Article Per Year (5 Year)
p-Index From 2021 - 2026
2.42
P-Index
This Author published in this journals
All Journal Jurnal Riset Kimia Jurnal Pengabdian UntukMu NegeRI Lantanida Journal ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemistry JURNAL PHOTON Molekul: Jurnal Ilmiah Kimia Acta Chimica Asiana Jurnal Pengabdian kepada Masyarakat Nusantara Makara Journal of Science Mestaka: Jurnal Pengabdian Kepada Masyarakat Molekul: Jurnal Ilmiah Kimia Jurnal Kesehatan Masyarakat
Jufrizal Syahri
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, Universitas Muhammadiyah Riau, Pekanbaru 28156, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Environmental Science Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Nursing Physics Public Health Social Sciences Other

Published : 23 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 23 Documents
Search

 1   2   3 
BIOAKTIVITAS EKSTRAK KULIT BATANG TUMBUHAN LANGKA MERANTI LILIN Syahri, Jufrizal; Rullah, Kamal; Siregar, Sri Hilma
Sistem Informasi Vol 3 No 1 (2012): Jurnal Photon
Publisher : Fakultas MIPA dan Kesehatan Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (376.666 KB)

Abstract

Tumbuhan Shorea teysmaniana Dier adalah tumbuhan khas Provinsi Riau yang sudah langka dan dikenal dengan nama Meranti Lilin. Kulit batang tumbuhan ini diekstrak dengan metoda maserasi, sehingga didapatka ekstrak heksan 40,69 g, ekstrak etilasetat 133,22 g, dan ekstrak methanol 386,29 g. Masing-masing ekstrak dilakukan uji antibakteri dengan metoda difusi dan uji anti oksidan dengan metoda DPPH. Uji antibakteri dilakukan terhadap bakteri Escherichia coli, Staphylococcus aureus, Sallmonella typhii, Bacillus subtilis dengan konsentrasi 1%. Ekstrak heksana tidak menunjukkan aktivitas, ekstrak etilasetat memberikan zona bening berturut-turut (mm) 13,2; 12,3; 9,6; 9;9. Ekstrak metanol menunjukkan aktifitas dg membentuk zona bening berturut-turut (mm) 10,6; 10,3; 8,1; 11,0. Berdasarkan aktivitas inilah proses isolasi dilanjutkan dengan menggunakan kromatografi vacum cair sehingga dihasilkan 12 fraksi untuk setiap ekstraknya. Ekstrak aktif dilanjutkan untuk diisolasi sampai senyawa murni, untuk ekstrak etil asetat menghasilkan 2 senyawa murni dengan kode HT1 dan HT2.
PELATIHAN PEMBUATAN PUBLIKASI ILMIAH GURU-GURU SMA N 2 TAMBANG KABUPATEN KAMPAR Jufrizal Syahri; Rahmiwati Hilma; Hasmalina Nasution; Prasetya Prasetya; Rahmadini Syafri; Sri Hilma Siregar; Nurlaili Nurlaili
Jurnal Pengabdian UntukMu NegeRI Vol 2 No 1 (2018): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1821.179 KB) | DOI: 10.37859/jpumri.v2i1.689

Abstract

The writing of scientific writing is one of the efforts to develop the profession of teachers of SMA N 2 Tambang in Kampar regency. This training aims to equip teachers in terms of strategies to develop scientific papers properly in accordance with the guidelines of writing, and equip teachers in the publication procedures of scientific papers in the journal. The training of scientific writing is done by varied lecture method and practice. The lecture method is needed to explain the procedure for the preparation of scientific papers, including how to arrange classroom action research into a scientific paper. Methods of practice are needed to allow the participants to write scientific papers in the form of articles for journals. The training activities of the writing of scientific papers as a whole can be said to be well seen from the achievement of the target of the trainee, the achievement of the training objectives, the achievement of the planned material targets, and the ability of the participants in the mastery of the material. The supporting factors for the implementation of Community Service activities are the availability of experts in SMA N 2 Tambang, the enthusiasm of the participants, the support of the principal of the place of administration, and the supporting funds of the faculty.
PELATIHAN, PEMBIMBINGAN PTK DAN PUBLIKASI ILMIAH GURU-GURU SMA NEGERI 7 PEKANBARU Rahmiwati Hilma; Prasetya Prasetya; Hasmalina Nasution; Rahmadini Syafri; Fitra Perdana; Jufrizal Syahri; Sri Hilma Siregar
Jurnal Pengabdian UntukMu NegeRI Vol 3 No 1 (2019): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (198.408 KB) | DOI: 10.37859/jpumri.v3i1.1124

