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All Journal Majalah Kedokteran Bandung Folia Medica Indonesiana Jurnal Kedokteran Health Notions Manuju : Malahayati Nursing Journal Jurnal Respirasi (JR) JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Majalah Biomorfologi (Biomorphology Journal) Cardiovascular and Cardiometabolic Journal (CCJ) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Cerdika: Jurnal Ilmiah Indonesia Jurnal Widya Medika

Soebroto, Heroe

Department Of Cardiothoracic And Vascular Surgery, Faculty Of Medicine Universitas Airlangga, Dr Soetomo General Academic Hospital, Surabaya Indonesia

Author-ID : 1104656

Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 18 Documents Claim Missing Document

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Pemberian Asam Hialuronat untuk Menurunkan Adesi Epicardium pada Kelinci (Oryctolagus cuniculus) Pasca Operasi Perikardiotomi Ansyori, Maz Isa; Soebroto, Heroe
Jurnal Kedokteran Vol 7 No 3 (2018)
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Latar belakang: Setiap operasi ulang pada pasien yang telah menjalani prosedur operasi jantung terbuka maka risiko operasi menjadi lebih berat. Hal ini paling disebabkan oleh proses adhesi yang terjadi di rongga mediastinum. Tujuan penelitian ini membuktikan asam hialuronat dapat mengurangi terjadinya adhesi eperikardium paska perikardiotomi. Metode: Penelitian ini merupakan studi eksperimental dengan pendekatan Posttest-Only Control Group Design. Sampel terbagi menjadi dua kelompok. Sebanyak 8 ekor kelinci mendapat perlakuan pemberian asam hialuronat pada jaringan epicardium setelah dilakukan sternotomi, sedangkan delapan ekor tidak mendapat perlakuan. Dilakukan pengamatan selama 8 minggu kemudian jaringan epicardium dari kelinci diperiksa secara makroskopis (skor adhesi) dan secara histopatologi pada setiap masing-masing kelompok. Hasil: Rerata Adhesion Tenacity Score pada kelompok kontrol (2,25Ã‚Â±0,77) lebih besar dibanding dengan kelompok perlakuan (1,25Ã‚Â±0,46) dan perbedaan secara statistik bermakna (p<0,05). Pada uji rerata Adhesion Tissue Thickness pada kelompok perlakuan lebih rendah dibandingkan dengan kelompok kontrol yaitu 88,98 Ã‚Â± 30,64 Ã‚Âµm dibandingkan dengan 40,24 Ã‚Â± 17,5 Ã‚Âµm dan perbedaan secara statistik bermakna (p<0,05). Kesimpulan: Pemberian anti adhesi berupa asam hialuronat dapat dipertimbangkan pada kasus operasi Pericardiotomy sebagai terapi utama akan memberikan efek anti adhesi sehingga dapat menurunkan morbiditas dan mortalitas pada saat dilakukan reoperasi. Katakunci pericardialadhesion,AdhesionTenacityScore,AdhesionTissueThickness,Pericardiotomy,Hyaluronic Acid, anti-adhesion substance

Correlation Between The History of Previous Lower Extremity Amputation as a Risk Factor for the Subsequent Lower Extremity Amputation in Diabetic Patients Among RSUD Dr. Soetomo Patients in 2018 Mochamad Wildan; Sony Wibisono; Heroe Soebroto
Health Notions Vol 4, No 10 (2020): October
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn41008

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia. Complications are common among patients with this condition, such as diabetic foot syndrome, which is the presence of foot ulcer associated with neuropathy, PAD, and infection, and is a major cause of LEA. Aim of this research is to analyze the correlation between previous LEA as a risk factor for the subsequent LEA in patients with Diabetic Foot among patients in RSUD Dr. Soetomo, Surabaya from January-December 2018. This is descriptive cross-sectional study. Data was analyzed using descriptive statistic and correlation test with Microsoft Excel 2007 and SPSS 20. Statistical testing was performed using Spearman’s rank correlation and Cohen J criteria with significance level of P55 years old (62.9%). Mostly have undergone LEA (74.3%) while the remaining have undergone LEA twice (17.1%). There is a significant correlation between initial LEA and the subsequent LEA (p0.01). Keywords: diabetes mellitus; lower extremity amputation; risk factors; RSUD Dr. Soetomo

