Dental Journal (Majalah Kedokteran Gigi)
The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.
Articles
964 Documents
Breket titanium (Titanium bracket)
Sianiwati Goenharto;
Achmad Sjafei
Dental Journal (Majalah Kedokteran Gigi) Vol. 38 No. 3 (2005): September 2005
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v38.i3.p120-123
There has been a considerable discussion in the literature about corrosion and sensitivity to the nickel present in stainless steel brackets. Titanium has been heralded as a material totally compatible in the oral environment and superior in structural integrity compared to stainless steel. Many current applications in dentistry and medicine have made titanium an obvious choice for a possible substitute material. Titanium based brackets have shown excellent corrosion resistance and possessed good biocompatibility. Evaluation of titanium brackets for orthodontic therapy showed that titanium brackets were comparable to stainless steel brackets in passive and active configuration. Study about metallographic structure, hardness, bond strength to enamel substrate, etc. showed that titanium brackets exhibited a potential for clinical application. It was concluded that titanium brackets were suitable substitute for stainless steel brackets.
Esthetic rehabilitation of crowded and protruded anterior dentition
Cecilia G. J. lunardhi;
Eric Priyo Prasetyo
Dental Journal (Majalah Kedokteran Gigi) Vol. 42 No. 1 (2009): March 2009
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v42.i1.p46-59
Background: Recent trends put estheticrehabilitationas a demandingtreatmentin order to correct malpositionedanteriordentition. This is enhanced by the patient’s background, especially careers that require prime appearance for the public. Purpose: To describe that even though there are many treatment alternatives and procedures, esthetic rehabilitation on crowded and protruded anterior dentition using endodontic treatment, cast posts and all ceramic crowns, can improve patient’s appearance. Case: This article presents a case report on esthetic rehabilitation of crowded and protruded anterior dentition. Treatment was done due to patient’s refusal in receiving orthodontic treatment. The patient requested esthetic rehabilitation as an expectation for faster and instant esthetic result. Case management: Endodontic treatment was done to the involved dentition prior to the final restoration. Cast posts and all ceramic crowns were used as final restoration to correct the crowded and protruded anterior teeth. Conclusion: Esthetic rehabilitation can be done successfully on crowded and protruded anterior dentition. Instant result could be achieved by this treatment. This is supported by the fact that dentists should be aware of not only choosing the right treatment and materials but also patient’s expectations and conditions.
Pulp tissue inflammation and angiogenesis after pulp capping with transforming growth factor β1
Sri Kunarti
Dental Journal (Majalah Kedokteran Gigi) Vol. 41 No. 2 (2008): June 2008
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v41.i2.p88-90
In Restorative dentistry the opportunity to develop biomemitic approaches has been signalled by the possible use of various biological macromolecules in direct pulp capping reparation. The presence of growth factors in dentin matrix and the putative role indicating odontoblast differentiation during embryogenesis has led to the examination on the effect of endogenous TGF-β1. TGF-β1 is one of the Growth Factors that plays an important role in pulp healing. The application of exogenous TGF-β1 in direct pulp capping treatment should be experimented in fibroblast tissue in-vivo to see the responses of inflammatory cells and development of new blood vessels. The increase in food supplies always occurs in the process of inflammation therefore the development of angiogenesis is required to fulfil the requirement. This in-vivo study done on orthodontic patients indicated for premolar extraction between 10–15 years of age. A class V cavity preparation was created in the buccal aspect 1 mm above gingival margin to pulp exposure. The cavity was slowly irrigated with saline solution and dried using a sterile small cotton pellet. The sterile absorbable collagen membrane was applied and soaked in 5 ml TGF-β1. It was covered by a Teflon pledge to separate from Glass Ionomer Cement restoration. Evaluation was performed on day 7; 14; and 21. All samples were histopathologycally examined and data was statistically analysed using one way ANOVA and Dunnet T3.There were no inflammatory symptoms in clinical examination on both Ca(OH)2 and TGF-β1, but they increased the infiltration of inflammatory cells on histopathological examination. There were no significant differences (p > 0.05) between Ca(OH)2 and TGF-β1 in inflammation cell and significant differences (p < 0.05) in angiogenesis on day 7 and 14. There were no significant differences (p > 0.05) in inflammation cell with in TGF-β1 groups and significant differences (p < 0.05) with in Ca(OH)2 groups on day 7 and 14. It is concluded TGF-β1 functions as direct capping medication has the same inflammatory response as Ca(OH)2, however, TGF-β1 developed angiogenesis earlier than Ca(OH)2.
