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All Journal Jurnal Pengabdian Masyarakat AbdiMas Aptisi Transactions on Technopreneurship (ATT) Media Gizi Kesmas Archives Pharmacia Journal of World Future Medicine, Health and Nursing
Utami, Tyas Putri
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Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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PENINGKATAN KAPASITAS PENGETAHUAN GIZI DAN KETERAMPILAN PERAWATAN LUKA PADA CALON DOKTER CILIK DI SEKOLAH DASAR NEGERI KEDAUNG BARAT 1, TANGERANG Angkasa, Dudung; Mulyana, Budi; Utami, Tyas Putri; Julianti, Putri Firna; Maulana, Handika Rahmat; Lestari, Gina; Amanda, Virgita; Widyawati, Risti Shalsa
Jurnal Pengabdian Masyarakat AbdiMas Vol 10, No 03 (2024): Jurnal Pengabdian Masyarakat Abdimas
Publisher : Universitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/abd.v10i3.7420

Abstract

Usaha Kesehatan Sekolah perlu terus ditingkatan salah satunya dengan memberikan dukungan pelatihan pada calon dokter cilik (dokcil). Pengabdian masyarakat ini bertujuan untuk mengenalkan pilar gizi seimbang dan penanganan luka bagi calon dokcil. Sebanyak 25 calon dokcil terlibat pada kegiatan ini. Calon dokcil terlihat sangat antusias dengan materi yang disampaikan. Tanya jawab muncul dari peserta saat diskusi tentang materi. Walau secara statistik tidak diamati peningkatan bermakna pada pengetauan tentang pilar gizi seimbang, terlihat perbedaan bermakna pada perawatan luka. Kegiatan terdokumentasi dengan baik pada social media @giselprogram dan berita online.
Biosintesis dan uji Antioksidan Nanopartikel Emas Menggunakan Kuersetin Pertiwi, Ratih Dyah; Utami, Tyas Putri; Michelle, Michelle
Archives Pharmacia Vol 6, No 2 (2024): ARCHIVES PHARMACIA
Publisher : Lembaga Penerbitan Universitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/ap.v6i2.8237

Abstract

Sintesis nanopartikel emas dapat dilakukan dengan metode fisika dan metode kimia, namun kedua metode itu menimbulkan limbah berbahaya yang tidak ramah lingkungan, dan mahal, sehingga sintesis nano partikel emas pada penelitian ini dilakukan dengan metode green synthesis karena metode ini ramah lingkungan, dapat diproduksi ulang, relatif terjangkau dan sederhana. Penelitian ini untuk mengetahui kemampuan kuerseti dalam pembuatan sediaan nanopartikel emas, karakteristik, dan aktivitas antioksidan pada sediaan nanopartikel emas yang dihasilkan. Larutan HAuCl4 0,002M disintesis menggunakan kuersetin. Larutan ini dilihat kestabilannya dengan mengamati panjang gelombang selama 8 minggu menggunakan alat spektrofotometer UV-Vis. Larutan nanopartikel emas terbaik dikarakterisasi menggunakan particle size analyzer (PSA) untuk mengetahui Z-average, indeks polidispersitas, dan potensial zetanya. Pengujian aktivitas antioksidan sediaan nanopartikel emas dilakukan menggunakan metode DPPH (2,2-difenil-1- pikrilhidrazil). Uji panjang gelombang maksimum menunjukkan hanya sediaan nanopartikel emas dengan penambahan gom arab dan 3 mL larutan kuersetin 2 mM (F4) yang masuk ke dalam rentang 500-600 nm. Hasi uji kestabilan dan karakterisasi menunjukkan sediaan nanopartikel emas dengan penambahan gom Arab dan 3 mL larutan kuersetin 2 mM memiliki kestabilan terbaik dengan Z-average 116,7 nm, indeks polidispersitas 0,293, dan potensial zeta -12,2 mV. Sediaan nanopartikel emas ini mempunyai kemampuan sebagai antioksidan karena nilai IC50 yang didapatkan sebesar 82,80 ppm.
Isolasi dan Uji Aktivitas Antimikroba Kapang Endofit dari Daun dan Batang Tanaman Jambu Bol (Syzygium malaccense) Terhadap Staphylococcus epidermidis, Escherichia coli dan Candida albicans Putri, Silpiyani; Abna, Inherni Marti; Utami, Tyas Putri
Archives Pharmacia Vol 6, No 1 (2024): ARCHIVES PHARMACIA
Publisher : Lembaga Penerbitan Universitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/ap.v6i1.7602

