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All Journal Folia Medica Indonesiana Jurnal NERS Jurnal Kedokteran HIGEIA (Journal of Public Health Research and Development) Health Notions JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Ners SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Indonesian Archives of Biomedical Research (InABR) Indonesia Journal of Physical Medicine and Rehabilitation Indonesia Journal Physical Medicine and Rehabilitation Sense : Journal of Film and Television Studies Jurnal Penyakit Dalam Indonesia Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD)
Sony Wibisono
Department Of Internal Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Decision Sciences, Operations Research & Management Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Hubungan Kepribadian dengan Kontrol Glikemik Pasien Diabetes Mellitus Tipe 2 di RSUD Dr. Soetomo Surabaya Emmy Amalia; Suksmi Yitnamurti; Sony Wibisono
Jurnal Kedokteran Vol 8 No 1 (2019)
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v8i1.326

Abstract

Latar Belakang: Diabetes Mellitus (DM) adalah penyakit kronis yang paling umum diderita orang dewasa dengan angka kematian yang besar akibat komplikasi, sehingga penting untuk mengidentifikasi faktor-faktor yang berhubungan dengan kontrol glikemik pada pasien DM, salah satunya faktor kepribadian. Selama ini, peran kepribadian relatif diabaikan. Penelitian ini bertujuan untuk menganalisis hubungan antara unsur kepribadian dengan kontrol glikemik pasien DM tipe 2 di Unit Rawat Jalan Poli Diabetes RSUD dr. Soetomo. Metode: Penelitian analitik observasional cross sectional dengan metode consecutive sampling terhadap pasien DM tipe 2 yang berkunjung ke Unit Rawat Jalan Poli Diabetes RSUD Dr Soetomo Surabaya. Instrumen yang digunakan meliputi skala Personality Psychopathology Five (PSY-5) Tes Kesehatan Mental Indonesia (TKMI), Perceived Stress Scale (PSS), dan kadar HbA1c darah. Data disajikan dalam tabel dan grafik dengan uji regresi logistik ganda dan analisis statistik menggunakan SPSS 19.0. Hasil: Skor unsur psychoticism pasien DM tipe 2 di Poli Diabetes RSUD Dr. Soetomo Surabaya lebih tinggi dari unsur kepribadian lain (mean 57,54; median 56; skor terendah 38; skor tertinggi 93); 59,8% pasien mempunyai tingkat perceived stress sedang; 77% pasien mempunyai kadar HbA1c yang tidak terkontrol; unsur kepribadian psychoticism secara bermakna berhubungan dengan perceived stress (p 0,031; β 0,064) dan unsur kepribadian discontraint secara bermakna berhubungan negatif dengan perceived stress (p 0,018; β -0,108); didapatkan hubungan negatif antara perceived stress dengan kontrol glikemik (p 0.001; β -3,571). Kesimpulan: Kepribadian berhubungan dengan kontrol glikemik pada pasien DM tipe 2 di unit rawat jalan Poli Diabetes RSUD Dr. Soetomo Surabaya melalui perceived stress.
TINGKAT PENDIDIKAN BUKAN MERUPAKAN PREDIKTOR RISIKO DIABETES BERDASARKAN SKORING AMERICAN DIABETES ASSOCIATION Agustianto, Rafiv Fasya; Mudjanarko, Sony Wibisono; Prabowo, Gwenny Ichsan
HIGEIA (Journal of Public Health Research and Development) Vol 4 No 1 (2020): HIGEIA: January 2020
Publisher : Jurusan Ilmu Kesehatan Masyarakat, Fakultas Ilmu Keolahragaan, Universitas Negeri Semarang, Indonesia