Mortality Risk Factors in Tetralogy of Fallot Patients Undergoing Total Correction Juliana Juliana; Yan Efrata Sembiring; Mahrus Abdur Rahman; Heroe Soebroto
Folia Medica Indonesiana Vol. 57 No. 2 (2021): June
Publisher : Universitas Airlangga

A total correction is a preferred treatment for Tetralogy of Fallot patients in every part of the world. However, the mortality in developing countries was as high as 6.9% to 15.3%. This was a retrospective analytic study that analyzed pre and post-operative risk factors that affected mortality on TOF patients that were performed total correction in Indonesia. A total of 47 TOF patients that were performed total correction from January 2016 to September 2019 were enrolled in this study based on the inclusion criteria. Preoperative and post-operative data were obtained from medical records. In this research, the majority of mortality was found in male patients (39.3%), while the female’s rate was lower (36.8%). Overall mortality was 38.3% and one operative death was found. The average age of patients was 84.12 months (12-210 months), whereas the average height (85.56 ± 36.17cm vs. 112.93 ± 21.73) and weight (17.22kg vs. 28.21kg) were lower for mortality patients. Some significant preoperative variables were identified as mortality risk factors such as: age below 60 months (p=0.047), smaller weight and height (p=0.008; p=0.002), abnormal hematocrit (p=0.002), and oxygen saturation below 75% (p=0.018). Significant post-operative risk factors included: temperature above 38.5⁰C (p=0.000), and ventilator time of more than 48 hours (p=0.033). In conclusion, the mortality of TOF patients undergoing a total correction in developing countries was quite high. It was associated with some risk factors, such as younger age, lower weight and height, low oxygen saturation, post-operative fever, and prolonged ventilator time.

Characteristics of Heart Failure Patients based on Its Causes in Camelia Hospitalization Room Dr. Soetomo General Hospital Surabaya January - December 2017 Chronica Elsa Retta Lumban Tobing; Budi Baktijasa Dharmadjati; Heroe Soebroto
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 11 No. 1 (2020): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V11I12020.32-35

Introduction: Heart failure is one of cardiovascular diseases which becomes a global health problem, especially in Indonesia. It’s a clinical syndrome caused by variety of underlying diseases. Different causes that cause heart failure in patients will certainly lead to different manifestations and outcomes. Methods: This research was a descriptive study using secondary data taken from the patient's medical records. The number of samples in this study were 197 patients with heart failure in Camelia Hospitalization Room Dr. Soetomo General Hospital Surabaya. Sampling technique was total sampling. The variables were age, sex, stage, symptoms, physical examination, and pharmacological treatment. The data were analyzed descriptively. Results: Most heart failure causes in this hospital was coronary heart disease (40.6%). Patients aged 46-65 years old and male patients were more dominant although the difference was not really significant. Male patients were dominant in heart failure due to coronary heart disease and hypertension, meanwhile female patients were dominant in heart valve disease and other causes. Most patients in all causes of heart failure were diagnosed at advanced stage, such as stage III (35.5%) and stage IV (35.5%). Main symptom that was found more in the patients was dyspnea (70.1%), which could be found in coronary & heart valve disease. Physical examination results were based on the causes. Most pharmacological treatments that the patients had were Furosemide (88.3%) and Spironolactone (73.6%). Conclusion: Coronary heart disease still becomes the main cause of heart failure. Heart failure was more common in early and late elderly (46-65 years old), with male patients were more dominant. More patients were diagnosed at advanced stage. Symptom that was found more was dyspnea. Physical examination results were various based on its causes. Pharmacological treatments that the patients had gotten were Furosemide, kind of diuretics, and Spironolactone, kind of aldosterone antagonist.