Abstract

Kapang endofit merupakan mikroba yang hidup pada jaringan tanaman dan tidak membahayakan inangnya. Kapang endofit dapat menghasilkan suatu senyawa bioaktif yang dapat digunakan sebagai senyawa antimikroba, antioksidan, antidiabetik dan antikanker. Tanaman Jambu Bol merupakan salah satu tanaman yang memiliki komponen bioaktif yang banyak digunakan sebagai obat tradisional untuk berbagai penyakit. Penelitian ini dilakukan dengan tujuan untuk mendapatkan isolat kapang endofit dari daun dan batang tanaman jambu bol dan mengetahui aktivitasnya sebagai antimikroba terhadap Staphylococcus epidermidis, Escherichia coli dan Candida albicans. Sebanyak 6 isolat yang menunjukkan potensi antimikroba difermentasi secara goyang pada suhu kamar selama 5 hari dengan kecepatan agitasi 150 rpm. Produk metabolit sekunder kemudian diuji aktivitas antimikrobanya dengan metoda difusi agar (Kirby-Bauer) cara sumuran. Hasil uji aktivitas antimikroba yang diperoleh yaitu Isolat Db2-Pt dapat menghambat Escherichia coli dan Candida albicans. Isolat Dc1-Pt dapat menghambat Staphylococcus epidermidis dan Escherichia coli. Isolat Dc2-Pt dapat menghambat Candida albicans. Isolat Bb1-Pt dapat menghambat Staphylococcus epidermidis. Isolat Bc1-Pt dapat menghambat Escherichia coli. Isolat Bb2P-Pt dapat menghambat Staphylococcus epidermidis dan Candida albicans. Kapang endofit yang dihasilkan dari tanaman jambu bol memiliki aktivitas antimikroba terhadap Staphylococcus epidermidis, Escherichia coli dan Candida albicans dengan kekuatan daya antimikroba sedang dengan diameter zona hambat antara 5 mm sampai 10 mm.
The Impact of the Digital Revolution on Health Research: A Bibliometric Review Judijanto, Loso; Anggo, Sulasmi; Utami, Tyas Putri; Anurogo, Dito; Ningrum, Dedah
Journal of World Future Medicine, Health and Nursing Vol. 2 No. 1 (2024)
Publisher : Yayasan Pendidikan Islam Daarut Thufulah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/health.v2i1.704

Abstract

The digital revolution has had a significant impact on health research. The digital revolution in health refers to the fundamental transformation in the utilization of digital technology to improve aspects of health and medical services. This study aims to evaluate the impact of digital revolution changes on health research with a focus on bibliometric analysis. Another objective was to identify research trends, collaboration patterns, and changes in research methodologies associated with digital technology. The research method involved a bibliometric analysis of the number of health publications related to digital terms such as big data, machine learning, and telemedicine over a period of time. Bibliometric data, such as the number of publications, collaboration between researchers, research topics, and method development, were analyzed quantitatively. The results showed a significant increase in digital health-related publications, as well as cross-disciplinary collaboration and the use of technologies such as big data, machine learning, and image analysis have become dominant trends in research methodologies. The study concluded that the digital revolution has changed the landscape of health research, broadened the scope of research, and accelerated innovations in diagnosis, treatment, and health management. Thus, understanding the impact of this digital revolution is important for health researchers and stakeholders in health policy development. This bibliometric study provides valuable insights into the evolution and implications of the impact of the digital revolution in health research, providing a foundation for further development in this domain.
PENGARUH PELARUT TERHADAP KADAR TOTAL FENOL DAN FLAVONOID DAN AKTIVITAS ANTIOKSIDAN EKSTRAK TANAMAN SARANG SEMUT (Myrmecodia erinaceae Becc.) Rahayu, M.Farm., Apt., Dr. Sri Teguh; Pratiwi, Anisa Aulia; Harizal, Harizal; Utami, Tyas Putri
Archives Pharmacia Vol 7, No 1 (2025): ARCHIVES PHARMACIA
Publisher : Lembaga Penerbitan Universitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/ap.v7i1.9110

