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CRANIAL CHARACTERISTICS, MAXILLOFACIAL, AND SKULL BASE STRUCTURE OF NON-HUMAN PRIMATE (ADULT MACACA FASCICULARIS): A PRELIMINARY STUDY FOR CRANIAL CRANIOTOMY MODEL Bolly, Hendrikus Masang Ban; Indah, Astrina Rosaria; Faried, Ahmad; Noverina, Rachmawati; Arifin, Muhammad Zafrullah; Wirakusumah, Firman Fuad
Majalah Kedokteran Bandung Vol 51, No 2 (2019)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v51n2.1650

The use of non-human primate (NHP) animal models, which anatomical and physiological similarities to human, is important for the sake of learning the anatomical properties. This study aimed to characterize the cranial, maxillofacial, and skull base structures of non-human primates as a potential model suitable for a cranial craniotomy model. Adult Macaca fascicularis (MF) skulls classified asspecificpathogen-free for TB, SIV, SV40, Polio, Foamy virus and Herpes B virus from PT Bio Farma (Persero) Animal Lab. Library were used to represent the anatomical model.The open access database from Mammalian Crania Photographic Archive 2nd Edition (MCPA2) was used for cranial characterization analysis. This study was performed at the Department of Neurosurgery, Dr. Hasan Sadikin General Hospital and the Animal Laboratory of PT. Biofarma (Persero) from November 2018 to January 2019. The skull base structures were assessed for its analogies with its human counterpart. Comparison by t-student analysis between male and female skulls shows the mean male cranial length (CL) is greater than in female (116.68 vs 102.50 mm), with p=0.000; the mean male bizygomatic width (BZB) is greater than in female (79.30 vs 69.70 mm) with p=0.001; the mean male posterior cranial breadth (CBN) is greater than in female (63.40 vs 58.79 mm) with p=0.019; and the mean male cranial base length (CBL) is greater than in female (63.32 vs 57.55 mm), with p=0.001. The skull of MF is suitable for Neurosurgery and Neuroscience study since the MF cranial characterization and structure are similar to that of human. Its structure is ideal for performing craniotomy since it has several characteristics such as cranial vault, maxillofacial structure with huge temporal muscle, and skull base structure. Karakteristik Kranium, Maksilofasial, dan Struktur Dasar Tengkorak Non-human Primate Macaca fascicularis dewasa: Studi Pendahuluan untuk Model Craiotomi Kranium Penggunaan hewan model berasal dari primata bukan-manusia (NHP), dimana secara anatomis dan fisiologis mirip dengan manusia, sangat penting untuk dapat mempelajari struktur anatominya. Penelitian ini bertujuan untuk karakterisasi struktur kranium, maksilofasial dan dasar tengkorak primata (Non-human Primate) yang berpotensi sebagai model penelitian kraniotomi. Tengkorak dewasa Macaca fascicularis (MF) dari Laboratorium Hewan PT Biofarma (Persero), bebas infeksi TBC, SIV, SV40, Polio, Foamy Virus, dan Herpes B digunakan sebagai model anatomi. Basis data terbuka Mammalian Cranial Photographic Archive 2nd Edition (MCPA2) digunakan untuk analisis kranium. Penelitian dilakukan di Departmen Bedah Saraf RSHS dan Laboratorium Hewan PT. Biofarma pada November 2018?Januari 2019. Struktur tengkorak MF dipelajari analogi seperti pada struktur tengkorak manusia. Analisis uji-t tengkorak jantan dan betina menunjukan rerata panjang kranial (Cranial length, CL) jantan lebih panjang dibanding betina (116.68 vs 102.50 mm, p=0.000); rerata bizygomatic width (BZB) jantan lebih panjang dibanding betina (79.30 vs 69.70 mm, p=0.001); rerata posterior cranial breadth (CBN) jantan lebih panjang dibanding betina (63.40 vs 58.79 mm, p=0.019);dan rerata cranial base length (CBL) jantan lebih panjang dibanding betina (63.32 vs57.55 mm, p=0.001). Tengkorak MF sesuai untuk berbagai penelitian bidang bedah saraf dan neurosains. Karakterisasi kranial dan strukturnya sama dengan yang dimiliki manusia. Struktur kranium MF merupakan model ideal untuk kraniotomi berdasar karakteristik tulang tengkorak, otot temporal besar pada maksilofasial, dan struktur dasar tengkorak.