Abstract

Scientific writing training was one of the efforts to develop the profession of high school teachers N 7 Pekanbaru. The training aims to equip high school teachers of N 7 Pekanbaru in terms of strategizing the scientific papers correctly according to the writing guidelines, and equip the teachers in the scientific writing publication procedures in the journal. The training method is the percentage of resources, discussion and simulation of papers that have been prepared by the trainees. The lecture method is necessary to explain the procedures of scientific writing, including how to arrange class action research into a scientific work. The exercise/practice method is required to give participants a scientific writing for the journal article. This scientific writing training activity in its entirety can be said to be seen from the achievement of the target participants, the achievement of training objectives, the achievement of planned target material, and the ability of participants in Material. The supporting factors in this community service activities are the availability of experts who are imported to the training in SMA N 7 Pekanbaru, participant enthusiasm, the support of the school principal, and the supporting fund of the university . The Output of this activity is expected to have several teacher papers (participants) in the form of journals and proceeding that are ready to be submitted to the relevant journal. Keywords: scientific writings, scientific publications, teacher profession development
Penyuluhan Kesehatan Hidup Sehat Bebas Plastik Di Jalan Melati, RT/RW 04/06, Kelurahan Binawidya, Tampan, Pekanbaru Sri Hilma Siregar; Wirdati Irma; Prasetya Prasetya; Jufrizal Syahri; Rahmiwati Hilma; Fitra Perdana; Trisiwi Kusumaningrum; Yeni Yernita; Pratiwi Gasril; Nurlailli Nasution; Olif Syahbella
Jurnal Pengabdian UntukMu NegeRI Vol 4 No 2 (2020): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v4i2.2140

Abstract

Makanan gorengan merupakan makanan ringan yang sangat digenari oleh masyarakatt Indonesia. Baik dari kalangan atas maupun kalangan kelas bawah.semuanya sangat menyukai makanan ringan gorengan ini. Dikarenakan banyaknya peminat dengan makanan gorengan ini, sehingga menjamurnya penjual gorengan, baik di pngir jalan, di warung-warung ataupun yang pejual gorengan keliling. Masyarakat pada umumnya suka dengan gorengan yang gurih, renyah dan masih panas. Penggunaan pelastik bukan hanya sekedar untuk ditambahkan dalam makanan atau minuman, tetapi juga budaya penggunaan pelastik sebagai kantong pelastik masih sangat tinggi. Setiap manusia selalu menggunakan kantong pelastik ketika mereka pergi berbelanja baik itu ke pasar rakyat, warung, mall ataupun swalayan. Hal ini semakin menambah jumlah limbah pelastik. Kita tahu bahwa pelastik ini sangat susah terurai di tanah, jika hal ini terjadi terus menerus akan merusak ekosistem tanah sehingga meyebabkan kerusakan lingkungan. Hal inilah yang membuat kami untuk melakukan penyuluhan ke masyarakat mengenai efek samping dari penggunaan pelastik yang berlebihan. Pada pengabdian ini kita menjelaskan dan mengajak masyarakat untuk bijak dalam penggunaan pelastik. Pada pengabdian ini kita juga memberikan pemeriksaan kesehatan gratis yaitu golongan darah, tensi dan kolesterol.
Pemberdayaan Ekonomi Dasawisma Rantau Kopar, Rokan Hilir dengan “SaMaKiRi” (Sabun Mahasiswa Kimia UMRI) Rahmadini Syafri; Prasetya; Jufrizal Syahri; Rahmiwati Hilma; Hasmalina Nasution; Sri Hilma Siregar; Fitra Perdana
Jurnal Pengabdian UntukMu NegeRI Vol 6 No 1 (2022): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v6i1.3669