Abstract

Tanaman sarang semut (Myrmecodia erinaceae Becc.) merupakan tanaman herbal asli Papua yang diketahui mengandung fenol, flavonoid dan tanin. Penelitian ini bertujuan menguji total fenol, total flavanoid dan aktivitas antioksidan senyawa ekstrak etanol 80%, fraksi air, fraksi etil asetat, fraksi n- butanol, fraksi n- heksana tanaman sarang semut yang berasal dari Wamena Timika Papua. Tanaman sarang semut (Myrmecodia erinaceae Becc.) diekstraksi secara maserasi menggunakan pelarut etanol 80% kemudian difraksi menggunakan etil asetat, n-heksan dan n-butanol. Hasil ekstrak dan fraksi kemudian diuji kandungan total fenol, kandungan total flavanoid dan aktivitas antioksidan. Hasil pengujian menunjukan hasil total fenol pada ekstrak etanol 80%, fraksi air, fraksi etil asetat, fraksi n-butanol, fraksi n-heksan yaitu berturut – turut sebesar 809,27 ± 17,52 mg GAE/g, 704,79 ± 8,07 mg GAE/g, 726,24 ± 35,76 mg GAE/g, 586,68 ± 33,70 mg GAE/g, 254,49 ± 36,97 mg GAE/g. Pengujian terhadap kandungan total flavanoid dengan menggunakan pereaksi AlCl3. Hasil pengujian menunjukan hasil total flavanoid pada ekstrak etanol 80%, fraksi air, fraksi etil asetat, fraksi n-butanol, fraksi n-heksan yaitu sebesar 109,28 ± 2,53 mg QE/g, 93,36 ± 6,81 mg QE/g, 68,22 ± 1,32 mg QE/g, 78,83 ± 4,16 mg QE/g, 16,04 ± 0,25 mg QE/g. Pengujian aktivitas antioksidan dengan metode DPPH dengan pembanding vitamin C. Aktivitas antioksidan diperoleh IC50 ekstrak etanol 80%, fraksi air, fraksi etil asetat, fraksi n- butanol, fraksi n- heksana dan vitamin C berturut-turut sebesar 6,589 ppm, 14,109 ppm, 14,947 ppm, 10,742 ppm, 66,412 ppm dan 14,932 ppm. Berdasarkan hasil IC50, ekstrak etanol 80% tanaman sarang semut menunjukkan aktivitas antioksidan sangat kuat
Gold Nanoparticle Synthesis Using Quercetin: Innovation in Biopreneur Pertiwi, Ratih Dyah; Fitria, Pika Ayu; Utami, Tyas Putri; Pamungkas, Rian Adi; Pradana, Reinaldo; Chamroonsawasdi, Kanittha
Aptisi Transactions On Technopreneurship (ATT) Vol 7 No 1 (2025): March
Publisher : Pandawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34306/att.v7i1.405

