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All Journal AL KAUNIYAH Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JSFK (Jurnal Sains Farmasi & Klinis) JFL : Jurnal Farmasi Lampung Jurnal Farmasi Indonesia Jurnal Insan Farmasi Indonesia Pharmaceutical And Biomedical Sciences Journal (PBSJ) Eduvest - Journal of Universal Studies
Nelly Suryani
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences

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UJI AKTIVITAS ANTIBAKTERI GEL EKSTRAK ETANOL DAUN ANGSANA (Pterocarpus indicus Willd.) TERHADAP BAKTERI Staphylococcus aureus Nelly Suryani Djamain; Vivi Anggia; Nia Fachrunisa
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.488

Abstract

Angsana leaves (Pterocarpus indicus Willd.) contain flavonoids, saponins, tannins, alkaloids, glycosides, triterpenoids, and steroids can be used as an active substances that formulated into antibacterial formulation gel. In this study, ethanolic extracts of Angsana leaves are formulated into gel form to optimize the antibacterial activity from the extracts. The purpose of this study belongs to determine the differences antibacterial activity of ethanolic extracts of Angsana leaves before and after being formulated into gel form. Antibacterial activity test was determined by using disc diffusion method due to Kirby-Bauer method. Based on the results, it showed that formulation contains 0.09 mg extract formed 8 mm inhibition zone and 9 mg extract without formulation formed 16 mm inhibition zone. By comparing the amount of extracts to the inhibitory zone, it is known that extract which formulated into a gel form has greater activity than extract without formulated.
Uji Stabilitas Spironolakton Terhadap Perubahan pH dengan Menggunakan Kromatografi Cair Kinerja Tinggi (KCKT) Nelly Suryani; Yardi Supandi; Ririn Astri Sabdowati
Jurnal Farmasi Indonesia Vol 16 No 1 (2019): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (780.444 KB) | DOI: 10.31001/jfi.v16i1.450

Abstract

Spironolactone is an aldosterone diuretic antagonist for hypertension. In practice spironolactone is sometimes combined with other drugs, and in unconscious patients the drug must use a feeding tube and be susceptible to instability. The object of this study was to see the effect of pH changes on spironolactone tablets which were crushed and suspended in water. The method of measuring spironolactone levels using High Performance Liquid Chromatography based on methods in the United State Pharmacopeia. Spironolactone suspension was made at pH 3, 5, 7, and 9 with sampling time in minutes 0, 15, 30, 45, and 60. The results showed that the level of spironolactone at pH 3 was ≤ 0%, pH 5 was 74% - 100%, at pH 7 it was in the range of 27% - 61%, and at pH 9 was 38% - 54%. This explains that percent of spironolactone at pH 3.7, and 9 at all sampling times did not match the minimum therapeutic level in the monograph. Only at pH 5 does the level of spironolactone still match the levels specified in the monograph. In this study it can be concluded that changes in pH can significantly reduce spironolactone levels in suspension.
UJI VIABILITAS MIKROENKAPSULASI Lactobacillus casei MENGGUNAKAN MATRIK NATRIUM ALGINAT Nelly Suryani; Ofa Suzanti Betha; Qurry Mawaddana
JFL : Jurnal Farmasi Lampung Vol. 8 No. 1 (2019): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.425 KB) | DOI: 10.37090/jfl.v8i1.80

Abstract

Lactobacillus casei is a species that is often used as a probiotic but is not resistant to very acidic environments. Microencapsulation in this study was carried out using the extrusion method with a matrix of sodium alginate concentrations of 2%, 3%, and 4%. The three concentrations of sodium alginate were tested for their ability to protect Lactobacillus casei ATCC 393 from the effects of gastric acid simulation fluid. From the viability test, the results of enumeration of cells in the concentration of sodium alginate 2%, 3% and 4% were 3.08 x 106 colonies / gram; 7.41 x 104 colonies / gram; and 1.01 x 107 colonies / gram. The three MLNs with the three concentrations were incubated in gastric acid simulation fluid (0.08 M HCl; 0.2% NaCl; pH 1.5) for 120 minutes. The enumeration results of MLN viability after testing the gastric acid liquid at a concentration of 4% were 4.5 x 103 colonies / gram, whereas at a concentration of 2% and 3% the viability value was
Pengkajian Administrasi Resep Anak Di Salah Satu Puskesmas Kabupaten Tangerang Yardi Saibi; nelly suryani; Shella Desilia Pratiwi
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 8 No. 2 (2021)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v8i2.4909