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Abstract

ABSTRAK Jawa Timur termasuk 10 besar provinsi dengan prevalensi diabetes melitus (DM) tertinggi di Indonesia. Penelitian ini bertujuan untuk menganalisis hubungan antara tingkat pendidikan dan risiko diabetes di Surabaya. Penelitian ini merupakan suatu studi korelasi analitik dengan metode cross sectional, dilaksanakan pada tanggal 9 Desember 2018 dengan metode skoring berdasarkan kuesioner American Diabetes Association (ADA). Skor < 5 diklasifikasikan sebagai risiko rendah, sedangkan skor ? 5 dikategorikan sebagai risiko tinggi menderita diabetes melitus (DM). Data diproses dengan uji analisis chi-square menggunakan perangkat lunak IBM SPSS Statistic 23. Sebanyak 113 subjek terlibat dalam penelitian ini, dengan 92 orang di antaranya memenuhi kriteria inklusi. Secara keseluruhan, 54 dari 92 subjek termasuk kelompok berisiko tinggi (58,70%), dengan 34 orang di antaranya berpendidikan rendah (62,96%). Mayoritas subjek adalah wanita (76,09%) dan lansia berusia lebih dari 60 tahun (34,78%). Secara statistik, hasil penelitian ini menunjukkan bahwa tingkat pendidikan bukan merupakan prediktor risiko diabetes berdasarkan skoring American Diabetes Association (p> 0,05), namun distribusi data menunjukkan prevalensi diabetes lebih banyak terdapat pada subjek berpendidikan rendah, wanita, dan lansia. ABSTRACT East Java is among the top 10 provinces with the highest prevalence of diabetes mellitus (DM) in Indonesia. This study aims to analyze the relationship between education level and diabetes risk in Surabaya. This cross-sectional study was conducted on December 9, 2018, with scoring method based on American Diabetes Association (ADA) questionnaire. Score < 5 is classified as low risk, while score ? 5 is categorized as high risk of suffering from diabetes mellitus (DM). Data were processed by chi-square analysis using IBM SPSS Statistics 23 software. A total of 113 subjects were involved in this study, with 92 of them fulfilling the inclusion criteria. Overall, 54 of 92 subjects were having high-risk (58.70%), 34 of them were low-educated (62.96%). Most of subjects were women (76.09%) and elderly aged over 60 years (34.78%). Statistically, this study indicates that education level is not a predictor of diabetes risk based on American Diabetes Association score (p> 0.05), however data distribution indicates diabetes prevalence was higher in low-educated, women and elderly subjects.  
Tingkat Pendidikan Bukan Merupakan Prediktor Risiko Diabetes Berdasarkan Skoring American Diabetes Association Agustianto, Rafiv Fasya; Mudjanarko, Sony Wibisono; Prabowo, Gwenny Ichsan
HIGEIA (Journal of Public Health Research and Development) Vol 4 No 1 (2020): HIGEIA: January 2020
Publisher : Jurusan Ilmu Kesehatan Masyarakat, Fakultas Ilmu Keolahragaan, Universitas Negeri Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRAK Jawa Timur termasuk 10 besar provinsi dengan prevalensi diabetes melitus (DM) tertinggi di Indonesia. Penelitian ini bertujuan untuk menganalisis hubungan antara tingkat pendidikan dan risiko diabetes di Surabaya. Penelitian ini merupakan suatu studi korelasi analitik dengan metode cross sectional, dilaksanakan pada tanggal 9 Desember 2018 dengan metode skoring berdasarkan kuesioner American Diabetes Association (ADA). Skor < 5 diklasifikasikan sebagai risiko rendah, sedangkan skor ≥ 5 dikategorikan sebagai risiko tinggi menderita diabetes melitus (DM). Data diproses dengan uji analisis chi-square menggunakan perangkat lunak IBM SPSS Statistic 23. Sebanyak 113 subjek terlibat dalam penelitian ini, dengan 92 orang di antaranya memenuhi kriteria inklusi. Secara keseluruhan, 54 dari 92 subjek termasuk kelompok berisiko tinggi (58,70%), dengan 34 orang di antaranya berpendidikan rendah (62,96%). Mayoritas subjek adalah wanita (76,09%) dan lansia berusia lebih dari 60 tahun (34,78%). Secara statistik, hasil penelitian ini menunjukkan bahwa tingkat pendidikan bukan merupakan prediktor risiko diabetes berdasarkan skoring American Diabetes Association (p> 0,05), namun distribusi data menunjukkan prevalensi diabetes lebih banyak terdapat pada subjek berpendidikan rendah, wanita, dan lansia. ABSTRACT East Java is among the top 10 provinces with the highest prevalence of diabetes mellitus (DM) in Indonesia. This study aims to analyze the relationship between education level and diabetes risk in Surabaya. This cross-sectional study was conducted on December 9, 2018, with scoring method based on American Diabetes Association (ADA) questionnaire. Score < 5 is classified as low risk, while score ≥ 5 is categorized as high risk of suffering from diabetes mellitus (DM). Data were processed by chi-square analysis using IBM SPSS Statistics 23 software. A total of 113 subjects were involved in this study, with 92 of them fulfilling the inclusion criteria. Overall, 54 of 92 subjects were having high-risk (58.70%), 34 of them were low-educated (62.96%). Most of subjects were women (76.09%) and elderly aged over 60 years (34.78%). Statistically, this study indicates that education level is not a predictor of diabetes risk based on American Diabetes Association score (p> 0.05), however data distribution indicates diabetes prevalence was higher in low-educated, women and elderly subjects.
Cardiac Tamponade in a Patient With Hypothyroidism: A Case Report Hermifa Dwi Aninnaimah; Sony Wibisono
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17560