COMPARISON OF HISTOLOGICAL CHARACTERISTICS OF DRIED AND FRESH AMNION MEMBRANES AND DURA MATER IN NON-HUMAN PRIMATE (MACACA FASCICULARIS) Indah, Astrina Rosaria; Bolly, Hendrikus Masang B.; Faried, Ahmad; Arifin, Muhammad Zafrullah; Achadiyani, Achadiyani; Wirakusumah, Firman Fuad
Majalah Kedokteran Bandung Vol 51, No 1 (2019)
Publisher : Faculty of Medicine, Universitas Padjadjaran

This study aimed to characterize the histological properties of dry-lyophilized amniotic membrane, fresh amniotic membrane (AM), and duramater membrane in search for a biologically-derived material suitable for meninges surface reconstruction. This descriptive study was conducted at the Unit-3 Laboratory of Animal Test of PT. Bio Farma (Persero), Bandung and Cell Biology Laboratory of the Faculty of Medicine, Universitas Padjadjaran Bandung. This study was conducted from 2018-2019. Fresh Macacafascicularis placenta from healthy donors,classified as specific pathogen-free for TB, SIV, SV40, Polio type 1,2,3, Foamy virus and Herpes B virus, were obtained from selected caesarean sections.The harvested dried and fresh AM and duramater membrane were stained with hematoxylin-eosin and prepared for characterization. Histological examination of dry-lyophilized and fresh AM showed similar results. Histologically, AM is represented by a single layer of metabolically-active cuboidal to columnar epithelium with microvilli firmly attached to a basement membrane and an avascular and relatively sparsely populated stroma. Meninges layers consists of 3 layers: duramater, arachnoid membrane, and piamater. Most of these cells have the same characteristics as fibroblasts, including long organelles and nuclei with various levels of fibril formation. The histological study of amniotic membrane and duramater membrane shows comparable results. The AM is a biologically-derived material suitable for meninges surface reconstruction since its histological structure is somewhat similar to that of the duramater. Its structure is ideal for replacing duramater since it has several characteristics, such as having hygroscopic properties, good biocompatibility, relatively easy to apply, and inexpensive. Key words: Dried and fresh amnion membranes, duramater membranes, non-human primate Karakteristik Histologis Membran Amnion Jenis Kering dan Segar dengan Membran Duramater pada Primata Non-Human Macaca fascicularisPenelitian ini bertujuan mengetahui karakteristik histologis membran amnion kering yang diliofilisasi, membran amnion segar, dan duramater, dalam rangka mencari bahan biologis yang cocok untuk rekonstruksi permukaan meninges. Penelitian deskriptif dilakukan di Laboratorium Hewan Uji PT. Bio Farma dan Laboratorium Biologi Sel FK Universitas Padjadjaran periode 2018-2019. Plasenta Primata non-human Macaca fascicularis segar dari donor sehat, yang bebas dari pathogen spesifik TB, SIV, SV40, Polio tipe 1, 2, 3, virus Foamy dan virus Herpes B, diperoleh dari seksio sesarea. Kemudian, dilakukan pewarnaan dengan hematoxylin-eosin untuk membran amnion kering dan segar, serta membran duramater untuk mengetahui karakterisasi histologisnya. Pemeriksaan histologis membran amnion kering-yang aktif bermetabolisme hingga kolumnar dengan mikrovili; melekat kuat pada membran basal dan stroma yang avaskular dan relatif jarang. Lapisan Meninges terdiri dari 3 lapisan: duramater, arachnoid dan piamater. Sebagian besar sel-sel ini memiliki karakteristik yang sama dengan fibroblas. Studi histologis membran amnion dan membran duramater memiliki struktur yang relatif serupa. Membran amnion adalah material yang secara biologis cocok untuk rekonstruksi permukaan meningen, karena struktur histologinya agak mirip dengan duramater. Oleh karena itu secara struktur, membran amnion ideal untuk menggantikan duramater karena memiliki beberapa karakteristik seperti sifat higroskopis, biokompatibilitas baik, mudah diterapkan, dan murah.Kata kunci: Membran amnion segar dan kering, membran duramater, primate non-human