Abstract

Pengkajian resep anak penting untuk dilakukan untuk mencegah terjadinya medication error. Penelitian ini bertujuan untuk melakukan pengkajian resep pasien anak-anak di salah satu puskesmas yang ada di wilayah kabupaten Tangerang. Penelitian ini merupakan penelitian cross sectional deskriptif. Populasi adalah seluruh resep pasien pediatri pada rawat jalan. Sampel yang diambil sebanyak 100 resep secara acak sederhana . Kriteria inklusi yaitu seluruh resep pasien pediatri rawat jalan pada bulan Desember tahun 2018 di unit ruang pelayanan kefarmasian. Kriteria eksklusi yaitu resep pasien pediatri yang tidak dapat terbaca oleh peneliti. Klirens etik penelitian didapatkan dari Komite Etik Penelitian Kesehatan Fakultas Kedokteran Universitas Indonesia. Data diolah dengan menggunakan analisa statistik univariat. Hasil penelitian menunjukkan bahwa aspek kelengkapan administrasi yang sudah lengkap yakni nama pasien, umur dan tanggal penulisan resep (100%). Tiga aspek lainnya yang sama sekali tidak memenuhi kelengkapan yakni jenis kelamin pasien, berat badan pasien serta ruangan/unit asal resep (0%). Dari persyaratan farmasetik, aspek bentuk sediaan dan kekuatan sediaan sama sekali tidak ditemukan pada resep (0%). Sedangkan dosis, jumlah dan aturan pemakaian obat memenuhi syarat kelengkapan. Dapat disimpulkan bahwa pengkajian resep secara administrasi dan farmasetik di puskesmas ini perlu dilakukan sebagai upaya untuk mengevaluasi kelengkapan resep yang sesuai dengan standar pelayanan yang berlaku.
Profil Pemberian Informasi ObatTerhadap Pasien dengan Resep Antidiabetes di Apotek Tangerang Selatan Nelly Suryani; Yardi Saibi; Vidia Arlaini Anwar
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 2, No 1 (2020)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (198.016 KB) | DOI: 10.15408/pbsj.v2i1.15280

Abstract

Providing drug information is very important to be conducted by pharmacists for patients who redeem drugs at their pharmacy, especially patients who fall into the priority category for counseling such as patients undergoing diabetes mellitus treatment. This study aimed to create a profile of drug / counseling information given by pharmacies in the South Tangerang area to patients with prescription of antidiabetic drugs. This was a descriptive cross sectional study. Data were collected by the simulation patient method played by 6 seniorundergraduate pharmacy students. Simple random sampling was used in taking 100 pharmacies from the population of pharmacies registered at the city health office. The scenario was in the form of a new prescription contained of 5 mg of glibenclamide without repetition which was intended for family member of the simulated patient. To identify officers who provided drug information, simulation patients asked confirmation questions to ascertain whether they were pharmacists or not. The results showed that as many as 88.65% of officers who provided drug information to simulated patients were non-pharmacists. The most commonly given information by the pharmacist was the frequency of drug use followed by the time of use and the purpose of use (indications) which were 100%, 90.91% and 54.55%, respectively. While the information items provided by non-pharmacists were the frequency of drug use followed by the intended use and time of use associated with meal times which were 83.72%, 61.63% and 40.70% respectively. It can be concluded that more the drug information provided to patients is carried out by unappropriate professionals namely pharmacists. Drug information delivered to patients both by pharmacists and by non-pharmacists is not maximally done. The role of pharmacists in providing drug information to DM patients needs to be increased
Soil Transmitted Helmint on Lettuce (Lactuca sativa L.) From Plantation and Post-Irradiation Narti Fitriana; Nelly Suryani; Yani Indriyani; Priyanti Priyanti
Al-Kauniyah: Jurnal Biologi Vol 15, No 2 (2022): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v15i2.24513

