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Aktivitas Antidiabetika Kombinasi Fraksi Etil Asetat Buah Pare (Momordica charantia L.) dan Rimpang Zamzani, Irfan; Nugroho, Agung Endro; Widodo, Gunawan Pamudji
Jurnal Farmasi Indonesia Vol 9, No 2 (2017)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v9i2.575

Diabetes Mellitus type 2 can be caused by the resistance of tissue towards insulin accompanied by relative deficiency in insulin secretion. Insulin resistance factor can result from obesity. This research aims to investigate anti- diabetic activity of the compound of FEA of curcuma (Curcuma domestica Val) and bitter melon (Momordica charantia L.). Subjects of this research were 40 albino Wistar rats (Rattus norvegicus) aged 5-8 weeks. The rats were randomly grouped into 8 experimental groups in which each group consisted of'5 rats. The tested animals were divided into 6 groups, KG) metformin 45 mg/Kg BB, P1: FEA curcuma 10 mg/ 200g BB, P2: FEA bitter melon 04 mg/ 200g BB, P3: Compound of FEA curcuma : FEA bitter melon 5 : 0,8 mg/200g BB, P4: Compound of FEA curcuma : FEA bitter melon 10 : 04 mg/200g BB, and P5: Compound of FEA curcuma : FEA bitter melon (20 : 02mg9/200g BB). The animals were inducted with insulin resistance with the giving of HFD-fructose. Result showed that the compound of FEA of curcuma (Curcuma domestica Val) and FEA of bitter melon (Momordica charantia L.) had the activity of lowering blood glucose level: the best anti-diabetic activity was identified in the compound of FEA of curcuma and FEA of bitter melon at the dose of 20: 0,2m9g/200g BB in the rats with HFD- fructose.Diabetes Mellitus type 2 can be caused by the resistance of tissue towards insulin accompanied by relative deficiency in insulin secretion. Insulin resistance factor can result from obesity. This research aims to investigate anti- diabetic activity of the compound of FEA of curcuma (Curcuma domestica Val) and bitter melon (Momordica charantia L.). Subjects of this research were 40 albino Wistar rats (Rattus norvegicus) aged 5-8 weeks. The rats were randomly grouped into 8 experimental groups in which each group consisted of'5 rats. The tested animals were divided into 6 groups, KG) metformin 45 mg/Kg BB, P1: FEA curcuma 10 mg/ 200g BB, P2: FEA bitter melon 04 mg/ 200g BB, P3: Compound of FEA curcuma : FEA bitter melon 5 : 0,8 mg/200g BB, P4: Compound of FEA curcuma : FEA bitter melon 10 : 04 mg/200g BB, and P5: Compound of FEA curcuma : FEA bitter melon (20 : 02mg9/200g BB). The animals were inducted with insulin resistance with the giving of HFD-fructose. Result showed that the compound of FEA of curcuma (Curcuma domestica Val) and FEA of bitter melon (Momordica charantia L.) had the activity of lowering blood glucose level: the best anti-diabetic activity was identified in the compound of FEA of curcuma and FEA of bitter melon at the dose of 20: 0,2m9g/200g BB in the rats with HFD- fructose.Diabetes Mellitus type 2 can be caused by the resistance of tissue towards insulin accompanied by relative deficiency in insulin secretion. Insulin resistance factor can result from obesity. This research aims to investigate anti- diabetic activity of the compound of FEA of curcuma (Curcuma domestica Val) and bitter melon (Momordica charantia L.). Subjects of this research were 40 albino Wistar rats (Rattus norvegicus) aged 5-8 weeks. The rats were randomly grouped into 8 experimental groups in which each group consisted of'5 rats. The tested animals were divided into 6 groups, KG) metformin 45 mg/Kg BB, P1: FEA curcuma 10 mg/ 200g BB, P2: FEA bitter melon 04 mg/ 200g BB, P3: Compound of FEA curcuma : FEA bitter melon 5 : 0,8 mg/200g BB, P4: Compound of FEA curcuma : FEA bitter melon 10 : 04 mg/200g BB, and P5: Compound of FEA curcuma : FEA bitter melon (20 : 02mg9/200g BB). The animals were inducted with insulin resistance with the giving of HFD-fructose. Result showed that the compound of FEA of curcuma (Curcuma domestica Val) and FEA of bitter melon (Momordica charantia L.) had the activity of lowering blood glucose level: the best anti-diabetic activity was identified in the compound of FEA of curcuma and FEA of bitter melon at the dose of 20: 0,2m9g/200g BB in the rats with HFD- fructose.