PELATIHAN PENERAPAN STRATEGI BELAJAR “MENGGUNAKAN OTAK” UNTUK PENINGKATAN KEMAMPUAN DAN PRESTASI BELAJAR SISWA SEKOLAH LANJUTAN TINGKAT PERTAMA Hendrikus Masang Ban Bolly; Renny Sulelino
Prosiding Seminar Nasional Pengabdian Kepada Masyarakat Vol 2 (2021): PROSIDING SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT - SNPPM2021
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Negeri Jakarta

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Abstract The human brain has an infinite capacity to collect the latest information, including building sub-systems in learning. The learning process will activate and involve the work of the brain in the learning and memory processes. Understanding how the brain works and the various supporting conditions that support the learning process can be the key to successful learning. Training on the Application of Learning Strategies "Using the Brain" to Improve Students' Learning Ability and Achievement at SLTP Negeri 3 Jayapura aims to provide insight and description to junior high school students on how learning strategies are based on understanding brain performance so that in the end they can improve students' learning abilities and achievements. This training was attended by 30 junior high school students in grades 7, 8, and 9. The training materials provided were the introduction of brain anatomy which plays an important role in the learning process, understanding memory performance, nutrition for the brain, training the brain to think, exercise and exercise for the brain, brain activation to understand, and music for the learner's brain. The training method is carried out directly through interactions in the form of delivering training materials, role-playing, games, and small group practice. The Learning Strategy Using the Brain Module product for junior high school students in the Covid-19 Pandemic Era has also obtained a Copyright letter from the Ministry of Law and Human Rights of the Republic of Indonesia. Pre and post test results showed an increase in students' knowledge of training materials, also showing good seriousness and focus during training. Abstrak Otak manusia memiliki kapasitas tak terhingga untuk mengumpulkan berbagai informasi terbaru, termasuk membangun sub-sistem dalam belajar. Proses belajar akan mengaktivasi dan melibatkan kerja otak dalam proses pembelajaran dan memori. Memahami bagaimana kinerja otak dan berbagai kondisi penunjang yang mendukung dalam proses belajar dapat menjadi kunci keberhasilan belajar. Pelatihan Penerapan Strategi Belajar “Menggunakan Otak” Untuk Peningkatan Kemampuan dan Prestasi Belajar Siswa di SLTP Negeri 3 Jayapura bertujuan untuk memberikan wawasan dan gambaran kepada siswa SLTP tentang bagaimana strategi pembelajaran berbasis pemahaman kinerja otak sehingga pada akhirnya mampu meningkatkan kemampuan dan prestasi belajar siswa. Pelatihan ini diikuti oleh 30 siswa SLTP kelas 7, 8 dan 9. Materi pelatihan yang diberikan yaitu pengenalan anatomi otak yang berperan penting dalam proses belajar, memahami kinerja memori, nutrisi untuk otak, melatih otak berpikir, senam dan olahraga untuk otak, aktivasi otak untuk memahami dan musik untuk otak pembelajar. Metode pelatihan dilakukan secara langung melalui interaksi berbentuk penyampaian materi pelatihan, bermain peran, permainan dan praktik kelompok kecil. Produk Modul Strategi Belajar Menggunakan Otak untuk siswa SLTP di Era Pandemik Covid-19 juga telah memperoleh surat Hak Cipta dari Kemukumham Republik Indonesia. Hasil pre dan post test menunjukkan terjadi peningkatan pengetahuan siswa terkait materi pelatihan, juga menunjukkan keseriusan dan fokus siswa yang baik selama pelatihan.

DETEKSI DAN PEREKRUTAN KASUS KELAINAN BAWAAN SISTEM SARAF PUSAT DI PUSKESMAS WILAYAH KOTA JAYAPURA Hendrikus Masang Ban Bolly
Prosiding Seminar Nasional Pengabdian Kepada Masyarakat Vol 3 (2022): PROSIDING SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT - SNPPM2022
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Negeri Jakarta