TEG's Utility to Detect Hypercoagulability in Adult Patients at Post-Cardiac Surgery Using Cardiopulmonary Bypass in ICU Hildegardis Dyna Dumilah; Hartono Kahar; Arifoel Hajat; Philia Setiawan; Heroe Soebroto
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 27, No 1 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v27i1.1615

The use of Cardiopulmonary Bypass (CPB) in adult patients of cardiac surgery disrupts the coagulation system. The mostcommon complication of the coagulation system is bleeding; however, that does not rule out the possibility of a dangeroushypercoagulation condition. A quick and precise coagulation test can provide clues for clinicians to predict futurehemostatic disorders or determine interventional therapy. aPTT and PT are standard laboratory tests, which are limited todetect a deficiency of coagulation factors. Thromboelastography (TEG) test (R time, K time, α angle, MA, and LY30) providesan overview of the entire coagulation and fibrinolysis process with faster results. A 2.7 mL citrate blood sample was takenand tested in a TEG®5000 device, then centrifuged. The plasma was then tested for aPTT and PT using the Sysmex CS-2100idevice. Bleeding volume was measured from chest drain 1-2 hours in the ICU after chest closure in the operating room.Bleeding criteria were as follows: > 1.5 mL/kg/hour for 6 hours consecutively in 24 hours or > 100 mL/hour. The resultsshowed 30 patients with no clinically significant bleeding. A significant correlation was found between PT and bleedingvolume at IV hour (p=0.008, r= 0.472). There was no correlation between aPTT and TEG (R time, K time, α angle, MA, andLY30) with the bleeding volume at I, II, III, and IV hours. There was a hypercoagulation indication of the TEG test of 56.7%,which showed clinical importance for the patient. PT can be used to analyze changes in bleeding volume at IV hour and TEGis more superior to detect hypercoagulability of adult patients after cardiac surgery with CPB.

Thoracic ectopia cordis: A case report Danang Himawan Limanto; Heroe Soebroto
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 1, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss1.art15

Ectopia Cordis is a congenital anomaly in which the heart is located abnormally outside the thoracic cavity. Aetiology of this defect is still unclear with the incidence rate of 8:1,000,000 live births. Clinical manifestations usually present as severe sepsis respiratory distress due to heart failure as a result of an intrinsic abnormality of the heart which makes the management more challenging. Five days-old female newborn was referred to our hospital by a local doctor with “beating lump” outside her chest. The diagnosis of complete thoracic ectopia cordis was made by clinical examination, chest x-ray, and echocardiography. The Echo showed complete AV canal, ASD, mild pulmonary stenosis, and atrioventricular valve regurgitation. Palliative surgery was then undertaken with the initial goal to limit exposure and prevent further infection. The heart is covered with bovine pericardium sutured along the edge of the chest wall defect. Ectopia cordis is rare and has a poor prognosis especially thoracic and cervical types. Definitive surgery, to replace the heart to the thoracic cavity, is difficult to perform because of the hypoplastic thoracic cavity. Attempt to do palliative surgery, such as covering the heart with either skin flap or other material, becomes the choice of treatment in this case although there is no evidence reported of adulthood survivors.

Primary repair of tetralogy of fallot and major aorto-pulmonary collateral arteries with suspected Noonan syndrome: A rare case Heroe Soebroto; Erdyanto Akbar; Arief Rakhman Hakim
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 3, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss3.art13

Tetralogy of Fallot (TOF) is a congenital heart disease that includes ventricular septal defect (VSD), pulmonary stenosis (PS), right ventricular hypertrophy (RVH), and an overriding aorta. A cyanotic heart defect can develop aorto-pulmonary collateral (APCA) to supply underperfused pulmonary beds. Genetic syndromes can occur in 20% of patients with TOF. In developing countries, diagnosed genetic syndromes associated with heart defects have not been covered by health insurance, even though outcomes of primary repair remain unknown. This study reported a case of an 11-year-old boy with cyanosis since birth, dyspnoea on effort, growth delays, learning problems, scoliosis, micropenis, hypertelorism, exophthalmos, facial dysmorphism, cryptorchidism, and major aorto- pulmonary collaterals. The patient underwent an echocardiographic study. It showed VSD malalignment with overriding aorta of 48%, critical pulmonary stenosis, and size of pulmonary arteries that were favourable for primary repair. Cardiac catheterization showed classic Fallot with normal coronary arteries and major aortopulmonary collateral arteries (MAPCA) arising. The patient underwent percutaneous coil embolization just before surgery. There was a problem during induction, the anaesthetist found that it was hard to place the ETT because there was membrane-like covering the trachea. Next, a median sternotomy was conducted, and aortic cross-clamping was achieved. Right atriotomy was performed, and it provided exposure to the malalignment VSD. A longitudinal pulmonary arteriotomy was made to expose infundibular stenosis. Infundibulectomy was performed, and it reconstructed the MPA with a pericardial patch. The VSD was closed by using a PTFE patch. The patient was transferred to an ICU afterward. Post-operative echocardiography showed a good outcome, and 15 days after surgery the patient was discharged. It could be concluded that primary repair of TOF with MAPCAs and suspected Noonan syndrome was conducted successfully.