Aktivitas Antidiabetika Kombinasi Fraksi Etil Asetat Buah Pare (Momordica charantia L.) dan Rimpang Zamzani, Irfan; Nugroho, Agung Endro; Widodo, Gunawan Pamudji
Jurnal Farmasi Indonesia Vol 9, No 2 (2017)
Publisher : Jurnal Farmasi Indonesia

Diabetes Mellitus type 2 can be caused by the resistance of tissue towards insulin accompanied by relative deficiency in insulin secretion. Insulin resistance factor can result from obesity. This research aims to investigate anti- diabetic activity of the compound of FEA of curcuma (Curcuma domestica Val) and bitter melon (Momordica charantia L.). Subjects of this research were 40 albino Wistar rats (Rattus norvegicus) aged 5-8 weeks. The rats were randomly grouped into 8 experimental groups in which each group consisted of'5 rats. The tested animals were divided into 6 groups, KG) metformin 45 mg/Kg BB, P1: FEA curcuma 10 mg/ 200g BB, P2: FEA bitter melon 04 mg/ 200g BB, P3: Compound of FEA curcuma : FEA bitter melon 5 : 0,8 mg/200g BB, P4: Compound of FEA curcuma : FEA bitter melon 10 : 04 mg/200g BB, and P5: Compound of FEA curcuma : FEA bitter melon (20 : 02mg9/200g BB). The animals were inducted with insulin resistance with the giving of HFD-fructose. Result showed that the compound of FEA of curcuma (Curcuma domestica Val) and FEA of bitter melon (Momordica charantia L.) had the activity of lowering blood glucose level: the best anti-diabetic activity was identified in the compound of FEA of curcuma and FEA of bitter melon at the dose of 20: 0,2m9g/200g BB in the rats with HFD- fructose.Diabetes Mellitus type 2 can be caused by the resistance of tissue towards insulin accompanied by relative deficiency in insulin secretion. Insulin resistance factor can result from obesity. This research aims to investigate anti- diabetic activity of the compound of FEA of curcuma (Curcuma domestica Val) and bitter melon (Momordica charantia L.). Subjects of this research were 40 albino Wistar rats (Rattus norvegicus) aged 5-8 weeks. The rats were randomly grouped into 8 experimental groups in which each group consisted of'5 rats. The tested animals were divided into 6 groups, KG) metformin 45 mg/Kg BB, P1: FEA curcuma 10 mg/ 200g BB, P2: FEA bitter melon 04 mg/ 200g BB, P3: Compound of FEA curcuma : FEA bitter melon 5 : 0,8 mg/200g BB, P4: Compound of FEA curcuma : FEA bitter melon 10 : 04 mg/200g BB, and P5: Compound of FEA curcuma : FEA bitter melon (20 : 02mg9/200g BB). The animals were inducted with insulin resistance with the giving of HFD-fructose. Result showed that the compound of FEA of curcuma (Curcuma domestica Val) and FEA of bitter melon (Momordica charantia L.) had the activity of lowering blood glucose level: the best anti-diabetic activity was identified in the compound of FEA of curcuma and FEA of bitter melon at the dose of 20: 0,2m9g/200g BB in the rats with HFD- fructose.Diabetes Mellitus type 2 can be caused by the resistance of tissue towards insulin accompanied by relative deficiency in insulin secretion. Insulin resistance factor can result from obesity. This research aims to investigate anti- diabetic activity of the compound of FEA of curcuma (Curcuma domestica Val) and bitter melon (Momordica charantia L.). Subjects of this research were 40 albino Wistar rats (Rattus norvegicus) aged 5-8 weeks. The rats were randomly grouped into 8 experimental groups in which each group consisted of'5 rats. The tested animals were divided into 6 groups, KG) metformin 45 mg/Kg BB, P1: FEA curcuma 10 mg/ 200g BB, P2: FEA bitter melon 04 mg/ 200g BB, P3: Compound of FEA curcuma : FEA bitter melon 5 : 0,8 mg/200g BB, P4: Compound of FEA curcuma : FEA bitter melon 10 : 04 mg/200g BB, and P5: Compound of FEA curcuma : FEA bitter melon (20 : 02mg9/200g BB). The animals were inducted with insulin resistance with the giving of HFD-fructose. Result showed that the compound of FEA of curcuma (Curcuma domestica Val) and FEA of bitter melon (Momordica charantia L.) had the activity of lowering blood glucose level: the best anti-diabetic activity was identified in the compound of FEA of curcuma and FEA of bitter melon at the dose of 20: 0,2m9g/200g BB in the rats with HFD- fructose.

AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN PELAWAN (Tristaniopsis obovate. Benn) DENGAN METODE PENANGKAPAN RADIKAL BEBAS 2,2’-DIFENIL-1-PIKRILHIDRAZIL Muhammad Farid Al Kadri; Titik Sunarni; Gunawan Pamudji; Irfan Zamzani
JCPS (Journal of Current Pharmaceutical Sciences) Vol 2 No 2 (2019): March 2019
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (873.755 KB)

Radikal bebas merupakan salah satu penyebab terjadinya penyakit degenaratif, sehingga perlu adanya senyawa antioksidan lainnya untuk mengurangi radikal bebas yang dapat menyebabkan kerusakan sel. Tujuan penelitian ini adalah untuk mengetahui aktivitas antioksidan ektrak etanol daun pelawan (Tristaniopsis obovate. Benn) dibandingkan dengan senyawa rutin. Pengujian aktivitas antioksidan ekstrak daun pelawan menggunakan metode penangkapan radikal bebas 2,2’-difenil-1-pikrilhidrazil (DPPH) dan rutin sebagai pembanding. Hasil penelitian menunjukkan bahwa dengan peningkatan konsentrasi ekstrak etanol daun pelawan dan pembanding rutin maka semakin besar pula persen penangkapan radikal bebas DPPH. Hasil aktivitas antioksidan ekstrak etanol daun pelawan dengan IC50 sebesar 14,020 ppm dan standar rutin dengan IC50 sebesar 4,837 ppm. Free radical is one of the causes of degenerative diseases; therefore, it is needed another antioxidant to diminish cell damage. This research aims at investigating antioxidant activity of ethanol extract of Pelawan leaf (Tristaniopsis obovate. Benn) compared to regular substance. The testing of antioxidant activity of Pelawan leaf’s extract utilized the method of capturing 2,2’-diphenyl-1-picrylhydrazyl (DPPH) free radical and regular substance as a standard of comparison. The result shows that the increase of concentration of ethanol extract impacted the high percentage of the capture of DPPH free radical. The result of antioxidant activity of Pelawan leaf’s extract with IC50 was14.020 ppm, and regular standard with IC50 was 4.837 ppm.

Antibacterial activity of Cassia alata stems ethanol extract against Staphylococcus aureus Ahmad Mahdi Mar'ie; Irfan Zamzani; Siti Nashihah
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 10 No 1 (2022): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2022.10.1.5462

Background: Cassia alata leaves, also known as petai cina or gelinggang in Indonesia, are commonly used to treat skin ailments. Objective: The purpose of this study is to test whether stem of C. alata has antibacterial activity against Staphylococcus aureus. Methods: C. alata stems were extracted using an ultrasound-assisted extraction method. For antibacterial activity, disc diffusion was used with extract concentrations of 25%, 50%, 75%, and 100%. Results: The inhibition zones of the ethanol extract of C. alata stems at 25%, 50%, and 75% concentrations were 17.6 mm, 21 mm, and 22.6 mm, respectively, with the highest inhibition zone at 100% concentration at 25 mm. Conclusion: The ethanolic extract of C. alata stems has a strong inhibitory effect on Staphylococcus aureus.

PEMANFAATAN TANAMAN OBAT DAN OBAT TRADISIONAL UNTUK PENGOBATAN HIPERTENSI DI DESA TABING RIMBAH KECAMATAN MANDASTANA Irfan Zamzani; Hayatus Sa adah; Nor Latifah; Islan Nor; Dewi Nurhanifah; Aulia ul Jannah; Basnah; Camelia Ulfah; Denny Tamara
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 7: Desember 2021
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jabdi.v1i7.652