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AbstractCongenital central nervous system abnormalities occur in the fruit of pregnancy and are recognized when the newborn is born birth or detected on ultrasound examination when the baby is still in the womb. Master key The management of infants/children with congenital abnormalities of the central nervous system is detection and correction feature maybe. Public outreach activities and training of health workers This puskesmas aims to introduce, help detect and refer to neurosurgeons for necessary medical intervention. Methods of implementing activities include counseling the general public and health workers are carried out through bold Zoom Meeting media; power training special health services are carried out directly at the Puskesmas using the booklet “The Difference Behind Sheets Congenital Brain and Spine”. The training with this theme is the first time it has been conducted in Jayapura, even in Papua. The results that have been achieved from this series of community service programs are: educating the general public and health workers in a courageous manner, special training for health workers Puskesmas and obtained a copyright registration letter from the Ministry of Law and Human Rights of the Republic of Indonesia for the Booklet product Flipchart of Inherited Differences in the Central Nervous System. Abstrak Kelainan bawaan system saraf pusat terjadi sejak dalam buah kehamilan dan diketahui saat bayi baru lahir maupun terdeteksi pada pemeriksaan ultrasonografi saat bayi masih dalam kandungan. Kunci utama penatalaksanaan bayi/anak dengan kelainan bawaan system saraf pusat adalah deteksi dan koreksi kelainan sedini mungkin. Kegiatan penyuluhan masyarakat awam dan pelatihan tenaga kesehatan puskesmas ini bertujuan untuk mengenalkan, membantu mendeteksi dan merujuk ke tenaga ahli bedah saraf untuk dilakukan intervensi medis yang diperlukan. Metode pelaksanaan kegiatan meliputi penyuluhan masyarakat awam dan tenaga kesehatan dilakukan melalui media daring Zoom Meeting; pelatihan tenaga kesehatan khusus dilakukan langsung di Puskesmas menggunakan booklet “Lembar Balik Kelainan Bawaan Otak dan Tulang Belakang”. Pelatihan dengan tema ini merupakan yang pertama kali dilakukan di Jayapura, bahkan di Papua. Hasil yang telah dicapai dari rangkaian program pengabdian ini adalah penyuluhan masyarakat awam dan tenaga kesehatan secara daring, pelatihan khusus tenaga kesehatan Puskesmas serta diperolehnya surat pencatatan hak cipta dari Kemkumham RI untuk produk Booklet Lembar Balik Kelainan Bawaan Sistem Saraf Pusat.

PELATIHAN SELAMATKAN OTAK GENERASI EMAS PAPUA ANTI-ALKOHOLISME UNTUK SISWA SEKOLAH MENENGAH ATAS NEGERI 1 KOTA JAYAPURA Hendrikus Masang Ban Bolly; Renny Sulelino
Prosiding Seminar Nasional Pengabdian Kepada Masyarakat Vol 3 (2022): PROSIDING SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT - SNPPM2022
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Negeri Jakarta

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Abstrak Ketergantungan terhadap minuman beralkohol pada kalangan generasi muda usia produktif di Papua cukup tinggi. Permasalahan ini mengancam masa depan generasi muda oleh karena dampak yang sangat serius terhadap berbagai organ tubuh manusia. Otak merupakan salah satu organ yang dapat terdampak serius akibat alkoholisme. Pelatihan ini didesain sebagai upaya promotive dan preventif terhadap permasalahan alkoholisme di Jayapura. Pelatihan bagi 30 siswa SMA negeri 1 telah dilakukan selama satu hari. Pemberian materi dari instruktur meliputi topik menjaga kesehatan otak, spektrum permasalahan alkoholisme di Indonesia, fetal alcoholic syndrome, aspek genetic dan metabolisme alkohol dalam tubuh manusia, efek alcohol pada berbagai organ tubuh, langkah-langkah mengobati alkoholisne, dan pengembangan strategi penyelesaian permasalahan alkoholisme di Papua. Bersamaan dengan pelaksanaan pelatihan, ditampilkan juga video edukasi permasalahan alkoholisme karya cipta mahasiswa fakultas kedokteran universitas Cenderawasih yang telah memperoleh hak cipta dari kementrian hukum dan hak asasi manusia Republik Indonesua. Selain itu, menjadi satu rangkaian dengan program ini juga dilakukan edukasi melalui program televisi “Teropong Sehat Papua” berjudul Bahaya Alkohol pada kesehatan Otak yang disiarkan oleh TVRI Papua pada 11 Februari 2022. Abstract Dependence on alcoholic beverages among the young generation of productive age in Papua is quite high. This problem threatens the future of the younger generation because of its very serious impact on various organs of the human body. The brain is one of the organs that can be seriously affected by alcoholism. This training is designed as a promotive and preventive effort on the problem of alcoholism in Jayapura. Training for 30 students of SMA Negeri 1 was carried out for one day. Materials provided by the instructor cover the topic of maintaining brain health, the spectrum of alcoholism problems in Indonesia, fetal alcohol syndrome, genetic aspects and normal alcohol metabolism in the human body, the effects of alcohol on various organs of the body, steps to treat alcoholism, and developing strategies for solving alcoholism problems in Papua. Along with the implementation of the training, an educational video on the problem of alcoholism was also shown, created by students of the medical faculty of Cenderawasih University, which has obtained copyright from the Ministry of Law and Human Rights of the Republic of Indonesia. Apart from that, community education is also being carried out as part of this program through the television program "Teropong Sehat Papua" entitled The Dangers of Alcohol on Brain Health which was broadcast by TVRI Papua on 11 February 2022.