Abstract

Cardiac tamponade as a manifestation in newly diagnosed hypothyroidism is a rare condition becausefluid accumulate slowly. We present a 38-year-old woman with massive pericardial effusion withcardiac tamponade findings in echocardiography without hemodynamic disturbance. Pericardiocentesiswas done, but pericardial effusion was not improved. Other secondary causes of pericardial effusionincluding inflammation, infection, autoimmune disease, and malignancy were ruled out. The patienthad a history of thyroidectomy 4 years prior and thyroid function test confirm the diagnosis ofhypothyroidism. The patient was given levothyroxine with initial dose of 400 mcg and continued with100 mcg daily. The pericardial effusion significantly improved in a week.
Comparison of the Effect of Glycemic Control on the Incidence of Fetal Macrosomia and Large for Gestational Age in Gestational Diabetes Mellitus Patients; A Systematic Review Natasha Tiara Bernadette; Budi Prasetyo; Sony Wibisono; Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17972

Abstract

Background: Gestational diabetes mellitus (GDM) can be managed with blood glucose control management, which includes a healthy lifestyle, insulin therapy, and oral anti-diabetic drug (OAD) medications when needed. Sub-optimally or poorly managed GD Mmay lead to arisk of complications, one of which is an abnormal growth in the fetus. This study aimed to compare the effect of blood glucose control management on the incidence of fetal macrosomia and large for gestational age (LGA) births in patients with GDM. Methods: This systematic review study obtained data from formerly published studies from the Science Direct database. The article search method used the characteristics of PICO (Population, Intervention, Comparison, Outcome) and compiled using the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method. Conclusion: The use of medical nutrition therapy (MNT) and exercise in the therapeutic regimen, as well as routine monitoring of glycemic levels are very important to control the patient’s glycemic level. The use of metformin can increase the success of therapy due to reduced levels of LGA and macrosomia in GDM patients
In-Vitro Differentiation Adipose-Derived Mesenchymal Stem Cells into Pancreatic Progenitor Cells Hermina Novida; Agung Pranoto; Askandar Tjokroprawiro; Sony Wibisono; Purwati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14752

Abstract

Background: Adult stem cells are currently reliable sources of mesenchymal stem cells for regenerativetherapy, include diabetes mellitus. The aim of this study is to develop endocrine pancreatic progenitor cellscharacterized by Pdx1 and insulin expression from rat adipose-derived mesenchymal stem cells using twosteps in-vitro differentiation.Methods: In this experimental study, ADMSCs were isolated from rat adipose tissue and exposed toinsulinogenic differentiation medium containing nicotinamide, activin A and glucagon-like peptide-1 (GLP1). After induction, the existence of pancreatic progenitor cells (PPCs) was confirmed by immune-stainingassay of Pdx1 and insulin.Results: After three weeks of in-vitro differentiation, expression of Pdx1 and insulin proteins showed upas green in the immunofluorescence assay. Immunofluorescence intensity of Pdx1 was higher in PPCs thanin ADMSCs control (p<0.05). Immunofluorescence intensity of insulin was also higher in PPCs than inADMSCs control (p<0.05). Therefore, in-vitro differentiation was successful to develop PPCs from ratADMSCsConclusion: This study has demonstrated the in-vitro differentiation of ADMSCs into PPCs that expressedPdx1 and insulin
Correlation Between The History of Previous Lower Extremity Amputation as a Risk Factor for the Subsequent Lower Extremity Amputation in Diabetic Patients Among RSUD Dr. Soetomo Patients in 2018 Mochamad Wildan; Sony Wibisono; Heroe Soebroto
Health Notions Vol 4, No 10 (2020): October
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn41008

