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The antioxidant activity and stability of yogurt fortified with rosella (Hibiscus sabdariffa Linn) calyx extract Nurkhasanah Mahfudh; Amraini Amelia
Pharmaciana Vol 10, No 3 (2020): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Roselle calyx Â (Hibiscus sabdariffa Linn) contains many anthocyanins. The purpose of this study was to determine the anthocyanin stability and antioxidant activity of rosella calyx extract and rosella calyx fortified in yogurt. Roselle calyx extract (Hibiscus sabdariffa Linn) was obtained by the infundation method using water at 90 Â° C for 15 minutes. Rosella calyx extract was made into yogurt with a concentration of 0%, 2%, 4% and 8%, full cream liquid milk 13% (100 ml), and a 5% bacterial starter combination concentration (1: 1 b/v). The yogurt evaluation included a stability test with storage at 4Â°C and antioxidant activity using the DPPH method on 0, 7, 14, 21, and 28 days. The data was statistically analyzed using Multivariate Analysis of Variance (MANOVA). The anthocyanin stability of the three samples, namely roselle extracts of 2%, 4%, and 8%, significantly different (p <0.05) for each concentration of roselle calyx extract and the antioxidant activity of roselle calyx yogurt in the three samples 2% 4% and 8% were significantly different for each concentration of rosella calyx extract added to yogurt. During storage, anthocyanin stability and antioxidant activity of rosella calyx yogurt extract on day 0 to 7 did not differ significantly, while 14 to 28 were significantly different. The 4% and 8% concentrations of rosella calyx yogurt produce optimal yogurt formula

REVIEW : KARAKTERISTIK FISIK DAN DAYA IRITASI MINYAK ATSIRI BUNGA CENGKEH (Syzygium aromaticum) DALAM BEBERAPA TIPE BASIS SEBAGAI ANTI-INFLAMASI Amraini Amelia; Nining Sugihartini; Hari Susanti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

ABSTRACT This review aims to determine the types of bases that can be used every day, which are effective and efficient as anti-inflammatory drugs. The research method used was to review the development of clove essential oil formulations that have been carried out using various concentrations of various types of bases including M / A type cream, A / M type cream, water soluble base, lotion, emulgel, hydrocarbons, hydrogels and absorbents. The recommended formulation is type M / A cream with a concentration of 5% clove flower essential oil. The types of bases studied were M / A cream, type A / M cream, water soluble base, lotion, emulgel, hydrocarbons, hydrogels and absorption properties which had good physical properties and did not irritate the skin of the test animals. This review refers to several national and international journals released in the last ten years, from 2010 to 2020.

EVALUASI PENYIMPANAN OBAT DI APOTEK MAYANG Amraini Amelia
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 1 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

Background: The storage of the drug must be such that it does not pose a hazard. The existence of a drug arrangement that is not appropriate and regular as well as a narrow spatial arrangement makes the drug located inappropriately based on its place and distribution. The negative impact caused by damaged drugs is not only on the patient, but also on the pharmacy itself. Objective: This study aims to evaluate the drug storage system at Apotek Mayang based on the technical guidelines for pharmaceutical standards at the Pharmacy in 2019. Method: This research is a descriptive observational study, which aims to look at the drug storage system at Apotek Mayang. Results: Based on the results of the research conducted, it can be concluded that drug storage at Apotek Mayang is fully in accordance with the Technical Guidelines for Pharmaceutical Service Standards at Pharmacies in 2019, it can be seen from the percentage results of 86.95% which are appropriate. Conclusion: Drug storage at Apotek Mayang is almost completely in accordance with the technical guidelines for pharmaceutical standards in pharmacies in 2019. Conclusion: Drug storage at Apotek Mayang is almost completely in accordance with the technical guidelines for pharmaceutical standards in pharmacies in 2019.

REVIEW: ANTIBACTERIAL, ANTIFUNGAL AND WOUND HEALING ACTIVITY OF NANOEMULGEL FORMULATIONS AND PHYSICAL CHARACTERISTICS Rodhia Ulfa; Wildan Khairi Muhtadi; Urva Fresiva; Amraini Amelia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1193

Nanoemulgel is an emulsion preparation with a droplet size of 1–100 nm suspended in a hydrogel. This review delves into the research on the impact of incorporating excipient components in nanoemulgel formulations to create products with specific physical attributes for different active ingredients with antifungal, antibacterial, and wound-healing properties. The research approach involves comparing articles on nanoemulgel preparation formulations with different combinations of active ingredients and excipients, as well as their pharmacological effects. Enhancing the level of active ingredients and altering the excipients can boost the effectiveness of nanoemulgel formulations in combating fungi, bacteria, and promoting wound healing. The review includes articles published within the past decade. Keywords: Nanoemulgel, Pharmacological activity, Physical characteristics, Review

