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All Journal The Journal of Experimental Life Sciences (JELS) The Journal of Pure and Applied Chemistry Research GERVASI: Jurnal Pengabdian kepada Masyarakat
Dolly Irnawati Neno
Institut Pendidikan Soe
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Social Sciences Other

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The Effect of Rice Bran Cereals on Total Cholesterol, Malondialdehyde (MDA) Levels and Histopathology Description of Aortic Organ on Mice Model of Hypercholesterolemia Dolly Irnawati Neno; Chanif Mahdi; Sasangka Prasetyawan
The Journal of Pure and Applied Chemistry Research Vol 7, No 3 (2018): Edition September-December 2018
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1070.652 KB) | DOI: 10.21776/ub.jpacr.2018.007.003.429

Abstract

Rice bran cereals could be used as the alternative treatment on hypercholesterolemia condition. Tocopherol as an antioxidant and dietary fiber as cellulose, hemicellulose, and lignin which contained in rice bran cereals have the potential to decrease total cholesteroland malondialdehyde levels. The aims of this study are to determine the role of rice bran cereals to decrease total cholesterol, malondialdehyde levels and improve the histopathologyof the aortic organ due to hypercholesterolemia. This study used rats (Rattus Norvegicus) as animals model which were divided into 5 groups: control group (healthy rats), hypercholesterolemia group (sick rat) and 3 therapy groups with variation dose respectively 270, 540 and 810 mg/kg body weight. Data analysis for total cholesterol and malondialdehyde levels used one-way ANOVA with α = 0.05 with Tukey test as a follow-up test. The results of statistical analysis proved that rice bran cereals with a dose of 810 mg/kg body weight effect for the changes of total cholesterol and malondialdehyde levels which are 21.72% and 50.88%, respectively. In addition, results showed that rice bran cereals therapy could significantly influence (p = 0.05) decrease of total cholesterol, malondialdehyde levels and improve the histopathology of an aortic organ in hypercholesterolemic rats.
Dietary Rice Bran Plays A Significant Role in the Hepatoprotective Effect in Hypercholesterolemic Rats Antula, Yulianti; Neno, Dolly Irnawati; Srihardyastutie, Arie; Mahdi, Chanif
The Journal of Experimental Life Science Vol. 9 No. 2 (2019)
Publisher : Graduate School, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1016.513 KB) | DOI: 10.21776/ub.jels.2019.009.02.08

Abstract

Cholesterol is obtained through biosynthesis and diet. When a level of cholesterol is above the normal level, this condition caused hypercholesterolemia. Long-term administration of synthetic chemical drugs can cause liver damage. Therefore, alternative natural medication is needed. One of the alternatives that can be used is the rice bran (RB), which contains antioxidant and crude fiber. This study is aimed at finding out the potential utilization of RB on total cholesterol level, liver enzyme as aspartate aminotransferase (AST) and alanine aminotransferase (ALT), malondialdehyde (MDA), and the changes in liver tissue. This study uses five groups of rats: the negative control group, positive control group, and three therapy groups with the dosage of 270 mg kg-1, 540 mg kg-1, and 810 mg kg-1 of body weight. This study shows that therapy using RB can significantly decrease the cholesterol level, AST, ALT, and MDA (p<0.01). The total cholesterol level is 21%, AST and ALT activities can be reduced to 54% and 64%, the level of MDA reduced to 79% and can repair the liver tissue. This study shows that RB can be effectively used as hepatoprotective in rats with hypercholesterolemia. Keywords: AST and ALT, Hypercholesterolemia, Rice Bran, Total Cholesterol Level.
HAPPY ARTS AND ENGLISH TIME: IMPLEMENTASI BELAJAR SENI MENGGAMBAR DAN MEWARNAI, MENARI DAN SPELLING BEE Sonya Veningsih Cheryanti Benu; Alse O. Sabat; Dolly I. Neno; Marthen Ch. Toto
GERVASI: Jurnal Pengabdian kepada Masyarakat Vol. 10 No. 1 (2026): GERVASI: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM IKIP PGRI Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31571/gervasi.v10i1.10033

Abstract

Kegiatan pengabdian kepada masyarakat ini dilatarbelakangi oleh kebutuhan anak-anak usia dini untuk memperoleh stimulasi yang menyenangkan, edukatif, dan terintegrasi dalam pengembangan keterampilan seni dan bahasa. TK Kristen Bethania Soe sebagai mitra menunjukkan keterbatasan dalam pelaksanaan pembelajaran kreatif berbasis seni dan bahasa asing, khususnya Bahasa Inggris. Tujuan kegiatan ini adalah untuk meningkatkan kemampuan anak dalam menggambar dan mewarnai, menari dan berekspresi, serta mengenal kosakata Bahasa Inggris melalui kegiatan Happy Arts and English Time. Metode yang digunakan adalah pelatihan langsung berbasis praktik (simulasi) dan pendekatan bermain sambil belajar (play-based learning) yang dikombinasikan dengan pendampingan. Hasil kegiatan menunjukkan adanya peningkatan signifikan dalam tiga aspek keterampilan anak: kemampuan menggambar dan mewarnai meningkat dari 51,7% menjadi 89,6%; kemampuan menari dan ekspresi gerak meningkat dari 45,2% menjadi 86,2%; serta kemampuan dalam pengucapan kosakata Bahasa Inggris meningkat dari 38,0% menjadi 78,5%. Kegiatan ini terbukti efektif sebagai solusi konkret dalam memperkaya pengalaman belajar anak usia dini secara menyenangkan dan bermakna.
Co-Authors Alse Ona Sabat Antula, Yulianti Arie Srihardyastutie Chanif Mahdi Chanif Mahdi Marthen Ch. Toto Sasangka Prasetyawan Sonya Veningsih Cheryanti Benu