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All Journal Journal of Food and Pharmaceutical Science Pharmascience Jurnal Ilmu Kefarmasian Indonesia JURNAL FARMASIMED (JFM) Sasambo Journal of Pharmacy Journal of Health Science Jurnal Kesehatan Terapan Journal of Food and Pharmaceutical Sciences Jurnal Kesehatan dan Kedokteran
ERISKA AGUSTIN
Universitas Kader Bangsa
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Standarisasi Ekstrak Kunyit Kuning (Curcuma domestica Val.) Di Desa Tanjung Batu Ogan Ilir Sumatera Selatan Hardiyanti, Trirahmi; Agustin, Eriska; Azzahra, Nia; Purnama, Purnama; Arrajib, Rahmad
JURNAL KESEHATAN TERAPAN Vol 9 No 2 (2022): Jurnal Kesehatan Terapan
Publisher : LPPM Universitas Kader Bangsa Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54816/jk.v9i2.540

Abstract

Penyimpanan kunyit kuning sebagai produk terstandar patut diperhatikan dan dicermati. Jika penanganan dan pengolahannya tidak benar maka mutu produk yang dihasilkan kurang berkhasiat. Standardisasi juga diperlukan agar dapat diperoleh bahan baku yang seragam yang pada akhirnya menjamin efek farmakologi tanaman tersebut. Tujuan penelitian ini untuk mengetahui standarisasi ekstrak kunyit kuning (Curcuma domestica Val.) di Desa Tanjung Batu Kabupaten Ogan Ilir Sumatera Selatan. Jenis penelitian menggunakan metode atau percobaan secara in vitro. Penelitian ini dilakukan di Laboratorium Universitas Kader Bangsa dan Laboratorium STIK Siti Kodijah Palembang yang berlangsung pada tanggal 1 Juli – 27 Juli 2020. Prosedur penelitian ini yaitu pengambilan sampel, pengolahan sampel, ekstraksi, uji fitokimia, uji flavonoid, uji tanin, uji saponin, uji alkaloid, uji stroid, dan standarisasi ekstrak parameter spesifik dan non spesifik. Hasil penelitian ini adalah hasil penentuan susut pengeringan estrak kunyit kuning sebesar 0,8726%, hasil penentuan kadar air ekstrak kunyit kuning sebesar 10%, hasil penentuan total bakteri sebanyak 19,20,28 dan penentuan total kapang sebanyak 38,103,114, hasil kadar senyawa yang larut dalam air sebanyak 4,5988% dan kadar senyawa yang larut dalam etanol sebanyak 1,6085%. Kata Kunci: Standarisasi, Ekstrak, Kunyit Kuning, Uji Parameter Spesifik dan Nonspesifik
Formulation and Evaluation of Anti-Dandruff Hair Mask from Lime Peel Extract (Citrus aurantifolia): Antibacterial Activity, Stability, and Safety Assessment Maharani, Andini Putri; Eriska Agustin; Dani Prasetyo
Jurnal Kesehatan dan Kedokteran Vol. 5 No. 1 (2026): Februari: Jurnal Kesehatan dan Kedokteran
Publisher : Asosiasi Dosen Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56127/jukeke.v5i1.2528

Abstract

Dandruff is a common scalp condition caused by Staphylococcus aureus, leading to itching, irritation, and reduced self-confidence. Natural alternatives, such as lime peel (Citrus aurantifolia), which contains antibacterial compounds like flavonoids and saponins, show potential as an effective anti-dandruff agent. Objective: This study aimed to formulate a hair mask using lime peel extract as an anti-dandruff agent and evaluate its physical quality, safety, and antibacterial activity. Methods: A quantitative experimental approach was used, preparing three formulations with 5%, 10%, and 15% lime peel extract. Evaluations included organoleptic, homogeneity, pH, spreadability, stability, irritation, and antibacterial activity tests against Staphylococcus aureus. Results: Formulations F0, F1, and F2 remained stable for 28 days, while F3 showed phase separation from days 21 to 28. All formulations had pH values within the safe range (4.5–6.5). Spreadability was acceptable, and irritation tests revealed that only F3 caused irritation. F3 showed the largest inhibition zone in antibacterial tests, indicating the highest antibacterial efficacy. Implications: This study suggests that higher concentrations of lime peel extract enhance antibacterial efficacy but may compromise stability and cause irritation. Further optimization is needed to improve safety and stability while maintaining effectiveness. Originality: This research contributes original insights into the use of lime peel extract for anti-dandruff treatments, offering a natural alternative to synthetic agents. The study provides valuable data for developing safer and more effective cosmetic formulations.
The utilization of red dragon fruit peel extract (Hylocereus polyrhizus) in nanoemulsion as an antioxidant Agustin, Eriska; Zahara, Ega
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1614

Abstract

The red dragon fruit plant (Hylocereus polyrhizus) contains bioactive substances, one of which functions as an antioxidant from anthocyanin and betacyanin. The Dragon Fruit Peel (DFP) has not been widely used by the community in the health sector, and it is only becomes waste. The preparation of nanoemulsion aims to increase the low antioxidant activity of dragon fruit peels. The preparation of DFP nanoemulsion using 8% Tween 80 as emulsifier, 1% oleic acid, and 2% transcutol, with variations in extract concentrations of 1% and 2%. The globule size is reduced to nanoemulsion using a sonicator bath for 60 minutes. The testing of antioxidant activity using the DPPH method. The results of the organoleptic test showed that the DFP extract nanoemulsion had a transparent yellow color with a globule size and Polidispersity Index (PI) of 165±5.54 nm (PI=0.2±0.03) and 115±3.46 nm (PI=0.3±0.02) at an extract concentration of 1 % and 2%. The globule morphology using TEM shows a spherical shape. The results of the pH test showed a range of 4.5-5.3. In testing the antioxidant activity, the DFP extract nanoemulsion showed an increase in IC50 values at 1% and 2% extract concentrations, namely 85.39±4.69 and 64.46±3.45, compared to the extract without formula (pure extract), namely 167.34±8.98. The DFP nanoemulsion preparations produced globule sizes in the nano range, and antioxidant activity testing showed an increase in the IC50 value of 2 concentrations compared to conventional extracts (p<0.05).
Co-Authors Agustin, Rani Felisia Agustina, Maulia Arrajib, Rahmad Arsa, Arvianida Nafilah Dani Prasetyo Deny Puryani Garnadi Jafar, Garnadi Hardiyanti, Trirahmi Kameliani, Desti Maharani, Andini Putri Martavinus, Whilly Muchtar, Muni’ah Nia Azzahra Purnama Purnama Sari, Gita Deslia Soyata, Amelia Zahara, Ega