Abstract

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia. Complications are common among patients with this condition, such as diabetic foot syndrome, which is the presence of foot ulcer associated with neuropathy, PAD, and infection, and is a major cause of LEA. Aim of this research is to analyze the correlation between previous LEA as a risk factor for the subsequent LEA in patients with Diabetic Foot among patients in RSUD Dr. Soetomo, Surabaya from January-December 2018. This is descriptive cross-sectional study. Data was analyzed using descriptive statistic and correlation test with Microsoft Excel 2007 and SPSS 20. Statistical testing was performed using Spearman’s rank correlation and Cohen J criteria with significance level of P55 years old (62.9%). Mostly have undergone LEA (74.3%) while the remaining have undergone LEA twice (17.1%). There is a significant correlation between initial LEA and the subsequent LEA (p0.01). Keywords: diabetes mellitus; lower extremity amputation; risk factors; RSUD Dr. Soetomo
Effect of High Fat Diet on Body Weight, Visceral Fat Weight, and PPARG Expressions on Visceral Fat in Mice Cantika Putri Melyana; Purwo Sri Rejeki; Sony Wibisono Mudjanarko; Lilik Herawati; Mohammad Anam Al-Arif
Folia Medica Indonesiana Vol. 57 No. 3 (2021): September
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (355.87 KB) | DOI: 10.20473/fmi.v57i3.16213

Abstract

Obesity becomes a global epidemic nowadays. The high-fat diet is used as an alternative therapy for obesity. The optimal composition of a high-fat diet to reduce body weight is still unknown. This study aimed to determine which components of a high-fat diet can decrease body weight, visceral fat, and PPARG expression of visceral fat. This study was conducted at the Faculty of Veterinary Medicine, Universitas Airlangga, for three months by using a randomized post-test only control group design. Fifty male mice, 2-3 months old, 18-30 grams were adapted for one week given standard diet AIN93-M, then mice were divided into five groups, namely K1 (control group, 12% fat, 20% protein, 62% carbs); K2 (30% fat, 60% proteins, 0% carbs); K3 (45% fat, 45% protein, 0% carbs);  K4 (60% fat, 30% protein, 0% carbs); and K5 (75% fat, 15% protein, 0% carbs). Bodyweight was measured before and after treatment, then the visceral fat and PPARG expressions were evaluated. Statistical comparisons were performed using Statistical Package for the Social Sciences (SPSS) software. After treatment, there were forty-three mice. The body weight and visceral fat weight of the mice with a high-fat diet were decreased. The most significant changes in body weight were in K4 with -9,60 ± 3,806 grams reduction. The bodyweight of mice in K5, slightly increased than K2-K4. This could be caused by the hormesis phenomenon. PPARG expressions decreased in groups with a high-fat diet but increased in K5. The composition of a high-fat diet in group K4 was the most optimal to decrease the body weight, visceral fat, and PPARG expressions in mice
Family Experience of Caring for a Diabetes Mellitus Patient: A Qualitative Study Indah Wulandari; Kusnanto Kusnanto; Sony Wibisono; Titin Puspitasari
Jurnal Ners Vol. 15 No. 1Sp (2020): Special Issue
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jn.v15i1Sp.19010