EDUKASI MASYARAKAT AWAM PENGURUS GEREJA DALAM RANGKA MENINGKATKAN “STROKE AWARNESS” DI KOTA JAYAPURA Bolly, Hendrikus Masang Ban; Sulelino, Renny; Sitanggang, Prysta Aderlia
Jurnal Media Tropika Vol 4 No 2 (2024): Jurnal Media Tropika
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/mediatropika.v4i2.18809

A stroke is an acute attack due to blockage or rupture of blood vessels in the brain. Negligence and delay in fast and appropriate treatment will increase the death rate and permanent disability in patients with stroke. Education for promotive and preventive purposes related to stroke for church administrators is critical considering their roles and functions. This "stroke awareness" educational activity aims to provide knowledge (cognitive) and initial skills for stroke patient caregivers, as well as containing promotive and preventive content to improve brain health. The implementation method is interactive in-house training including material delivery, video sessions, and simple simulations. The activity was implemented in two Catholic churches in Jayapura City attended by 43 church administrators, and the training duration of around 150 minutes. This activity is crucial to provide basic knowledge about all aspects of stroke, starting from the causes, risk factors, course of the disease, complications, treatment, and estimated patient outcomes as well as tips and tricks for maintaining brain health. The simulations include recognizing early symptoms, initial skill in management of the patients at the scene and transferring patients to the hospital. Educational activities like this are recognized as very beneficial and are recommended to be carried out routinely to reach all people. Public education related to non-infectious diseases such as stroke which statistically tends to increase currently needs to be done routinely to improve the health of the community. The church can be a potential target for activating healthy lifestyles and reducing the risk of stroke in the community.

HELMET USE COMPLIANCE SURVEY FOR CRANIOFACIAL TRAUMA PREVENTION AMONG MOTORCYCLISTS IN JAYAPURA CITY RING ROAD Bolly, Hendrikus Masang Ban; Trajanus Laurens Yembise
Jurnal Rekonstruksi dan Estetik Vol. 9 No. 2 (2024): Jurnal Rekonstruksi dan Estetik, December 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jre.v9i2.64397

Highlights: This study provides insights on helmet compliance among motorcyclists in Jayapura City to help prevent head injuries. The analysis shows non-compliance with helmets, especially on the Jayapura Ring Road, where up to four people ride a single motorbike. Consequently, accidents causing head injuries result in greater health and humanitarian impacts. Abstract: Introduction: Compliance with helmet use by motorcycle riders and passengers passing through the highway is one of the important factors in preventing craniofacial injuries and head injury. This study designed to survey and evaluate the compliance with helmet use among motorcyclists and passengers on the ring road in Jayapura City. Methods: This time-based survey study observed compliance with helmet use by motorcycle riders and passengers passing through the Jayapura city ring road for 14 days of observation at three-time orders (morning, afternoon, and evening). Analysis of the collected data was carried out descriptively. Results: The results showed that during the study period, there were 6,411 motorcycles passing through, 18,602 motorcycle passers-by were at moderate risk of injury due to not wearing helmets (MR-IV) and 11,849 were at high risk (HR-II). The peak of non-compliance with helmet use occurred in the afternoon period (T3). The results showed that 71.92% of the HR-V group did not obey helmet use; 184.82% of the HR-II group did not obey helmet use. While non-compliance with helmet use in the MR-IV group even reached 290.15%. Conclusion: Helmet use compliance among motorcycle riders and passengers on the Jayapura Ring Road is low, increasing their risk of head injuries in accidents. This highlights the need for strategies to reduce helmet non-compliance in Jayapura City. The study focuses on one of the busiest routes, and further research is needed to assess helmet compliance on other busy routes in the city for a more comprehensive understanding.

