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<![CDATA[PELAYANAN KONSELING PASIEN OLEH APOTEKER DI KOTA MEDAN PATIENT COUNCELING SERVICE BY PHARMACIST IN MEDAN CITY ]]>
<![CDATA[Astuti, Sri Puji]]>;
<![CDATA[saibi, yardi]]>;
<![CDATA[Dasuki, Asep]]>
<![CDATA[ Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol 5 No 1 (2018) ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Prof. DR. HAMKA ]]>
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DOI: 10.22236/farmasains.v5i1.3630
<![CDATA[Latar belakang: Konseling apoteker merupakan suatu proses komunikasi dua arah yang sistematik antara apoteker dan pasien untuk mengidentifikasi dan memecahkan masalah yang berkaitan dengan obat dan pengobatan. Layanan konseling oleh apoteker ini merupakan salah satu standar layanan klinik yang harus dilakukan oleh seorang apoteker. Tujuan: Penelitian ini bertujuan untuk mendeskripsikan layanan konseling apoteker di kota Medan Sumatra Utara. Metode penelitian: Desain penelitian adalah deskriptif-eksploratif menggunakan teknik survei terhadap apoteker yang menjadi sampel di kota Medan pada bulan Juli ? Agustus 2015. Data dikumpulkan dengan metode pasien simulasi dan menggunakan alat ukur check list, resep dokter. Data dianalisis dengan statistik deskriptif. Hasil dan Kesimpulan: Apoteker yang bersedia memberikan layanan konseling atas permintaan pasien simulasi sebesar 66,67% dari 60 orang sampel. Informasi yang banyak disampaikan oleh apoteker adalah nama obat, waktu penggunaan obat, frekuensi, jumlah obat yang diberikan, dan efek samping. Poin informasi yang disampaikan oleh kurang dari 50% apoteker adalah kontraindikasi, onset obat, rute obat, bentuk sediaan obat, interaksi obat, penyimpanan obat dan pembuangan obat. Secara umum kualitas poin informasi obat yang disampaikan oleh apoteker sudah baik dan sesuai dengan informasi yang ada dalam literatur. Konseling belum menjadi aktifitas yang dilakukan oleh apoteker secara rutin atas inisiatif sendiri.]]>
<![CDATA[Kualitas Pelayanan Informasin Obat (Konseling) di Apotek Kabupaten Garut ]]>
<![CDATA[Riza Permana Suci]]>;
<![CDATA[Yardi Saibi]]>;
<![CDATA[Asep Dasuki]]>
<![CDATA[ Jurnal Pharmascience Vol 5, No 1 (2018): Jurnal Pharmascience ]]>
Publisher : <![CDATA[Program Studi Farmasi FMIPA Universitas Lambung Mangkurat ]]>
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DOI: 10.20527/jps.v5i1.5779
<![CDATA[ABSTRAK Peran apoteker telah mengalami pergeseran dalam beberapa dekade terakhir. Peran yang sebelumnya lebih berorientasi kepada produk (product oriented) telah beralih kepada peran yang lebih berfokus kepada pasien (patient oriented). Salah satu peran yang berfokus kepada pasien adalah pelaksanaan pemberian informasi obat ataupun konseling di apotek. Penelitian ini bertujuan untuk melihat kualitas pelayanan pemberian informasi obat dan atau konseling oleh tenaga kefarmasian di apotek di wilayah Kabupaten Garut, Jawa barat. Rancangan penelitian berupa potong lintang dengan pendekatan deskriptif. Untuk mengamati pelaksanaan pemberian informasi obat/konseling, dilakukan dengan pendekatan simulasi pasien penggunakan resep yang mengandung obat antidiabetes dan obat lain yang saling berinteraksi menurut literatur. Penelitian ini mendapat izin dari dinas kesehatan kabupaten Garut. Hasil penelitian menunjukkan bahwa pemberian informasi obat oleh tenaga kefarmasian kepada pasien di apotek wilayah garut dilakukan oleh asisten apoteker dan apoteker. Kualitas layanan pemberian informasi obat yang dilakukan oleh apoteker sedikit lebih baik jika dibandingkan pelayanan yang dilakukan oleh asisten apoteker. Kualiltas layanan informasi obat yang dilakukan oleh apoteker masuk kategori kurang baik sedangakan yang diberikan oleh asisten apoteker dalam kategori buruk. Informasi obat pada pasien dengan penyakit kronis hendaknya dilakukan secara langsung oleh apoteker. Apoteker perlu meningkatkan kemampuannya dalam memberikan informasi obat kepada pasien. Kata Kunci : apoteker komunitas, apotek, peran apoteker, Garut, Indonesia ABSTRACT The pharmacist role in Indonesia as well as in the global world has shifted in the last few decades. The