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GAMBARAN TINGKAT PENGETAHUAN PASIEN RAWAT JALAN UMUM TENTANG PENGGUNAAN AMOKSISILIN DI PUSKESMAS DONO KABUPATEN TULUNGAGUNG Djembor Sugeng Walujo; Indah Sri Hartini; Yogi Bhakti Marhenta; Wika Atmaja; Krisogonus Ephrino Seran; Hariyani Hariyani; Fitria Wahyuning Wulan; Aditha Nur Azizah
JURNAL PHARMA BHAKTA Vol 6 No 1 (2026): Mei (2026)
Publisher : FACULTY OF PHARMACY, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/jpb.v6i1.170

Abstract

Background: Irrational use of antibiotics, including amoxicillin, contributes to the increase in bacterial resistance and the risk of adverse drug reactions. Adequate patient knowledge is a key factor in promoting appropriate antibiotic use. Objective: To describe the level of knowledge among general outpatients regarding the use of amoxicillin at Dono Public Health Center, Tulungagung Regency. Methods: This study used a descriptive quantitative design with sampling involving 85 respondents who had previously received an amoxicillin prescription. Data were collected using a structured questionnaire consisting of 12 items covering nine knowledge parameters: drug classification, administration rules, dosage, adherence to schedule, appropriate indications, duration of use, legal access, side effects, and common misconceptions. Results: The results showed that 52.94% of respondents had a moderate level of knowledge, 36.47% had a good level of knowledge, and 10.59% had a poor level of knowledge. The highest knowledge score was found in the classification parameter (98.82%), while the lowest scores were in side effects (48.24%) and common misconceptions (49.41%). Conclusion: Patients generally demonstrated adequate knowledge of the basic aspects of amoxicillin use; however, gaps remain in understanding the risks of resistance, side effects, and appropriate indications. Strengthening education and implementing continuous interventions are essential to encourage rational antibiotic use.
Pengaruh Terapi Atorvastatin terhadap Kadar Glukosa Darah pada Pasien Stroke Iskemik dengan Diabetes Melitus yang Dirawat di Rumah Sakit Dwi Evi Diyan Sari; Erni Anika Sari; Faizatul Fitria; Hariyani Hariyani; Krisogonus Ephriono Seran; Shofiatul Fajriyah; Yogi Bhakti Marhenta; Alissya Okta Nanda Agustina
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1481

Abstract

Background: The use of atorvastatin in patients with stroke as a primary preventive therapy may be associated with an increased risk of elevated blood glucose levels. This study aimed to evaluate the effect of atorvastatin on changes in blood glucose levels in patients with ischemic stroke. Methods: An analytical observational study with a retrospective design was conducted among 28 hospitalized patients with ischemic stroke at Bhayangkara Hospital, Kediri City, from March to April 2024. Inclusion criteria comprised patients aged >15 years, with a history of diabetes mellitus, receiving atorvastatin therapy, and having available blood glucose data before and three days after treatment initiation. Data were analyzed using the Shapiro–Wilk test to assess normality and the paired sample t-test to evaluate changes in blood glucose levels. Results: A total of 64,29% of patients experienced an increase in blood glucose levels; however, statistical analysis demonstrated no significant difference between blood glucose levels before and after atorvastatin administration (231.64 ± 99.039 vs 231.50 ± 61.425 mg/dL; Δ = −0.14 mg/dL; p= 0.993). Conclusion: Atorvastatin therapy was not associated with statistically significant changes in random blood glucose levels. However, the high proportion of patients with increased blood glucose warrants further prospective investigation.
Analisis Faktor Kepatuhan Minum Obat Antituberkulosis Pasien Rawat Jalan Pada Layanan Kesehatan Primer : Studi Cross-sectional Di Puskesmas Ngasem Kabupaten Kediri Eko Yudha Prasetyo; Dyah Ayu Kusumaratni; Hariyani Hariyani; Kumala Sari Poespita Dewi Wahyuni; Dwi Evi Dian Sari
Jurnal Ilmiah JOPHUS : Journal Of Pharmacy UMUS Vol. 8 No. 1 (2026): Agustus
Publisher : Program Studi Farmasi, Universitas Muhadi Setiabudi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46772/jophus.v8i1.1953

Abstract

Pengobatan TB melibatkan banyak obat dan durasi terapi yang panjang. Keberhasilan pengobatan sangat dipengaruhi oleh kepatuhan pasien dalam mengonsumsi Obat Anti Tuberkulosis secara teratur. Penelitian ini bertujuan mengetahui tingkat kepatuhan minum Obat Anti Tuberkulosis serta menganalisis faktor-faktor yang mempengaruhinya pada penderita tuberkulosis di Puskesmas Ngasem Kabupaten Kediri. Penelitian menggunakan desain kuantitatif dengan metode survei analitik dan pendekatan prospektif pada Februari–April 2026. Sampel penelitian berjumlah 40 pasien yang dipilih menggunakan teknik total sampling. Tingkat kepatuhan diukur menggunakan metode pill count, sedangkan faktor-faktor yang mempengaruhi kepatuhan diidentifikasi melalui kuesioner yang telah diuji validitas dan reliabilitasnya. Analisis data menggunakan uji Fisher’s Exact Test. Hasil penelitian menunjukkan bahwa 92,5% responden termasuk kategori patuh. Pengetahuan, sikap, efek samping obat, dukungan tenaga kesehatan, dan dukungan keluarga berhubungan signifikan dengan kepatuhan minum obat, sedangkan akses fasilitas kesehatan tidak menunjukkan hubungan yang signifikan. Disimpulkan bahwa peningkatan edukasi, konseling, dan dukungan keluarga serta tenaga kesehatan perlu dipertahankan untuk meningkatkan keberhasilan pengobatan tuberkulosis.