Abstract

AbstractSoil-Transmitted Helminth (STH) is a group of intestinal parasitic nematode worms that can infect humans. One of the transmissions to humans is consuming lettuce grown on soil media. This study aims to identify the types of intestinal parasitic nematodes found in lettuce and soil from plantations based in the Regency of Bogor, Cianjur, and Bandung and analyze the prevalence, intensity, and dominance categories before and after irradiation. The irradiation dose used was 5 kGy with a gamma irradiation source [60Co]. The descriptive method used in this study where the samples were collected from 9 sampling points at each study site. Identification showed that there were 3 types of intestinal parasitic nematodes found in lettuce, namely Ascaris lumbricoides (1,833 eggs), Strongyloides stercoralis (2 larvae), and Trichuris trichiura (91 eggs). The highest prevalence was found in A. lumbricoides (100%) which is classified %) classified as very severe contamination, very severe, and superinfection intensity of contamination criteria. The highest dominance of intestinal parasitic nematodes was found in A. lumbricoides. In the post-irradiated lettuce and soil samples was found eggs of A. lumbricoides and T. trichiura. The eggs of A. lumbricoides were the most common, 321 eggs were found in the post-irradiated lettuce, while 11 eggs of T. trichiura were found therein. Irradiation techniques can be used for the application of free-STH lettuce in the future, however, maintaining fresh food sanitation shall always be a priority preventive effort.AbstrakSoil Transmitted Helminth (STH) merupakan kelompok cacing nematoda parasit intestinalis yang dapat menginfeksi manusia. Salah satu transmisi kepada manusia adalah mengonsumsi selada yang ditanam pada media tanah. Penelitian ini bertujuan untuk mengidentifikasi jenis cacing nematoda parasit intestinalis yang ditemukan pada selada dan tanah asal perkebunan di Kabupaten Bogor, Kabupaten Cianjur, dan Kabupaten Bandung serta menganalisis kategori prevalensi, intensitas, dan dominansinya sebelum dan pascairadiasi. Dosis iradiasi yang digunakan adalah 5 kGy dengan sumber iradiasi gamma [60Co].  Metode deskriptif digunakan pada penelitian ini, sampel dikoleksi dari 9 titik sampling pada setiap lokasi. Identifikasi menunjukkan terdapat 3 jenis cacing nematoda parasit intestinalis yang ditemukan pada selada yaitu Ascaris lumbricoides (1.833 telur), Strongyloides stercoralis (2 larva), dan Trichuris trichiura (91 telur). Prevalensi tertinggi ditemukan pada A. lumbricoides (100%) tergolong tingkat kontaminasi kategori selalu dengan kriteria kontaminasi sangat parah, intensitas kontaminasi kategori super infeksi. Dominansi cacing nematoda parasit intestinalis tertinggi ditemukan pada A. lumbricoides. Pada selada dan sampel tanah pasca iradiasi ditemukan telur A. lumbricoides dan T. trichiura. Telur A. lumbricoides merupakan yang terbanyak, pada selada pasca iradiasi ditemukan 321 sedangkan T. trichiura ditemukan 11. Teknik iradiasi dapat digunakan untuk aplikasi selada bersih dari STH di masa datang namun menjaga sanitasi pangan segar merupakan usaha preventif prioritas. 
Kosmetik Rambut menurut Ibn Sina dalam Al-Qanun fi'l-Tibb II; Komponen Kimia dan aktivitasnya - Review Sabrina Dahlizar; Suci Ahda Novitri; Ofa Suzanthi Betha; Putri Kurniasih; Nelly Suryani
Jurnal Sains Farmasi & Klinis Vol 10, No 1 (2023): J Sains Farm Klin 10(1), April 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.1.1-9.2023