previous role that more focus on product has changed to the role that orient to patient care. One of this new pharmacist role form is giving apropriate information about the drug to patien either in the form of simple information or in the form of more complete i.e counceling in community pharmacy or apothec. This research aimed to evaluate the quality of drug information service and or counselling conducted by pharmacy staff in pharmacy in Garut regency, West Java province. This was a cross- sectional study with descriptive approach. Patient simulation method was used to evalulate the practice of drug information delivery and or counselling by pharmacy staff eithe by pharmacy technician or pharmacist to patient come with antidiabetic prescription. This research was conducted by the permission from publich health office of Garut regency. The result showed that the quality of drug information delivery conducted by pharmacist was slightly better than pharmacy technician did. Pharmacist should served patient with chronic desease such as diabetict directly. Both pharmacy technician and pharmacist need to improve their knowledge and skill in handling patient. Key word : community pharmacist, pharmacy , Pharmacist role, Garut, Indonesia]]>
<![CDATA[Microwave-Assisted Claisen-Schmidt Condensation Reaction of Ethyl p-methoxycinnamate to Synthesize p-Methoxystyryl Ketone Derivatives and Evaluate Anti-inflammatory Activity of Synthetic Products ]]>
<![CDATA[Ismiarni Komala]]>;
<![CDATA[Supandi Supandi]]>;
<![CDATA[Nurmeilis Nurmeilis]]>;
<![CDATA[Yardi Yardi]]>;
<![CDATA[Ofa Suzanti Betha]]>;
<![CDATA[Nurkhyati Putri Indriyani]]>;
<![CDATA[Moethia Moethia]]>;
<![CDATA[Muhamad Beny Setiawan]]>;
<![CDATA[Ghilman Dharmawan]]>;
<![CDATA[Putri Hayati Nufus]]>;
<![CDATA[Noni Tri Utami]]>
<![CDATA[ Journal of Mathematical and Fundamental Sciences Vol. 53 No. 1 (2021) ]]>
Publisher : <![CDATA[Institute for Research and Community Services (LPPM) ITB ]]>
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DOI: 10.5614/j.math.fund.sci.2021.53.1.6
<![CDATA[The rhizome of Kaempferia galanga has been known to contain ethyl p-methoxycinnamate (EPMC) (1) as a main component, which has anti-inflammatory properties. Previously we have reported the structural modification of EPMC (1) to form another ester, nitrostyrene, and cinnammamide derivatives and then studied their structure-activity relationships as anti-inflammatory agent. In continuing our research, in this paper, we report the microwave-assisted Claisen-Schmidt condensation of EPMC (1) to synthesize a series of p-methoxystyryl ketones followed by a study of their anti-inflammatory activity. The reaction begins with microwave-assisted cleavage oxidation of hydrolyzed product of EPMC, p-methoxycinnamic acid (2) with Ca(NO3)2 for the synthesis of p-methoxybenzaldehyde (3). Furthermore, 3 was reacted with acetophenone, ethyl methyl ketone and acetone via microwave-assisted Claisen-Schmidt condensation for the synthesis of (E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one (5a) (E)-1-(4-methoxyphenyl)pent-1-en-3-one (5b) and (E)-4-(4-methoxyphenyl)but-3-en-2-one (5c), respectively. The reaction products were characterized using spectroscopic techniques and were then tested for anti-inflammatory activity using in vitro anti-denaturation of protein assay. It was found that converting EPMC (1) to 5a and 5b reduced anti-inflammatory activity, while 5c retained anti-denaturation activity with an IC50 of 72.8 µg/ml.]]>
<![CDATA[POTENSI HIPOGLIKEMIA DAN HIPERGLIKEMIA PADA PASIEN DIABETES MELITUS TIPE 2 AKIBAT INTERAKSI OBAT ]]>
<![CDATA[Yardi Saibi]]>;
<![CDATA[Delina Hasan]]>;
<![CDATA[Bukhoriah Safitri]]>;
<![CDATA[Vidia Arlaini Anwar]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v5i2.468