Hipertensi merupakan penyakit yang menyebabkan angka morbiditas yang tinggi, Tekanan darah pada penderita hipertensi dapat diturunkan secara farmakologis dan non farmakologis. Mengingat semakin tingginya insidensi hipertensi, bahaya komplikasi yang ditimbulkan dan efek samping atau dampak farmakologi obat antihipertensi akibat pengobatan jangka panjang, maka perlu dilakukan sosialisasi tentang cara pengendalian hipertensi menggunakan terapi non faramakologis seperti pemanfaatan tanaman obat atau TOGA. TOGA dapat dimanfaatkan sebagai alternatif obat untuk antihipertensi yang tidak memberikan efek samping, murah dan mudah diperoleh karena dapat dibudidayakan sendiri. Tujuan Pengabdian Kepada Masyarakat ini dilakukan untuk sosialisasi dan penanaman tanaman obat yang nantinya dapat dimanfaatkan untuk obat tradisional khususnya pengobatan alternatif untuk hipertensi. Metode pengabdian yang dilakukan terdiri dari dua tahapan, yaitu penyuluhan dan penanaman TOGA. Hasil evaluasi kepuasan peserta menunjukkan kegiatan penyuluhan yang dilakukan berjalan dengan lancar terutama materi yang disampaikan sudah sesuai kebutuhan dan penyampaiannya juga sudah jelas dan mudah dipahami oleh peserta sehingga penyuluhan dinilai bermanfaat dan dapat diaplikasikan dalam kehidupan sehari-hari untuk mencegah hipertensi di lingkungan Desa Tabing Rimbah.

POLA HIDUP SEHAT DAN PEMANFAATAN TOGA DALAM MENGATASI DIABETES MELITUS Nor Latifah; Islan Nor; Hayatus Sa’adah; Irfan Zamzani; Dewi Nurhanifah; Afrida Noor Hani; Akhmad Parhan Naja; Annisa Nurislami; Ari Suprianto
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 6, No 2 (2022): Juni
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v6i2.8265

ABSTRAKDiabetes merupakan penyakit metabolik yang ditandai dengan hiperglikemia akibat kelainan sekresi insulin, kerja insulin, atau keduanya. Hiperglikemia kronis diabetes dikaitkan dengan kerusakan jangka panjang, disfungsi, dan kegagalan berbagai organ. Tingginya kasus kejadian diabetes mellitus memunculkan rasa ingin melakukan agar dapat mengurangi gejala yang ditumbulkan maka perlu adanya pemberian edukasi tentang sosialisasi dan pemanfaatan tanaman obat keluarga dan pola hidup sehat. Tujuan pengabdian masyarakat dilakukan untuk sosialisasi dan penyuluhan mengenai pemanfaatan tanaman obat dan mengenalkan obat tradisional untuk pengobatan diabetes mellitus dan pola hidup sehat dimasa adaptasi baru COVID-19. Metode pengabdian yang dilaksanakan terdiri dari empat tahap yaitu sosialisasi penyuluhan pemanfaatan TOGA, penanaman bibit TOGA, pelayanan kesehatan dan evaluasi. Hasil kegiatan berupa peningkatan pengetahuan, sikap dan prilaku masyarakat dalam menerapkan hidup sehat dan pemanfaatan TOGA dalam pencegahan penyakit diabetes mellitus bagi masyarakat Desa Tabing Rimbah. Kata kunci: sosialisasi; TOGA; diabetes melitus. ABSTRACTDiabetes is a metabolic disease characterized by hyperglycemia due to defects in insulin secretion, insulin action, or both. The Chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of multiple organs. The high incidence of diabetes mellitus raises the desire to do prevention to reduce the arising symptoms. Therefore, it is necessary to provide education and socialization about the use of family medicinal plants (TOGA) and a healthy lifestyle. The purpose of this community service is to socialize and educate the people about the use of medicinal plants and introduce traditional medicines for the treatment of diabetes mellitus and a healthy lifestyle during the new adaptation of COVID-19. The methods to implement this community service consist of four stages, namely the socialization and education on the use TOGA, planting of TOGA seeds, health services, and evaluation. The results of increasing knowledge, attitudes, and behavior of the community in implementing healthy living, and the use of TOGA in the prevention of diabetes mellitus for the people of Tabing Rimbah Village. Keywords: socialization; TOGA; diabetes mellitus.

Potensi Ekstrak Daun Salam (Syzygium polyanthum) dengan Metode UAE Sebagai Antibakteri Terhadap Bakteri Shigella dysenteriae dan Salmonella typhi Siti Norhaliza; Irfan Zamzani; Islan Nor
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 3, No 2 (2022): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v3i2.8294