Ekspresi produk gen laten virus epstein-barr pada karsinoma sel skuamosa rongga mulut (The expressions of latent gene product of epstein-barr virus in oral squamous cell carcinoma)
Theresia Indah Budhy S
Dental Journal (Majalah Kedokteran Gigi) Vol. 38 No. 2 (2005): June 2005
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v38.i2.p84-87
Squamous cell carcinoma (SCC) is a type of cancer often found in oral cavity and the area of head and neck at about 90%. Based on the geographical incidence oral SCC (OSCC) has many types of different emerging. This case probably has connection with ethnic group, habit and social and economical condition. In East Java, the incidence is about 2.64% and it increases every year. The virus is known as one of the main factors that result in this disease. Epstein-Barr virus (EBV) has potential capability of carcinogenesis. EBV is the family of herpesviridae that can infect cell through the linking of CD 21 receptor of the epithel with glycol protein 350/220 of the virus capsule. After primary infection, the virus will form latent-gene in human cell. Periodically, the latent-gene product can disturb proliferation and apoptotic regulator. In Indonesia, the expression of EBV latent geneproduct in the OSCC has not been reported yet. This study wanted to know the expression of EBV latent gene product found in the OSCC. This study found 25 cases of OSCC in which 17 were infected by EBV. Detection of EBV infection could be done by insitu hybridization to identify RNA EBV (EBER). To find the expression of EBV latent gene product, immunohistochemical analysis was done. The conclusion was that the emerging of expression of EBV latent gene product in OSCC were latent membrane protein-1 (LMP-1), EBV nuclear antigen-1 (EBNA-1) and RNA EBV (EBER). They were 28.28%, 25.26% and 46.47%. It was suggested to do the following research on OSCC infected by EBV and the emerging of expression of EBV latent gene product with regulator gene of proliferation and apoptotic in OSCC.
The citotoxicity of calcium hydroxide intracanal dressing by MTT assay
Nanik Zubaidah
Dental Journal (Majalah Kedokteran Gigi) Vol. 40 No. 4 (2007): December 2007
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v40.i4.p157-160
Calcium hydroxide had been used as the intracanal dressing in endodontic treatment due to its high alkaline and high antimicrobial capacity. It also be able to dissolve the necrotic tissue, prevent the root resorbtion and regenerate a new hard tissue. The aim of this study is to identify the concentration of calcium hydroxide that has the lowest citotoxicity. There are 5 groups, each group had 8 samples with different concentration of calcium hydroxide. Group I: 50%, Group II: 55%, Group III: 60%, Group IV: 65% and Group V: 70%. The citotoxicity test by using enzymatic assay of MTT [3-(4.5- dimethylthiazol-2yl) ]-2.5 diphenyl tetrazolium bromide, against fibroblast cell (BHK-21). The result of susceptibility test was showed by the citotoxicity detection of the survive cell of fibroblast that was measured spectrophotometrically using 595 nm beam. The data was analyzed using One-Way ANOVA test with significant difference α = 0.05 and subsequently LSD test. The result showed that in concentration 50%, 55%, 60%, 65%, and 70% calcium hydroxide had low toxicity, but calcium hydroxide 60%, had the lowest toxicity.