<![CDATA[The potency of drug interaction is higher because of the presence of comorbidities and polypharmacy in type 2 diabetes mellitus patient. This study aimed to know the potency of drug interaction event in type 2 diabetes mellitus patient in one of hospital in Jakarta in 2016 which have potency to cause hypoglycemia and hyperglicemia. Data was collected from medical record of type 2 diabetes mellitus patient . The design of this research was cross- sectional. Data retrieval was conducted retrospectively. The sample size in this study was 151 Diabetes mellitus type 2 patients medical record who received antidiabetes and met the inclusion and exclusion criteria. Data analysis was done statistically using univariate analysis . Results showed that female dominated the patient as much as 74,83% with hypertension as the most common comorbidities as much as 28,48%. There were 186 drug interaction event potency with 83,8% of them could cause hypoglicemia while the rest could cause hyperglicemia. Drug interaction with the potency that can cause either hypoglycemia and hyperglycemia that can effect the failure to get the therapeutic goal still be frequent found in patient prescription. Drug interaction event should get appropriate attention from clinical pharmacist in hospital]]>
<![CDATA[Drug Interaction Potency on Type 2 Diabetes Mellitus Patient in Hospital X in South Tangerang ]]>
<![CDATA[Yardi Saibi]]>;
<![CDATA[Delina Hasan]]>;
<![CDATA[Verona Shaqila]]>
<![CDATA[ JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 8, No 3 ]]>
Publisher : <![CDATA[Faculty of Pharmacy, Universitas Gadjah Mada ]]>
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DOI: 10.22146/jmpf.34027
<![CDATA[Drug interaction is an interaction among a drug with other ingredients that prevents the drug from giving certain or expected effect. Such interaction might happen between a drug and other drugs, drugs with food, as well as drugs and disease. Potential drug interaction in patients with type 2 diabetes mellitus in some hospitals had been reported by several previous publications. This study aimed to identify the potential of drug interactions in patients with type 2 diabetes mellitus at Hospital X, South Tangerang. This paper is a descriptive research with retrospective retrieval data. Data were obtained in the form of patient medical records from July 2014 to June 2015. Data analysis was done by descriptive statistic analysis using SPSS version 16. The results showed that there were 90 medical records that fulfilled the inclusion criteria. Of these, 57.7% was found to be potential drug interaction. There are 55 drug interactions that potentially cause hypoglycemia, and there are 21 times that potentially cause hyperglycemia. The severity of interaction in moderate category was 89.39% (total of 66), and the rest was in minor category. Major categories were not found. The potential for drug interactions in type 2 diabetes mellitus patients is quite common and these findings complement the findings of previous published studies. Physicians and pharmacists as health workers who are directly related to the treatment of patients need to increase awareness of the potency of interactions of these drugs.]]>
<![CDATA[AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL 70% DAUN ASHITABA (Angelica keiskei) SECARA IN VIVO DENGAN PENGINDUKSI KARAGENAN ]]>
<![CDATA[Haka As'ada]]>;
<![CDATA[Yardi Saibi]]>;
<![CDATA[Hendri Aldrat]]>
<![CDATA[ JFL : Jurnal Farmasi Lampung Vol. 7 No. 2 (2018): JFL: Jurnal Farmasi Lampung ]]>
Publisher : <![CDATA[Fakultas MIPA Universitas Tulang Bawang Lampung ]]>
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DOI: 10.37090/jfl.v7i2.56
<![CDATA[Ashitaba leaves (Angelica keiskei) or also known as tommorow's leaf is plant that known to have various health benefit, one of them is as an anti-inflammatory activity. The anti-inflammatory activity of ashitaba leaves has been known through in vitro assays. This study aims to determine the anti-inflammatory activity of 70% ethanol extract of ashitaba leaves through in vivo assay. Anti-inflammatory activity was performed on white male rat of Sprague dawley strain with induction method of edema on rat's foot using 1% carrageenan 0.2 ml. Rats were divided into 5 groups. The negative control group was given a 0.5% Na-CMC suspension, a positive control group was given sodium diclofenac suspension of 5.14 mg / kgBW, and the test group was given 70% ethanol extract of ashitaba leaves at