Phytochemical Analysis and Determination of MIC and MFC of Cacao Leaves Extract (Theobroma cacao L.) against Malassezia furfur Lestari, Siti Marwah; Camelia, Leonyta; Rizki, Widya Twini; Pratama, Septa; Khutami, Chindiana; Amelia, Amraini; Rahmadevi, Rahmadevi; Andriani, Yuni
Jurnal Jamu Indonesia Vol. 9 No. 2 (2024): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v9i2.316

Pityriasis versicolor is a disease caused by Malassezia furfur. One of the plants that can potentially act as antifungal is cacao leaves (Theobroma cacao L.), which contain several secondary metabolite compounds, including alkaloids, flavonoids, tannins, quinones, terpenoids, and saponins. This study aims to determine the phytochemical analysis and the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of cacao leaves ethanolic extract against M. furfur. Extracts were obtained by maceration using 70% ethanol and phytochemicals analysis using Herborne’s method. Furthermore, the extracts were made into concentrations’ variations of 3.125%; 6.25%; 12.5%; 25%; 50%; and 100% for testing antifungal activity, with 10% DMSO as negative control and 2% Ketoconazole and Itraconazole as positive controls. MIC was performed with liquid macrodilution method, and MFC was performed with spread method. The results of phytochemical analysis showed that the extract contained alkaloids, flavonoids, phenols, tannins, quinones, terpenoids and saponins. MIC value was obtained at concentration of 50% and MFC value was obtained at 100%. Cacao leaves ethanolic extract with concentration of 50% can inhibit M. furfur’s growth and with 100% can eliminate M. furfur.

Program Pendampingan Berbasis Herbal untuk Pencegahan Anemia pada Remaja Putri di SMAN 4 Muaro Jambi Amraini Amelia; Chindiana Khutami; Yesi Mustika Sari
PaKMas: Jurnal Pengabdian Kepada Masyarakat Vol 5 No 1 (2025): Mei 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/pakmas.v5i1.3319

Anemia is a health problem that requires special attention, especially among adolescents, due to its high prevalence and harmful impact on future generations. Data from Riskesdas 2018 shows that the prevalence of anemia in Indonesia is 26.8% in children aged 5-14 years and 32% in those aged 15-24 years. This community service program aims to prevent anemia and improve food security among adolescents at SMAN 4 Muaro Jambi through preparation, socialization, training, technology implementation, mentoring, and evaluation phases. The methods used include counseling, cadre training, and herbal product creation. Mandatory outputs include activity videos, media publications, and increased partner knowledge, along with additional outputs such as a guidebook and scientific articles. Significant results from this program include increased adolescent knowledge about anemia prevention and food security, cadre training for simple Hb level checks, and training on making simple herbal products for anemia prevention, such as lemongrass butterfly pea flower tea, roselle tea, and turmeric tamarind herbal drink. This program is expected to serve as a model for other schools and help reduce the prevalence of anemia in Jambi Province.

Formulasi dan Evaluasi Lipstik Berbasis Parafin Solid serta Lanolin sebagai Emolien dan Penstabil Citra Bunga Lestari; Amraini Amelia
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 5 (2025): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i5.1631

This study aims to design and evaluate lipstick preparations by utilizing solid paraffin as the base ingredient and lanolin as an emollient and stabilizer. Solid paraffin was chosen because of its dense properties at room temperature and having the ability to form a stable lipstick structure. In addition, paraffin can provide a smooth, durable surface, and provide good smearing power. On the other hand, lanolin is known as a natural emollient ingredient that functions to moisturize and protect the lips from dryness. Lanolin also has water-retaining properties (occlusive) so that lip moisture is maintained even if the lipstick is used for a long time. The process of making lipstick is carried out by the melting method using indirect heating to maintain the stability of the material and prevent color and aroma degradation. All materials are accurately weighed, then put into beaker glass and heated over three legs using a Bunsen lamp. During heating, the ingredients are gently stirred so that all the components, including solid paraffin and lanolin, melt and mix homogeneously. Once the mixture reaches the desired consistency, the formula is poured into the lipstick mold and allowed to set at room temperature until ready for use. The results of the evaluation test showed that the combination of solid paraffin and lanolin was able to create lipstick with an optimal solid texture, even color, not easy to crack, and had a smooth application power on the surface of the lips. Lanolin plays a big role in providing a soft, moisturizing effect and adding a natural shine to the lips. Meanwhile, solid paraffin helps maintain the shape of the lipstick so that it doesn't break easily when applied. This study also highlights the importance of comparing the composition of ingredients to produce lipsticks that have a stable melting point, good application power, and appropriate adhesion.

