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Fitra Perdana
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Penambahan Ekstrak Daun Benalu Kelapa Sawit (Ficus heteropluera Blume) Pada Pembuatan Membran Dan Uji Antibakteri Escherichia coli Yola Suryani; Fitra Perdana; Jufrizal Syahri
Photon: Jurnal Sain dan Kesehatan Vol. 15 No. 1 (2024): Journal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v15i1.6262

Abstract

Palm mistletoe leaves (Ficus heteropluera Blume) are a plant that is effective as an antibacterial medicine. Palm mistletoe leaves contain antibacterial compounds such as flavonoids, tannins, sapoins and phenolics. One alternative to reduce fouling is adding an anti-bifouling agent to the membrane. This research aims to determine the phytochemical test on oil palm mistletoe leaf extract, to see the antibacterial inhibition zone of Escherichia coli and determine the characteristics of thickness and biodegradation, as well as the antibiofouling properties of natural ingredients, namely oil palm mistletoe leaves. The addition of palm mistletoe leaf extract had concentrations of (4:0), (3.96:0.04), and (3.92:0.08) grams. For the antibacterial results obtained by adding a membrane to the additive, namely palm mistletoe leaves, namely variation 1, has an average diameter of 4.73 mm, 4.3 mm and 4.33 mm. The positive control concentration had an average diameter of 38.3 mm. In variation 2 the measurement results do not show the existence of an inhibition zone. The measurement results of the positive control had an average diameter of 38.367 mm. For membrane thickness testing, namely 0.03 mm, 0.06 mm, and 0.06 mm, and the highest biodegradation test was found in the variation of adding 0.08 gram extract, namely 56% and the lowest biodegradation value was in the variation of adding 0.04 gram extract namely 35%.
EXTRACTION, PHYTOCHEMICAL SCREENING, TOTAL PHENOLIC CONTENT, AND ANTIBACTERIAL ACTIVITY OF MISTLETOE ON OIL PALM (Ficus heteropleura Blume) LEAVES Hamiro, Fauzia; Perdana, Fitra; Syahri, Jufrizal
Lantanida Journal Vol 13 No 2 (2025): July-December 2025
Publisher : UIN AR-RANIRY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/lj.v13i2.30892

Abstract

Ficus heteropleura Blume, commonly known as mistletoe on oil palm, is a semi-parasitic plant that grows on oil palm trees. This study aimed to investigate the secondary metabolite profile, determine of total phenolic content, and evaluate antibacterial activity of ethyl acetate extract of F. heteropleura leaves. Extraction was performed using a grade maceration method. Qualitative phytochemical screening was conducted to identify major classes of secondary metabolites, and total phenolic content was quantitatively determined using the Folin–Ciocalteu method with gallic acid as the standard. Ethyl acetate extraction yielded 19.27 g of crude extract. Phytochemical analysis revealed the presence of steroids, flavonoids, saponins, and tannins. The total phenolic content was determined to be 35.730 mg GAE/g. UV-Vis spectrophotometric analysis showed characteristic absorption peaks at 475.0 nm and 432.8 nm, indicating the presence of phenolic pigments with conjugated C=O groups and a peak at 666.3 nm associated with chlorophyll, contributing to the green coloration. FTIR analysis confirmed the presence of functional groups such as O–H, C≡C, C=O, C=C, and C–O. Antibacterial activity demonstrated that the ethyl acetate extract exhibited strong inhibitory effects against Staphylococcus aureus and Escherichia coli, with average inhibition zone diameters ranging from 5 to 10 mm, indicating strong antibacterial activity.
Extraction and total phenolic content from mistletoe on oil palm (Ficus heteropleura Blume) leaves and evaluation of their antibacterial and antioxidant activities. Fhadilla Sahara; Fitra Perdana; Rahmiwati Hilma
Acta Chimica Asiana Vol. 9 No. 1 (2026)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v8i2.247

Abstract

Ficus heteropleura Blume, commonly known as mistletoe, is a semi-parasitic plant frequently found on oil palm plants. This study aimed to evaluate the secondary metabolite content, total phenolic concentration, and the antibacterial and antioxidant activities of the ethanol extract of Ficus heteropleura leaves. Extraction was conducted via grade maceration and total phenolic content was determined using the Folin–Ciocalteu method with gallic acid as the standard. Antibacterial activity was tested using the disc diffusion method against Staphylococcus aureus and Escherichia coli, while antioxidant potential was evaluated through the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. Phytochemical screening confirmed the presence of flavonoids, terpenoids, saponins, tannins, and phenolics with a total phenolic content of 25.500 mg GAE/g. The extract exhibited moderate antibacterial activity with inhibition zones ranging from 7.5 to 10.3 mm. The antioxidant activity was classified as very strong with an IC₅₀ value of 0.67 µg/mL, compared to 0.45 µg/mL for ascorbic acid.
Adsorption of Acacia Bark (Acacia crassicarpa) on Cd(II) Metal in Solution Mukhlis, Mukhlis; Aulia, Fiona; Tamboesai, Emrizal Mahidin; Devi, Silvera; Perdana, Fitra; Fawrin, Heralda
Journal of The Indonesian Society of Integrated Chemistry Vol. 18 No. 1 (2026): Journal of The Indonesian Society of Integrated Chemistry
Publisher : Pendidikan Kimia FKIP Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jisic.v18i1.52993