Evaluation Of Traumatic Brain Injuries Due To Alcohol Intoxication: Study In Central Hospital In West Java Hendrikus Masang Ban Bolly; Agung Budi Sutiono; Ahmad Faried; Trajanus Laurens Yembise; Muhammad Zafrullah Arifin; Benny Atmadja Wirjomartani
JURNAL WIDYA MEDIKA Vol. 6 No. 1 (2020): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v6i1.2501

Background: Alcohol intoxication is one of the predisposing factors for the incidence of traumatic brain injury (TBI). At present, there are no hospital-based specific data that provide TBI prevalence rates due to alcohol intoxication, especially in West Java. Objective: This study aims to make descriptive observations about the incidence of TBI due to alcohol intoxication in one of the central referral hospitals in West Java. Method: A retrospective cross-sectional study was carried out involving 10,662 TBI patients recorded in the emergency department database and the Department of Neurosurgery daily case database in the period 2012 to 2018. All data relating to the two items were analyzed. Alcohol intoxication is known from a history of autoanamnesis, alloanamnesis, and the subjective identification of the examiner of alcohol odor on the breath in TBI patients who enter the emergency room. Statistical cross-tabulations were performed to present clinical and demographic phenomena in TBI cases due to alcohol intoxication. Results: The analysis showed that the prevalence of alcohol intoxication in TBI cases was 4.77% (N = 507), all of which were due to motor vehicle accidents. Mean age of 26.44 ± 9.32 years (median 24 and range 12-64). The predominant age in TBI cases due to alcohol intoxication was in the age range of 20-30 years (44.2%), and male sex 92.7%. Most cases occurred in May (12%) and on Saturdays. Based on the consciousness assessment, initial Glasgow Coma Scale in emergency department were 14 (35.9%) and classified as mild TBI (69.2%). Subarachnoid hemorrhage and cerebral contusion are predominantly lesions found on CT scans of patients (2.2%), anterior skull base fractures of 8.1%, and linear fractures (5.1%) are the dominant extracranial lesions. Soft tissue lacerations are found in 16% of all cases. Craniotomy surgery was performed in 3.6% of patients for epidural, intracerebral, and subdural hemorrhage lesion evacuation as well as correction of depressed skull fractures. About 45% were treated for a minimum of three days to observe changes in their consciousness status before discharge. Conclusion: Alcohol consumption before the head injury in motor vehicle accidents has a relationship with various complications. Alcohol intoxication is a complex issue, and more research needs to be done to create comprehensive prevention programs and regulations.

MANAGEMENT OF GIANT TUBERCULOMA IN A YOUNG PAPUAN MAN: CASE REPORT AND LITERATURE REVIEW Bolly, Hendrikus Masang Ban; Sulelino, Renny
JURNAL WIDYA MEDIKA Vol. 10 No. 2 (2024): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v10i2.5980

Tuberculoma infection in Papua is still quite high. Tuberculoma is a focus of caseous tubercles found in the brain parenchyma caused by the bacteria Mycobacterium tuberculosis. This study aims to report the outcomes of tuberculosis patients who underwent craniotomy resection of large tuberculoma lesions and continued with therapy using anti-tuberculosis drugs (OAT). There are challenges in the radiological and clinical diagnostic approaches to tuberculoma lesions in these patients who have no history of previous pulmonary tuberculosis infection. A definite diagnosis of tuberculoma is obtained from the establishment of anatomical pathology diagnostics so that the patient is then given FDC category I of anti-tuberculosis drugs for up to 9 months. The patient showed clinical improvement and brain tissue repair after surgery as evidenced by neuroimaging evaluation 7 months after surgery. Management of tuberculosis in Papua requires an educational focus on increasing the synergy of promotive and preventive aspects and finding new cases of tuberculoma to be treated as early as possible.

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