Pengaruh SPF terhadap Stabilitas dan Efektivitas Lip Balm Alami dari BEESWAX dan Minyak Kelapa Naifah Nahda; Amraini Amelia
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 5 (2025): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i5.1634

The lips are one of the most sensitive parts of the body and are highly vulnerable to damage from ultraviolet (UV) radiation from sunlight. Unlike other parts of the skin, the lips lack oil glands, making them more prone to dryness, chapping, and inflammation when not properly protected. One common method to maintain lip moisture and health is the use of lip balm. Natural lip balms made from ingredients such as beeswax and coconut oil are widely used due to their excellent emollient properties, which help moisturize and provide a protective layer on the surface of the lips. However, using natural lip balm alone may not be sufficient to offer complete protection, particularly against the harmful effects of UV rays. Therefore, innovation is needed by incorporating Sun Protection Factor (SPF) into natural lip balm formulations to enhance protection from sun exposure. This study aims to evaluate the effect of adding SPF to lip balm formulations based on beeswax and coconut oil, focusing on UV protection effectiveness, product stability, and moisturizing ability. The method involved formulating two types of lip balm—one with SPF and one without. UV protection effectiveness was tested using in vitro spectrophotometry, while moisturizing ability was assessed by measuring skin moisture content on the lips. In addition, physical characteristics such as texture, color, and stability under various storage conditions were analyzed. The results showed that the lip balm with added SPF provided significantly higher UV protection compared to the formulation without SPF. Furthermore, the addition of SPF did not reduce the moisturizing performance of beeswax and coconut oil and did not interfere with the overall product stability. In conclusion, integrating SPF into natural lip balm formulations is an effective innovation to enhance the protective function of lip care products without compromising their moisturizing benefits or user comfort. This combination provides a holistic solution for maintaining lip health while preventing UV-induced damage.

Formulasi Dan Uji Stabilitas Fisik Lip Balm Alami Berbahan Dasar Cera Flava Untuk Perlindungan Bibir Pada Praktikum Farmasetika Dea Lestari; Amraini Amelia
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 5 (2025): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i5.1638

Lip balm is a cosmetic product designed to protect and maintain the moisture of the lips, especially from environmental factors that can cause dry, cracked, or irritated lips, such as low temperatures and wind. Dry lips can interfere with comfort and appearance, making protection with lip balm essential. This study aims to formulate and evaluate a lip balm preparation made from a combination of natural and chemical ingredients, such as cera flava, oleum cacao, nipagin, glycerin, lanolin, and the addition of powder dye. These ingredients were chosen because of their ability to maintain lip moisture, provide protection against external factors, and ensure long-term safety for use. The lip balm manufacturing process begins with heating the primary ingredients, cera flava and oleum cacao, which are melted first. After the primary ingredients have melted, additional ingredients such as nipagin, glycerin, lanolin, and powder dye are added gradually. The mixture is stirred carefully to ensure that all ingredients are evenly blended. Once all the ingredients are well-mixed, the liquid mixture is poured into molds and allowed to cool and harden. This process is crucial for achieving the desired lip balm texture, which should not be too hard or too soft and should facilitate easy application to the lips. Based on the analysis results, the formulated lip balm demonstrates good physical stability, without significant changes in color, odor, or texture during testing. The lip balm also provides ease of use, with a smooth texture that is easy to apply to the lips. The results of this study show that the combination of ingredients used can produce an effective lip balm product that maintains lip moisture and provides optimal protection against harsh environmental conditions, such as low temperatures.

EVALUASI PENYIMPANAN OBAT DI APOTEK MAYANG Amraini Amelia
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 1 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: The storage of the drug must be such that it does not pose a hazard. The existence of a drug arrangement that is not appropriate and regular as well as a narrow spatial arrangement makes the drug located inappropriately based on its place and distribution. The negative impact caused by damaged drugs is not only on the patient, but also on the pharmacy itself. Objective: This study aims to evaluate the drug storage system at Apotek Mayang based on the technical guidelines for pharmaceutical standards at the Pharmacy in 2019. Method: This research is a descriptive observational study, which aims to look at the drug storage system at Apotek Mayang. Results: Based on the results of the research conducted, it can be concluded that drug storage at Apotek Mayang is fully in accordance with the Technical Guidelines for Pharmaceutical Service Standards at Pharmacies in 2019, it can be seen from the percentage results of 86.95% which are appropriate. Conclusion: Drug storage at Apotek Mayang is almost completely in accordance with the technical guidelines for pharmaceutical standards in pharmacies in 2019. Conclusion: Drug storage at Apotek Mayang is almost completely in accordance with the technical guidelines for pharmaceutical standards in pharmacies in 2019.

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