Clinical Profile of Post-Operative Treatment Duration in Pediatric Congenital Heart Disease Patients Reido Dafa Annafis; I Ketut Alit Utamayasa; Heroe Soebroto
Malahayati Nursing Journal Vol 4, No 11 (2022): Volume 4 Nomor 11 2022
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v4i11.7394

ABSTRACT CHD (Congenital Heart Disease) is still a dangerous disease that causes a high infant mortality rate in the world. Nowadays, there are two groups of actions to treat congenital heart disease, surgical management and non-surgical management. This study discusses Clinical Profile of Post-Operative Treatment Duration in Pediatric Congenital Heart Disease Patients. Fourty medical records used for this analytical descriptive study were obtained from Department of Pediatrics and Department of Thoracic, Cardiac, and Vascular Surgeons, Dr. Soetomo General Hospital, Surabaya, Indonesia. This study described post operative treatment duration in pediatric congenital heart disease patients. The total patients in the study were 40 pediatric patients with the majority being female, namely 52.50% with higher mortality rate in patients with congenital heart disease with surgical treatment (16.6%). Most patients with CHD in children with surgical and non-surgical treatment were diagnosed in the infant age group (0-5 years), namely 31 patients (77.50%) with 5 surgical treatment patients and 26 non-surgical treatment patients. The majority of patients with congenital heart disease with surgical and non-surgical management in good nutritional status (60.00%). Most cases of cyanotic congenital heart disease are tetralogy of fallot (50%) with all of cases treated with cardiac catheterization for non-surgical treatment, zero case surgical treatment, and 5 cases without surgical or non surgical treatment. Acyanotic cases are ASD (28.56) with 4 cases cardiac catheterization, 2 cases treated with ASO device, and 1 case with ASD closure as surgical treatment. The duration of hospitalization after the procedure was shorter in good nutritional status (3.2 days) in both surgical and non-surgical treatment while shorter duration after procedure also appeared in cases of congenital heart disease with non-surgical treatment (4.25 days). CHD patients with non-surgical treatments have shorter duration compared to patients with surgical treatment. Most CHD cases were TOF for cyanotic and ASD for acyanotic with higher mortality rate in surgical treatment. Good nutritional status were found in both of the CHD treatment. Most CHD patients with surgical and non-surgical treatment were infant, female. Keywords: CHD, Surgical, Non-Surgical, Pediatrics, Treatment Duration

Quality of Life in Children with Acyanotic Congenital Heart Disease in Dr. Soetomo General Hospital, Surabaya, Indonesia Salsabila Fabianca Alsaid; Taufiq Hidayat; Heroe Soebroto
Cardiovascular and Cardiometabolic Journal Vol. 3 No. 1 (2022): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v3i1.2022.1-8