Abstract

Biosynthesis offers an environmentally friendly approach for manufacturing nanoparticles, with flavonoids such as quercetin showing potential as reducing agents. This study aimed to synthesize gold nanoparticles (AuNPs) from HAuCl4 using quercetin as a reducing agent. The synthesis process was monitored using UV-Vis spectrophotometry, and the particle size and stability of the nanoparticles were characterized using a Particle Size Analyzer (PSA). The synthesized AuNPs exhibited a color change from light yellow to deep purple, with a peak absorbance between 500 600 nm. The average particle size was found to be 116.7 nm, with a zeta potential of -12.2 mV, and a polydispersity index of 0.293. The inhibitory activity of the AuNPs was assessed by their effect on the tyrosinase enzyme, yielding an IC50 value of 970 μg/mL. These results suggest that gold nanoparticles synthesized using quercetin are stable and exhibit potential inhibitory activity against tyrosinase. The study concludes that this green synthesis method has the potential for further development in drug delivery systems, providing an innovative approach in biopreneurship.
Peran Insulin-like Growth Factor-1 dan Adiponektin dalam Hubungan antara Asupan, Aktifitas Fisik, dan Sindrom Metabolik pada Anak dan Remaja Melayuaustronesia: Protokol Resensi Sistematis Angkasa, Dudung; Utami, Tyas Putri; Mulyana, Budi; Salleh, Razali Mohamed; Hasan, Hosni; Appukuty, Mahenderan
Media Gizi Kesmas Vol 13 No 2 (2024): MEDIA GIZI KESMAS (DECEMBER 2024)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v13i2.2024.850-859

Abstract

Background: Risk factors of metabolic syndromes develop in childhood and tacks across life, which may lead them to a higher risk of getting cardiovascular diseases and premature deaths. A healthy diet and being physically active are supposed to modify the risk of metabolic syndromes (MetS). However, those observations primarily work in adult samples and the biological mechanisms that link that behavioral factor and MetS in children and adolescents still need to be explored. Asian people are more likely to get MetS than their white counterparts, but study in Malay-Austronesia children is minimal.   Objectives: This study aims to comprehensively review and appraise studies that elucidate biological factors (insulin-like growth factor-1 and adiponectin) that possibly mediate the relationship between those risk factors and MetS in Malay-Austronesia children. Methods: The search will be performed in PubMed, Scopus, Web of Science, Google Scholar, and local databases Garuda (Garba Rujukan Digital, Indonesian) and Mycite (Malaysian citation index). All prospective cohort studies that examine the association of one of the behavioral factors (dietary intakes OR physical activity) AND one of the biological factors (Insulin-like growth factor OR adiponectin) with MetS or its components in healthy children with the exposures start from the age of 1 and 12 years of age and outcomes begin from 1 year and two months until the age of 18 years old are eligible. Only literature in English and local languages from inception to 31 December 2023 that match eligibility criteria will be included. National Institute of Health tool for observational studies will be used to assess the quality of included studies. This work was registered to PROSPERO CRD42023471481.   Results: The findings may shed light on how the predefined biological factors mediate those behavioural factors on MetS in children. The findings will also be published in a peer-reviewed journal. Conclusion: This review utilizes relevant databases to optimize the searching of eligible studies. Eligible studies will be extracted by more (four) researchers who work independently with a predefined data extraction template. There are possibility some studies report significant finding on IGF-1 binding protein instead of total IGF-1 or its molar ratio will challenge the statistical analysis.
Co-Authors Abna, Inherni Marti Amanda, Virgita Appukuty, Mahenderan Budi Mulyana, Budi Chamroonsawasdi, Kanittha Dito Anurogo, Dito Dudung Angkasa Fitria, Pika Ayu Gina Lestari, Gina Harizal Harizal Hasan, Hosni Judijanto, Loso Julianti, Putri Firna Maulana, Handika Rahmat Michelle, Michelle ningrum, dedah - Pertiwi, Ratih Dyah Pradana, Reinaldo Pratiwi, Anisa Aulia Putri, Silpiyani Rahayu, M.Farm., Apt., Dr. Sri Teguh Rian Adi Pamungkas Salleh, Razali Mohamed SULASMI ANGGO Widyawati, Risti Shalsa