Abstract

Buku Al-Qanun Fi’l Tibb merupakan karya Ibnu Sina mengenai prinsip – prinsip pengobatan yang disusun dalam 5 jilid dan telah digunakan sebagai dasar –dasar pengobatan dan menjadi kurikulum dalam pendidikan kedokteran dan farmasi sampai abad ke 18.  Salah satu dari rangkaian buku tersebut yaitu jilid ke_2 disusun oleh Ibn Sina berupa materia medika yang menguraikan aktivitas dan khasiat, cara penggunaan, dan karakteristik serta deskripsi sebanyak 790 bahan obat tunggal berasal dari tanaman, hewan dan bahan alam lainnya. Penelitian ini bertujuan untuk mengeksplorasi komponen metabolit sekunder utama yang terkandung di dalam tanaman yang berdasarkan hasil pengujian Ibnu Sina memiliki aktivitas sebagai kosmetik rambut. Dari hasil penelitian didapatkan bahwa tanaman - tanaman tersebut mengandung komponen metabolit sekunder utama diantaranya terpen, asam fenolat, flavonoid, asam lemak, tanin, alkaloid, saponin, kuinon, dan feniletanoid glikosida. Tanaman dengan komponen utama berupa terpenoid berjumlah 9 tanaman, asam fenolat sebanyak 5 tanaman, flavonoid, asam lemak, alkaloid, dan tannin masing – masing 4 tanaman, senyawa kuinon saponin dan feniletanoid glikosida masing -masing sebanyak 1 tanaman.
Quantitative Study of Antibiotic Usage in Pneumonia Patients: Systematic Literature Review Delina Hasan; Yardi Saibi; Nelly Suryani; Muhammad Yanis Musdja; Vidia Arlaini; Dzdzikra D.A Dzdzikra D.A
Eduvest - Journal of Universal Studies Vol. 4 No. 1 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i1.996

Abstract

Pneumonia caused more than 2,56 million deaths in 2017 worldwide. With the high number of pneumonia sufferers, the use of antibiotics will also increase. This study aims to describe the quantity of antibiotic use in pneumonia patients using the Systematic Literature Review method. The literature search was conducted through the PubMed, Sciencedirect, Mendeley, BMC, and Google Scholar databases. The literature used is a journal of the last 10 years that discusses the use of antibiotics in pneumonia patients calculated by the ATC/DDD system. Of the total 19 journals included in the study, 8 journals were from Indonesia. A total of 5 journals discussed antibiotics used in CAP (Community-Acquired Pneumonia), 2 journals in HAP (Hospital-Acquired Pneumonia), 2 journals in VAP (Ventilator-Associated Pneumonia), 2 journals were non-specific, and the remainder covered several types of pneumonia. The class of antibiotics with the highest DDD value is fluoroquinolones, with an average use of 41,81 DDD/100 patient-days; 17,29 DDD/100 bed days; and 0,0696 DDD/1000 inhabitants per day, and third-generation cephalosporins, with an average use of 15,86 DDD/100 patient-days and 28,31 DDD/100 bed days. The antibiotic with the highest DDD value was levofloxacin, with an average use of 31,29 DDD/100 patient-days; 12,22 DDD/100 bed days; and 0,0612 DDD/1000 inhabitants per day, and ceftriaxone, with an average use of 12,51 DDD/100 patient-days and 26,33 DDD/100 bed days. The most widely used antibiotics in the treatment of CAP and HAP are third-generation cephalosporins, while penicillin is the most commonly used in VAP.
Co-Authors Astri Fajriani Delina Hasan Dzdzikra D.A Dzdzikra D.A Farida Sulistiawati Muhammad Yanis Musdja Narti Fitriana, Narti Nia Fachrunisa Ofa Suzanthi Betha Ofa Suzanti Betha Priyanti Priyanti Putri Kurniasih Qurry Mawaddana Ririn Astri Sabdowati Sabrina Dahlizar Shella Desilia Pratiwi Suci Ahda Novitri Vidia Arlaini Vidia Arlaini Anwar Vivi Anggia, Vivi Yani Indriyani Yardi Saibi Yardi Saibi Yardi Supandi Yardi Yardi