Abstract: Acyanotic congenital heart disease is a disease that affects the patient physically and psychologically result in the patient not being able to carry out his life normally. As a result, patients will feel lonely, rejected, and isolated from society which makes social integration more difficult. The picture of quality of life in acyanotic CHD patients can be used as a therapeutic evaluation material to improve quality of life. Material and Methods: This study used descriptive analytic method with total sampling. The variable studied was quality of life using Pedsql Inventory 3.0 Cardiac Module questionnaire to the patients aged 2-18 years who were treated at Dr. Soetomo General Hospital Surabaya in 2019—2020. Results: 74 Acyanotic CHD patients (left to right shunt) obtained an average quality of life of 73.89 ± 9.79 with low-value aspects, namely Heart Problems and Therapy I (72.92 ± 18.20), Cognitive (59.53 ± 18.40), and Communication (71.40 ± 24.21). There was a significant difference in the type of combination diagnosis compared with other types with a significance of 0.014 (p <0.05). Conclusion: Aspects that have a negative impact on the patient's quality of life are Heart Problems and Therapy I, Cognitive, and Communication. The Combination type is a diagnosis with the lowest quality of life compared to other types. Keywords: Acyanotic CHD, PedsQL, Quality of life

Faktor Risiko Pasien Acute Limb Ischemia Fhahira Rizkhika Admadiani; J Nugroho Ekoputranto; Heroe Soebroto; Agus Subagjo
Cerdika: Jurnal Ilmiah Indonesia Vol. 2 No. 4 (2022): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Acute Limb Ischemia (ALI) is a classification of peripheral arterial disease that causes decreased blood flow to the extremities, with onset within 2 weeks and characterized by 6 'P's, namely pallor, pain, perishing cold, pulseless, paralysis, and paresthesia. This can be identified through several risk factors, including: diabetes, smoking, gender, high blood pressure, age,hyperlipidemia, atrial fibrillation (AF) and diabetes. This study aims to identify risk factors in ALI patients. Hospital identification. Soetomo Surabaya Period January 2016 – March 2019. This study uses a total sampling technique. This study uses a descriptive cross sectional method with medical record instruments and direct interviews with patients. Twenty-five (25) patients were known to have ALI (14 males and 11 females), and the age of the patients ranged from 65 to 69 years (20%). The causes of risk included a history of smoking obtained from 10 subjects (40%), a history of hypertension in 7 subjects (28%), a history of stage 1 hypertension, a history of diabetes mellitus with the highest blood glucose test value > 126 mg/dl up to 10 people. . (62.5%), with a history of hyperlipidemia, with total cholesterol within normal limits of up to 4 (66.7%), LDL in the normal range of not more than 3 (60%), and HDL with 2 with low HDL values (40%). ), and the highest triglyceride levels were within the normal range. Electrocardiographic examination revealed 7 patients (28%) with atrial fibrillation. Most of the ALI patients in this study were aged between 65 and 69 years and were male. Most ALI patients in this study were 65-69 years old and males. The most common risk factors for ALI patients were hypertension, diabetes mellitus, and hypercholesterolemia.

Co-Authors Abed Nego Okthara Sebayang Agus Subagjo Ahmed Eliaan Shaker Abuajwa Ansyori, Maz Isa Arief Rakhman Hakim Arifoel Hajat Chronica Elsa Retta Lumban Tobing Danang Himawan Limanto Dharmadjati, Budi Baktijasa Dhihintia Jiwangga Suta Winarno Dhihintia Jiwangga Suta Winarno Erdyanto Akbar Fhahira Rizkhika Admadiani Gerardo AK Laksono Hartono Kahar, Hartono Heri Suroto Hermina Novida, Hermina Hildegardis Dyna Dumilah I Gusti Agung Made Adnyanya Putra I Gusti Agung Made Adnyanya Putra2 Ito Puruhito Jeffrey Jeswant Dillon Jeffrey Jeswant Dillon Juliana Juliana Ketut Putu Yasa Kusworo, Afila Reza Mahrus A Rahman, Mahrus A Marsa Hendra Utomo Mochamad Wildan Paul L Tahalele Puruhito Puruhito Putranto, J.Nugroho Eko Reido Dafa Annafis Reviano, Moses Orvin Salsabila Fabianca Alsaid Sembiring, Yan Efrata Setiawan, Philia Sony Wibisono Sri Pramesthi Wisnu Bowo Negoro Sri Pramesthi Wisnu Bowo Negoro Taufiq Hidayat Taufiq Hidayat Widodo Widodo Wiwin Is Effendi

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