Abstract

Kabupaten Rokan Hilir dikenal dengan kekayaan ragam budaya dan objek pariwisatannya. Salah satu tradisi turun temurun yang kini menjadi primadona wisata Rokan Hilir adalah ritual Upacara Bakar Tongkang yang kini menjadi agenda wisata tahunan Kabupaten Rokan Hilir. Sejak masa pandemi COVID-19 event tahunan ini terkendala pelaksanaannya mengingat akan mengundang banyak turis hadir dan kerumunan massa. Situasi ini memberikan dampak yang signifikan terhadap tatanan kehidupan sosial dan ekonomi masyarakat global, termasuk masyarakat di Desa Rantau Kopar, Kab. Rokan Hilir. Pada kegiatan ini dilakukan pemberdayaan ekonomi berupa penyuluhan dan pelatihan bagi Ibu-ibu Dasawisma Rantau Kopar untuk memproduksi sendiri produk sabun untuk penerapan protokol kesehatan dan peningkatan pendapatan. Kegiatan ini dilakukan secara offline/luring dengan protokol kesehatan yang ketat. Kegiatan terlaksana dengan baik, terlihat dengan antusias peserta akan materi-materi pelatihan, jumlah peserta yang tidak berubah dari awal kegiatan sampai selesai. Dari kegiatan ini dihasilkan produk sabun “SaMaKiRi” yang diproduksi oleh peserta pelatihan dan Tim dari Prodi Kimia UMRI. Diharapkan kegiatan ini dapat berkelanjutan dan menjadi solusi untuk peningkatan ekonomi kreatif di Desa Rantau Kopar, Kabupaten Rokan Hilir.
BIOAKTIVITAS EKSTRAK KULIT BATANG TUMBUHAN LANGKA MERANTI LILIN Jufrizal Syahri; Kamal Rullah; Sri Hilma Siregar
Sistem Informasi Vol 3 No 1 (2012): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v3i1.142

Abstract

Tumbuhan Shorea teysmaniana Dier adalah tumbuhan khas Provinsi Riau yang sudah langka dan dikenal dengan nama Meranti Lilin. Kulit batang tumbuhan ini diekstrak dengan metoda maserasi, sehingga didapatka ekstrak heksan 40,69 g, ekstrak etilasetat 133,22 g, dan ekstrak methanol 386,29 g. Masing-masing ekstrak dilakukan uji antibakteri dengan metoda difusi dan uji anti oksidan dengan metoda DPPH. Uji antibakteri dilakukan terhadap bakteri Escherichia coli, Staphylococcus aureus, Sallmonella typhii, Bacillus subtilis dengan konsentrasi 1%. Ekstrak heksana tidak menunjukkan aktivitas, ekstrak etilasetat memberikan zona bening berturut-turut (mm) 13,2; 12,3; 9,6; 9;9. Ekstrak metanol menunjukkan aktifitas dg membentuk zona bening berturut-turut (mm) 10,6; 10,3; 8,1; 11,0. Berdasarkan aktivitas inilah proses isolasi dilanjutkan dengan menggunakan kromatografi vacum cair sehingga dihasilkan 12 fraksi untuk setiap ekstraknya. Ekstrak aktif dilanjutkan untuk diisolasi sampai senyawa murni, untuk ekstrak etil asetat menghasilkan 2 senyawa murni dengan kode HT1 dan HT2.
Synthesis and Docking Study of 2–Aryl-4,5-diphenyl-1H-imidazole Derivatives as Lead Compounds for Antimalarial Agent Ika Septiana; Bambang Purwono; Chairil Anwar; Beta Achromi Nurohmah; Jufrizal Syahri
Indonesian Journal of Chemistry Vol 22, No 1 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.67777