Abstract

Adsorption of Cd(II) metal from aqueous solution using acacia bark powder as adsorbent was performed in this study. This study aims to determine the efficiency and the best adsorption capacity of Acacia bark powder in Cd(II) adsorption with adsorbent dosage and pH parameters. The method used in this study is Cd adsorption (II) batch. Acacia bark powder was characterized using SEM, FTIR and BET to determine surface morphology, powder functional group, powder surface area, pore volume and pore size. Based on research that has been done the best dosage conditions and PH optimization obtained at 3.5 g, pH 8 and adsorption efficiency reached 98.81% and a capacity of 1.3763 mg/g. It is believed that the Acacia bark powder (Acacia crassicarpa) has a high ability to adsorb Cd(II) metal at dose and pH variations
Asam HidroksiAsam Hidroksisinamat dari Drynaria sparsisora ​​sebagai Agen Anti-Vibrio: Bukti Terintegrasi In Vitro dan In Silicosinamat dari Drynaria sparsisora sebagai Agen Anti-Vibrio: Bukti Terpadu Secara In Vitro dan In Silico Hesti Marliza; Fitra Perdana; Yuli Haryani; Hilwan Yuda Teruna; Rudi Hendra
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 2 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i2.974

Abstract

Drynaria sparsisora is a fern species long utilized in ethnomedicine and recognized as a source of phenolic compounds. This study aims to isolate antibacterial ingredients from D. sparsisora, evaluate their efficacy against Vibrio species, and investigate potential molecular interactions by in silico docking analysis. Dried plant material was extracted with methanol and separated by liquid–liquid partitioning followed by chromatographic purification. Two main compounds were identified and structurally characterized using UV–Vis, FTIR, and ¹H/¹³C NMR spectroscopy. Spectroscopic measurements established the identification of the substances as ferulic acid (1) and caffeic acid (2). In vitro antibacterial activity was investigated against Vibrio alginolyticus, Vibrio parahaemolyticus, and Vibrio cholerae using a broth microdilution method to determine minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Both isolated compounds displayed MIC values of 20 µg/mL and MBC values of 40 µg/mL against all tested strains, leading to an MBC/MIC ratio of 2, confirming bactericidal activity. Although chloramphenicol revealed higher efficacy (MIC 12.5 µg/mL), the separated phenylpropanoids showed consistent and repeatable suppression across all Vibrio species tested. To give mechanistic insight, molecular docking simulations were performed against three bacterial protein targets (PDB IDs: 2ZDQ, 1HNJ, and 3IL7). Both ferulic acid and caffeic acid displayed favorable binding energies and persistent interaction patterns inside the active regions of these proteins, involving hydrogen bonding and hydrophobic interactions. In selected models, docking affinities neared those of chloramphenicol, confirming the likelihood of target engagement. The multi-target binding behavior found suggests possible interference with important bacterial functions, including cell wall function, protein synthesis, and fatty acid production. Overall, the data reveal that D. sparsisora contains hydroxycinnamic acids with considerable bactericidal activity against Vibrio spp., backed by computational evidence of protein interaction. Further investigations are necessary to validate molecular targets and clarify antibacterial processes.
Transfer Teknologi Pengolahan Bunga Telang (Clitoria ternatea) menjadi Teh Celup Herbal di Desa Dayang Suri Kecamatan Bunga Raya Kabupaten Siak Fitra Perdana; Andi Dahliaty; Yuana Nurulita; Heralda Fawrin; Selfi Yanti; Yuli Haryani
Unri Conference Series: Community Engagement Vol 7 (2025): Seminar Nasional Pemberdayaan Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/unricsce.7.507-512

Abstract

Butterfly pea (Clitoria ternatea) is a plant that provides various health benefits due to its pharmacologically active compounds. Nevertheless, the community’s limited knowledge and skills in utilizing and processing butterfly pea into herbal tea bags underline the importance of this community service activity. Processing butterfly pea into herbal tea serves as an effective approach to make its health benefits more accessible for daily use. This program aimed to enhance community knowledge about the health properties of butterfly pea, improve their skills in producing herbal tea bags, and encourage its development as a household-scale product with market potential, given its simple and low-cost processing method. The target beneficiaries were residents of Dayang Suri Village, Bunga Raya Subdistrict, Siak Regency with 55 participants. Program achievements were measured by determining the increased knowledge and skills in processing butterfly pea into herbal tea bags, as well as growing interest in its commercialization. Pre- and post-test results demonstrated a significant improvement in participants’ average scores from 45% to 87%, with a statistically significant paired t-test result (α=0.05).
Co-Authors Andi Dahliaty Aulia, Fiona Emrizal Mahidin Tamboesai Fawrin, Heralda Fhadilla Sahara Hamiro, Fauzia Heralda Fawrin Hesti Marliza Hilwan Yuda Teruna Jufrizal Syahri Jufrizal Syahri Mukhlis Mukhlis Rahmiwati Hilma Rudi Hendra Selfi Yanti Silvera Devi Yola Suryani Yuana Nurulita Yuli Haryani