ABSTRAKTanaman salam (Syzygium polyanthum) dapat dimanfaatkan masyarakat untuk mengobati diare terutama akibat bakteri dan masyarakat sering menggunakan daunnya sebagai pengobatan. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas ekstrak metanol daun salam (Syzygium polyanthum) sebagai antibakteri terhadap bakteri Shigella dysenteriae dan Salmonella typhi serta mengetahui perbedaan daya hambat dengan berbagai konsentrasi ekstrak. Metode yang digunakan adalah difusi cakram dengan konsentrasi ekstrak 25%, 50%, 75% dan 100%. Hasil penelitian pada konsentrasi 100% menunjukkan diameter zona hambat tertinggi dengan nilai rata-rata sebesar 16,63 mm dan 20,36 mm terhadap bakteri Shigella dysenteriae dan Salmonella typhi secara berurutan, sehingga dapat disimpulkan bahwa dengan menggunakan ekstrak daun salam (Syzygium polyanthum) menggunakan metode UAE ini dapat menghambat bakteri Shigella dysenteriae dan Salmonella typhi dengan berbagai seri konsentrasi dan menunjukkan zona hambat yang kuat hingga sangat kuat.Kata kunci : Daun Salam; Shigella dysenteriae; UAE.ABSTRACTThe salam plant (Syzygium polyanthum) can be used by the community to treat diarrhea mainly caused by bacteria and people often use the leaves as a treatment. The purpose of this study was to determine the activity of methanolic extract of salam leaf (Syzygium polyanthum) as an antibacterial against Shigella dysenteriae and Salmonella typhi bacteria and to determine the difference in inhibition with various extract concentrations. The method used was disc diffusion with extract concentrations of 25%, 50%, 75% and 100%. The results of the study at a concentration of 100% showed the diameter of the highest inhibition zone with an average value of 16.63 mm and 20.36 mm against the bacteria Shigella dysenteriae and Salmonella typhi respectively, so it can be concluded that by using extract of salam leaf (Syzygium polyanthum) using the UAE method, it can inhibit Shigella dysenteriae and Salmonella typhi bacteria with various concentration series and show a strong to very strong zone of inhibition.Keywords : Salam leaf; Shigella dysenteriae; UAE.

EVALUASI AKTIVITAS ANTIOKSIDAN DAN PENGHAMBATAN ENZIM ?-GLUCOSIDASE DARI EKSTRAK KERING DAN FRAKSI DAUN JAMBU BOL (Syzygium malaccense): EVALUATION OF ANTIOXIDANT ACTIVITY AND INHIBITION OF ?-GLUCOSIDASE ENZYME FROM DRIED EXTRACT AND FRACTIONS OF JAMBU BOL (Syzygium malaccense) Islan Nor; Irfan Zamzani; Joko Priyanto Wibowo
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.630

Jambu bol (Syzygium malaccense) diberbagai belahan dunia digunakan sebagai pengobatan tradisional untuk mengobati berbagai penyakit dan gejala, termasuk sakit kepala, batuk, peradangan, dan hipertensi. Penyakit degeneratif menimbulkan beberapa penyakit seperti diabetes melitus. Pada tahun 2014 terdapat 422 juta orang dewasa menderita Diabetes Melitus di dunia. Prevalensi meningkat dari 4,7% pada tahun 1980 menjadi 8,5% pada tahun 2014 pada orang dewasa. Angka tertinggi diabetes melitus di Indonesia ditempati oleh DKI Jakarta (3,4%), Kalimantan Timur (3,3%), Yogyakarta (3,2%), dan Sulawesi Utara (3,0%). Antioksidan berperan mencegah penyakit degeneratif yang dikarenakan oleh radikal bebas. Agen penghambat ?-glucosidase dapat menjadi solusi dalam menangani diabetes melitus tipe 2. Tanaman dengan aktivitas antioksidan dan penghambat enzim ?-glucosidase dapat menangani pasien dengan penyakit degeneratif terutama diabetes melitus dengan stres oksidatif, dan menjadi alternatif yang kurang berbahaya dibandingkan obat sintetis. Penelitian ini dilakukan dengan mengekstraksi daun jambu bol dan dikeringkan dengan metode freeze drying, ekstrak difraksinasi dan didapatkan lima fraksi. Ekstrak dan fraksi dilakukan evaluasi terhadap antioksidan dengan metode DPPH dan antihiperglikemik dengan metode penghambatan enzim ?-glucosidase. Hasil dari penelitian ini didapatkan hasil IC50 ekstrak daun jambu bol (Syzygium malaccense) sebesar 57,14 ± 0,42 µg/mL yang termasuk dalam kategori kuat, begitu pula dengan fraksinya yaitu Fr4 dan Fr6 dengan nilai IC50 sebesar 35,52 ± 0,81 µg/mL dan 39,56 ± 1,17 µg/mL, berturut-turut yang tergolong kategori kuat. Begitu pula aktivitas ekstrak dalam menghambat enzim ?-glucosidase dengan persen penghambatan sebesar 83,72 ± 2,06 %. Maka perlu dikembangkan lagi jambu bol (Syzygium malaccense) sebagai agen antioksidan dan agen antihiperglikemia.