Abstract

Series of 2-aryl-4,5-diphenyl-1H-imidazole derivatives of 2-(4-hydroxy-3-methoxyphenyl)-4,5-diphenyl-1H-imidazole (1), 2-(4,5-dimethoxyphenyl)-4,5-diphenyl-1H-imidazole (2) and 2-(4-methoxyphenyl)-4,5-diphenyl-1H-imidazole (3) were produced and evaluated for their in vitro antimalarial activities against the chloroquine-sensitive Plasmodium falciparum 3D7 strain. A molecular docking study was also carried out against the crystal protein of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) (PDB ID: 1J3I.pdb) to predict the interaction between the compounds and protein. The physicochemical and pharmacokinetic parameters were computationally performed to predict the parameters of the absorption, distribution, metabolism, excretion, and toxicity (ADMET). Imidazoles were synthesized from aryl aldehyde derivatives with benzyl and ammonium acetate in glacial acetic acid using microwave-assisted-organic synthesis. Compounds 1, 2, and 3 were produced in 64.33, 50.56, and 70.55% yields, respectively. The IC50 of compounds 1, 2, and 3 against chloroquine-sensitive Plasmodium falciparum 3D7 strain was found to be 1.14, 5.28, and 2.42 µM, respectively. The molecular docking study agreed with the in vitro data by showing the lowest CDOCKER energy for compound 1 (-47.48 kcal/mol), followed by 3 (-43.79 kcal/mol) and 2 (-41.47 kcal/mol). The physicochemical and pharmacokinetic parameters showed that imidazoles 1, 2, and 3 obeyed Lipinski rules of five to propose as lead compounds for the antimalarial agents.
Design of New 2,4-Substituted Furo [3,2-B] Indole Derivatives as Anticancer Compounds Using Quantitative Structure-Activity Relationship (QSAR) and Molecular Docking Jufrizal Syahri; Nurul Hidayah; Rahmiwati Hilma; Beta Achromi Nurohmah; Emmy Yuanita
Molekul Vol 15, No 1 (2020)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (346.15 KB) | DOI: 10.20884/1.jm.2020.15.1.582

Abstract

This study aimed to propose new indole derivatives as anticancer through Quantitative Structure-Activity Relationship (QSAR) and molecular docking method. The best predicted anticancer activity of indole derivatives was recommended based on the QSAR equation. A data set consist of 18 indole derivatives from literature with anticancer activity against the A498 cell line was used to generate a QSAR model equation. The data set was divided randomly into training (14) and test (4) set compounds. The structure of indole compound was optimized first using AM1 semi-empirical methods, and the descriptors involved were analyzed using Multiple Linear Regression (MLR). The best QSAR equation obtained was Log IC50 = 65.596 (qC2) + 366.764 (qC6) – 92.742 (qC11) + 503.297 (HOMO) – 492.550 (LUMO) – 76.966. Based on the QSAR model, varying electron-withdrawing groups in C2 and C6 atom, as well as adding electron-donating groups in C11 were proposed could increase the anticancer activity of the indole derivatives. The QSAR analysis showed that compound 15 has the best predicted anticancer activity, supported by molecular docking results that showed hydrogen bond interaction with essential amino acids to build anticancer activity such as MET769, THR830, and THR766 residues.
Design of Trolox Compounds as Antioxidant and Their Analysis Using Quantitative Structure Activity Relationship Hasmalina Nasution; Nur Enizan; Nurlaili Nurlaili; Jufrizal Syahri
Acta Chimica Asiana Vol. 3 No. 2 (2020)
Publisher : Chemistry Education Program, the University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v3i2.40