Apoptosis of Rattus novergicus gingival fibroblasts caused by silver nano-particles gel exposure
Kharinna Widowati;
Titiek Berniyanti;
Retno Pudji Rahayu
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 3 (2015): September 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v48.i3.p135-138
Background: The use of silver nanoparticle are growing, especially in medical science. It’s used in many concentration. In dentistry, it’s used to decrease halitosis, periodontal diseases, and wound healing. It can affect the viability of the cells, give bad effects to the human’s health and environment if used in a long duration and in certain concentration. Purpose: The purpose of this study was to learn the apoptosis of gingival fibroblasts in Rattus novergicus which is exposed with 15 µg/ml silver nano-particle gel by the expression of caspase-3. Method: This study used 9 male wistar rats and were divided into 3 groups. Sample in group A were cut (hurt) in the oral gingiva and exposed to Ag-Np gel 15 µg/ml for 3 days. After 3 days, they were sacrificed and cut the gingival fibroblasts off 3x4 cm size with scalpel. Samples in group B were cut in the oral gingiva and exposed to Ag-Np Gel 15 µg/ml for 5 days. After 5 days they were sacrificed and the gingival fibroblasts off 3 x 4 cm with a scalpel. Samples in group C were cut in the oral gingiva and exposed to none for 3 days then cut the gingival fibroblasts off 3 x 4 cm size with scalpel. The expressions of caspase-3 in the apoptotic and wound healing process were analyzed by Immunohistochemical test. This data was analyzed by using the t-test method. Result: Mean expression numbers of caspase-3 in the group A=5.67; group B=11.33; and group C (control)=18.67. T-test sign.number of group A and C=0.009; group B & C=0.000. Conclusion: The exposure of 15 µg/ml silver gel nanoparticle to gingival fibroblasts of Rattus novergicus reduces the expressions of caspase-3 in the day-3 and day-5 post exposure. The amounts of cell death through the apoptotic pathway which were analyzed by the expressions of caspase-3 will decrease too.
Prevalence of xerostomia on type 2 diabetes mellitus in Hajj Hospital Surabaya
Kus Harijanti;
Bagus Soebadi;
Irvanda Mulyaningsih
Dental Journal (Majalah Kedokteran Gigi) Vol. 40 No. 3 (2007): September 2007
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v40.i3.p136-139
Diabetes Mellitus (DM) is a chronic disorder of carbohydrate, fat and protein metabolism. A defective or deficient of the insulin secretory, which is translated into impaired carbohydrate (glucose) use, is characteristic feature of DM, as the resultant is hyperglycemia. There is variability among patients, however, morphologic changes are likely found in arteries (atherosclerosis), basement membrane of the blood vessel wall tissues (micro angiopathy), kidneys (diabetic nephropathy), retina (retinopathy), nerves (neuropathy) and other tissues. If it involves salivary glands, the clinical sign is xerostomia. The type 2 of DM is caused by a combination of peripheral resistance to insulin action and an inadequate secretory response of the pancreatic b-cell. Approximately 80% to 90% of patients have type 2 diabetes. The purpose of this study was to determine the prevalence of xerostomia and its relation with level of blood glucose in type 2 DM. The data was taken using cross sectional method on the diabetic patients of Internal Medicine clinic, Hajj Hospital Surabaya from February to March 2006. The result that showed among 50 samples of the type 2 DM, the prevalence of xerostomia were 38 patients (76%). Most of the patients (32 patients = 84%) on bad regulation of DM with level of fasting glucose ≥ 126 mg/dl and level of post prandial glucose ≥ 180 mg/dl. The study showed that bad regulation of type 2 DM could develop complication on salivary glands, with xerostomia as the clinical sign.