a dose of 1000; 2000; and 4000 mg / kgBW suspended in 0.5% Na-CMC. The results showed that in that dose range the 70% ethanol extract of ashitaba leaves had anti-inflammatory activity that did not depend on the dose. Percentage of edema of 70% ethanol extract of ashitaba leaves dose 1000; 2000; 4000 mg / kgBB was significantly different with negative control (p ≤ 0,05) and had percentage of edema inhibition respectively 83,95%, 79,01%, and 80,25%. The results of this study showed that 70% ethanol extract of ashitaba leaves have anti-inflammatory activity. Keywords: Ashitaba, Angelica keiskei, tommorow's leaf, anti-inflammatory, carrageenan.]]>
<![CDATA[PELAYANAN KONSELING PASIEN OLEH APOTEKER DI KOTA MEDAN PATIENT COUNCELING SERVICE BY PHARMACIST IN MEDAN CITY ]]>
<![CDATA[Sri Puji Astuti]]>;
<![CDATA[yardi saibi]]>;
<![CDATA[Asep Dasuki]]>
<![CDATA[ Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 5 No. 1 (2018) ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Prof. DR. HAMKA ]]>
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DOI: 10.22236/farmasains.v5i1.3630
<![CDATA[Latar belakang: Konseling apoteker merupakan suatu proses komunikasi dua arah yang sistematik antara apoteker dan pasien untuk mengidentifikasi dan memecahkan masalah yang berkaitan dengan obat dan pengobatan. Layanan konseling oleh apoteker ini merupakan salah satu standar layanan klinik yang harus dilakukan oleh seorang apoteker. Tujuan: Penelitian ini bertujuan untuk mendeskripsikan layanan konseling apoteker di kota Medan Sumatra Utara. Metode penelitian: Desain penelitian adalah deskriptif-eksploratif menggunakan teknik survei terhadap apoteker yang menjadi sampel di kota Medan pada bulan Juli – Agustus 2015. Data dikumpulkan dengan metode pasien simulasi dan menggunakan alat ukur check list, resep dokter. Data dianalisis dengan statistik deskriptif. Hasil dan Kesimpulan: Apoteker yang bersedia memberikan layanan konseling atas permintaan pasien simulasi sebesar 66,67% dari 60 orang sampel. Informasi yang banyak disampaikan oleh apoteker adalah nama obat, waktu penggunaan obat, frekuensi, jumlah obat yang diberikan, dan efek samping. Poin informasi yang disampaikan oleh kurang dari 50% apoteker adalah kontraindikasi, onset obat, rute obat, bentuk sediaan obat, interaksi obat, penyimpanan obat dan pembuangan obat. Secara umum kualitas poin informasi obat yang disampaikan oleh apoteker sudah baik dan sesuai dengan informasi yang ada dalam literatur. Konseling belum menjadi aktifitas yang dilakukan oleh apoteker secara rutin atas inisiatif sendiri.]]>
<![CDATA[Pengkajian Administrasi Resep Anak Di Salah Satu Puskesmas Kabupaten Tangerang ]]>
<![CDATA[Yardi Saibi]]>;
<![CDATA[nelly suryani]]>;
<![CDATA[Shella Desilia Pratiwi]]>
<![CDATA[ Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 8 No. 2 (2021) ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Prof. DR. HAMKA ]]>
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DOI: 10.22236/farmasains.v8i2.4909
<![CDATA[Pengkajian resep anak penting untuk dilakukan untuk mencegah terjadinya medication error. Penelitian ini bertujuan untuk melakukan pengkajian resep pasien anak-anak di salah satu puskesmas yang ada di wilayah kabupaten Tangerang. Penelitian ini merupakan penelitian cross sectional deskriptif. Populasi adalah seluruh resep pasien pediatri pada rawat jalan. Sampel yang diambil sebanyak 100 resep secara acak sederhana . Kriteria inklusi yaitu seluruh resep pasien pediatri rawat jalan pada bulan Desember tahun 2018 di unit ruang pelayanan kefarmasian. Kriteria eksklusi yaitu resep pasien pediatri yang tidak dapat terbaca oleh peneliti. Klirens etik penelitian didapatkan dari Komite Etik Penelitian Kesehatan Fakultas Kedokteran Universitas Indonesia. Data diolah dengan menggunakan analisa statistik univariat. Hasil penelitian menunjukkan bahwa aspek kelengkapan administrasi yang sudah lengkap yakni nama pasien, umur dan tanggal penulisan resep (100%). Tiga aspek lainnya yang sama sekali tidak memenuhi kelengkapan yakni jenis kelamin pasien, berat badan pasien serta ruangan/unit asal resep (0%). Dari persyaratan farmasetik, aspek bentuk sediaan dan kekuatan sediaan sama sekali tidak ditemukan pada resep (0%). Sedangkan dosis, jumlah dan aturan pemakaian obat memenuhi syarat kelengkapan. Dapat disimpulkan bahwa pengkajian resep secara administrasi dan farmasetik di puskesmas ini perlu dilakukan sebagai upaya untuk mengevaluasi kelengkapan resep yang sesuai dengan standar pelayanan yang berlaku.]]>