Abstract

Antioxidant compound can inhibit the oxidation of lipids and other biomolecules. The role of antioxidants is very important in neutralizing and destroying free radicals that can cause the damage to cells in the body. This research was carried out to design trolox derivate compounds as antioxidants using the QSAR method. The semi empirical AM1(Austin Model 1)method was used to generate the QSAR model. The statistical analysis result using multiple linier regression methods revealed thet antioxidant activity was influenced by the descriptors of qC1, qC4, qO7, qC13 and qO18. The QSAR equation model obtained was log IC50 = 0.821 + 7.067 (qC1) + 2.585 (qC4) + 4.812 (qO7) – 5.363 (qC13) – 0.887 (qO18) with the best predicted IC50 value was 4.699 µM. Keywords: Antioxidants, QSAR, semi empirical AM1, trolox
Bio-insecticide’s Extract of Scented Root (Polygala paniculata) in Controlling the Mosquito Aedes aegypti (L.) Wahyuni, Denai; Sari, Nila Puspita; Jasril, Jasril; Syahri, Jufrizal
Makara Journal of Science Vol. 26, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Controlling Aedes aegypti mosquitoes with chemical insecticides causes resistance on humans, environmental residues, and contaminates food and water. Polygala paniculata is a potential alternative to insecticides in controlling Ae. aegypti. This study aimed to determine the effect of the Insecticide Score of P. paniculata extracts on the mortality of Ae. aegypti mosquitoes based on KT50. A total of 20 mosquitoes for each concentration were used to examine the effectiveness of 10%, 15%, 20%, and 25% concentration of P. paniculata extracts compared to a positive and a negative control with four replications. The results showed that P. paniculata extracts had an effect on Aeaegypti mosquito mortality. There were significant differences in mortality rate between concentrations (Kruskal-Wallis test, p = 0.001). Spearman Correlation test gave a p-value of 0.008 < 0.05. Similarly, there was a weak but significant correlation between plant extract concentration and mortality (Spearman correlation: r = +0.312, p = 0.008). The 10% and 15% concentrations had KT50with Insecticide Scores of 1 and 2, respectively, implying that both had no knockdown effect. A 20% concentration had a KT50 with an Insecticide Score of 3, indicating a weak knockdown effect, whereas a 25% concentration had KT50with an Insecticide Score of 5, signifying a quick knockdown effect. These results show that a 25% concentration has a quick knockdown time on Ae. aegypti mosquitoes. Therefore, extract P. paniculata extract at a concentration of 25% has a potential for use as a bio-insecticide in controlling Ae. aegypti mosquitoes.
Co-Authors Adel Zamri Adel Zamri Bambang Purwono Beta Achromi Nurohmah Beta Achromi Nurohmah Chairil Anwar Denai Wahyuni Denai Wahyuni Emmy Yuanita Emmy Yuanita Eti Norhaslinda Fitra Perdana Hamiro, Fauzia Hasmalina Nasution Hendra, Rudi Ika Septiana Jasril Jasril Kamal Rullah Lazulva Lazulva, Lazulva Lisa Utami Maria Ulfa Mifthahul Jannah Nasution, Annio Indah Lestari nasution, Nurlaili Netti Gustina Nur Enizan Nurlaili Nurlaili Nurlaili Nurlaili Nurlailli Nasution Nurul Hidayah Olif Syahbella Prasetya Prasetya Prasetya Prasetya, Prasetya Putri, Rahmayani Indah Rahayu, Anggi Putri Rahmadini Syafri Rahmiwati Hilma Ramadhanti, Aulia Rizki Retno Hidayati Rudi Hendra Saprizal Hadisaputra Sari, Meidita Kemala Sari, Nila Puspita Siregar, Sri Hilma Siregar, srihilma Sri Hilma Siregar Sudirman Sudirman Suma Rahmani Harahap Tri Dharmayani, Ni Komang Trisiwi Kusuma Ningrum Wirdati Irma Wulan Sari, Wulan Yeni Yernita Yuana Nurulita Yuana Nurulita Yuharmen Yuharmen Yuharmen, Yuharmen Yum Eryanti Yum Eryanti Yuni Fatisa `Nasution, Hasmalina