Antioxidant activity test on ambonese banana stem sap (Musa parasidiaca var. sapientum)
Hendrik Setia Budi;
Indah Lisatiana Kriswandini;
Aditya Dana Iswara
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 4 (2015): December 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v48.i4.p188-192
Background: Polymorphonuclear cells (PMN) release oxygen free radicals or reactive oxygen species (ROS) during inflammation. As a result, ROS level is higher than antioxidant level in our body during oxidative stress leading to prolong inflammation or continuous tissue damage. Indonesia, on the other hand, is a country with various herbal medicines. For instance, ambonese banana (Musa parasidiaca var. sapientum) is often used as herbal medicine. Ambonese banana, moreover, has flavonoid, polyphenol, tannin, and saponin as antioxidants to reduce free radicals by transferring their hydrogen atom. Medicine used to reduce the impact of free radicals is known as antioxidant. Antioxidant is proved to accelerate wound healing. Purpose: This research aims to analyze the effects of the antioxidant activity of Ambonese banana stem sap extract. Method: Antioxidant activities in this research were examined with 1,1-Diphenyl-2-picryl-hidrazyl (DPPH) method by reacting with stable radical compounds. Spectrophotometry with a wavelength of 517 nm was used to measure absorption results shown in purple. The absorption results then were calculated by IC50 reduction activity. Result: There were significant differences of Ambonese banana stem sap antioxidant activity (p<0.05) at the concentrations of 15%, 30%, and 60 %. All concentrations have greater absorbance scores than IC50 (>50%). Conclusion: Ambonese banana stem sap extract has antioxidant activities.
Study of chemical bond strength of methyl methacrylate (MMA) based bonding agent on type I dentin collagen at various humidity
Adioro Soetojo
Dental Journal (Majalah Kedokteran Gigi) Vol. 40 No. 2 (2007): June 2007
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v40.i2.p89-93
One of the basic agents used in dentin bonding solution is methyl methacrylate (MMA). This bonding agent is widely used in dentistry. It have been proved that the adhesion between dentin bonding agent and collagen fibril is chemically bond; though the chemical bonding contribution is smaller than physical mechanical bond. The purpose of the research was to examined the chemical bonding strength of MMA based dentin bonding on type I dentin collagen at various humidity. Samples of treatment group were put into desiccator with 60%, 70%, 80%, and 90% humidity, while for control groups at room humidity (65%). Chemical bond of pure MMA and MMA mixed with collagen were measured by FTIR. The lower the value of MMA carbonyl, the higher absorbance band speak of chemical bond strength between MMA and collagen. Data was statistically analyzed with One-Way ANOVA at 95% confidence level continued with Tukey-HSD test. The result showed that the highest chemical bond strength was at 65% humidity (p ≤ 0.05). In conclusion, many esther carbonyl MMA molecules reacted with amino collagen at 65% humidity. This can be shown by the lowest peak's value of the MMA carbonyl absorbance at FTIR.
Salivary neutrophils isolation of severe early childhood caries patients with flow cytometry analysis using magnetic beads and CD177 marker
Muhammad Luthfi;
Tuti Kusumaningsih
Dental Journal (Majalah Kedokteran Gigi) Vol. 49 No. 1 (2016): March 2016
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v49.i1.p32-36
Background: Neutrophils are the first line of defense, not only serving as he killer of microbes through phagocytosis process, in which reactive oxygen species (ROS) and anti-microbial peptides were released, but also regulating activation of immune response. CD177 is a tidylinositol glycosylphosphate glycoprotein with a molecular weight of 58- 64-kDa exclusively found on neutrophils, neutrophilic metamyelocytes, and mielosit. CD177 expression, a protein on the cell surface with an average size ranging from 45% to 65%, is only found on subpopulations of neutrophils. Purpose: This study aims to analyze the effects of salivary neutrophil isolation using magnetic beads and CD177 marker on S-ECC patients. Method: The study is an observational analytic research with cross sectional approach using flow cytometry analysis on the S-ECC patients and the caries-free children who were asked to use mouthwash, NaCl 1.5%. For the isolation of neutrophils, magnetic beads labeled with FITC funds and CD177+ marker were used. Result: There were 77.66% of salivary neutrophils expressing CD177+ markers, successfully isolated in the S-ECC patients, while in the caries-free children there were 63.67% of salivary neutrophils. Conclusion: In the S-ECC patients, there were 77.66% of salivary neutrophils expressing CD177markers, successfully isolated, while in the caries-free children there were 63.67% of salivary neutrophils.