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THE ANALYSIS OF PHARMACEUTICAL ASPECT OF PRESCRIPTIONS FOR PEDIATRIC PATIENTS IN SUNGAI TUTUNG HEALTH CARE: PRESCRIPTIONS Iisma Rizki Fadhila; Rahmadevi Rahmadevi
INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT (IJHSRD) Vol. 8 No. 1 (2026): INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT
Publisher : STIKes Mandala Waluya Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36566/ijhsrd/Vol8.Iss1/383

Abstract

Background: Pharmaceutical care for pediatric patients requires high accuracy because drug dosage must be adjusted according to age, body weight, and physiological conditions. This study aimed to evaluate the validity of compounded prescriptions for pediatric patients at Sungai Tutung Public Health Center in 2024 based on pharmaceutical aspects, particularly dosage appropriateness. Methods: This study used a descriptive observational design with a retrospective approach. The sample consisted of 60 pediatric compounded prescriptions with 162 drug items. Data were analyzed using descriptive quantitative analysis. Results: The results showed that 42 prescriptions, or 70.0%, were categorized as valid, while 18 prescriptions, or 30.0%, were invalid. Children aged 2–5 years were the most frequent group receiving compounded prescriptions, accounting for 56.7%. Of 162 drug items, 140 items, or 86.4%, had appropriate dosages, while 22 items, or 13.6%, were overdosed. Dosage discrepancies were found in ranitidine, chlorpheniramine maleate, and guaifenesin. Conclusion: This study concludes that the sensuality of pediatric compounded prescriptions was generally adequate; however, improved prescription accuracy and strengthened screening by pharmaceutical personnel are still needed.
Teh Herbal Daun Kelakai (Stenochlaena palustris) sebagai Potensi Fitoestrogen Untuk Produksi ASI : Terinspirasi dari Kearifan Lokal Suku Anak Dalam Jambi Eprina Intami; Ardi Mustakim; Rahmadevi Rahmadevi; Sri Mulyati
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1177

Abstract

This study was conducted in response to the problem of low breast milk production among some breastfeeding mothers, which may adversely affect infant growth and development. One approach to enhancing breast milk production is the utilization of natural substances containing phytoestrogens. Kelakai leaves (Stenochlaena palustris) are a plant traditionally used by the Suku Anak Dalam community as part of local wisdom to support maternal health during the postpartum period. This study aimed to develop kelakai leaf herbal tea as a natural source of phytoestrogens with potential to support increased breast milk production. The research employed a quasi-experimental design using a one-group pre-test and post-test with control group approach, complemented by laboratory analyses including identification of active compounds, simplicia processing, herbal tea formulation, phytochemical screening, and phytoestrogen content analysis. The results demonstrated that kelakai leaves contain flavonoids, saponins, and phytoestrogenic compounds that may contribute to the stimulation of prolactin and oxytocin secretion. Statistical analysis revealed a p-value of 0.000 (p < 0.05), indicating a significant effect of kelakai herbal tea administration on breast milk production among breastfeeding mothers. Based on these findings, it can be concluded that kelakai herbal tea has potential as an alternative herbal beverage derived from local wisdom that may support the success of exclusive breastfeeding programs.
Formulasi Tablet Effervescent Ekstrak Daun Kelor (Moringa oleifera L.) sebagai Pemenuhan Nutrisi untuk Pencegahan Stunting Elpa Giovana Zola; Eka Syafitri; Rahmadevi Rahmadevi; Dea Ayu Agustina
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1239

Abstract

Stunting remains a significant nutritional problem in Indonesia, requiring practical and acceptable nutritional interventions. Moringa oleifera L. leaves are known to contain essential minerals such as zinc, iron, and iodine, which play an important role in supporting optimal growth. This study aimed to formulate effervescent tablets of Moringa leaf extract and evaluate their physical quality as an alternative nutritional supplement for stunting prevention. Moringa leaf extract was obtained through maceration and formulated into four effervescent tablet formulas with varying extract concentrations. The evaluations included granule flow properties, angle of repose, pH, size uniformity, weight uniformity, dispersion time, FTIR analysis, and hedonic testing. The results showed that all formulas met the physical quality requirements of effervescent tablets. The granules exhibited good flow characteristics with an angle of repose below 40°, while the tablet pH values ranged from 4,4 -5,8, indicating suitability for oral administration. All formulas complied with the standards for size and weight uniformity, and the dispersion time ranged from 1 to 2 minutes. FTIR analysis confirmed the presence of hydroxyl, carbonyl, nitroso, and benzene functional groups associated with flavonoids, saponins, and tannins, which contribute beneficial mineral content. Based on physical and organoleptic evaluations, Formula 2 showed the best combination of extract content and granule flow properties, while Formula 1 was the most preferred in terms of taste.