PEMANFAATAN DAN PENINGKATAN PRODUKTIVITAS TANAMAN OBAT KELUARGA (TOGA) UNTUK MINUMAN TRADISIONAL HERBAL SEBAGAI IMUNOSTIMULAN Islan Nor; Nor Latifah; Irfan Zamzani; Hayatus Sa’adah; Erlina Fatmawati; Dewi Nurhanifah; Afiatun Rahma
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 7, No 1 (2023): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v7i1.12281

ABSTRAKEdukasi dan pelatihan pembutan minuman obat tradisional merupakan upaya untuk meningkatkan pengetahuan masyarakat dalam memberdayakan potensi tanaman obat keluarga. Edukasi dan pelatihan bertujuan untuk meningkatkan ketrampilan, pengetahuan serta sikap masyarakat dalam menggunakan tanaman obat secara tepat dan rasional. Peranan imunostimulan yang merupakan produk nutrisi/ obat (bahan alam/ sintetik) yang dapat meningkatkan sistem imunitas tubuh menjadi anjuran oleh pihak tenaga kesehatan dan pemerintah kepada masyarakat untuk dikonsumsi secara rutin. Perlu dilakukan pemberian informasi serta wawasan kesehatan untuk meningkatkan pemahaman imunostimulan, pemanfaatan herbal dan keterampilan pembuatan minuman tradisional herbal sebagai imunostimulan. Metode yang digunakan adalah pendekatan persuasif melalui edukasi/ penyuluhan kesehatan serta praktik langsung pengolahan bahan herbal. Pengabdian masyarakat ini melibatkan ibu rumah tangga dan kader kesehatan. Kesimpulan: Kegiatan ini menjadi upaya meningkatkan daya tahan tubuh,dengan pemanfaatan TOGA sebagai bahan untuk pembuatan minuman tradisonal. Kata kunci: tanaman obat keluarga; minuman-herbal; imunostimulan. ABSTRACTEducation and training on the manufacture of traditional medicinal drinks is an effort to increase public knowledge in empowering the potential of family medicinal plants. Education and training aim to improve the skills, knowledge, and attitudes of the community in using medicinal plants appropriately and rationally. The role of immunostimulants, which are nutritional/drug products (natural/synthetic materials) that can improve the body's immune system, is recommended by health workers and the government to the public for regular consumption. It is necessary to provide information/health insight to improve understanding of immunostimulants, use of herbs, and skills in making traditional herbal drinks as immunostimulants. The method used is a persuasive approach through education/health education and direct practice of processing herbal ingredients. This community service involves housewives and health cadres. Conclusion: This activity is an effort to increase endurance, by using TOGA as an ingredient for making traditional drinks. Keywords: family medicinal plants; herbal-drinks; immunostimulants.

Gambaran Pengetahuan Dan Sikap Ibu Dalam Mengobati Diare Menggunakan Tanaman Tradisional di Desa Milangasri Magetan Samuel Budi Harsono; Irfan Zamzani; Liana Djeli Maesaroh
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.2844

In Indonesia, traditional medicine is still widely used by the community. Riskesdas data from 2010 to 2018, shows the use of traditional medicines has increased by 44.3%. The use of these traditional medicines to treat various diseases, one of which is diarrhea. Knowledge about the use of traditional medicinal plants to prevent and treat diarrhea has been passed down from generation to generation. The purpose of this study is to provide an overview of the knowledge and attitudes of mothers in treating diarrhea using traditional plants. This research is a non-experimental quantitative research with descriptive data presentation. Sampling was done by non random sampling technique using purposive sampling method. The research instrument used questionnaires and leaflets as educational media. Data analysis used the Kolmogorov-Smirnov test and the Wilcoxon test. The research sample was mothers aged 21-55 years who were in Milangasri Village, Magetan Regency. The results of the study obtained the number of samples of 95 respondents. The level of knowledge in the pre-test in the good category is 37.89% and the post-test in the good category is 91.58%, while the attitude level for the pre-test in the good category is 51.58% and the post-test in the good category is 89.47%. Kolmogorov test obtained results 0.000 < 0.05 which means the data is not normally distributed and Wilcoxon test results obtained 0.00 < 0.05 which indicates the influence of education on the level of knowledge and attitudes of respondents.

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