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All Journal Mejuajua Journal of Dental and Biosciences
Eka Prasasti Nur Rachmani
Universitas Jenderal Soedirman
Humanities Dentistry Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Other

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The activity of saga leaf (Abrus precatorius) ethanol extract fractions on biofilm degradation of Fusobacterium nucleatum Satya Maharani br. Simatupang; Fanni Kusuma Djati; Meylida Ichsyani; Eka Prasasti Nur Rachmani; Maulina Triani
Journal of Dental and Biosciences Vol 3 No 02 (2026): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2026.3.02.14766

Abstract

Periodontitis is a chronic inflammatory disease causing permanent destruction of periodontal tissues. Fusobacterium nucleatum is a key bacterium involved in periodontitis biofilm formation. Biofilm degradation is crucial for periodontitis treatment. This study aimed to investigate the antibiofilm activity of ethanol extract fractions from Abrus precatorius leaves against F. Nucleatum. An in vitro experimental study was conducted using nine treatment groups, consisting of three fractions (n-hexane, ethyl acetate, and residual) at three concentrations (3.125, 6.25, and 12.5 mg/mL). Chlorhexidine gluconate 0.2% and metronidazole served as positive controls, while 1% DMSO was used as a negative control. Biofilm degradation was assessed using microtiter plate assay with crystal violet 1% staining and Microplate Reader at 600 nm. Data analysis employed one-way and two-way ANOVA, followed by post-hoc LSD and Tukey HSD tests. Results showed that all fractions at various concentrations effectively degraded biofilm (p≤0,05) compared to the negative control, except for the residual fraction at 3,125 mg/mL. Two-way ANOVA revealed significant differences between concentrations and fractions. The n-hexane fraction at 3.125 mg/mL demonstrated the highest biofilm degradation efficacy, comparable to chlorhexidine gluconate 0.2%. This study concludes that Abrus precatorius leaf ethanol extract fractions exhibit antibiofilm activity against F. Nucleatum.
Pemberdayaan Mustahik Melalui Kebun Sayur Dan Ayam Kampung Berbasis Zakat Produktif Di Desa Melung Elly Tugiyanti; Sri Wahyu Handayani; Dyah Susanti; Eka Prasasti Nur Rachmani; Normalita Destyarini
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 6 No. 1 (2026): Agustus 2026
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuaj.abdimas.v6i1.421

Abstract

Productive zakat can support household food access by financing food-production assets and sustained mentoring, but operational outputs should not be interpreted as nutrition impacts. This community service evaluated an intervention integrating home gardens and village chickens for mustahik households in Melung Village, Banyumas Regency. Sixty-two households were screened using economic vulnerability, food conditions, household-space readiness, and willingness to participate; 41 were selected. Evaluation used distribution records, field observation, brief interviews, activity documentation, and four monitoring rounds. Indicators covered beneficiary reach, chicken survival, egg production, hatching, vegetable utilization, and implementation barriers. The programme distributed 205 chickens; 204 survived to 30 January 2026, 25 households reported egg production, and three reported successful hatching. Vegetables were harvested for household use and sharing. These findings indicate activation of household food-production assets, not proven improvements in food security or nutritional status. Longer follow-up should measure dietary diversity, egg consumption, food expenditure, income, and asset sustainability.
Co-Authors Dyah Susanti Elly Tugiyanti Elly Tugiyanti Fanni Kusuma Djati Maulina Triani Meylida Ichsyani Normalita Destyarini Satya Maharani br. Simatupang Sri Wahyu Handayani