<![CDATA[Kajian Metode Peningkat Kepatuhan Pada Pasien Hipertensi: Telaah Literatur Sistematis ]]>
<![CDATA[Suci Ahda Novitri]]>;
<![CDATA[Yardi Saibi]]>;
<![CDATA[Maulia Muhtaromah]]>
<![CDATA[ Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 3, No 1 (2021) ]]>
Publisher : <![CDATA[UIN Syarif Hidayatullah Jakarta ]]>
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DOI: 10.15408/pbsj.v3i1.20357
<![CDATA[: Prevalensi penderita hipertensi terus meningkat secara tajam. WHO memprediksi bahwa pada tahun 2025 orang dewasa di dunia akan menderita hipertensi sekitar 29% dari total penduduk dunia. Salah satu penyebabnya adalah karena ketidakpatuhan pasien hipertensi dalam menjalankan terapinya. Penelitian ini bertujuan untuk mengkaji artikel terkait metode yang dapat digunakan untuk meningkatkan kepatuhan pasien hipertensi serta pengaruhnya terhadap kepatuhan. Penelitian ini menggunakan metode yang terstruktur dan sistematis (Systematic Literature Review). Pencarian artikel dilakukan melalui basis data Pubmed, Science Direct, Google Scholar dan diperoleh sebanyak 22 artikel. Berdasarkan hasil kajian artikel menunjukkan bahwa metode yang dapat digunakan untuk meningkatkan kepatuhan pasien hipertensi yaitu konseling, home care, fokus group diskusi (FGD), video, pemberian leaflet atau brosur edukasi, pemberian pesan singkat (SMS), kotak obat digital, kartu pil (pill box), mobile health dan gabungan beberapa metode. Metode-metode tersebut memiliki pengaruh dalam meningkatkan kepatuhan pasien hipertensi.]]>
<![CDATA[A retrospective descriptive cross-sectional study of Oral Dosage Form Administered in The Form of Suspension to ICU Patients at Hospital X ]]>
<![CDATA[Suryani, Nelly]]>;
<![CDATA[Anwar, Vidia Arliani]]>;
<![CDATA[Saibi, Yardi]]>;
<![CDATA[Dhilasari, Estu Mahanani]]>;
<![CDATA[Dahlizar, Sabrina]]>;
<![CDATA[Betha, Ofa Suzanti]]>;
<![CDATA[Komala, Ismiarni]]>;
<![CDATA[Azzahra, Afifah Nurnishrina]]>
<![CDATA[ Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 2 (2024) ]]>
Publisher : <![CDATA[UIN Syarif Hidayatullah Jakarta ]]>
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DOI: 10.15408/pbsj.v6i2.41341
<![CDATA[Patients in the intensive care unit were often very sick and had lost consciousness. Because they had trouble swallowing, individuals with reduced awareness frequently depended on enteral tubes (NGT) for their daily medical and nutritional requirements. Since not all medications were accessible in parenteral forms, patients who relied on enteral tubes often had issues, including drug stability. Many problems arose in clinical usage when the medication was crushed or suspended and put into the NGT, including drug obstruction in the enteral tube and a reduction in drug stability as a result of the dose form being altered, making the drug unstable. Thus, this study aimed to ascertain the stability of oral suspension medications given to intensive care unit patients. The medical records of intensive care unit patients who had received oral medication therapy at X Hospital in Jakarta were examined retrospectively using a cross-sectional, descriptive approach. According to the statistics, coated tablets accounted for 68% of the most frequently used oral medication preparations. It was highly likely that crushing the coated tablets and administering them via NGT had resulted in tube obstruction. Additionally, 59.26% of the medications used had exhibited hygroscopic qualities, and several had been readily hydrolyzed. Based on these findings, it was concluded that oral medications, particularly crushed-coated tablets, could negatively affect drug stability. Active substances with hygroscopic properties and those prone to hydrolysis were also identified as potential contributors to instability.]]>