Abstract

Introduction: Diabetes mellitus is a chronic disease that requires lifelong care. The treatment of diabetes mellitus patients at home requires a family role so then the patients can optimize their care. The diabetes complications can be reduced as a result. The aim of this study was to explore the family experience of treating diabetes mellitus patients at home.Methods: A semi-structured phenomenological approach including inductive thematic analysis was used in this research.  Thirteen family members of diabetes patients participated in the discussion. Participant recruitment was focused on families that have treated diabetes patients for more than 1 year with no complications. Data saturation occurred after 2-3 meetings per participant.Results: The experiences of the family members while caring for diabetes mellitus patient can be used to determine the presence of 5 themes: family feelings that appear when caring for diabetes mellitus patients, patient adherence to taking medication, patient’s disobedience of their diet, patient’s disobedience of activity and  the family expectations of the futureConclusion: In every theme, family experience obstacles arise between the families’ wants and the patients’ needs.  Diet and activity became a major obstacle to diabetic care at home. Some topics needed more attention, such as the information and support provided for the family.
The Influence of Elastic Taping on Dynamic Muscular Control (Dynamic Control Ratio) Evertor-Invertor Ankle in Type 2 Diabetes Mellitus Male with Complications of Peripheral Neuropathy Yuli Indah Kurnia; Imam Subadi; I Putu Alit Pawana; Sony Wibisono
Surabaya Physical Medicine and Rehabilitation Journal Vol. 2 No. 2 (2020): SPMRJ, AGUSTUS 2020
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v2i2.17673

Abstract

Background: Type 2 Diabetes Mellitus (DM) with Peripheral Neuropathy often have impared control of muscle strength that increases the risk of fall. Elastic taping (ET) is a special elastic band that can stretch up to 140% and could facilitate muscle contraction.Aim: To prove the influence of ET on the dynamic muscular control balance between evertor and invertor muscles of the ankle in type 2 DM male with peripheral neuropathy.Material and methods: This study used a pre-post one grup study, with10 type 2 DM male with peripheral neuropathy. All subjects were examined for ankle evertor-invertor dynamic control ratio (DCR) with isokinetic dynamometer at 600/sec and 1200/sec before elastic taping (ET), 30 minutes after ET, at the third day of ET aplication and 3 days after ET was released. Elastic taping was applied with functional tehniques on the both ankles.Result: There were no significant differences between with and without the application of KT in the ankle evertor-invertor DCR in both side. The p value were same in both sides, at 600/sec after 30 minute ET (p=0.72), at the third day of ET aplication (p=0,24), 3 days after released ET (p= 0,88) and at 1200/sec after 30 minute ET (p=0,17).Conclusion: Elastic taping did not improve the ankle evertor-invertor DCR in type 2 DM male patients with peripheral neuropathy.
Co-Authors AGUNG PRANOTO Agung Pranoto Agustianto, Rafiv Fasya Akbar, Royhan Al arif, Mohammad Anam Andrianto Andrianto Andrianto Ardiany, Deasy Ariana, Audy Meutia Arifoel Hajat Askandar Tjokroprawiro Audy Meutia Ariana Bambang Hermanto Bambang Purwanto Budi Prasetyo Cantika Putri Melyana Chandra Adi Irawan Primasatya Damayanti Tinduh Desi Rianti Rahmadhani Dian W Astuti Emmy Amalia Farahiyah, Jihaan Fauqa Arinil Aulia Febri Kurniawati Ferdy Royland Marpaung Gusti Agung Ayu Ira Kencana Dewi Hanestya Oky Hermawan Hendra Gunawan HERAWATI, LILIK Hermifa Dwi Aninnaimah Hermina Novida, Hermina Imam Subadi Indah Wulandari Jayawarsa, A.A. Ketut Komaratih, Evelyn Kurnia Alisaputri Kusnanto Kusnanto Laylatul Fitriah Mukarromah Lefi, Achmad Leonita Anniwati Maftuchah Maftuchah Martha Kurnia Kusumawardani Mas'adah Mas'adah Meity Ardiana Mochamad Wildan Natasha Tiara Bernadette Nur Sulastri Nuvus, Alviyatul Ainin Pawana, I Putu Alit Permana, Putu Bagus Dharma Prabowo, Gwenny Ichsan Primasatya, Chandra Adi Irawan Purwati Rejeki, Purwo Sri Rifki Esa Syahnarki Safira Raissa Dwi Putri SATRIYAS ILYAS Sidarti Soehita Soebroto, Heroe Soelistijo, Soebagijo Adi Sri Lestari Utami Suksmi Yitnamurti Surdiana Thomas Jatiman Titin Puspitasari Ula Nur Pramesti Karman Widati Fatmaningrum Widyanrika, Farahdiva Audrey Wigati, Kristanti Wanito Winna Adelia Amru Yuli Indah Kurnia