia Putu Diah Ananda Putri Atmaja; Ario Danianto; Titi Pambudi Karuniawaty
Majalah Obstetri & Ginekologi Vol. 30 No. 2 (2022): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I22022.84-91

Abstract

HIGHLIGHTS 1. Clinical manifestations in pregnant and non-pregnant women with Covid-19 were identified.2. Pregnant women with Covid-19 mostly had asymptomatic clinical manifestations, while non-pregnant women with Covid-19 mostly had symptomatic clinical manifestations.3. Recognition of the clinical manifestations in pregnant women with Covid-19 may help early detection and treatment of pregnant Covid-19 patients.   ABSTRACT Objectives: To know a comparison of clinical manifestations in pregnant and non-pregnant Covid-19 patients who are hospitalized at Mataram University Hospital. Materials and Methods: This study was a descriptive observational study with a cross-sectional approach, using secondary data in the form of medical records. This study uses a total sampling technique, sample selection based on affordable population, inclusion criteria, and exclusion criteria. The data was processed with SPSS 25th version and analyzed with a Chi-square analysis test. Results: In this study, it was found that 145 women confirmed Covid-19 on RT-PCR, 89 of which were pregnant and 56 others weren’t; 85.4% of the included pregnant women were in the 3rd trimester. Clinical manifestations in pregnant women are 73.0% asymptomatic while symptomatic in 60.7% of the non-pregnant women. In symptomatic pregnant women, most common clinical symptoms were nausea, vomiting, cough, and headache; while the most common clinical symptoms in non-pregnant women were cough, anosmia, and headache. Chi-square analysis test showed a significant relationship with p = 0.000 (p < 0.05) in clinical manifestation comparison. Conclusion: There are differences in clinical manifestations in pregnant and non-pregnant women with Covid-19. The most common clinical manifestation in pregnant women was asymptomatic and in non-pregnant women the most common clinical manifestation was symptomatic.  
Impact of E2 and FSH levels on the severity of Stress Urinary Incontinence (SUI) in menopausal women Leny Suardi; Pribakti Budinurdjaja; Wiwit Agung Sri Nurcahyawati; Meitria Syahadatina Noor
Majalah Obstetri & Ginekologi Vol. 30 No. 2 (2022): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I22022.92-100

Abstract

HIGHLIGHTS 1. E2 and FSH levels in menopausal women are thought to have relationship with stress urinary incontinensia (SUI).2. It was found that E2 and FSH levels had no significant relationship with SUI severity in menopausal women.   ABSTRACT Objectives: This study aimed to analyze the relationship between E2 and FSH levels in menopausal women with the severity of Stress Urinary Incontinence (SUI) at Ulin Hospital, Banjarmasin, Indonesia. Materials and Methods: This study used an analytic observational method with cross-sectional design in menopausal women diagnosed with Urinary Incontinence (UI) from October 2020 - March 2021. The independent variables were E2 and FSH levels. The dependent variable was the severity of SUI in menopausal women. The severity of SUI was determined by the Incontinence Severity Index (ISI) scoring. Data were analyzed by Spearman correlation. Results: The subjects who met the criteria were 25 women. The results showed the prevalence rate of SUI was 5.8% with E2 and FSH levels of mild SUI (14.25 pg/mL and 49.70 mIU/mL), moderate (7.91 pg/mL and 54.13 mIU/mL), and severe (9.14 pg/mL) and 70.97 mIU/mL). The number of severity levels of mild SUI was 44%, moderate SUI was 48%, and severe SUI was 8%. Most patients with SUI aged >60 years, multipara, normal body mass index (BMI), duration of menopause <10 years, menarche <15 years, Intrauterine Device (IUD) contraception, and delivered with spontaneous vaginal delivery. There was no significant relationship between E2 levels and the severity of SUI with a p-value of 0.084 and a correlation coefficient of -0.353. There was no significant relationship between FSH level and severity of SUI with a p-value of 0.367 and a correlation coefficient of 0.189. Conclusion: There was no significant relationship between E2 and FSH levels and the severity of SUI in menopausal women. It is necessary to do research on other factors that influence the high severity of SUI in menopausal women.  

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